Multiple Dural Arte Rio Venous Malformations Coming From The

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    Multiple DuralMultiple Dural ArteriovenousArteriovenous

    Malformations Coming from theMalformations Coming from the

    Three Branches of the AnteriorThree Branches of the AnteriorCerebralCerebral ArteriesArteries

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    The PatientThe Patient

    48 year old, Male

    A stevedore

    Chief Complaint:

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    History of Present IllnessHistory of Present Illness

    2 months PTA2 months PTA

    Widebased gait

    headacheMemory

    lapses

    Irritability/low

    attention

    Decreasedlibido

    1 year PTA1 year PTA

    limping imbalance

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    Past Medical HistoryPast Medical History

    CraniectomyCraniectomy

    3 years ago

    EpiduralEpidural

    hematomahematoma

    due to traumadue to trauma

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    Personal/ Social HistoryPersonal/ Social History

    Non- smoker

    Occasional Alcoholic beverage

    drinker History of marijuana and cough syrup

    intake in his early 20s.

    Salesman/ Farm Manager Stevedore

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    FamilyHistoryFamilyHistory

    Cerebrovascular Accident

    Hypertension

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    Review of SystemReview of System

    Skin: (-) lesion, brown hair

    Lymph node: (-) lymphadenopathy

    Bones, Joints and Muscle: (-) fractures, (-)dislocations (-) swelling

    Head: (+) headache(+) headache, (-) seizure

    Eyes: (-) blurring of vision, (-) discharges

    Ears: (-) deafness, (-) discharge, (-) pain

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    Review of SystemReview of System

    Nose: (-) discharge, (-) epistaxis

    Neck: (-) enlarge lymph nodes

    Respiratory: (-) cough, (-) dyspneaCardiovascular: (-) chest pain, (-)

    exertional dyspnea, (-) orthopnea

    Gastrointestinal: (-) diarrhea, (-)nausea, (-) vomiting

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    Review of SystemReview of System

    Nervous System:

    (-) photophobia,(-) blurring of vision,

    (-) limitation in motion of neck

    Allergies: None

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    Physical ExaminationsPhysical Examinations

    Gen Survey: awake, conscious, coherent,ambulatory, not in CR distress

    Vi

    talSi

    gns:BP=1

    20/80; CR-84;T=37

    ; RR=1

    8

    HEENT: pink palpebral conjunctiva, anictericsclera, (-) tonsillo pharyngeal congestion, (-)CLAD (-) bruit

    Precordium: adynamic, PMI at 5th ICSMCL,

    (-) murmur, (-) heaves

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    Physical ExaminationPhysical Examination

    CHEST: equal chest expansion, clearbreath sounds, (-) retraction, (-)

    lagging

    Abdomen: flat, soft, NABS, non tender,(-) organomegaly

    Extremities: full equal pulses, (-) edema

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    Neurologic ExaminationNeurologic Examination

    Mental Status Exam:

    Medium built, fairly groomed

    abulic speech

    Good eye contact

    Depressed MoodFlat affect

    Oriented to person, place time and situation

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    MiniMini Mental Status ExamMental Status ExamMaximum

    Score

    PatientsScore Questions

    5 4 What is the year? Season? Date? Day of the week? Month?

    5 5 Where are we now: State? County? Town/city? Hospital? Floor?

    3 3 The examiner names three unrelated objects clearly and slowly, thenasks the patient to name all three of them. The patients response is

    used for scoring. The examiner repeats them until patient learns all of

    them, if possible. Number of trials: ___________

    5 2 I would like you to count backward from 100 by sevens. (93, 86, 79,

    72, 65, ) Stop after five answers.

    Alternative: Spell WORLD backwards. (D-L-R-O-W)

    3 1 Earlier I told you the names of three things. Can you tell me what those

    were?

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    2 2 Show the patient two simple objects, such as a wristwatch and a

    pencil,

    and ask the patient to name them.

    1 0 Repeat the phrase: No ifs, ands, or buts.

    3 3 Take the paper in your right hand, fold it in half, and put it on the

    floor.

    (The examiner gives the patient a piece of blank paper.)

    1 1 Please read this and do what it says. (Written instruction is Close

    your eyes.)

    1 1 Make up and write a sentence about anything. (This sentence mustcontain a noun and a verb.)

    1 0 Please copy this picture. (The examiner gives the patient a blank

    piece of paper and asks him/her to draw the symbol below. All 10

    angles must be present and two must intersect.)

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    Mini Mental Status Examination:22

    Clock Drawing test was 3 GPCOG Screening Test Score of3

    Clinical Dementia Rating of 1

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    Cranial Nerve ExaminationCranial Nerve Examination

    CN I can smell

    CN II, III pupils equally reactive to light Fundoscopy:

    OD OS

    ROR (+) (+)

    DISC clear disc margin clear disc margin

    AVR 1:3 1:3

    Venules Normal Normal

    Exudates (-) (-)

    Hemorrhage (-) (-)

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    CN III,IV, VI: intact extraocular muscle

    CN V: (+) corneal reflex

    (+) can clench teeth

    CN VII: (-) facial asymmetry, wrinkling of theforehead are equal and symmetrical

    CN VIII: can hear

    CN IX: (+) gag reflex

    CN X: (+) gag reflex CN XI: can shrug shoulder

    CN XII: tongue is at the midline

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    5/5 4/5

    4/55/5

    100% 100%

    100% 100%

    motor sensory

    R L

    R L

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    ++

    ++ ++

    ++

    DTR

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    Nuchal rigidity(-)

    Brudzinski: (-) Kernigs: (-)

    Babinski: (-)

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    Coordination:

    No tremors

    Can button his shirt and write word legibly

    Slight loss of balance when allowed to standwithout support

    Finger to nose: Normal

    Rapid Alternating Movement: canpronate and supinate the hand, howeverhowever

    slowing when ask to change the directionslowing when ask to change the direction

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    DiagnosticsDiagnostics

    CBC: Normal ECG: Sinus Rhythm

    Crea: 85.20

    Na: 151.00

    K: 4.0

    Chest Xray: Normal

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    Ct SCANCt SCAN

    Plain Contrast

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    `4 Vessel Angiogram: AV MAL`4 Vessel Angiogram: AV MAL

    AP View-1- Right AP view -2-Right

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    AngiographyAngiography

    Lateral View -1 Lateral View -2

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    angiographyangiography

    AP View- 1-Left Ap view -2-left

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    Salient FeaturesSalient Features

    48/M

    Disorientation

    Headache Right sided weakness

    Decreased libido and poor attention

    Depressed mood, flat affect

    Monotonous and abulic speech Alcoholic bev drinker

    (+) history of substance abuse (cannabis)

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    Salient FeaturesSalient Features

    Cranial nerves: intact

    Motor: 4/5 on both the upper & lower ext

    Tendency to fall to the right

    Mild dysdiadochokinesia

    Negative meningeal signs

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    Differential DiagnosisDifferential Diagnosis

    Multiple Emboli:1. Cardiac

    2. Infectious origin

    Multiple Cerebral

    Aneurysms

    Intracranial

    Hemorrhage

    CavernousMalformations

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    Salient FeaturesSalient Features

    48/M48/M

    DisorientationDisorientation

    HeadacheHeadache

    Right sided weaknessRight sided weakness

    Decreased libido and poor attentionDecreased libido and poor attention

    Depressed mood, flat affectDepressed mood, flat affectMonotonous andMonotonous and abulicabulic speechspeech

    AlcoholicAlcoholic bevbev drinkerdrinker

    (+) history of substance abuse (cannabis)(+) history of substance abuse (cannabis)

    Cranial nerves: intactCranial nerves: intact

    Motor: 4/5 on both the upper & lower ext

    Motor: 4/5 on both the upper & lower extTendency to fall to the rightTendency to fall to the right

    MildMild dysdiadochokinesiadysdiadochokinesia

    NegativeNegative meningealmeningeal signssigns

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    Multi le ere r lMulti le ere r l rteri ve usrteri ve us

    Malf r ati sMalf r ati s

    Rare: 0.3- 4.9% of all AVMS

    1.84% had multiple AVM

    Dural AVMS:10-

    14% of AVM

    S

    Female Preponderance

    5th to 6th Decade

    Left sided preponderance

    5th to 6th Decade

    1.84% had multiple AVM

    Left sided preponderance

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    Dural AVMsDural AVMs

    nosoligically heterogenous group oflesions linked by similar architecture

    Results to sinus thrombos

    is 72%

    May also precede their appearance

    Signs and Symptoms*** location of the

    lesionProgesssive memory impairment- 6-12%

    Symptoms and Signs:Symptoms and Signs:

    Memory impairmentMemory impairment-- 66--12%12%

    FocalFocal neurodeficitsneurodeficits-- 55--14%14%HeadacheHeadache 4343--50%50%

    Bruits/Bruits/ timmitustimmitus-- 6767--92%92%

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    In our patientWIn our patientW

    Cognitive impairment

    Anterior cerebral arteries involvement

    Result to:

    ABULIA PARAPLEGIA

    Tests:

    MM

    SE~ 22/30: m

    ild cogn

    itive

    impa

    irment

    Clockdrawing test: minor deviations

    GPCOG: cognitive impairment

    Clinical Dementia Rating- Mild Dementia

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    Dural AVMsDural AVMs

    Course : BENIGN

    Treatment:

    ~expectant observation to more involvedmultimodality treatment interventionssuch as both transarterial and transvenousembolization.

    IN ourPATIENT:Memantin ~16th week of medication

    No signs of progression of the symptoms

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    ConclusionConclusion

    Multiple Dural AV Malformationspresent according to their anatomical

    location

    Disorientation and memory lapses~ ACAterritory

    Common manifestations with unsual

    diagnosis AVMs- 0.3%-4.9% had multiple

    involvements

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    ConclusionConclusion

    After extensive research

    NO PUBLISHED INFORMATION ONINVOLVEMENT OF ALL 3 BRANCHES OF

    THE BILATERAL ANTERIOR CEREBRALARTERIES

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    GOOD DAY!!!!GOOD DAY!!!!