MOI-201 Insecticide

Julie Versman, VP Marketing 530-750-2800 info@MarroneOrganics.com

Founded 2006 by Pam Marrone, Davis CA

Natural products that focus on unmet needs for weed,

pest and plant disease management.

Product discovery from 1) in-house screening

2) in-licensing

A rich pipeline of products in development with

applications for specialty crops

Marrone Organic Innovations

Source: plant extracts from Asia; used for many years

as a medicinal compound

Target Pests: Sucking and chewing insects

Mode of Action: Unknown; Different than pyrethrum or neem

Mortality by both feeding and contact in 24-48 hrs

Biodegradable; 7-14 day spray intervals

Global registration in progress

Territory: MOI has license in NAFTA

MOI-201 Insecticide Overview

MOI 201 InsecticideMOI 201 Insecticide

Warehouse with Locust SeedsN

N

O

H

H

H

H H

H

O

Extracted Insecticidal Compounds

N

N

O

H

H

H H

H

H

Sophora tree

Lab & Greenhouse Efficacy

Field Data (Asia) Ectropis obliqua (Tea Caterpillar)

TrialPercent

Control (%)

Dose(Fold

dilution)

Days After Treatment

188.797.3

1200 800

55

156.7 91.0

1200 800

1010

281.391.9

1200 800

22

288.493.1

800800

510

0.6% AI (before dilution) for MOI 201No significant difference from es-fenvalerate

Field Data (Asia) - Ectropis obliqua (Tea Caterpillar)

Treatments Dilution 2 DAT 7 DAT 14 DAT

0.6% AI 800 85.17 90.19 86.07

0.6% 1000 83.01 87.21 84.58

0.6% 1200 78.11 80.98 74.16

0.36% 1000 77.90 81.09 75.55

Esfenvalerate 5 EC

2000 82.18 85.66 84.02

Untreated check

Water 0 0 0

Percent Mortality

Field Data (Asia) - Plutella xylostella (Cabbage)

Treatment 20 27 33 40 47 54 61DAT

Untreated Rates 4.5 36.0 87.8 140.5 176.3 230.8 304.3a

Success 1.0L/ha 4.0 4.8 5.3 5.8 6.0 6.0 7.8e

Polycron 1.0L/ha 5.3 8.5 18.0 24.0 29.8 40.8 53.5c

Cyhalothrin 0.5L/ha 1.8 6.8 21.3 41.5 64.3 90.5 117.8b

MOI 201 0.09% 3.8 7.7 9.8 12.0 14.3 18.0 29.8d

MOI 201 0.18% 2.5 4.3 6.8 8.0 8.8 13.0 25.0d

MOI 201 0.28% 2.3 2.5 2.5 3.0 4.0 4.3 6.3e

MOI 201 0.375% 20 5.3 5.3 5.0 7.0 7.3 8.3e

Cumulative DBM larvae/10 Plants

MOI 201 rates are percent of 0.6% AI

Registration may be biochemical (BPPD) or chemical (RD) depending on mode of action

Registered in China and a few other Asian countries

6 pack End Product done (0.6 and 2.4% AI) - no issues

6-pack on TGAI completed; no issues

Ecotox in progress - no issues thus far

Target EPA submission date – 1st half 2009

Regulatory/Toxicology

Ornamentals - whitefly, thrip, mealybug, aphid, mites

Vegetables - whitefly, aphid, mite, cucumber beetle, caterpillar

Fruit/vines - caterpillars, plum curculio, mites, aphids, mealybug

Turf: grub, webworms, chinch bugs

Row crops: soybean and cotton aphid

Potential IR-4 projects

MOI-201 Insecticide

Julie Versman, VP Marketing

530-750-2800

info@MarroneOrganics.com

www.MarroneOrganicInnovations.com