MRC Questionnaire (MRCQ) on Respiratory Symptoms

1
Occupational Medicine 2007;57:388 doi:10.1093/occmed/kqm051 MRC questionnaire (MRCQ) on respiratory symptoms A brief history The Medical Research Council Questionnaire (MRCQ) was developed by researchers at the Medical Research Council, UK, as a tool to study respiratory epidemiology in communities and occupational groups [1]. It reliably relates symptoms and lung function and has been in use for almost 50 years. The 1976 version is reproduced in a current publication [2]. Instructions on its use can be obtained from the authors. A subsequent version includes questions that are directed to identifying asthma [3]. Items In its usual form, the MRCQ comprises 17 questions on respiratory symptoms (cough, phlegm, breathlessness, wheeze and chest illnesses, now and during the past 2 years), detailed questions on smoking history and a check-list on past illnesses. Validity Wording of questions, follow-up questions, definitions and interpretation of responses are standardized and al- ternative questions have been prepared for special cir- cumstances, for example, shift working. The intensity of symptoms is not covered but can be scored separately [4]. The MRCQ provides a system for scoring respiratory symptoms [5] and identifying underlying factors includ- ing smoking, previous chest illnesses and occupational dusts and vapours. Reproducibility is achieved by having the questions asked by an observer who had previously used the training manual and cassette. However, a version for self-administration is also available. The questions on breathlessness are widely used for grading this symptom, but there is more than one scoring system, so the grades should be defined. In subjects with chronic respiratory disorders, the grades of breathless- ness are weakly correlated with forced expiratory volume (FEV 1 ). However, the correlation is higher with ventila- tion during sub-maximal exercise [6] and with quality of life as assessed by a quality of life questionnaire [7]. These two features appear to be co-linear and this possi- bility should be explored further. Key research The MRCQ is recommended for use in epidemiological and occupational respiratory surveys and as part of a con- sultation for respiratory symptoms or assessment of lung function. Where appropriate, the screening can be ex- panded with additional questions on ischaemic heart disease [8], asthma [9] or exposure to occupational re- spiratory hazards such as coal or cotton dust, asbestos fibres or fumes from welding [10]. J. E.Cotes 1 and D. J. Chinn 2 References 1. Medical Research Council on the Aetiology of Chronic Bronchitis. Standardised questionnaire on respiratory symptoms. Br Med J 1960;2:1665. 2. Cotes JE, Chinn DJ, Miller MR. Lung Function: Physiology Measurement and Application in Medicine: 6th ed. Oxford Blackwell Publishing 2006;87–91. 3. Cotes JE. Medical Research Council Questionnaire on respiratory symptoms. Correspondence. Lancet 1987;2: 1028. 4. Field GB. The application of a quantitative estimate of cough frequency to epidemiological surveys. Int J Epidemiol 1974;3:135–143. 5. Medical Research Council. Definition and classification of chronic bronchitis for clinical and epidemiological purpo- ses. Lancet 1965;1:775–779. 6. Cotes JE, Zejda J, King B. Lung function impairment as a guide to exercise limitation in work-related lung disor- ders. Am Rev Respir Dis 1988;137:1089–1093. 7. Jones PW. Quality of life measurement for patients with diseases of the airways. Thorax 1991;46:676. 8. Rose G, McCartney P, Reid DD. Self-administration of a questionnaire on chest pain: intermittent claudication. Brit J Prev Soc Med 1977;31:42–48. 9. Burney P, Chinn S. Developing a new questionnaire for measuring the prevalence and distribution of asthma. Chest 1987;91(Suppl.):79S–83S. 10. Chinn DJ, Cotes JE, El-Gamal FM et al. Respiratory health of young shipyard welders and other tradesmen studied cross-sectionally and longitudinally. Occup Environ Med 1995;55:33–42. 1 School of Health Science, University of Durham, Durham, UK. 2 Department of Community Health Sciences, University of Edinburgh, Edinburgh, UK. Correspondence to: e-mail: [email protected] Ó The Author 2007. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: [email protected] by guest on April 22, 2014 http://occmed.oxfordjournals.org/ Downloaded from

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Occupational Medicine 2007;57:388doi:10.1093/occmed/kqm051

MRC questionnaire (MRCQ) on respiratory

symptoms

A brief history

The Medical Research Council Questionnaire (MRCQ)

was developed by researchers at the Medical Research

Council, UK, as a tool to study respiratory epidemiology

in communities and occupational groups [1]. It reliably

relates symptoms and lung function and has been in use

for almost 50 years. The 1976 version is reproduced in

a current publication [2]. Instructions on its use can be

obtained from the authors. A subsequent version includes

questions that are directed to identifying asthma [3].

Items

In its usual form, the MRCQ comprises 17 questions on

respiratory symptoms (cough, phlegm, breathlessness,

wheeze and chest illnesses, now and during the past 2

years), detailed questions on smoking history and

a check-list on past illnesses.

Validity

Wording of questions, follow-up questions, definitions

and interpretation of responses are standardized and al-

ternative questions have been prepared for special cir-

cumstances, for example, shift working. The intensity of

symptoms is not covered but can be scored separately [4].

The MRCQ provides a system for scoring respiratory

symptoms [5] and identifying underlying factors includ-

ing smoking, previous chest illnesses and occupational

dusts and vapours. Reproducibility is achieved by having

the questions asked by an observer who had previously

used the trainingmanual and cassette. However, a version

for self-administration is also available.

The questions on breathlessness are widely used for

grading this symptom, but there is more than one scoring

system, so the grades should be defined. In subjects with

chronic respiratory disorders, the grades of breathless-

ness are weakly correlated with forced expiratory volume

(FEV1). However, the correlation is higher with ventila-

tion during sub-maximal exercise [6] and with quality of

life as assessed by a quality of life questionnaire [7].

These two features appear to be co-linear and this possi-

bility should be explored further.

Key research

The MRCQ is recommended for use in epidemiological

and occupational respiratory surveys and as part of a con-

sultation for respiratory symptoms or assessment of lung

function. Where appropriate, the screening can be ex-

panded with additional questions on ischaemic heart

disease [8], asthma [9] or exposure to occupational re-

spiratory hazards such as coal or cotton dust, asbestos

fibres or fumes from welding [10].

J. E.Cotes1 and D. J. Chinn2

References

1. Medical Research Council on the Aetiology of Chronic

Bronchitis. Standardised questionnaire on respiratory

symptoms. Br Med J 1960;2:1665.

2. Cotes JE, Chinn DJ, Miller MR. Lung Function: Physiology

Measurement and Application in Medicine: 6th ed. Oxford

Blackwell Publishing 2006;87–91.

3. Cotes JE. Medical Research Council Questionnaire on

respiratory symptoms. Correspondence. Lancet 1987;2:

1028.

4. Field GB. The application of a quantitative estimate of

cough frequency to epidemiological surveys. Int J Epidemiol

1974;3:135–143.

5. Medical Research Council. Definition and classification of

chronic bronchitis for clinical and epidemiological purpo-

ses. Lancet 1965;1:775–779.

6. Cotes JE, Zejda J, King B. Lung function impairment as

a guide to exercise limitation in work-related lung disor-

ders. Am Rev Respir Dis 1988;137:1089–1093.

7. Jones PW. Quality of life measurement for patients with

diseases of the airways. Thorax 1991;46:676.

8. Rose G, McCartney P, Reid DD. Self-administration of

a questionnaire on chest pain: intermittent claudication.

Brit J Prev Soc Med 1977;31:42–48.

9. Burney P, Chinn S. Developing a new questionnaire for

measuring the prevalence and distribution of asthma. Chest

1987;91(Suppl.):79S–83S.

10. Chinn DJ, Cotes JE, El-Gamal FM et al. Respiratory health

of young shipyard welders and other tradesmen studied

cross-sectionally and longitudinally. Occup Environ Med

1995;55:33–42.

1School of Health Science, University of Durham, Durham, UK.

2Department of Community Health Sciences, University of Edinburgh,

Edinburgh, UK.

Correspondence to: e-mail: [email protected]

� The Author 2007. Published by Oxford University Press on behalf of the Society of Occupational Medicine.All rights reserved. For Permissions, please email: [email protected]

by guest on April 22, 2014

http://occmed.oxfordjournals.org/

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nloaded from