Moderator - ISICEMModerator : Jacques Duranteau (Le Kremlin-Bicêtre , France) Moderator : Laurence...

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Tuesday 15 September 2020 - AM ROOM : HLB Room Opening [Standard presentation] Moderator : Maurizio Cecconi (Rozzano, MI, Italy) Moderator : Michael A Matthay (San Francisco, United States) 8:30 - 8:50 - Welcome: 40 years of intensive care and emergency medicine 8:55 - 9:15 - Report of the Round Table conference on ‘ICU populations: from syndromes to phenotypes’ Carolyn S Calfee (San Francisco , United States), Anthony Gordon (London , United Kingdom) 9:20 - 9:35 - The Max Harry Weil Memorial lecture: lessons from history Mervyn Singer (London, United Kingdom) 9:40 - 9:55 - Lessons from the recent COVID-19 pandemic (TBA) 10:00 - 10:15 - Consciousness in coma Steven Laureys (Liège , Belgium) 10:20 - 10:30 - Film of the 40th Anniversary Antibiotic therapy: for how long? [Standard presentation] Moderator : Mark Mikkelsen (Philadelphia, United States) Moderator : Michael Mansour (Boston, United States) 11:00 - 11:15 - De-escalation? Jean–François Timsit (Paris, France) 11:15 - 11:30 - When to stop them? Hallie Prescott (Ann Arbor, United States) 11:30 - 11:45 - Using procalcitonin to decide Andrea Kwa (Singapore, Singapore) 11:45 - 12:00 - Is the question different for MDR infections? Michael S Niederman (New York, United States) 12:00 - 12:15 - Discussion

Transcript of Moderator - ISICEMModerator : Jacques Duranteau (Le Kremlin-Bicêtre , France) Moderator : Laurence...

Tuesday 15 September 2020 - AM

ROOM : HLB Room Opening [Standard presentation] Moderator : Maurizio Cecconi (Rozzano, MI, Italy) Moderator : Michael A Matthay (San Francisco, United States) 8:30 - 8:50 - Welcome: 40 years of intensive care and emergency medicine

8:55 - 9:15 - Report of the Round Table conference on ‘ICU populations: from syndromes to phenotypes’Carolyn S Calfee (San Francisco , United States), Anthony Gordon (London , United Kingdom)

9:20 - 9:35 - The Max Harry Weil Memorial lecture: lessons from historyMervyn Singer (London, United Kingdom)

9:40 - 9:55 - Lessons from the recent COVID-19 pandemic (TBA)

10:00 - 10:15 - Consciousness in comaSteven Laureys (Liège , Belgium)

10:20 - 10:30 - Film of the 40th Anniversary

Antibiotic therapy: for how long? [Standard presentation] Moderator : Mark Mikkelsen (Philadelphia, United States) Moderator : Michael Mansour (Boston, United States) 11:00 - 11:15 - De-escalation?Jean–François Timsit (Paris, France)

11:15 - 11:30 - When to stop them?Hallie Prescott (Ann Arbor, United States)

11:30 - 11:45 - Using procalcitonin to decideAndrea Kwa (Singapore, Singapore)

11:45 - 12:00 - Is the question different for MDR infections?Michael S Niederman (New York, United States)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Gold Hall Early mobilization and rehabilitation [Standard presentation] Moderator : E Wesley Ely (Nashville, United States) Moderator : Jeremy Cohen (Brisbane, Australia) 11:00 - 11:15 - The complex interplay between psychology and physiologyStephen Brett (London , United Kingdom)

11:15 - 11:30 - We must do it better!Paul Wischmeyer (Durham, United States)

11:30 - 11:45 - Functional and psychological recovery after resuscitation and the ICUClifton Callaway (Pittsburgh, United States)

11:45 - 12:00 - ICU-acquired weakness and ICU mobilityCatherine L Hough (Seattle, United States)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : Gold Hall Mechanisms in sepsis [Standard presentation] Moderator : Michael A Matthay (San Francisco, United States) Moderator : Massimo Antonelli (Rome, Italy) 13:45 - 14:00 - Sepsis-associated endotheliopathyVladimir Cerny (Usti nad Labem, Czech Republic)

14:00 - 14:15 - Sepsis-associated coagulopathyJerrold H Levy (Durham, United States)

14:15 - 14:30 - Understanding mitochondrial functionMervyn Singer (London, United Kingdom)

14:30 - 14:45 - Understanding mitochondrial dysfunctionArthur van Zanten (Ede, Netherlands)

14:45 - 15:00 - Energy metabolism in immune cellsTom van der Poll (Amsterdam , Netherlands)

15:00 - 15:15 - Discussion

15:15 - 15:30 - The complex role of endotoxinPeter Pickkers (Nijmegen, Netherlands)

15:30 - 15:45 - Sepsis-associated myocardial dysfunction Hector R Wong (Cincinnati , United States)

15:45 - 16:00 - Sepsis-associated encephalopathy Paul Vespa (Los Angeles , United States)

16:00 - 16:15 - Sepsis-associated renal dysfunctionJay Koyner (Chicago, United States)

16:15 - 16:30 - The emerging role of the gut microbiomeHallie Prescott (Ann Arbor, United States)

16:30 - 16:45 - Discussion

16:45 - 17:00 - Break

Has the epidemiology of sepsis changed? [Standard presentation] Moderator : Andrea Kwa (Singapore, Singapore) Moderator : Massimo Girardis (Modena , Italy) 17:00 - 17:15 - What the data actually showDerek C Angus (Pittsburgh , United States)

17:15 - 17:30 - Have the numbers changed?Jean-Louis Vincent (Brussels , Belgium)

17:30 - 17:45 - Standardized criteria may give a better viewManu Shankar–Hari (London, United Kingdom)

17:45 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Copper Hall The right time to intubate the trachea [Standard presentation] Moderator : Vladimir Cerny (Usti nad Labem, Czech Republic) Moderator : Giacomo Bellani (Monza, Italy) 11:00 - 11:15 - In CPRLars Wiuff Andersen (Aarhus, Denmark)

11:15 - 11:30 - In shockWesley Self (Nashville, United States)

11:30 - 11:45 - In respiratory failureOriol Roca (Barcelona , Spain)

11:45 - 12:00 - In immunocompromised patientsRémi Coudroy (Poitiers, France)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : Copper Hall New antibacterial agents [Standard presentation] Moderator : Herwig Gerlach (Berlin , Germany) Moderator : Thierry Calandra (Lausanne , Switzerland) 13:45 - 14:00 - For extensively drug-resistant Gram-negative infectionJean–François Timsit (Paris, France)

14:00 - 14:15 - For severe respiratory infectionMichael S Niederman (New York, United States)

14:15 - 14:30 - Patient profiling for new beta-lactams/beta-lactamase inhibitorsMatteo Bassetti (Genova, Italy)

14:30 - 14:40 - Discussion

14:40 - 14:55 - There is no shortage of new antibioticsTobias Welte (Hannover , Germany)

14:55 - 15:10 - We could also use anti-infectious monoclonal antibodiesBruno François ( Limoges , France)

15:10 - 15:25 - We could also use bacteriophagesXavier Wittebole (Brussels, Belgium)

15:25 - 15:40 - Discussion

Diagnostic tools for infection and sepsis [Standard presentation] Moderator : Matteo Bassetti (Genova, Italy) Moderator : Elisabeth Riviello (Boston, United States) 15:40 - 15:55 - Studies on biomarkers are sometimes hard to interpretHerwig Gerlach (Berlin , Germany)

15:55 - 16:10 - Early NO detection: the PROUD paradigmEvangelos Giamarellos–Bourboulis (Athens, Greece)

16:10 - 16:25 - Biomarker discovery and developmentHector R Wong (Cincinnati , United States)

16:25 - 16:40 - How metagenomics can aid diagnosisCarolyn S Calfee (San Francisco , United States)

16:40 - 17:00 - Discussion

17:00 - 17:15 - Leukocyte markersManu Shankar–Hari (London, United Kingdom)

17:15 - 17:30 - How biomarkers can guide therapyMichael Mansour (Boston, United States)

17:30 - 17:45 - We need multianalyte monitoringGrant Bochicchio (St Louis, United States)

17:45 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Salle M (Bozar) Critical care in environments with limited resources [Standard presentation] Moderator : John C Marshall (Toronto , Canada) Moderator : Peter Pickkers (Nijmegen, Netherlands) 11:00 - 11:15 - ARDS from Berlin to Kigali: with only ultrasound and pulse oximetryElisabeth Riviello (Boston, United States)

11:15 - 11:30 - How to generalize high quality sepsis careFlavia Machado (Sao Paulo , Brazil)

11:30 - 11:45 - Simplified guide for fluid resuscitationDaniel De Backer (Brussels, Belgium)

11:45 - 12:00 - Remote guidance through modern communication systemsManu Malbrain (Brussels, Belgium)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : Salle M (Bozar) Quality of care [Standard presentation] Moderator : Pierre Bouzat (Grenoble, France) Moderator : Javier Fernandez (Barcelona , Spain) 13:45 - 14:00 - Noise in the ICUMark Dunn (Edinburgh, United Kingdom)

14:00 - 14:15 - We need multidisciplinary reviewIvor Douglas (Denver, United States)

14:15 - 14:30 - Good quality of care can reduce burnout in ICU doctorsOlusegun Olusanya (London, United Kingdom)

14:30 - 14:45 - Application of behavioral economics and serious game technologyDerek C Angus (Pittsburgh , United States)

14:45 - 15:00 - Using patient and family experience to improve critical careStephen Brett (London , United Kingdom)

15:00 - 15:15 - Discussion

How I see the future [Standard presentation] Moderator : Samir Jaber (Montpellier, France) Moderator : Can Ince (Amsterdam , Netherlands) 15:15 - 15:30 - The study of the microbiome will change the world Paul Wischmeyer (Durham, United States)

15:30 - 15:45 - Phenotyping will be everything Derek C Angus (Pittsburgh , United States)

15:45 - 16:00 - What precision medicine will look likeBenjamin Tang (Sydney, Australia)

16:00 - 16:15 - Autonomous systems and predictive analyticsMaxime Cannesson (Los Angeles, United States)

16:15 - 16:30 - Automated vasopressor therapyAlexandre Joosten (Le Kremlin-Bicêtre, France)

16:30 - 16:45 - Discussion

16:45 - 17:00 - ... but do not forget the Boeing 737 Max disastersAzriel Perel (Tel Aviv , Israel)

17:00 - 17:15 - Telemedicine will be everywhereCraig M Coopersmith (Atlanta, United States)

17:15 - 17:30 - Telemedicine in your ICUGernot Marx (Aachen , Germany)

17:30 - 17:45 - How social media will change our worldOlusegun Olusanya (London, United Kingdom)

17:45 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Tent How I´ll use my smartphone in the future [Standard presentation] Moderator : Vincent Liu (Oakland, United States) Moderator : Olusegun Olusanya (London, United Kingdom) 11:00 - 11:15 - For physiologic monitoring?Frédéric Michard (Lausanne, Switzerland)

11:15 - 11:30 - For hemodynamic monitoring?Bernd Saugel (Hamburg, Germany)

11:30 - 11:45 - Smartphones for medical educationAdrian Wong (Guilford, United Kingdom)

11:45 - 12:00 - Laypeople can use it before cardiac arrestLionel Lamhaut (Paris, France)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : Tent Hemodynamic monitoring [Standard presentation] Moderator : Fabio Guarracino (Pisa, Italy) Moderator : Michael Sander (Giessen, Germany) 13:45 - 14:00 - Is radial artery pressure monitoring reliable?André Denault (Montreal, Canada)

14:00 - 14:15 - We should better evaluate the cutaneous perfusion Jacques Creteur (Brussels , Belgium)

14:15 - 14:30 - Integrating the different variablesJean-Louis Teboul (Le Kremlin-Bicêtre, France)

14:30 - 14:45 - We need a dynamic evaluation of the different variablesOlivier Huet (Brest, France)

14:45 - 15:00 - Left ventricular contractility on assessment by echo: not just LVEFAnthony McLean (Sydney , Australia)

15:00 - 15:15 - Discussion

15:15 - 15:30 - Cerebral oximetry can help to assess the systemic circulation Matthias Heringlake (Lübeck , Germany)

15:30 - 15:45 - How I choose the optimal method for the individual patientBernd Saugel (Hamburg, Germany)

15:45 - 16:00 - Echocardiography is the best hemodynamic monitoring deviceAntoine Vieillard–Baron (Boulogne-Billancourt, France)

16:00 - 16:15 - No monitoring system has been shown to improve outcomeXavier Monnet (Le Kremlin-Bicêtre , France)

16:15 - 16:25 - Discussion

Corticosteroids in sepsis: for whom? [Standard presentation] Moderator : Jacques Duranteau (Le Kremlin-Bicêtre , France) Moderator : Laurence Busse (Atlanta, United States) 16:25 - 16:40 - A new look at HPA axis responsesGreet Van den Berghe (Leuven , Belgium)

16:40 - 16:55 - Let us measure cortisol, aldosterone and vitamin C levelsJeremy Cohen (Brisbane, Australia)

16:55 - 17:10 - Genetic variants affecting corticosteroid resistanceDjillali Annane (Garches , France)

17:10 - 17:20 - Discussion

17:20 - 17:35 - Machine learning will helpMichael Bauer (Jena , Germany)

17:35 - 17:50 - Non-corticosteroid options?Pieter Van Paassen (Maastricht, Netherlands)

17:50 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Silver Hall Back to bicarbonate administration? [Standard presentation] Moderator : Paolo Angeli (Padua, Italy) Moderator : Manuel Praga (Madrid, Spain) 11:00 - 11:15 - Why the question is raisedSamir Jaber (Montpellier, France)

11:15 - 11:30 - In renal failure?Lui Forni (Guildford, United Kingdom)

11:30 - 11:45 - In hypercapnic acidosis?Luciano Gattinoni (Göttingen, Germany)

11:45 - 12:00 - In CPR?Lars Wiuff Andersen (Aarhus, Denmark)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : Silver Hall RRT: practical aspects [Standard presentation] Moderator : Claudio Ronco (Vicenza, Italy) Moderator : Steffen R. Mitzner (Rostock , Germany) 13:45 - 14:00 - We can often waitStephane Gaudry (Colombes, France)

14:00 - 14:15 - No, we can´tRavindra Mehta (La Jolla, United States)

14:15 - 14:30 - I’ll tell you what I doLui Forni (Guildford, United Kingdom)

14:30 - 14:45 - Optimal anticoagulationLionel Velly (Marseille , France)

14:45 - 15:00 - Regional citrate anticoagulationManish Kaushik (Singapore, Singapore)

15:00 - 15:15 - Discussion

15:15 - 15:30 - Micronutrient supplementationMarlies Ostermann (London , United Kingdom)

15:30 - 15:45 - When to use hybrid techniquesEric Hoste (Ghent , Belgium)

15:45 - 16:00 - How to insert a ECCO2R systemPatrick Honoré (Brussels, Belgium)

16:00 - 16:15 - Therapeutic plasma exchange: you can do it yourselfElie Azoulay (Paris , France)

16:15 - 16:30 - Why and how to implement a team strategyCarole Ichai (Nice, France)

16:30 - 16:45 - Discussion

Acute liver failure [Tutorial] 16:45 - 17:15 - Acute liver failurePaolo Angeli (Padua, Italy)

The future of mechanical ventilators (with participation of the industry) [Round table] Moderator : Giacomo Bellani (Monza, Italy) 17:20 - 18:00 - The future of mechanical ventilators (with participation of the industry)Jeremy Beitler (New York, United States), Niall Ferguson (Toronto , Canada), Diederik Gommers (Rotterdam,Netherlands), Jean-Christophe Richard (Angers, France), Fernando Suarez Sipmann (Uppsala, Sweden)

Tuesday 15 September 2020 - AM

ROOM : 100 Hall Preparing for the next catastrophe [Standard presentation] Moderator : Jonathan Bannard–Smith (Manchester, United Kingdom) Moderator : Grant Bochicchio (St Louis, United States) 11:00 - 11:15 - Prepare your teamHeatherlee Bailey (Durham, United States)

11:15 - 11:30 - How to train for disaster medicineLionel Lamhaut (Paris, France)

11:30 - 11:45 - How to run a mass casualty response after the EDMichael Reade (Brisbane, Australia)

11:45 - 12:00 - How to prepare the aftermathCarole Ichai (Nice, France)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : 100 Hall After discharge from the ICU [Standard presentation] Moderator : Heatherlee Bailey (Durham, United States) Moderator : Michel Slama (Amiens , France) 13:45 - 14:00 - Chronic critical illnessCatherine L Hough (Seattle, United States)

14:00 - 14:15 - What affects ICU outcomes around the worldIgnacio Martin-Loeches (Dublin , Ireland)

14:15 - 14:30 - Risk of long-term mortality in sepsis survivorsManu Shankar–Hari (London, United Kingdom)

14:30 - 14:45 - Goal-directed therapy paradigmMark Mikkelsen (Philadelphia, United States)

14:45 - 14:55 - Discussion

14:55 - 15:10 - Enhancing recovery after sepsisHallie Prescott (Ann Arbor, United States)

15:10 - 15:25 - Long-term pain is often neglectedStephen Brett (London , United Kingdom)

15:25 - 15:40 - Post-ICU nutrition intakeArthur van Zanten (Ede, Netherlands)

15:40 - 15:55 - We need post-ICU activitiesMark Mikkelsen (Philadelphia, United States)

15:55 - 16:05 - Discussion

16:05 - 16:20 - Post-ICU dementia is commonE Wesley Ely (Nashville, United States)

16:20 - 16:35 - Long-term legacy of critical illness: what are the mechanisms?Greet Van den Berghe (Leuven , Belgium)

16:35 - 16:50 - ICU follow-up clinics: time for a new paradigm?Yasmine Ali Abdelhamid (Victoria, Australia)

16:50 - 17:05 - How to set up an ICU follow-up clinicJean-Charles Preiser (Brussels , Belgium)

17:05 - 17:20 - Discussion

My questions about COVID-19 epidemic [Round table] 17:20 - 18:00 - My questions about COVID-19 epidemic

Tuesday 15 September 2020 - AM

ROOM : Terarken (BOZAR) It is all in the microcirculation [Standard presentation] Moderator : Jean-Louis Teboul (Le Kremlin-Bicêtre, France) Moderator : Maxime Cannesson (Los Angeles, United States) 11:00 - 11:15 - How to preserve the endothelial glycocalyx?Michael Reade (Brisbane, Australia)

11:15 - 11:30 - Five reasons why I love the microcirculationJacques Duranteau (Le Kremlin-Bicêtre , France)

11:30 - 11:45 - A new target to improve outcome in sepsis?Jakob Stensballe (Copenhagen, Denmark)

11:45 - 12:00 - The new target: tissue red blood cell perfusion?Can Ince (Amsterdam , Netherlands)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : Terarken (BOZAR) Extracorporeal CO2 removal (ECCO2R) [Standard presentation] Moderator : Antonio Pesenti (Milan , Italy) Moderator : Maximilian Malfertheiner (Regensburg, Germany) 13:45 - 14:00 - In ARDS: yesAlain Combes (Paris , France)

14:00 - 14:15 - In ARDS: noGiacomo Bellani (Monza, Italy)

14:15 - 14:30 - In ARDS: only in some patients Daniel Brodie (New York, United States)

14:30 - 14:40 - Discussion

14:40 - 14:55 - It could facilitate spontaneous breathing in ARDSEddy Fan (Toronto, Canada)

14:55 - 15:10 - ECCO2R in decompensated COPDV Marco Ranieri (Bologna, Italy)

15:10 - 15:25 - Is there a CO2 reserve?Luciano Gattinoni (Göttingen, Germany)

15:25 - 15:35 - Discussion

15:35 - 15:50 - CO2 could also be eliminated by hemodialysis without bicarbonateJohn Kellum (Pittsburgh, United States)

15:50 - 16:05 - In the end, who could benefit from ECCO2R?Ewan Goligher (Toronto, Canada)

16:05 - 16:15 - Discussion

We do not need central venous catheters in ICU patients [Pro-con debate] Moderator : Dwight Bailey (Charlotte, United States) 16:20 - 16:50 - We do not need central venous catheters in ICU patients CON Daniel De Backer (Brussels, Belgium) PRO Paul H Mayo (New Hyde Park, United States)

I like the concept of phenotypes [Pro-con debate] Moderator : Jean-Daniel Chiche (Paris , France) 16:55 - 17:25 - I like the concept of phenotypes PRO Carolyn S Calfee (San Francisco , United States) CON Luciano Gattinoni (Göttingen, Germany)

ARDS: we should abandon neuromuscular blockade [Pro-con debate] Moderator : Alain Combes (Paris , France) 17:30 - 18:00 - ARDS: we should abandon neuromuscular blockade PRO Derek C Angus (Pittsburgh , United States) CON Laurent Papazian (Marseille , France)

Tuesday 15 September 2020 - AM

ROOM : 400 Hall Cardiac assistance [Standard presentation] Moderator : Jean-Daniel Chiche (Paris , France) Moderator : Olivier Huet (Brest, France) 11:00 - 11:15 - Cardiac assist devicesLudhmila Hajjar (Sao Paulo, Brazil)

11:15 - 11:30 - VA-ECMO in cardiogenic shockAlain Combes (Paris , France)

11:30 - 11:45 - Weaning from cardiac support: focusing on the heartFabio Guarracino (Pisa, Italy)

11:45 - 12:00 - ...and/or on the microcirculationJan Bakker (New York, United States)

12:00 - 12:15 - Discussion

Tuesday 15 September 2020 - PM

ROOM : 400 Hall Feeding [Standard presentation] Moderator : Jeremy Cohen (Brisbane, Australia) Moderator : Jonathan Bannard–Smith (Manchester, United Kingdom) 13:45 - 14:00 - How to achieve a high protein targetArthur van Zanten (Ede, Netherlands)

14:00 - 14:15 - Balancing energy and protein intake in the acute phasePierre Singer (Petah Tikva , Israel)

14:15 - 14:30 - Early parenteral nutrition harms undernourished and also young childrenGreet Van den Berghe (Leuven , Belgium)

14:30 - 14:40 - Discussion

14:40 - 14:55 - Effects of crystalloids and colloids on enteral nutrition toleranceDjillali Annane (Garches , France)

14:55 - 15:10 - Should enteral nutrition be continuous or intermittent?Michaël Casaer (Leuven, Belgium)

15:10 - 15:25 - How to stimulate the patient’s appetiteJean-Charles Preiser (Brussels , Belgium)

15:25 - 15:40 - Reflux events in relation with proceduresYaron Bar–Lavie (Haifa, Israel)

15:40 - 15:55 - Compensation management in enteral feedingElisabeth De Waele (Brussels, Belgium)

15:55 - 16:05 - Discussion

Vitamins for everyone [Standard presentation] Moderator : Pierre Singer (Petah Tikva , Israel) Moderator : Elisabeth De Waele (Brussels, Belgium) 16:05 - 16:20 - How to assess vitamin C status and oxidative stress at the bedsideHeleen Oudemans-Van Straaten (Amsterdam , Netherlands)

16:20 - 16:35 - Combination vitamin cocktail for sepsis: in search of the magic elixirStephen M Pastores (New York, United States)

16:35 - 16:50 - Only in sepsis?Greg Martin (Atlanta, United States)

16:50 - 17:00 - Discussion

17:00 - 17:15 - When to give vitamin DMichaël Casaer (Leuven, Belgium)

17:15 - 17:30 - Vitamin D in respiratory failureDaniel Talmor (Boston , United States)

17:30 - 17:45 - Do not forget thiamineMichael W Donnino (Boston, United States)

17:45 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Panoramic Hall How to manage vasopressor agents in sepsis RT? [Round table] Moderator : Anthony Gordon (London , United Kingdom) 11:00 - 11:35 - How to manage vasopressor agents in sepsis ?Jan Bakker (New York, United States), Maurizio Cecconi (Rozzano, MI, Italy), Christopher Seymour (Pittsburgh,United States), Frank van Haren (Canberra, Australia)

ARDS: do we need the syndrome? [Round table] Moderator : Michael A Matthay (San Francisco, United States) 11:40 - 12:15 - ARDS: do we need the syndrome?Niall Ferguson (Toronto , Canada), Antonio Pesenti (Milan , Italy), Elisabeth Riviello (Boston, UnitedStates), Lorraine B Ware (Nashville , United States)

Tuesday 15 September 2020 - PM

ROOM : Panoramic Hall Coagulopathies [Standard presentation] Moderator : Manuel Praga (Madrid, Spain) Moderator : Michael Reade (Brisbane, Australia) 13:45 - 14:00 - DIC: higher risk of bleeding or of thrombosis?Nicole Juffermans (Amsterdam , Netherlands)

14:00 - 14:15 - Sepsis-associated coagulopathyTom van der Poll (Amsterdam , Netherlands)

14:15 - 14:30 - Trauma-induced coagulopathyMarc Maegele (Cologne , Germany)

14:30 - 14:40 - Discussion

14:40 - 14:55 - Management of patients under DOACsJerrold H Levy (Durham, United States)

14:55 - 15:10 - Treatment of perioperative bleedingVladimir Cerny (Usti nad Labem, Czech Republic)

15:10 - 15:25 - New coagulopathies in critical careBeverley Hunt (London , United Kingdom)

15:25 - 15:35 - Discussion

E-cigarettes for the intensivist [Plenary lecture] 15:40 - 16:00 - E-cigarettes for the intensivistCarolyn S Calfee (San Francisco , United States)

Precision medicine in traumatic brain injury [Plenary lecture] 16:05 - 16:25 - Precision medicine in traumatic brain injuryDavid Menon (Cambridge , United Kingdom)

Hematological challenges [Standard presentation] Moderator : Jakob Stensballe (Copenhagen, Denmark) Moderator : Tom van der Poll (Amsterdam , Netherlands) 16:30 - 16:45 - Why is the septic patient often anemic?Manu Shankar–Hari (London, United Kingdom)

16:45 - 17:00 - Facing thrombocytopenia of unclear etiologyManuel Praga (Madrid, Spain)

17:00 - 17:15 - Thrombotic microangiopathies: TTP and HUSElie Azoulay (Paris , France)

17:15 - 17:30 - Macrophage activation syndrome Evangelos Giamarellos–Bourboulis (Athens, Greece)

17:30 - 17:45 - Mechanical thromboprophylaxis in critical careBeverley Hunt (London , United Kingdom)

17:45 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : Studio Room Challenging cases [Case discussion] Moderator : Michael W Donnino (Boston, United States) 11:00 - 11:35 - Challenging casesCraig M Coopersmith (Atlanta, United States), Diederik Gommers (Rotterdam, Netherlands), John J Marini (StPaul, United States), Laurent Papazian (Marseille , France)

How to manage a patient with severe brain trauma? [Round table] Moderator : Victoria McCredie (Toronto, Canada) 11:40 - 12:15 - How to manage a patient with severe brain trauma?Pierre Bouzat (Grenoble, France), Peter Le Roux (Wynnewood, United States), Chiara Robba (Genova,Italy), Nino Stocchetti (Milan , Italy), David Menon (Cambridge , United Kingdom)

Tuesday 15 September 2020 - PM

ROOM : Studio Room Big data, machine learning and artificial intelligence [Standard presentation] Moderator : Anthony Gordon (London , United Kingdom) Moderator : Alexandre Mebazaa (Paris , France) 13:30 - 13:45 - Implementation science for ICU informaticsPhilip Hopkins (London, United Kingdom)

13:45 - 14:00 - We can start with cohort studiesNuala Meyer (Wynnewood, United States)

14:00 - 14:15 - How we can use electronic health recordsVincent Liu (Oakland, United States)

14:15 - 14:30 - Discussion

14:30 - 14:45 - Machine learning in the ICUMaurizio Cecconi (Rozzano, MI, Italy)

14:45 - 15:00 - How AI can replace the ICU doctorAldo Faisal (London, United Kingdom)

15:00 - 15:15 - The dark side of all thisMaxime Cannesson (Los Angeles, United States)

15:15 - 15:30 - Discussion

15:30 - 15:45 - Break

Severe ARDS: should I paralyse? [Standard presentation] Moderator : Rémi Coudroy (Poitiers, France) Moderator : Pierre–François Laterre (Brussels , Belgium) 15:45 - 16:00 - What we learned from the Petal ROSE studyB Taylor Thompson (Boston , United States)

16:00 - 16:15 - How the Petal ROSE trial differs from my earlier studyLaurent Papazian (Marseille , France)

16:15 - 16:30 - Ventilator asynchrony: recognition and managementNuala Meyer (Wynnewood, United States)

16:30 - 16:45 - Like BiRDS... breathing spontaneously from the startJean-Christophe Richard (Angers, France)

16:45 - 17:00 - Discussion

17:00 - 17:15 - What about lung protective sedation?Elias N Baedorf Kassis (Boston, United States)

17:15 - 17:30 - Partial paralysis may be an answerLeo Heunks (Amsterdam, Netherlands)

17:30 - 17:45 - How artificial intelligence can helpGuillermo Gutierrez (Washington, United States)

17:45 - 18:00 - Discussion

Tuesday 15 September 2020 - AM

ROOM : 300 Hall

Tuesday 15 September 2020 - AM

ROOM : Arc Room

Tuesday 15 September 2020 - AM

ROOM : Corner B (Exhibition Area)

Tuesday 15 September 2020 - PM

ROOM : Corner B (Exhibition Area) Complications of new cancer therapies [Meet the experts] 14:00 - 14:30 - Complications of new cancer therapiesElie Azoulay (Paris , France), Stephen M Pastores (New York, United States)

Tuesday 15 September 2020 - AM

ROOM : Lung House (Exhibition Area)

Tuesday 15 September 2020 - AM

ROOM : Neuro-Lab (Exhibition Area)

Wednesday 16 September 2020 - AM

ROOM : HLB Room

Wednesday 16 September 2020 - AM

ROOM : Gold Hall Pathophysiology of MODS revisited [Standard presentation] Moderator : Greg Martin (Atlanta, United States) Moderator : Beverley Hunt (London , United Kingdom) 8:00 - 8:15 - How do the organs deteriorate?Michael Bauer (Jena , Germany)

8:15 - 8:30 - How do cells die?Can Ince (Amsterdam , Netherlands)

8:30 - 8:45 - Role of the gastrointestinal tract revisitedJohn C Marshall (Toronto , Canada)

8:45 - 9:00 - Role of mechanical ventilationV Marco Ranieri (Bologna, Italy)

9:00 - 9:10 - Discussion

9:10 - 9:25 - Oxidative stress, cell death and inflammationSally Wenzel (Pittsburgh, United States)

9:25 - 9:40 - Extracellular vesicles are key mediatorsMichael A Matthay (San Francisco, United States)

9:40 - 9:55 - How cell-free hemoglobin can mediate organ dysfunctionLorraine B Ware (Nashville , United States)

9:55 - 10:10 - Platelets play an important roleB Taylor Thompson (Boston , United States)

10:10 - 10:25 - Discussion

10:25 - 10:40 - Break

… in the era of personalized medicine [Standard presentation] Moderator : Markus Skrifvars (Helsinki, Finland) Moderator : Stephen Brett (London , United Kingdom) 10:40 - 10:55 - Precision critical care: current barriers, future possibilitiesCarolyn S Calfee (San Francisco , United States)

10:55 - 11:10 - How we can address the heterogeneity of treatment effectDerek C Angus (Pittsburgh , United States)

11:10 - 11:20 - Discussion

11:20 - 11:35 - Which markers matter?Nuala Meyer (Wynnewood, United States)

11:35 - 11:50 - Lung-protective ventilation Antonio Pesenti (Milan , Italy)

11:50 - 12:05 - ACE deficiencies to guide vasopressor therapiesLaurence Busse (Atlanta, United States)

12:05 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : Gold Hall Vasoplegia [Standard presentation] Moderator : Jean-Louis Teboul (Le Kremlin-Bicêtre, France) Moderator : Azriel Perel (Tel Aviv , Israel) 13:45 - 14:00 - Reducing unnecessary volume resuscitationPaul H Mayo (New Hyde Park, United States)

14:00 - 14:15 - Do vasopressors really lead to limb loss in sepsis?Christopher Seymour (Pittsburgh, United States)

14:15 - 14:30 - Variability in vasopressor prescriptionsHannah Wunsch (Toronto, Canada)

14:30 - 14:45 - Alternatives to norepinephrineAnthony Gordon (London , United Kingdom)

14:45 - 15:00 - Discussion

15:00 - 15:15 - When to use vasopressinLudhmila Hajjar (Sao Paulo, Brazil)

15:15 - 15:30 - When to use angiotensin IIDwight Bailey (Charlotte, United States)

15:30 - 15:45 - Personalized blood pressure targetsFrank van Haren (Canberra, Australia)

15:45 - 16:00 - Hypertension during recovery: is it a problem?Stephane Gaudry (Colombes, France)

16:00 - 16:15 - Discussion

How I individualize nutrition in the ICU [Round table] Moderator : Heleen Oudemans-Van Straaten (Amsterdam , Netherlands) 16:15 - 16:50 - How I individualize nutrition in the ICUMichaël Casaer (Leuven, Belgium), Carole Ichai (Nice, France), Arthur van Zanten (Ede, Netherlands), PierreSinger (Petah Tikva , Israel), Elisabeth De Waele (Brussels, Belgium)

New antiviral agents [Tutorial] 16:55 - 17:20 - New antiviral agentsTobias Welte (Hannover , Germany)

How to manage the ECMO patient [Round table] Moderator : Eddy Fan (Toronto, Canada) 17:25 - 18:00 - How to manage the ECMO patientDaniel Brodie (New York, United States), Alain Combes (Paris , France), Luciano Gattinoni (Göttingen,Germany), Maximilian Malfertheiner (Regensburg, Germany)

Wednesday 16 September 2020 - AM

ROOM : Copper Hall Practical aspects of CPR [Standard presentation] Moderator : Daryl Jones (Heidelberg, Australia) Moderator : Jean-Christophe Richard (Angers, France) 8:00 - 8:15 - Airway managementJerry Nolan (Bath, United Kingdom)

8:15 - 8:30 - Optimal chest compression revisitedPaul E Pepe (Dallas , United States)

8:30 - 8:45 - Monitoring the quality of CPRClaudio Sandroni (Rome , Italy)

8:45 - 9:00 - Discussion

9:00 - 9:15 - The role of end-tidal CO2 in decision makingLaurie Morrison (Toronto , Canada)

9:15 - 9:30 - The pros and cons of epinephrineKatherine Berg (Boston, United States)

9:30 - 9:45 - Antiarrhythmic drugsGavin Perkins (Warwick, United Kingdom)

9:45 - 10:00 - Discussion

10:00 - 10:15 - … and the rest: vasopressin, corticosteroids, magnesium, calcium?Lars Wiuff Andersen (Aarhus, Denmark)

10:15 - 10:30 - What is “refractory cardiac arrest”?Claudio Sandroni (Rome , Italy)

10:30 - 10:45 - Should we use ECPR?Lionel Lamhaut (Paris, France)

10:45 - 11:00 - What is on the horizon?Paul E Pepe (Dallas , United States)

11:00 - 11:15 - Discussion

11:15 - 11:30 - Break

VILI: what are the most important variables to target? [Round table] Moderator : Niall Ferguson (Toronto , Canada) 11:30 - 12:15 - VILI: what are the most important variables to target?Marcelo Amato (Sao Paulo , Brazil), Luciano Gattinoni (Göttingen, Germany), Leo Heunks (Amsterdam,Netherlands), John J Marini (St Paul, United States)

Wednesday 16 September 2020 - PM

ROOM : Copper Hall Towards precision in ARDS [Standard presentation] Moderator : V Marco Ranieri (Bologna, Italy) Moderator : Timothy Walsh (Edinburgh , United Kingdom) 13:45 - 14:00 - Do we need the acronym ARDS?Niall Ferguson (Toronto , Canada)

14:00 - 14:15 - The challenge of hematological malignanciesElie Azoulay (Paris , France)

14:15 - 14:30 - The challenge of systemic diseasesJean-Daniel Chiche (Paris , France)

14:30 - 14:45 - Discussion

14:45 - 15:00 - The challenge of interstitial lung diseaseStephane Gaudry (Colombes, France)

15:00 - 15:15 - Corticosteroids for whom?Stephen M Pastores (New York, United States)

15:15 - 15:30 - Phenotypes: how to bring precision medicine to the bedsideCarolyn S Calfee (San Francisco , United States)

15:30 - 15:45 - Discussion

15:45 - 16:00 - Are phenotypes myths or useful tools?Manu Shankar–Hari (London, United Kingdom)

16:00 - 16:15 - Let us look at heterogeneity in clinical and biological variablesMichael A Matthay (San Francisco, United States)

16:15 - 16:30 - Separation according to responses to therapeutic interventionsNuala Meyer (Wynnewood, United States)

16:30 - 16:45 - Discussion

Atypical renal failure [Case discussion] Moderator : Manuel Praga (Madrid, Spain) 16:50 - 17:25 - Atypical renal failureElie Azoulay (Paris , France), Pieter Van Paassen (Maastricht, Netherlands), Victoria Metaxa (London, UnitedKingdom), Beverley Hunt (London , United Kingdom)

The Bayesian intensivist: reconciling evidence, experience, and common sense [Plenary lecture] 17:30 - 18:00 - The Bayesian intensivist: reconciling evidence, experience, and common senseJohn C Marshall (Toronto , Canada)

Wednesday 16 September 2020 - AM

ROOM : Salle M (Bozar) The year in review [Standard presentation] Moderator : Olusegun Olusanya (London, United Kingdom) Moderator : Yaron Bar–Lavie (Haifa, Israel) 8:00 - 8:15 - ICU-acquired weaknessXavier Wittebole (Brussels, Belgium)

8:15 - 8:30 - Cardiac arrestGavin Perkins (Warwick, United Kingdom)

8:30 - 8:45 - Acute cardiologyAlexandre Mebazaa (Paris , France)

8:45 - 9:00 - Acute renal failureRavindra Mehta (La Jolla, United States)

9:00 - 9:15 - Discussion

Acute renal failure [Standard presentation] Moderator : Jay Koyner (Chicago, United States) Moderator : Manish Kaushik (Singapore, Singapore) 9:15 - 9:30 - In septic patientsTom van der Poll (Amsterdam , Netherlands)

9:30 - 9:45 - Renal cytokine releaseMarlies Ostermann (London , United Kingdom)

9:45 - 10:00 - Lung-kidney crosstalk in VILIV Marco Ranieri (Bologna, Italy)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Contrast-induced renal failure: new insightClaudio Ronco (Vicenza, Italy)

10:30 - 10:45 - New findings in hepatorenal syndromePaolo Angeli (Padua, Italy)

10:45 - 11:00 - Assessing venous congestion by ultrasound can helpAndré Denault (Montreal, Canada)

11:00 - 11:15 - Discussion

11:15 - 11:30 - Let us look at the microcirculationJacques Duranteau (Le Kremlin-Bicêtre , France)

11:30 - 11:45 - When to consider a thrombotic microangiopathyManuel Praga (Madrid, Spain)

11:45 - 12:00 - Renal recovery patternsRavindra Mehta (La Jolla, United States)

12:00 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : Salle M (Bozar) ECMO for respiratory failure [Standard presentation] Moderator : Roberto Lorusso (Maastricht, Netherlands) Moderator : Daniel Talmor (Boston , United States) 13:45 - 14:00 - Rescue vs. salvage therapies: what is the difference?Daniel Brodie (New York, United States)

14:00 - 14:15 - ECMO or prone positioning?Laurent Papazian (Marseille , France)

14:15 - 14:30 - What, not both?Alain Combes (Paris , France)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Does high flow VV-ECMO make sense in ARDS?Luciano Gattinoni (Göttingen, Germany)

15:00 - 15:15 - Weaning from VV-ECMONiall Ferguson (Toronto , Canada)

15:15 - 15:30 - What can we learn from the ECMO trials performed to date?Michael Quintel (Göttingen , Germany)

15:30 - 15:45 - Discussion

15:45 - 15:55 - Break

Airway challenges [Standard presentation] Moderator : Lars Wiuff Andersen (Aarhus, Denmark) Moderator : Adrian Wong (Guilford, United Kingdom) 15:55 - 16:10 - Initial approach: high flow oxygen cannula or conventional oxygen?Elie Azoulay (Paris , France)

16:10 - 16:25 - Emergency airway managementWesley Self (Nashville, United States)

16:25 - 16:40 - When to use a videolaryngoscopePaolo Pelosi (Genoa , Italy)

16:40 - 16:55 - Preoxygenation and intubation in patients at riskSamir Jaber (Montpellier, France)

16:55 - 17:10 - We need combined team training for airway managementPaul H Mayo (New Hyde Park, United States)

17:10 - 17:25 - Discussion

The cirrhotic patient [Tutorial] 17:30 - 18:00 - The cirrhotic patientJavier Fernandez (Barcelona , Spain)

Wednesday 16 September 2020 - AM

ROOM : Tent Optimizing perioperative care [Standard presentation] Moderator : Marc Maegele (Cologne , Germany) Moderator : Samir Jaber (Montpellier, France) 8:00 - 8:15 - Strategies to prevent perioperative hypotensionMichael Sander (Giessen, Germany)

8:15 - 8:30 - Is there a magic blood pressure level?Alexandre Joosten (Le Kremlin-Bicêtre, France)

8:30 - 8:45 - We can predict hypotensionThomas Scheeren (Groningen, Netherlands)

8:45 - 9:00 - Optimal use of vasopressors and inotropesVladimir Cerny (Usti nad Labem, Czech Republic)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Perioperative goal-directed therapy: basic concepts and future directionsBernd Saugel (Hamburg, Germany)

9:30 - 9:45 - How useful is monitoring the microcirculation?Jacques Duranteau (Le Kremlin-Bicêtre , France)

9:45 - 10:00 - Nutritional managementPaul Wischmeyer (Durham, United States)

10:00 - 10:15 - Critical care for postoperative patients with end-stage liver diseaseMichael Bauer (Jena , Germany)

10:15 - 10:30 - Discussion

10:30 - 10:40 - Break

Update on hyperglycemia [Standard presentation] Moderator : Greet Van den Berghe (Leuven , Belgium) Moderator : Erwan L'Her (Brest, France) 10:40 - 10:55 - Time-in-range in glucose managementGrant Bochicchio (St Louis, United States)

10:55 - 11:10 - Novelties in oral antidiabetic drugsJean-Charles Preiser (Brussels , Belgium)

11:10 - 11:20 - Discussion

11:20 - 11:35 - Diabetic ketoacidosis: structured care pathwayIvor Douglas (Denver, United States)

11:35 - 11:50 - Moving closer to personalized glycemic controlJames Krinsley (Stamford , United States)

11:50 - 12:05 - Should survivors of stress hyperglycemia be screened for diabetes?Yasmine Ali Abdelhamid (Victoria, Australia)

12:05 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : Tent Clinical (mis)diagnosis of sepsis [Case discussion] Moderator : Mervyn Singer (London, United Kingdom) 13:45 - 14:25 - Clinical (mis)diagnosis of sepsisMaurizio Cecconi (Rozzano, MI, Italy), Andrea Kwa (Singapore, Singapore), Massimo Antonelli (Rome,Italy), E Wesley Ely (Nashville, United States)

14:30 - 14:45 - Break

Traumatic brain injury: initial management [Standard presentation] Moderator : Romain Sonneville (Paris, France) Moderator : Laurie Morrison (Toronto , Canada) 14:45 - 15:00 - New conceptsPierre Bouzat (Grenoble, France)

15:00 - 15:15 - Should we give tranexamic acid?Nicole Juffermans (Amsterdam , Netherlands)

15:15 - 15:30 - Any place for pharmacological therapies?Andrea Lavinio (Cambridge , United Kingdom)

15:30 - 15:45 - How to limit secondary brain injuryChiara Robba (Genova, Italy)

15:45 - 16:00 - Discussion

16:00 - 16:15 - Optimal use of vasopressorsFabio S. Taccone (Brussels , Belgium)

16:15 - 16:30 - Optimal PaO2 and PaCO2 targetsMauro Oddo (Lausanne , Switzerland)

16:30 - 16:45 - Extracranial complicationsGiuseppe Citerio (Monza, Italy)

16:45 - 17:00 - Discussion

17:00 - 17:15 - In the elderly patientPierre Bouzat (Grenoble, France)

17:15 - 17:30 - Are biomarkers of any use?Michael Reade (Brisbane, Australia)

17:30 - 17:45 - Do not forget cases of moderate severity Nino Stocchetti (Milan , Italy)

17:45 - 18:00 - Discussion

Wednesday 16 September 2020 - AM

ROOM : Silver Hall Fungal infections [Standard presentation] Moderator : Michael S Niederman (New York, United States) Moderator : Massimo Antonelli (Rome, Italy) 8:00 - 8:15 - Biomarkers for fungal infections: what, when and how?Thierry Calandra (Lausanne , Switzerland)

8:15 - 8:30 - Empirical therapy for Candida in critically ill patientsJean–François Timsit (Paris, France)

8:30 - 8:45 - Septic shock and invasive candidiasis: a devastating situation?Matteo Bassetti (Genova, Italy)

8:45 - 8:55 - Discussion

8:55 - 9:10 - Invasive infections in immunocompetent patientsPeter Pickkers (Nijmegen, Netherlands)

9:10 - 9:25 - Invasive infections in immunocompromised patientsElie Azoulay (Paris , France)

9:25 - 9:40 - Candida auris: the new yeast threatThierry Calandra (Lausanne , Switzerland)

9:40 - 9:50 - Discussion

Severe CAP, HAP and VAP [Standard presentation] Moderator : Laurent Papazian (Marseille , France) Moderator : Stephen M Pastores (New York, United States) 9:50 - 10:05 - Host responseTom van der Poll (Amsterdam , Netherlands)

10:05 - 10:20 - Defense mechanisms revisitedMichael A Matthay (San Francisco, United States)

10:20 - 10:35 - There is a continuum in respiratory infectionsIgnacio Martin-Loeches (Dublin , Ireland)

10:35 - 10:50 - Does subglottic colonization predict VAP?Massimo Antonelli (Rome, Italy)

10:50 - 11:05 - Novel antibiotic therapiesMatteo Bassetti (Genova, Italy)

11:05 - 11:20 - Discussion

11:20 - 11:35 - Should all patients get adjunctive macrolide therapy?Michael S Niederman (New York, United States)

11:35 - 11:50 - Should all patients get corticosteroids?Djillali Annane (Garches , France)

11:50 - 12:05 - Can we eradicate VAP?Michael S Niederman (New York, United States)

12:05 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : Silver Hall The immune response [Standard presentation] Moderator : David Grimaldi (Brussels, Belgium) Moderator : Jean–François Timsit (Paris, France) 13:40 - 13:55 - Single-cell technology to explore the immune systemThierry Calandra (Lausanne , Switzerland)

13:55 - 14:10 - Biomarkers of immune hypoactivationIvor Douglas (Denver, United States)

14:10 - 14:25 - Biomarkers of acquired immunosuppressionThomas Rimmelé (Lyon, France)

14:25 - 14:40 - How our current therapies influence immunityPeter Radermacher (Ulm , Germany)

14:40 - 14:55 - Norepinephrine has immunosuppressive effectsPeter Pickkers (Nijmegen, Netherlands)

14:55 - 15:10 - The adaptive immune system as a therapeutic target?Manu Shankar–Hari (London, United Kingdom)

15:10 - 15:25 - How new strategies could be based on immune monitoringMassimo Girardis (Modena , Italy)

Sepsis: a personalized approach [Standard presentation] Moderator : Michael Bauer (Jena , Germany) Moderator : Philip Hopkins (London, United Kingdom) 15:25 - 15:40 - The sepsis hypothesis is simply wrongJohn C Marshall (Toronto , Canada)

15:40 - 15:55 - Subsetting human responsesBenjamin Tang (Sydney, Australia)

15:55 - 16:10 - Better characterization of hemodynamic profiles?Antoine Vieillard–Baron (Boulogne-Billancourt, France)

16:10 - 16:25 - Better characterisation of immunological profilesThomas Rimmelé (Lyon, France)

16:25 - 16:40 - Clinical phenotypesChristopher Seymour (Pittsburgh, United States)

16:40 - 16:55 - Genetic variants affecting corticosteroids resistance in sepsisDjillali Annane (Garches , France)

16:55 - 17:10 - Can renin measurements help?Lui Forni (Guildford, United Kingdom)

17:10 - 17:25 - Personalized immunoglobulin therapyAxel Nierhaus (Hamburg , Germany)

17:25 - 17:40 - A new model to enable precision medicine for sepsisHector R Wong (Cincinnati , United States)

17:40 - 17:55 - Well.... septic patients may not be all so different

Benjamin Tang (Sydney, Australia)

17:55 - 18:00 - Discussion

Wednesday 16 September 2020 - AM

ROOM : 100 Hall Why so many negative trials? [Standard presentation] Moderator : Anthony Gordon (London , United Kingdom) Moderator : Arthur van Zanten (Ede, Netherlands) 8:00 - 8:15 - Let us start with mouse models: what can be translated and what can´tCraig M Coopersmith (Atlanta, United States)

8:15 - 8:30 - Understanding trials at the bedside: role of process evaluationTimothy Walsh (Edinburgh , United Kingdom)

8:30 - 8:45 - Reversible or attributable or modifiable risk in sepsis?Manu Shankar–Hari (London, United Kingdom)

8:45 - 9:00 - Beware of design biasJeremy Beitler (New York, United States)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Heterogeneity in treatment effects is importantEwan Goligher (Toronto, Canada)

9:30 - 9:45 - Heterogeneity in treatment effects is not so importantManu Shankar–Hari (London, United Kingdom)

9:45 - 10:00 - How I would design the next clinical trialMichael W Donnino (Boston, United States)

10:00 - 10:10 - Discussion

Can I make my trial better [Standard presentation] Moderator : Guillermo Gutierrez (Washington, United States) Moderator : Ludhmila Hajjar (Sao Paulo, Brazil) 10:10 - 10:25 - Novel trial designs in sepsisDerek C Angus (Pittsburgh , United States)

10:25 - 10:40 - New composite endpoints for ARDSB Taylor Thompson (Boston , United States)

10:40 - 10:55 - Introduction to Bayesian analysesLars Wiuff Andersen (Aarhus, Denmark)

10:55 - 11:10 - Why adaptive designs are here to stayChristopher Seymour (Pittsburgh, United States)

11:10 - 11:20 - Discussion

11:20 - 11:35 - Platform trials can integrate research and quality improvementJohn C Marshall (Toronto , Canada)

11:35 - 11:50 - The involvement of patients in designing major interventional trialsAndrew Klein (Cambridge, United Kingdom)

11:50 - 12:05 - Big data analytics for hypothesis generating studiesIvor Douglas (Denver, United States)

12:05 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : 100 Hall Acute-on-chronic liver failure [Standard presentation] Moderator : Christian J Wiedermann (Innsbruck, Austria) Moderator : Sigismond Lasocki (Angers, France) 13:45 - 14:00 - What are we talking about?Javier Fernandez (Barcelona , Spain)

14:00 - 14:15 - New indication for use of albuminPaolo Angeli (Padua, Italy)

14:15 - 14:30 - Long-term albumin treatment?Paolo Caraceni (Bologna, Italy)

14:30 - 14:45 - Management of coagulopathyDietmar Fries (Innsbruck, Austria)

14:45 - 15:00 - The place for extracorporeal therapiesSteffen R. Mitzner (Rostock , Germany)

15:00 - 15:15 - How to diagnose sepsis in these patients?Pierre–François Laterre (Brussels , Belgium)

15:15 - 15:25 - Discussion

Massive bleeding [Standard presentation] Moderator : Jerrold H Levy (Durham, United States) Moderator : Vladimir Cerny (Usti nad Labem, Czech Republic) 15:25 - 15:40 - Tranexamic acid for everyoneBeverley Hunt (London , United Kingdom)

15:40 - 15:55 - Use of low-titer O+ bloodPaul E Pepe (Dallas , United States)

15:55 - 16:10 - Use of frozen plateletsNicole Juffermans (Amsterdam , Netherlands)

16:10 - 16:25 - Use of factor concentratesKeyvan Karkouti (Toronto, Canada)

16:25 - 16:40 - Use of fibrinogenMarc Maegele (Cologne , Germany)

16:40 - 16:50 - Discussion

16:50 - 17:05 - My point-of-care based algorithmKeyvan Karkouti (Toronto, Canada)

17:05 - 17:20 - Next generation resuscitation will target the endotheliumJakob Stensballe (Copenhagen, Denmark)

17:20 - 17:35 - After stopping the bleeding, resuscitate the microcirculationJacques Duranteau (Le Kremlin-Bicêtre , France)

17:35 - 17:50 - Does all this result in more thromboembolic complications?Nicole Juffermans (Amsterdam , Netherlands)

17:50 - 18:00 - Discussion

Wednesday 16 September 2020 - AM

ROOM : Terarken (BOZAR) Sepsis in particular settings [Standard presentation] Moderator : Eddy Fan (Toronto, Canada) Moderator : Jan Bakker (New York, United States) 8:00 - 8:15 - Hypothermic vs. febrile sepsisNicole Juffermans (Amsterdam , Netherlands)

8:15 - 8:30 - The cirrhotic patientPaolo Angeli (Padua, Italy)

8:30 - 8:45 - The hematology-oncology patientThierry Calandra (Lausanne , Switzerland)

8:45 - 9:00 - Discussion

9:00 - 9:15 - The alcoholic patient: molecular and cellular insightsCraig M Coopersmith (Atlanta, United States)

9:15 - 9:30 - The specificity of maternal sepsisHallie Prescott (Ann Arbor, United States)

9:30 - 9:45 - Discussion

9:45 - 10:00 - Break

Predicting major complications with artificial intelligence [Standard presentation] Moderator : Victoria McCredie (Toronto, Canada) Moderator : Hannah Wunsch (Toronto, Canada) 10:00 - 10:15 - Predictive modeling/machine learning in critical careVincent Liu (Oakland, United States)

10:15 - 10:30 - Predicting decompensationMichael R. Pinsky (Pittsburgh, United States)

10:30 - 10:45 - Predicting hypotensionMaxime Cannesson (Los Angeles, United States)

10:45 - 11:00 - Predicting sepsisJean-Daniel Chiche (Paris , France)

11:00 - 11:15 - Predicting mortality in sepsis Hector R Wong (Cincinnati , United States)

11:15 - 11:30 - Discussion

How I prognosticate after cardiac arrest [Round table] Moderator : Claudio Sandroni (Rome , Italy) 11:35 - 12:15 - How I prognosticate after cardiac arrest Clifton Callaway (Pittsburgh, United States), Mauro Oddo (Lausanne , Switzerland), Fabio S. Taccone (Brussels ,Belgium), Lionel Velly (Marseille , France)

Wednesday 16 September 2020 - PM

ROOM : Terarken (BOZAR) Challenges in research [Standard presentation] Moderator : Derek C Angus (Pittsburgh , United States) Moderator : Hallie Prescott (Ann Arbor, United States) 13:45 - 14:00 - How to start experimental researchPeter Radermacher (Ulm , Germany)

14:00 - 14:15 - How to start critical care researchLaurence Busse (Atlanta, United States)

14:15 - 14:30 - Pre-hospital trialsGavin Perkins (Warwick, United Kingdom)

14:30 - 14:45 - Research in low income countriesElisabeth Riviello (Boston, United States)

14:45 - 15:00 - Simple monitoring systems will facilitate global researchFrédéric Michard (Lausanne, Switzerland)

15:00 - 15:15 - Discussion

Use and abuse of inotropes [Standard presentation] Moderator : Bernd Saugel (Hamburg, Germany) Moderator : Matthias Heringlake (Lübeck , Germany) 15:15 - 15:30 - Are inotropic agents useful in septic shock? Anthony Gordon (London , United Kingdom)

15:30 - 15:45 - When I add an inotropic agentMassimo Girardis (Modena , Italy)

15:45 - 16:00 - When I avoid an inotropic agentFabio Guarracino (Pisa, Italy)

16:00 - 16:15 - Epinephrine is a dangerous substanceAlexandre Mebazaa (Paris , France)

16:15 - 16:30 - Discussion

16:30 - 16:45 - We could use more beta-blockersAnna Vachulova (Bratislava, Slovakia)

16:45 - 17:00 - What do I do with my patient´s beta-blocker?Christopher Seymour (Pittsburgh, United States)

17:00 - 17:15 - I also use VA-ECMO for severe cardiac dysfunction in septic shockAlain Combes (Paris , France)

17:15 - 17:30 - Discussion

We need to routinely monitor respiratory effort during ventilation [Pro-con debate] Moderator : Ignacio Martin-Loeches (Dublin , Ireland) 17:30 - 18:00 - We need to routinely monitor respiratory effort during ventilation CON Jeremy Beitler (New York, United States) PRO Ewan Goligher (Toronto, Canada)

Wednesday 16 September 2020 - AM

ROOM : 400 Hall Severe heart failure [Standard presentation] Moderator : Carlos Ferrando (Barcelona, Spain) Moderator : Fabio Guarracino (Pisa, Italy) 8:00 - 8:15 - Pathophysiologic basis for septic cardiomyopathyMichael R. Pinsky (Pittsburgh, United States)

8:15 - 8:30 - All reversible non-ischemic myocardial depression is not TakotsuboAnthony McLean (Sydney , Australia)

8:30 - 8:45 - Echo-Doppler is limited in the assessment of LV filling pressureMichel Slama (Amiens , France)

8:45 - 9:00 - Management of cardiogenic shockAntoine Herpain (Brussels, Belgium)

9:00 - 9:15 - Discussion

9:15 - 9:30 - How to use beta-blockers in cardiogenic shockAnna Vachulova (Bratislava, Slovakia)

9:30 - 9:45 - Removal of C-reactive protein as a new optionSteffen R. Mitzner (Rostock , Germany)

9:45 - 10:00 - Dipeptidyl peptidase (DPP3) as a promising targetAlexandre Mebazaa (Paris , France)

10:00 - 10:15 - Mechanical support of cardiogenic shockL Christian Napp (Hannover, Germany)

10:15 - 10:30 - Discussion

10:30 - 10:45 - Break

Fluid removal [Standard presentation] Moderator : Xavier Monnet (Le Kremlin-Bicêtre , France) Moderator : Alexander Zarbock (Münster, Germany) 10:45 - 11:00 - When to stop fluid resuscitationIvor Douglas (Denver, United States)

11:00 - 11:15 - We should avoid the term fluid overload Manu Malbrain (Brussels, Belgium)

11:15 - 11:30 - De-resuscitation: hope or hype?Jan De Waele (Ghent , Belgium)

11:30 - 11:45 - When to use diuretics safelyAlexandre Mebazaa (Paris , France)

11:45 - 12:00 - How I use ultrafiltration to de-escalate Patrick Honoré (Brussels, Belgium)

12:00 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : 400 Hall The ICU team [Standard presentation] Moderator : John J Marini (St Paul, United States) Moderator : Anthony McLean (Sydney , Australia) 13:45 - 14:00 - How to talk with a neurosurgeonPeter Le Roux (Wynnewood, United States)

14:00 - 14:15 - Have a surgeon in the teamJohn C Marshall (Toronto , Canada)

14:15 - 14:30 - Gender parityFlavia Machado (Sao Paulo , Brazil)

14:30 - 14:40 - Discussion

14:40 - 14:55 - How to ensure safety and team performanceErwan L'Her (Brest, France)

14:55 - 15:10 - Role of inter-professional shared decision-making in the ICUJ Randall Curtis (Seattle, United States)

15:10 - 15:25 - How to maintain the well-being of ICU doctorsMark Mikkelsen (Philadelphia, United States)

15:25 - 15:40 - How we incorporate nurse practitioners and physician assistants in the USCraig M Coopersmith (Atlanta, United States)

15:40 - 15:55 - Discussion

15:55 - 16:10 - We need advance practice providers in our ICUsStephen M Pastores (New York, United States)

16:10 - 16:25 - Is there one best staffing model for ICUs? Hannah Wunsch (Toronto, Canada)

16:25 - 16:40 - We need to apply behavioral scienceStephen Brett (London , United Kingdom)

16:40 - 16:55 - Discussion

How to improve ICU mobility [Tutorial] 16:55 - 17:25 - How to improve ICU mobilityCatherine L Hough (Seattle, United States)

Post-cardiac arrest care [Tutorial] 17:30 - 18:00 - Post-cardiac arrest careJerry Nolan (Bath, United Kingdom)

Wednesday 16 September 2020 - AM

ROOM : Panoramic Hall Who will develop sepsis? [Standard presentation] Moderator : Paul H Mayo (New Hyde Park, United States) Moderator : Frank van Haren (Canberra, Australia) 8:00 - 8:15 - Genetic predispositionJeremy Cohen (Brisbane, Australia)

8:15 - 8:30 - Paths into sepsisHallie Prescott (Ann Arbor, United States)

8:30 - 8:45 - Predicting sepsisGernot Marx (Aachen , Germany)

8:45 - 9:00 - The role of trained immunityEvangelos Giamarellos–Bourboulis (Athens, Greece)

9:00 - 9:15 - Is it so difficult to predict mortality?Benjamin Tang (Sydney, Australia)

9:15 - 9:30 - Discussion

New therapies for sepsis [Standard presentation] Moderator : Michael Mansour (Boston, United States) Moderator : Stephane Gaudry (Colombes, France) 9:30 - 9:45 - Statins… or cholesterol?Mervyn Singer (London, United Kingdom)

9:45 - 10:00 - Targeting septic coagulopathyChristian J Wiedermann (Innsbruck, Austria)

10:00 - 10:15 - Sepsis-induced immune suppression: epigenetics targetsJean-Daniel Chiche (Paris , France)

10:15 - 10:30 - Immunomarker-guided therapyEvangelos Giamarellos–Bourboulis (Athens, Greece)

10:30 - 10:45 - Immuno-restoration?Bruno François ( Limoges , France)

10:45 - 11:00 - Discussion

11:00 - 11:15 - Manipulating the circulating white cellsAnthony McLean (Sydney , Australia)

11:15 - 11:30 - Check point inhibitionCraig M Coopersmith (Atlanta, United States)

11:30 - 11:45 - Adrecizumab in patients with high adrenomedullin levelsPierre–François Laterre (Brussels , Belgium)

11:45 - 12:00 - Mitochondrial resuscitationAri Moskowitz (Boston, United States)

12:00 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : Panoramic Hall Assessing renal function [Standard presentation] Moderator : Ravindra Mehta (La Jolla, United States) Moderator : Detlef Kindgen–Milles (Düsseldorf , Germany) 13:45 - 14:00 - Contribution of ultrasoundJacques Duranteau (Le Kremlin-Bicêtre , France)

14:00 - 14:15 - How important is transient oliguria?John Kellum (Pittsburgh, United States)

14:15 - 14:30 - Furosemide stress test Jay Koyner (Chicago, United States)

14:30 - 14:45 - You should monitor continuous urine flowYaron Bar–Lavie (Haifa, Israel)

14:45 - 14:55 - Discussion

14:55 - 15:10 - Confounders of serum creatinine levelsHeleen Oudemans-Van Straaten (Amsterdam , Netherlands)

15:10 - 15:25 - Proenkephalin to assess renal functionGernot Marx (Aachen , Germany)

15:25 - 15:40 - Biomarkers: time for routine application?Claudio Ronco (Vicenza, Italy)

15:40 - 15:55 - Predicting recoveryLui Forni (Guildford, United Kingdom)

15:55 - 16:05 - Discussion

Acute respiratory failure [Standard presentation] Moderator : B Taylor Thompson (Boston , United States) Moderator : Marcelo Amato (Sao Paulo , Brazil) 16:05 - 16:20 - Submersion-induced pulmonary edemaPeter Radermacher (Ulm , Germany)

16:20 - 16:35 - Are lung and chest wall compliances important?Alain Mercat (Angers , France)

16:35 - 16:50 - Relationship between mechanical indices and clinical outcomesGiacomo Bellani (Monza, Italy)

16:50 - 17:00 - Discussion

17:00 - 17:15 - Driving pressure as a risk factor for ARDS in non-injured lungOriol Roca (Barcelona , Spain)

17:15 - 17:30 - So, should we ventilate non-ARDS patients differently?Paolo Pelosi (Genoa , Italy)

17:30 - 17:45 - How artificial intelligence may helpAnthony Gordon (London , United Kingdom)

17:45 - 18:00 - Discussion

Wednesday 16 September 2020 - AM

ROOM : Studio Room Blood purification [Standard presentation] Moderator : John Kellum (Pittsburgh, United States) Moderator : Lui Forni (Guildford, United Kingdom) 8:00 - 8:15 - A critical appraisal of current evidencePeter Pickkers (Nijmegen, Netherlands)

8:15 - 8:30 - What are the hurdles?Axel Nierhaus (Hamburg , Germany)

8:30 - 8:45 - Effects on antibiotic removalDetlef Kindgen–Milles (Düsseldorf , Germany)

8:45 - 9:00 - Discussion

9:00 - 9:15 - Hemodynamic impact of cytokine adsorbersCan Ince (Amsterdam , Netherlands)

9:15 - 9:30 - How we could improve flow dynamic characteristics of current devicesClaudio Ronco (Vicenza, Italy)

9:30 - 9:45 - Can we also eliminate circulating bacteria?Herwig Gerlach (Berlin , Germany)

9:45 - 10:00 - Discussion

10:00 - 10:15 - Break

Extracorporeal organ support (ECOS) [Standard presentation] Moderator : Daniel Brodie (New York, United States) Moderator : Dietmar Fries (Innsbruck, Austria) 10:15 - 10:30 - Key principles of VV-ECMOAntonio Pesenti (Milan , Italy)

10:30 - 10:45 - Key principles of VA-ECMOL Christian Napp (Hannover, Germany)

10:45 - 11:00 - Heart support systemsRoberto Lorusso (Maastricht, Netherlands)

11:00 - 11:15 - Discussion

11:15 - 11:30 - Liver support systemsJavier Fernandez (Barcelona , Spain)

11:30 - 11:45 - Kidney support systemsClaudio Ronco (Vicenza, Italy)

11:45 - 12:00 - Immunomodulating systemsSteffen R. Mitzner (Rostock , Germany)

12:00 - 12:15 - Discussion

Wednesday 16 September 2020 - PM

ROOM : Studio Room Bundles [Standard presentation] Moderator : Michael W Donnino (Boston, United States) Moderator : Marlies Ostermann (London , United Kingdom) 13:45 - 14:00 - The 1-hour sepsis bundle: pro and conFlavia Machado (Sao Paulo , Brazil)

14:00 - 14:15 - The Golden Hour concept in severe trauma does not workPierre Bouzat (Grenoble, France)

14:15 - 14:30 - Bundled care: sometimes it really is a prize packageHeatherlee Bailey (Durham, United States)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Bundles in renal failureEric Hoste (Ghent , Belgium)

15:00 - 15:15 - Bundles workChristopher Seymour (Pittsburgh, United States)

15:15 - 15:30 - Bundles do not workJean-Louis Vincent (Brussels , Belgium)

15:30 - 15:45 - Discussion

When I give albumin [Standard presentation] Moderator : James Krinsley (Stamford , United States) Moderator : Sebastian Wicha (Hamburg, Germany) 15:45 - 16:00 - What about gelatins?Dietmar Fries (Innsbruck, Austria)

16:00 - 16:15 - Hypoalbuminemia increases the risk of sepsisChristian J Wiedermann (Innsbruck, Austria)

16:15 - 16:30 - Effective albumin concentration: a surrogate marker of albumin function?Paolo Caraceni (Bologna, Italy)

16:30 - 16:45 - The advantages of hyperoncotic albuminJonathan Bannard–Smith (Manchester, United Kingdom)

16:45 - 17:00 - Discussion

17:00 - 17:15 - Does albumin not leak out rapidly?Robert G Hahn (Södertälje, Sweden)

17:15 - 17:30 - Albumin as part of large-volume resuscitation can improve survivalJohn Kellum (Pittsburgh, United States)

17:30 - 17:45 - Albumin vs. starch?Greg Martin (Atlanta, United States)

17:45 - 18:00 - Discussion

Wednesday 16 September 2020 - AM

ROOM : 300 Hall Initial management of severe trauma 1 [Simulation Session] Moderator : Peter Radermacher (Ulm , Germany) 8:45 - 9:30 - Initial Management of severe trauma

9:30 - 10:00 - Break

Initial management of severe trauma 2 [Simulation Session] Moderator : Peter Radermacher (Ulm , Germany) 10:00 - 10:45 - Initial Management of severe trauma

10:45 - 11:15 - Break

Thrombotic microangiopathy: gasping for PEX [Simulation Session] Moderator : Elie Azoulay (Paris , France) 11:15 - 12:00 - Thrombotic microangiopathy: gasping for PEX Beverley Hunt (London , United Kingdom), Peter Pickkers (Nijmegen, Netherlands)

Wednesday 16 September 2020 - PM

ROOM : 300 Hall Assessment of thrombocytopenia 1 [Meet the experts] 13:45 - 14:15 - Assessment of thrombocytopeniaBeverley Hunt (London , United Kingdom), Pieter Van Paassen (Maastricht, Netherlands)

14:15 - 15:15 - Break

Blood purification in septic shock [Simulation Session] Moderator : Peter Pickkers (Nijmegen, Netherlands) 15:15 - 16:00 - Blood purification in septic shockManish Kaushik (Singapore, Singapore)

16:00 - 16:45 - Break

TTM in cardiac arrest from non-shockable rhythms [Simulation Session] Moderator : Mark Dunn (Edinburgh, United Kingdom) 16:45 - 17:30 - TTM in cardiac arrest from non-shockable rhythmsMarkus Skrifvars (Helsinki, Finland)

Wednesday 16 September 2020 - AM

ROOM : Arc Room

Wednesday 16 September 2020 - AM

ROOM : Corner B (Exhibition Area)

Wednesday 16 September 2020 - PM

ROOM : Corner B (Exhibition Area) Managing conflicts [Meet the experts] 14:00 - 14:30 - Managing conflictsStephen M Pastores (New York, United States), Victoria Metaxa (London, United Kingdom)

Complicated chest trauma [Meet the experts] 14:35 - 15:05 - Complicated chest traumaMichael Reade (Brisbane, Australia), Niels Martin (Philadelphia, United States)

How I manage intracranial hypertension [Meet the experts] 15:10 - 15:40 - How I manage intracranial hypertensionPeter Le Roux (Wynnewood, United States), Geert Meyfroidt (Leuven , Belgium)

Targeted temperature management for brain protection [Meet the experts] 15:45 - 16:15 - Targeted temperature management for brain protectionNiklas Nielsen (Helsingborg, Sweden), Markus Skrifvars (Helsinki, Finland)

Wednesday 16 September 2020 - AM

ROOM : Lung House (Exhibition Area)

Wednesday 16 September 2020 - PM

ROOM : Lung House (Exhibition Area) Driving pressure and spontaneous breathing during assisted ventilation [Meet the experts] 17:00 - 18:00 - Driving pressure and spontaneous breathing during assisted ventilationGiacomo Bellani (Monza, Italy)

Wednesday 16 September 2020 - AM

ROOM : Neuro-Lab (Exhibition Area)

Wednesday 16 September 2020 - PM

ROOM : Neuro-Lab (Exhibition Area) Targeted temperature management in 2020 [Meet the experts] 17:00 - 18:00 - Targeted temperature management in 2020: state of the artFabio S. Taccone (Brussels , Belgium)

Thursday 17 September 2020 - AM

ROOM : HLB Room

Thursday 17 September 2020 - AM

ROOM : Gold Hall More fluids... or more pressors? [Standard presentation] Moderator : Djillali Annane (Garches , France) Moderator : Wesley Self (Nashville, United States) 8:00 - 8:15 - How important is the question?Jean-Louis Vincent (Brussels , Belgium)

8:15 - 8:30 - Combining fluids and vasopressors makes a lot of senseJean-Louis Teboul (Le Kremlin-Bicêtre, France)

8:30 - 8:45 - Discussion

8:45 - 9:00 - in sepsisMaurizio Cecconi (Rozzano, MI, Italy)

9:00 - 9:15 - In respiratory failureGreg Martin (Atlanta, United States)

9:15 - 9:30 - In cardiac failureAlexandre Mebazaa (Paris , France)

9:30 - 9:45 - In renal failureMarlies Ostermann (London , United Kingdom)

9:45 - 10:00 - In acute brain injury Mauro Oddo (Lausanne , Switzerland)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Can natriuretic peptides help?Alexandre Mebazaa (Paris , France)

10:30 - 10:45 - Trust the computer, not the physicianAnthony Gordon (London , United Kingdom)

10:45 - 11:00 - Discussion

POSTER AWARDS [Standard presentation] 11:00 - 11:15 - POSTER AWARDSXavier Monnet (Le Kremlin-Bicêtre , France)

In the ambulance [Standard presentation] Moderator : Keyvan Karkouti (Toronto, Canada) Moderator : Lionel Lamhaut (Paris, France) 11:15 - 11:30 - Severe brain injury: stabilization or immediate transfer to a neurotrauma center? Nino Stocchetti (Milan , Italy)

11:30 - 11:45 - What is the optimal trauma organization?-Pierre Bouzat (Grenoble, France)

11:45 - 12:00 - Do we need cardiac arrest centers?Jerry Nolan (Bath, United Kingdom)

12:00 - 12:15 - Discussion

Thursday 17 September 2020 - PM

ROOM : Gold Hall Polytrauma [Standard presentation] Moderator : Paul E Pepe (Dallas , United States) Moderator : Mauro Oddo (Lausanne , Switzerland) 13:45 - 14:00 - When to intubate the conscious patient Markus Skrifvars (Helsinki, Finland)

14:00 - 14:15 - Initial bleeding managementDietmar Fries (Innsbruck, Austria)

14:15 - 14:30 - REBOA in major traumaLionel Lamhaut (Paris, France)

14:30 - 14:45 - Damage control surgeryMarc Maegele (Cologne , Germany)

14:45 - 15:00 - Pelvic fractureJacques Duranteau (Le Kremlin-Bicêtre , France)

15:00 - 15:15 - Trauma trials on the horizonMichael Reade (Brisbane, Australia)

15:15 - 15:25 - Discussion

Fluid challenge [Standard presentation] Moderator : Craig M Coopersmith (Atlanta, United States) Moderator : Dwight Bailey (Charlotte, United States) 15:25 - 15:40 - Too much fluid can reduce DO2 by hemodilutionAzriel Perel (Tel Aviv , Israel)

15:40 - 15:55 - What people do in practiceJan Bakker (New York, United States)

15:55 - 16:10 - Fluid challenge: how to get this right?Maurizio Cecconi (Rozzano, MI, Italy)

16:10 - 16:25 - I’ll tell you how I do itJean-Louis Vincent (Brussels , Belgium)

16:25 - 16:35 - Discussion

16:35 - 16:50 - We can guide fluid resuscitation with non-invasive monitoringWesley Self (Nashville, United States)

16:50 - 17:05 - A FRESH look at passive leg raising-guided fluid resuscitationIvor Douglas (Denver, United States)

17:05 - 17:20 - End-expiratory occlusion test and tidal volume challengeJean-Louis Teboul (Le Kremlin-Bicêtre, France)

17:20 - 17:35 - Limits of fluid-responsivenessMichel Slama (Amiens , France)

17:35 - 17:50 - Predicting fluid responsiveness: time for automationFrédéric Michard (Lausanne, Switzerland)

17:50 - 18:00 - Discussion

Thursday 17 September 2020 - AM

ROOM : Copper Hall Improving antibiotic strategies [Standard presentation] Moderator : Manu Shankar–Hari (London, United Kingdom) Moderator : Michael Bauer (Jena , Germany) 8:00 - 8:15 - A hospital-wide antibiotic stewardship program can improve outcomesAndrea Kwa (Singapore, Singapore)

8:15 - 8:30 - Are carbapenems still the best treatment option for Gram-negative sepsis?Matteo Bassetti (Genova, Italy)

8:30 - 8:45 - Macrolides: life-saving agents? Evangelos Giamarellos–Bourboulis (Athens, Greece)

8:45 - 9:00 - Is there a future for inhaled antibiotics in the ICU?Michael S Niederman (New York, United States)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Antibiotic de-escalation: how to do it?Jan De Waele (Ghent , Belgium)

9:30 - 9:45 - The less known harmful effects of antibioticsMervyn Singer (London, United Kingdom)

9:45 - 10:00 - Discussion

10:00 - 10:15 - Break

Which fluid? [Standard presentation] Moderator : Ivor Douglas (Denver, United States) Moderator : Sigismond Lasocki (Angers, France) 10:15 - 10:30 - We give too much saltNiels Van Regenmortel (Antwerp, Belgium)

10:30 - 10:45 - We give too much chlorideJohn Kellum (Pittsburgh, United States)

10:45 - 11:00 - How fluids can affect the endothelial glycocalyxVladimir Cerny (Usti nad Labem, Czech Republic)

11:00 - 11:15 - Discussion

11:15 - 11:30 - Traumatic hemorrhagic shock: which fluid?Jacques Duranteau (Le Kremlin-Bicêtre , France)

11:30 - 11:45 - Colloid in high-risk surgical patients: new answers to an old storyAlexandre Joosten (Le Kremlin-Bicêtre, France)

11:45 - 12:00 - Still a place for crystalloids?Lui Forni (Guildford, United Kingdom)

12:00 - 12:15 - Discussion

Thursday 17 September 2020 - PM

ROOM : Copper Hall ECMO for ARDS [Standard presentation] Moderator : Luciano Gattinoni (Göttingen, Germany) Moderator : Daniel Brodie (New York, United States) 13:45 - 14:00 - High-flow ECMO and oxygenation: myths and truthsMichael Quintel (Göttingen , Germany)

14:00 - 14:15 - AnticoagulationMaximilian Malfertheiner (Regensburg, Germany)

14:15 - 14:30 - Bleeding complicationsJerrold H Levy (Durham, United States)

14:30 - 14:45 - Discussion

14:45 - 15:00 - How to manage renal failureMarlies Ostermann (London , United Kingdom)

15:00 - 15:15 - Neurologic complicationsRomain Sonneville (Paris, France)

15:15 - 15:30 - Discussion

15:30 - 15:45 - Break

Oxygen: just enough but not too much [Standard presentation] Moderator : Philip Hopkins (London, United Kingdom) Moderator : Benjamin Tang (Sydney, Australia) 15:45 - 16:00 - Pathophysiologic effects of hyperoxiaErwan L'Her (Brest, France)

16:00 - 16:15 - Can one tolerate moderate hypoxemia?Massimo Girardis (Modena , Italy)

16:15 - 16:30 - Perioperative hyperoxiaCarlos Ferrando (Barcelona, Spain)

16:30 - 16:45 - Is it different after cardiac arrest?Fabio S. Taccone (Brussels , Belgium)

16:45 - 17:00 - Discussion

17:00 - 17:15 - Is there an ´´ideal´´ PaO2 in TBI?Peter Radermacher (Ulm , Germany)

17:15 - 17:30 - How to avoid hyperoxia in practiceSigismond Lasocki (Angers, France)

17:30 - 17:45 - How can we optimize oxygen administration?Azriel Perel (Tel Aviv , Israel)

17:45 - 18:00 - Discussion

Thursday 17 September 2020 - AM

ROOM : Salle M (Bozar)

Thursday 17 September 2020 - AM

ROOM : Tent What you should know about genomics [Tutorial] 8:00 - 8:40 - What you should know about genomicsAnthony McLean (Sydney , Australia)

Respiratory monitoring [Standard presentation] Moderator : Michael R. Pinsky (Pittsburgh, United States) Moderator : Michael Quintel (Göttingen , Germany) 8:45 - 9:00 - Radiographic assessment of lung edema: the RALE scoreLorraine B Ware (Nashville , United States)

9:00 - 9:15 - Targeting transpulmonary pressure: does it make a difference?Daniel Talmor (Boston , United States)

9:15 - 9:30 - When and how I measure esophageal pressure in adults and childrenTom Schepens (Edegem, Belgium)

9:30 - 9:45 - Discussion

9:45 - 10:00 - Pleural-esophageal pressure differenceLuciano Gattinoni (Göttingen, Germany)

10:00 - 10:15 - Assessing recruitment at the bedsideDiederik Gommers (Rotterdam, Netherlands)

10:15 - 10:30 - New developments in electrical impedance tomographyMarcelo Amato (Sao Paulo , Brazil)

10:30 - 10:45 - Continuous monitoring of end-expiratory lung volumeFernando Suarez Sipmann (Uppsala, Sweden)

10:45 - 11:00 - Discussion

11:00 - 11:15 - Matching respiratory physiology and lung imagingAntonio Pesenti (Milan , Italy)

11:15 - 11:30 - Sampling exhaled breath using the heat and moisture exchange filterLorraine B Ware (Nashville , United States)

11:30 - 11:45 - Respiratory mechanics in obese patients with ARDSRémi Coudroy (Poitiers, France)

11:45 - 12:00 - An integrated approachLeo Heunks (Amsterdam, Netherlands)

12:00 - 12:15 - Discussion

Thursday 17 September 2020 - PM

ROOM : Tent Every hemodynamic variable is important in sepsis [Standard presentation] Moderator : Ivor Douglas (Denver, United States) Moderator : Bruno François ( Limoges , France) 13:45 - 14:00 - Arterial pressureMichael R. Pinsky (Pittsburgh, United States)

14:00 - 14:15 - Capillary refill timeJan Bakker (New York, United States)

14:15 - 14:30 - Central venous pressureMaurizio Cecconi (Rozzano, MI, Italy)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Cardiac outputXavier Monnet (Le Kremlin-Bicêtre , France)

15:00 - 15:15 - Hemoglobin O2 venous saturationJean-Louis Vincent (Brussels , Belgium)

15:15 - 15:30 - Tissue CO2Guillermo Gutierrez (Washington, United States)

15:30 - 15:45 - Discussion

15:45 - 16:00 - PvaCO2 gradients Daniel De Backer (Brussels, Belgium)

16:00 - 16:15 - Blood lactateNiels Martin (Philadelphia, United States)

16:15 - 16:30 - None is very goodJacques Duranteau (Le Kremlin-Bicêtre , France)

16:30 - 16:45 - Discussion

Still a place for endotoxin removal? [Plenary lecture] 16:50 - 17:15 - Still a place for endotoxin removal?Claudio Ronco (Vicenza, Italy)

How I assess tissue hypoxia at the bedside [Tutorial] 17:20 - 18:00 - How I assess tissue hypoxia at the bedsideXavier Monnet (Le Kremlin-Bicêtre , France)

Thursday 17 September 2020 - AM

ROOM : Silver Hall A new look at CPR [Standard presentation] Moderator : L Christian Napp (Hannover, Germany) Moderator : Clifton Callaway (Pittsburgh, United States) 8:00 - 8:15 - In-hospital cardiac arrests: epidemiology and outcomesDaryl Jones (Heidelberg, Australia)

8:15 - 8:30 - Can we treat in-hospital cardiac arrest based on out-of-hospital data?Katherine Berg (Boston, United States)

8:30 - 8:45 - Do guidelines make a difference for cardiac arrest?Lars Wiuff Andersen (Aarhus, Denmark)

8:45 - 9:00 - Discussion

9:00 - 9:15 - Should we even start CPR when the cause is neurological?Markus Skrifvars (Helsinki, Finland)

9:15 - 9:30 - Is pediatric cardiac arrest different?Paul E Pepe (Dallas , United States)

9:30 - 9:45 - Cardiac arrest in the ICU: an opportunity for prevention?Ari Moskowitz (Boston, United States)

9:45 - 10:00 - CO2 during CPR: a novel physiological interpretationJean-Christophe Richard (Angers, France)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Break

What I learned about the recent COVID-19 epidemic? [Standard presentation] 10:30 - 12:15 - TBA

Thursday 17 September 2020 - PM

ROOM : Silver Hall Rapid bacteriological testing [Standard presentation] Moderator : Evangelos Giamarellos–Bourboulis (Athens, Greece) Moderator : Axel Nierhaus (Hamburg , Germany) 13:45 - 14:00 - When can molecular testing replace blood culture?Michael Bauer (Jena , Germany)

14:00 - 14:15 - The pros and cons of the new toolsTobias Welte (Hannover , Germany)

14:15 - 14:30 - New molecular methods for pneumoniaJean–François Timsit (Paris, France)

14:30 - 14:45 - Can we use local antibiograms to optimize therapy?Michael S Niederman (New York, United States)

14:45 - 15:00 - Discussion

15:00 - 15:15 - Break

Preventing renal failure [Standard presentation] Moderator : Detlef Kindgen–Milles (Düsseldorf , Germany) Moderator : Pieter Van Paassen (Maastricht, Netherlands) 15:15 - 15:30 - Who will develop it?Ravindra Mehta (La Jolla, United States)

15:30 - 15:45 - Acute renal stress before failureJohn Kellum (Pittsburgh, United States)

15:45 - 16:00 - Discussion

16:00 - 16:15 - How mechanical ventilation can impair renal functionAntoine Vieillard–Baron (Boulogne-Billancourt, France)

16:15 - 16:30 - What are the therapeutic options?Alexander Zarbock (Münster, Germany)

16:30 - 16:45 - In surgical patientsCarole Ichai (Nice, France)

16:45 - 17:00 - Discussion

17:00 - 17:15 - The importance of blood pressureLaurence Busse (Atlanta, United States)

17:15 - 17:30 - Other hemodynamic strategiesMatthias Heringlake (Lübeck , Germany)

17:30 - 17:45 - Non-hemodynamic strategiesJay Koyner (Chicago, United States)

17:45 - 18:00 - Discussion

Thursday 17 September 2020 - AM

ROOM : 100 Hall Stroke [Standard presentation] Moderator : Peter Radermacher (Ulm , Germany) Moderator : Niels Martin (Philadelphia, United States) 8:00 - 8:15 - The interventional treatment window has expanded Paul Vespa (Los Angeles , United States)

8:15 - 8:30 - Outcomes have improvedRomain Sonneville (Paris, France)

8:30 - 8:45 - Initial management of subarachnoid hemorrhageAndrea Lavinio (Cambridge , United Kingdom)

8:45 - 9:00 - Hemodynamic management of subarachnoid hemorrhageChiara Robba (Genova, Italy)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Delayed cerebral ischemia after subarachnoid hemorrhage Fabio S. Taccone (Brussels , Belgium)

9:30 - 9:45 - Minimally invasive surgery for brain hemorrhagePaul Vespa (Los Angeles , United States)

9:45 - 10:00 - Intracranial hemorrhage: when to give up?Markus Skrifvars (Helsinki, Finland)

10:00 - 10:10 - Discussion

Practical aspects for the neurologic patient [Standard presentation] Moderator : Peter Le Roux (Wynnewood, United States) Moderator : Carole Ichai (Nice, France) 10:10 - 10:25 - Emergency diagnosis and treatment of seizuresPaul Vespa (Los Angeles , United States)

10:25 - 10:40 - Optimizing mechanical ventilationChiara Robba (Genova, Italy)

10:40 - 10:55 - Optimizing brain metabolismPierre Bouzat (Grenoble, France)

10:55 - 11:10 - Optimizing brain perfusion Mauro Oddo (Lausanne , Switzerland)

11:10 - 11:25 - Providing RRTManish Kaushik (Singapore, Singapore)

11:25 - 11:40 - Discussion

Severe CAP [Tutorial] 11:45 - 12:15 - Severe CAPMichael S Niederman (New York, United States)

Thursday 17 September 2020 - PM

ROOM : 100 Hall Cardiac surgery: perioperative care [Standard presentation] Moderator : André Denault (Montreal, Canada) Moderator : Keyvan Karkouti (Toronto, Canada) 13:45 - 14:00 - Hemodynamic optimizationThomas Scheeren (Groningen, Netherlands)

14:00 - 14:15 - Levosimendan in the high-risk patientMatthias Heringlake (Lübeck , Germany)

14:15 - 14:30 - Rescue strategies for vasoplegiaLaurence Busse (Atlanta, United States)

14:30 - 14:45 - Discussion

14:45 - 15:00 - VasopressinLudhmila Hajjar (Sao Paulo, Brazil)

15:00 - 15:15 - Associated renal failureAlexander Zarbock (Münster, Germany)

15:15 - 15:30 - The place of extracorporeal life supportRoberto Lorusso (Maastricht, Netherlands)

15:30 - 15:45 - Discussion

Difficult extubation and beyond [Standard presentation] Moderator : Andrew Klein (Cambridge, United Kingdom) Moderator : Ewan Goligher (Toronto, Canada) 15:45 - 16:00 - How weaning is actually doneGiacomo Bellani (Monza, Italy)

16:00 - 16:15 - Weaning failure of cardiac originXavier Monnet (Le Kremlin-Bicêtre , France)

16:15 - 16:30 - Managing failed extubationJames Krinsley (Stamford , United States)

16:30 - 16:45 - Oxygenation strategies after extubation to avoid reintubationRémi Coudroy (Poitiers, France)

16:45 - 17:00 - Discussion

17:00 - 17:15 - Tracheostomy now: what happens later?Alexandre Mebazaa (Paris , France)

17:15 - 17:30 - Tracheostomy: less is more?Paolo Pelosi (Genoa , Italy)

17:30 - 17:45 - Respiratory muscle rehabilitationFrank van Haren (Canberra, Australia)

17:45 - 18:00 - Discussion

Thursday 17 September 2020 - AM

ROOM : Terarken (BOZAR) Optimizing perioperative ventilation [Standard presentation] Moderator : Thomas Scheeren (Groningen, Netherlands) Moderator : V Marco Ranieri (Bologna, Italy) 8:00 - 8:15 - Perioperative protective ventilationCarlos Ferrando (Barcelona, Spain)

8:15 - 8:30 - Lower PEEP is betterPaolo Pelosi (Genoa , Italy)

8:30 - 8:45 - Discussion

8:45 - 9:00 - High-flow nasal therapy after major surgeryAndrew Klein (Cambridge, United Kingdom)

9:00 - 9:15 - High-flow nasal therapy in thoracic surgery: Really a plus? Massimo Antonelli (Rome, Italy)

9:15 - 9:30 - Postoperative non-invasive ventilation: what to choose?Samir Jaber (Montpellier, France)

9:30 - 9:45 - Discussion

9:45 - 10:00 - Break

Early management of sepsis [Standard presentation] Moderator : Michel Slama (Amiens , France) Moderator : Craig M Coopersmith (Atlanta, United States) 10:00 - 10:15 - Ongoing controversiesFlavia Machado (Sao Paulo , Brazil)

10:15 - 10:30 - Do not forget source controlJan De Waele (Ghent , Belgium)

10:30 - 10:45 - Should we remove dialysis and central venous catheters?Jean–François Timsit (Paris, France)

10:45 - 11:00 - Is early use of antibiotics so important?Thierry Calandra (Lausanne , Switzerland)

11:00 - 11:15 - Discussion

11:15 - 11:30 - Still fluids first.... and then the rest?Fabio Guarracino (Pisa, Italy)

11:30 - 11:45 - Early use of vasopressors is preferableJan Bakker (New York, United States)

11:45 - 12:00 - My multimodal therapeutic approachDwight Bailey (Charlotte, United States)

12:00 - 12:15 - Discussion

Thursday 17 September 2020 - PM

ROOM : Terarken (BOZAR) ARDS: keep the lung open [Pro-con debate] Moderator : Alain Combes (Paris , France) 13:45 - 14:20 - ARDS: keep the lung open PRO Marcelo Amato (Sao Paulo , Brazil) CON Paolo Pelosi (Genoa , Italy)

Less is more [Pro-con debate] Moderator : Jonathan Bannard–Smith (Manchester, United Kingdom) 14:25 - 15:00 - Less is more CON Daniel De Backer (Brussels, Belgium) PRO Greg Martin (Atlanta, United States)

ECMO should be available in every ICU [Pro-con debate] Moderator : Jeremy Beitler (New York, United States) 15:05 - 15:40 - ECMO should be available in every ICU CON Alain Combes (Paris , France) PRO L Christian Napp (Hannover, Germany)

High PEEP is protective in severe ARDS [Pro-con debate] Moderator : Diederik Gommers (Rotterdam, Netherlands) 15:45 - 16:20 - High PEEP is protective in severe ARDS PRO Marcelo Amato (Sao Paulo , Brazil) CON Luciano Gattinoni (Göttingen, Germany)

Individualized nutritional support [Standard presentation] Moderator : Stephane Gaudry (Colombes, France) Moderator : Jean-Charles Preiser (Brussels , Belgium) 16:25 - 16:40 - Early protein intakeHeleen Oudemans-Van Straaten (Amsterdam , Netherlands)

16:40 - 16:55 - Indirect calorimetry is a mustPierre Singer (Petah Tikva , Israel)

16:55 - 17:10 - Nutrition in renal failureEric Hoste (Ghent , Belgium)

17:10 - 17:25 - Nutrition in brain injuryMauro Oddo (Lausanne , Switzerland)

17:25 - 17:40 - Nutrition in the obese patientPaul Wischmeyer (Durham, United States)

17:40 - 18:00 - Discussion

Thursday 17 September 2020 - AM

ROOM : 400 Hall Severe viral diseases [Standard presentation] Moderator : Elias N Baedorf Kassis (Boston, United States) Moderator : Bruno François ( Limoges , France) 8:00 - 8:15 - Influenza infections: what is establishedIgnacio Martin-Loeches (Dublin , Ireland)

8:15 - 8:30 - COVID-19 outbreak… urgent challenge in diagnosis and risk managementBenjamin Tang (Sydney, Australia)

8:30 - 8:45 - RSV infectionDavid Grimaldi (Brussels, Belgium)

8:45 - 9:00 - Detecting CMV reactivationNicole Juffermans (Amsterdam , Netherlands)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Should HSV and CMV reactivation be treated?Laurent Papazian (Marseille , France)

9:30 - 9:45 - The new antiviral agentsTobias Welte (Hannover , Germany)

9:45 - 10:00 - Bleeding in the viral hemorrhagic feversBeverley Hunt (London , United Kingdom)

10:00 - 10:15 - Discussion

10:15 - 10:25 - Break

Pharmacology of antibiotics (in collaboration with ISAP - International Society of Anti-InfectivePharmacology) [Standard presentation] Moderator : Iris Minichmayr (Uppsala, Sweden) Moderator : Sebastian Wicha (Hamburg, Germany) 10:25 - 10:40 - What I have learnt from antibiotic PK in critically ill patientsFabio S. Taccone (Brussels , Belgium)

10:40 - 10:55 - Pharmacokinetic-pharmacodynamic relationships of antimicrobialsIris Minichmayr (Uppsala, Sweden)

10:55 - 11:10 - Therapeutic drug monitoring of beta-lactam antibiotics: yes or no?Jan De Waele (Ghent , Belgium)

11:10 - 11:25 - Interactive case studies to individualize dosing (bring your tablet or laptop)Sebastian Wicha (Hamburg, Germany)

11:25 - 11:40 - Discussion

My approach to severe hypoxemia [Tutorial] 11:45 - 12:15 - My approach to severe hypoxemiaJean-Daniel Chiche (Paris , France)

Thursday 17 September 2020 - PM

ROOM : 400 Hall How to manage severe hypoxemia? [Round table] Moderator : Jean-Daniel Chiche (Paris , France) 13:45 - 14:35 - How to manage severe hypoxemia?Niall Ferguson (Toronto , Canada), Massimo Girardis (Modena , Italy), Wesley Self (Nashville, UnitedStates), Fernando Suarez Sipmann (Uppsala, Sweden)

How to personalize mechanical ventilation [Round table] Moderator : John J Marini (St Paul, United States) 14:40 - 15:30 - How to personalize mechanical ventilationAlain Mercat (Angers , France), Laurent Papazian (Marseille , France), V Marco Ranieri (Bologna, Italy), BTaylor Thompson (Boston , United States)

Respiratory failure in hematologic patients [Tutorial] 15:35 - 16:10 - Respiratory failure in hematologic patientsVictoria Metaxa (London, United Kingdom)

How to use mechanical ventilation under ECMO [Round table] Moderator : Daniel Brodie (New York, United States) 16:15 - 17:05 - How to use mechanical ventilation under ECMOEddy Fan (Toronto, Canada), Antonio Pesenti (Milan , Italy), Michael Quintel (Göttingen , Germany)

The future of hemodynamic monitoring (with participation of the industry) [Round table] Moderator : Michael Sander (Giessen, Germany) 17:10 - 18:00 - The future of hemodynamic monitoring (with participation of the industry)Thomas Scheeren (Groningen, Netherlands), Jan Bakker (New York, United States), Olivier Huet (Brest,France), Maxime Cannesson (Los Angeles, United States)

Thursday 17 September 2020 - AM

ROOM : Panoramic Hall ICP monitoring [Standard presentation] Moderator : Mark Dunn (Edinburgh, United Kingdom) Moderator : Nino Stocchetti (Milan , Italy) 8:00 - 8:15 - Optic nerve sheath diameter for non-invasive estimation of ICPChiara Robba (Genova, Italy)

8:15 - 8:30 - Can automated pupillometry help? Lionel Velly (Marseille , France)

8:30 - 8:45 - Discussion

8:45 - 9:00 - Invasive ICP monitoring can be inserted by ICU doctorsFrank Rasulo (Brescia, Italy)

9:00 - 9:15 - ICP guided-therapyGiuseppe Citerio (Monza, Italy)

9:15 - 9:30 - It should be combined with PbtO2 monitoringMauro Oddo (Lausanne , Switzerland)

9:30 - 9:45 - Discussion

9:45 - 10:00 - Break

TTM revisited [Standard presentation] Moderator : Giuseppe Citerio (Monza, Italy) Moderator : Geert Meyfroidt (Leuven , Belgium) 10:00 - 10:15 - Targeted temperature should be 36°CNiklas Nielsen (Helsingborg, Sweden)

10:15 - 10:30 - Targeted temperature should be 33-34°CMauro Oddo (Lausanne , Switzerland)

10:30 - 10:45 - So, how cool is cool ?Mark Dunn (Edinburgh, United Kingdom)

10:45 - 11:00 - Discussion

11:00 - 11:15 - TTM should be prolongedMarkus Skrifvars (Helsinki, Finland)

11:15 - 11:30 - High quality TTMFabio S. Taccone (Brussels , Belgium)

11:30 - 11:45 - Selective TTM in stroke?Andrea Lavinio (Cambridge , United Kingdom)

11:45 - 12:00 - What will be the treatment in a year from now? Niklas Nielsen (Helsingborg, Sweden)

12:00 - 12:15 - Discussion

Thursday 17 September 2020 - PM

ROOM : Panoramic Hall When the cause of renal failure is not evident [Tutorial] 13:45 - 14:15 - When the cause of renal failure is not evidentManuel Praga (Madrid, Spain)

Burns management [Tutorial] 14:20 - 14:50 - Burns managementJeremy Cohen (Brisbane, Australia)

How to start studying the microcirculation [Tutorial] 14:55 - 15:25 - How to start studying the microcirculationCan Ince (Amsterdam , Netherlands)

Glucose control in the ICU [Tutorial] 15:30 - 16:05 - Glucose control in the ICUGrant Bochicchio (St Louis, United States)

Initial management of decompensated cirrhosis [Tutorial] 16:10 - 16:40 - Initial management of decompensated cirrhosisJavier Fernandez (Barcelona , Spain)

CRRT: practical issues [Tutorial] 16:45 - 17:20 - CRRT: practical issuesManish Kaushik (Singapore, Singapore)

Respiratory mechanics [Tutorial] 17:25 - 18:00 - Respiratory mechanicsLeo Heunks (Amsterdam, Netherlands)

Thursday 17 September 2020 - AM

ROOM : Studio Room Analgo-sedation [Standard presentation] Moderator : E Wesley Ely (Nashville, United States) Moderator : Gernot Marx (Aachen , Germany) 8:00 - 8:15 - Should we be concerned about opioid prescribing in the ICU?Hannah Wunsch (Toronto, Canada)

8:15 - 8:30 - Rethinking sedation targets in mechanical ventilationJeremy Beitler (New York, United States)

8:30 - 8:45 - In the neurological patientVictoria McCredie (Toronto, Canada)

8:45 - 9:00 - During non-invasive ventilation Massimo Girardis (Modena , Italy)

9:00 - 9:15 - Discussion

9:15 - 9:30 - A place for inhaled agents?Philipp Lepper (Homburg, Germany)

9:30 - 9:45 - Anti-inflammatory effects of volatile anestheticsMartin Schläpfer (Zürich, Switzerland)

9:45 - 10:00 - Is propofol safe after all?Arthur van Zanten (Ede, Netherlands)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Propofol can contribute to ICU-acquired weaknessPaul Wischmeyer (Durham, United States)

10:30 - 10:45 - Time for a consensus regarding EEG-guided sedation in the ICU Frank Rasulo (Brescia, Italy)

10:45 - 11:00 - Improving sedation quality through education programsTimothy Walsh (Edinburgh , United Kingdom)

11:00 - 11:15 - Discussion

The ICU family conference [Tutorial] 11:20 - 11:50 - The ICU family conferenceJ Randall Curtis (Seattle, United States)

How to assess work of breathing [Tutorial] 11:55 - 12:25 - How to assess work of breathingGiacomo Bellani (Monza, Italy)

Thursday 17 September 2020 - PM

ROOM : Studio Room After cardiac arrest [Standard presentation] Moderator : Chiara Robba (Genova, Italy) Moderator : Frank Rasulo (Brescia, Italy) 13:30 - 13:45 - What are the outcomes?Jerry Nolan (Bath, United Kingdom)

13:45 - 14:00 - The impact of gender on post-arrest care Laurie Morrison (Toronto , Canada)

14:00 - 14:15 - Coronary angiographyL Christian Napp (Hannover, Germany)

14:15 - 14:30 - When we need to target a higher arterial pressureMarkus Skrifvars (Helsinki, Finland)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Ventilator managementAri Moskowitz (Boston, United States)

15:00 - 15:15 - Worthwhile or futile to treat seizures after cardiac arrestClifton Callaway (Pittsburgh, United States)

15:15 - 15:30 - Extracerebral organ damage Claudio Sandroni (Rome , Italy)

15:30 - 15:45 - Discussion

15:45 - 16:00 - Don´t ignore the gutDavid Grimaldi (Brussels, Belgium)

16:00 - 16:15 - We need to focus more on cellular metabolismKatherine Berg (Boston, United States)

16:15 - 16:30 - Post-cardiac arrest care: is it cost effective? Markus Skrifvars (Helsinki, Finland)

16:30 - 16:45 - Discussion

Intracranial hypertension: when and how to intervene [Tutorial] 16:50 - 17:20 - Intracranial hypertension: when and how to intervenePeter Le Roux (Wynnewood, United States)

Interesting and unusual echo examinations on critically ill patients [Case discussion] Moderator : Anthony McLean (Sydney , Australia) 17:25 - 18:00 - Interesting and unusual echo examinations on critically ill patientsDaniel De Backer (Brussels, Belgium), Antoine Vieillard–Baron (Boulogne-Billancourt, France), André Denault(Montreal, Canada)

Thursday 17 September 2020 - AM

ROOM : 300 Hall Assessment of thrombocytopenia 2 [Meet the experts] 8:30 - 9:00 - Assessment of thrombocytopeniaManuel Praga (Madrid, Spain), Marlies Ostermann (London , United Kingdom)

9:00 - 9:30 - Break

POCUS as a part of the patient pathway [Simulation Session] Moderator : Adrian Wong (Guilford, United Kingdom) Moderator : Olusegun Olusanya (London, United Kingdom) 9:30 - 10:15 - POCUS as a part of the patient pathwayAntoine Vieillard–Baron (Boulogne-Billancourt, France)

10:15 - 11:15 - Break

Temperature management in SAH patients [Simulation Session] Moderator : Chiara Robba (Genova, Italy) 11:15 - 12:00 - Temperature management in SAH patientsFrank Rasulo (Brescia, Italy)

Thursday 17 September 2020 - PM

ROOM : 300 Hall Temperature management in head trauma [Simulation Session] Moderator : Giuseppe Citerio (Monza, Italy) 13:45 - 14:30 - Temperature management in head traumaGeert Meyfroidt (Leuven , Belgium)

14:30 - 15:00 - Break

Assessment of thrombocytopenia 3 [Meet the experts] 15:00 - 15:30 - Assessment of thrombocytopeniaNicole Juffermans (Amsterdam , Netherlands), Beverley Hunt (London , United Kingdom)

15:30 - 16:15 - Break

Decompensated COPD and NIV failure: what to do? [Simulation Session] Moderator : V Marco Ranieri (Bologna, Italy) 16:15 - 17:00 - Decompensated COPD and NIV failure: what to do?Laurent Papazian (Marseille , France), John Kellum (Pittsburgh, United States)

Thursday 17 September 2020 - AM

ROOM : Arc Room Phenotypes in relation to complex lung disease [Plenary lecture] 8:00 - 8:30 - Phenotypes in relation to complex lung diseaseSally Wenzel (Pittsburgh, United States)

AKI: do we need the acronym? [Round table] Moderator : Ravindra Mehta (La Jolla, United States) 8:35 - 9:15 - AKI: do we need the acronym?Claudio Ronco (Vicenza, Italy), John Kellum (Pittsburgh, United States), Jean-Louis Vincent (Brussels ,Belgium), Heleen Oudemans-Van Straaten (Amsterdam , Netherlands)

Prevention of postoperative complications [Tutorial] 9:20 - 10:00 - Prevention of postoperative complicationsMichael Sander (Giessen, Germany)

After cardiac arrest care (T) [Tutorial] 10:05 - 10:45 - After cardiac arrest careJerry Nolan (Bath, United Kingdom)

Translating ESPEN 2019 guidelines into practice – new algorithm [Tutorial] 10:50 - 11:30 - Nutritional support: my algorithmAnnika Reintam-Blaser (Tartu , Estonia)

Patient – ventilator dyssynchrony [Tutorial] 11:35 - 12:15 - Patient – ventilator dyssynchronyElias N Baedorf Kassis (Boston, United States)

Thursday 17 September 2020 - AM

ROOM : Corner B (Exhibition Area)

Thursday 17 September 2020 - AM

ROOM : Lung House (Exhibition Area)

Thursday 17 September 2020 - PM

ROOM : Lung House (Exhibition Area) Driving pressure and spontaneous breathing during assisted ventilation [Meet the experts] 17:00 - 18:00 - Driving pressure and spontaneous breathing during assisted ventilationGiacomo Bellani (Monza, Italy)

Thursday 17 September 2020 - AM

ROOM : Neuro-Lab (Exhibition Area)

Thursday 17 September 2020 - PM

ROOM : Neuro-Lab (Exhibition Area) Non-invasive neuromonitoring in critically ill patients [Meet the experts] 17:00 - 18:00 - Non-invasive neuromonitoring in critically ill patientsGiuseppe Citerio (Monza, Italy)

Friday 18 September 2020 - AM

ROOM : HLB Room

Friday 18 September 2020 - AM

ROOM : Gold Hall How I manage the ECMO patient [Tutorial] 8:00 - 8:35 - How I manage the ECMO patientEddy Fan (Toronto, Canada)

CPR: How I do it [Tutorial] Moderator : Victoria Metaxa (London, United Kingdom) Moderator : Maximilian Malfertheiner (Regensburg, Germany) 8:40 - 9:15 - CPR: How I do itKatherine Berg (Boston, United States)

Mechanical circulatory support [Tutorial] 9:20 - 9:55 - Mechanical circulatory supporRoberto Lorusso (Maastricht, Netherlands)

Cerebral assessment [Standard presentation] Moderator : Nino Stocchetti (Milan , Italy) Moderator : Niels Martin (Philadelphia, United States) 10:00 - 10:15 - Quantitative pupillometryFabio S. Taccone (Brussels , Belgium)

10:15 - 10:30 - Cerebral oximetry Claudio Sandroni (Rome , Italy)

10:30 - 10:45 - Brain ultrasoundFrank Rasulo (Brescia, Italy)

10:45 - 11:00 - Brain CT to guide management of TBIPeter Le Roux (Wynnewood, United States)

11:00 - 11:15 - Discussion

11:15 - 11:30 - EEG monitoring and outcomes of non brain-injured patients Romain Sonneville (Paris, France)

11:30 - 11:45 - How to assess cerebrovascular autoregulation at the bedside Geert Meyfroidt (Leuven , Belgium)

11:45 - 12:00 - We need to monitor brain oxygenPeter Le Roux (Wynnewood, United States)

12:00 - 12:15 - Can data integration technologies make our lives easier? Victoria McCredie (Toronto, Canada)

12:15 - 12:30 - Discussion

Friday 18 September 2020 - PM

ROOM : Gold Hall Setting PEEP in ARDS [Standard presentation] Moderator : Paolo Pelosi (Genoa , Italy) Moderator : Marcelo Amato (Sao Paulo , Brazil) 13:30 - 13:45 - What we know... and what we don´tNiall Ferguson (Toronto , Canada)

13:45 - 14:00 - Closing the book on the open lung?Jeremy Beitler (New York, United States)

14:00 - 14:15 - I use automated lung recruitment maneuversFernando Suarez Sipmann (Uppsala, Sweden)

14:15 - 14:30 - I look at the chest X rayAlain Mercat (Angers , France)

14:30 - 14:45 - I use IAPManu Malbrain (Brussels, Belgium)

14:45 - 15:00 - Discussion

15:00 - 15:15 - I use EITDiederik Gommers (Rotterdam, Netherlands)

15:15 - 15:30 - I use echoMichel Slama (Amiens , France)

15:30 - 15:45 - I use minimal PEEP in obese patientsPaolo Pelosi (Genoa , Italy)

15:45 - 16:00 - Acute brain injury makes it more complicatedVictoria McCredie (Toronto, Canada)

16:00 - 16:15 - New hope for high PEEP trialsMarcelo Amato (Sao Paulo , Brazil)

16:15 - 16:30 - Discussion

Friday 18 September 2020 - AM

ROOM : Copper Hall VILI [Standard presentation] Moderator : Elias N Baedorf Kassis (Boston, United States) Moderator : Erwan L'Her (Brest, France) 8:00 - 8:15 - Micro-mechanical causes of tissue injuryJohn J Marini (St Paul, United States)

8:15 - 8:30 - Lung-protective ventilation during spontaneous breathingGiacomo Bellani (Monza, Italy)

8:30 - 8:45 - For the same power, the relative effects of tidal volume, PEEP and respiratory rateLuciano Gattinoni (Göttingen, Germany)

8:45 - 9:00 - All you need is driving pressure and respiratory rateMarcelo Amato (Sao Paulo , Brazil)

9:00 - 9:15 - Discussion

9:15 - 9:30 - Targeting plateau and driving pressures is not enoughJohn J Marini (St Paul, United States)

9:30 - 9:45 - Pressure-support is less injurious than pressure-control ventilationPaolo Pelosi (Genoa , Italy)

9:45 - 10:00 - The concept of lung- and diaphragm-protective ventilationEwan Goligher (Toronto, Canada)

10:00 - 10:15 - EIT to visualize hyperinflation at the bedsideDiederik Gommers (Rotterdam, Netherlands)

10:15 - 10:30 - Discussion

Abdominal compartment syndrome [Tutorial] 10:35 - 11:10 - Abdominal compartment syndromeManu Malbrain (Brussels, Belgium)

Acid-base and electrolytes [Tutorial] 11:15 - 11:50 - Acid-base and electrolytesNiels Van Regenmortel (Antwerp, Belgium)

Management of the organ donor [Tutorial] 11:55 - 12:30 - Management of the organ donorEric Hoste (Ghent , Belgium)

Friday 18 September 2020 - PM

ROOM : Copper Hall Intraabdominal issues [Standard presentation] Moderator : Jan De Waele (Ghent , Belgium) Moderator : Daniel De Backer (Brussels, Belgium) 13:45 - 14:00 - How do we protect the gut in critical illness?Craig M Coopersmith (Atlanta, United States)

14:00 - 14:15 - Stress ulcer prophylaxis revisitedAnnika Reintam-Blaser (Tartu , Estonia)

14:15 - 14:30 - Necrotizing pancreatitisPierre–François Laterre (Brussels , Belgium)

14:30 - 14:45 - Discussion

14:45 - 15:00 - Please don´t rest the pancreas!Elisabeth De Waele (Brussels, Belgium)

15:00 - 15:15 - When to measure intraabdominal pressure... and when to treat?Annika Reintam-Blaser (Tartu , Estonia)

15:15 - 15:30 - There are new ways to measure abdominal pressureManu Malbrain (Brussels, Belgium)

15:30 - 15:45 - What´s new in open abdomen managementJan De Waele (Ghent , Belgium)

15:45 - 16:00 - Discussion

Friday 18 September 2020 - AM

ROOM : Salle M (Bozar)

Friday 18 September 2020 - AM

ROOM : Tent Delirium [Standard presentation] Moderator : Alain Mercat (Angers , France) Moderator : Philipp Lepper (Homburg, Germany) 8:00 - 8:15 - The gut-brain connection and the “psychobiome”Paul Wischmeyer (Durham, United States)

8:15 - 8:30 - How to reduce the burden of deliriumE Wesley Ely (Nashville, United States)

8:30 - 8:45 - Is minimal cognitive deficit a cause for poor outcome from ICU delirium?Ivor Douglas (Denver, United States)

8:45 - 9:00 - Discussion

9:00 - 9:15 - An ounce of prevention is better than a pound of curesDetlef Kindgen–Milles (Düsseldorf , Germany)

9:15 - 9:30 - Alcohol withdrawal in the ICUOlivier Huet (Brest, France)

9:30 - 9:45 - You should give alcohol to anyone who needs itJan Bakker (New York, United States)

9:45 - 10:00 - Discussion

10:00 - 10:15 - Break

Right heart dysfunction [Standard presentation] Moderator : Fernando Suarez Sipmann (Uppsala, Sweden) Moderator : Jean-Christophe Richard (Angers, France) 10:15 - 10:30 - Right ventricular physiology and adaptation Michael R. Pinsky (Pittsburgh, United States)

10:30 - 10:45 - Heart-lung interactions in ARDSXavier Monnet (Le Kremlin-Bicêtre , France)

10:45 - 11:00 - I like to monitor right ventricular pressureAndré Denault (Montreal, Canada)

11:00 - 11:15 - Discussion

11:15 - 11:30 - Right heart failure revisitedPhilipp Lepper (Homburg, Germany)

11:30 - 11:45 - Practical implicationsAntoine Vieillard–Baron (Boulogne-Billancourt, France)

11:45 - 12:00 - Discussion

How I set up the respirator [Tutorial] 12:00 - 12:35 - How I set up the respiratorAlain Mercat (Angers , France)

Friday 18 September 2020 - AM

ROOM : Silver Hall ECMO: socio-ethical aspects [Standard presentation] Moderator : Elie Azoulay (Paris , France) Moderator : Niall Ferguson (Toronto , Canada) 8:00 - 8:15 - This patient has been on ECMO for two weeks: should I give up?Maximilian Malfertheiner (Regensburg, Germany)

8:15 - 8:30 - Quality of life of ARDS survivorsLaurent Papazian (Marseille , France)

8:30 - 8:45 - Bridge to heal, bridge to transplant or bridge to nowhereMichael Quintel (Göttingen , Germany)

8:45 - 9:00 - Discussion

9:00 - 9:15 - The challenging aspects of ECPRL Christian Napp (Hannover, Germany)

9:15 - 9:30 - ECMO is overusedDaniel Talmor (Boston , United States)

9:30 - 9:45 - The media may influence the use of ECMO?Daniel Brodie (New York, United States)

9:45 - 10:00 - Discussion

Organ donation [Standard presentation] Moderator : J Randall Curtis (Seattle, United States) Moderator : Victoria Metaxa (London, United Kingdom) 10:00 - 10:15 - Organ donation after cardiac death Laurie Morrison (Toronto , Canada)

10:15 - 10:30 - Organ donation after ECPR: should we do it?Dwight Bailey (Charlotte, United States)

10:30 - 10:45 - Management of the organ donorEric Hoste (Ghent , Belgium)

10:45 - 11:00 - Discussion

11:00 - 11:15 - Death after organ donation: an ethical conversationE Wesley Ely (Nashville, United States)

11:15 - 11:30 - What about donation after euthanasia?Jacques Creteur (Brussels , Belgium)

11:30 - 11:45 - Discussion

Coagulation disorders [Tutorial] 11:50 - 12:25 - Coagulation disordersDietmar Fries (Innsbruck, Austria)

Friday 18 September 2020 - PM

ROOM : Silver Hall Traumatic brain injury [Tutorial] 13:30 - 14:05 - Traumatic brain injuryAndrea Lavinio (Cambridge , United Kingdom)

The patient with cancer [Standard presentation] Moderator : Victoria Metaxa (London, United Kingdom) Moderator : Maximilian Malfertheiner (Regensburg, Germany) 14:10 - 14:25 - The specific aspects of renal failureMarlies Ostermann (London , United Kingdom)

14:25 - 14:40 - Cancer and sepsisCraig M Coopersmith (Atlanta, United States)

14:40 - 14:55 - CAR-T cell therapyElie Azoulay (Paris , France)

14:55 - 15:10 - Discussion

15:10 - 15:25 - Checkpoint inhibitorsMaximilian Malfertheiner (Regensburg, Germany)

15:25 - 15:40 - Toxicities associated with targeted therapies and immunotherapyStephen M Pastores (New York, United States)

15:40 - 15:55 - Differences between these treatmentsVictoria Metaxa (London, United Kingdom)

15:55 - 16:10 - Discussion

Friday 18 September 2020 - AM

ROOM : 100 Hall Cardiovascular (patho)physiology: the basics [Standard presentation] Moderator : Frank van Haren (Canberra, Australia) Moderator : Daniel De Backer (Brussels, Belgium) 8:00 - 8:15 - Physiology of systemic venous returnAntoine Vieillard–Baron (Boulogne-Billancourt, France)

8:15 - 8:30 - From Frank-Starling to GuytonXavier Monnet (Le Kremlin-Bicêtre , France)

8:30 - 8:45 - The revised Starling principle adds complexityRobert G Hahn (Södertälje, Sweden)

8:45 - 9:00 - The importance of venous congestionAndré Denault (Montreal, Canada)

9:00 - 9:15 - Discussion

9:15 - 9:30 - New views on the hemodynamic effects of high PEEPMichel Slama (Amiens , France)

9:30 - 9:45 - The hemodynamic influence of abdominal pressureManu Malbrain (Brussels, Belgium)

9:45 - 10:00 - Oxygen delivery in sepsis: where do we stand now?Guillermo Gutierrez (Washington, United States)

10:00 - 10:15 - Discussion

10:15 - 10:30 - Break

Facing an emergency [Standard presentation] Moderator : Wesley Self (Nashville, United States) Moderator : Heatherlee Bailey (Durham, United States) 10:30 - 10:45 - This patient is bleeding from severe post-partum hemorrhageBeverley Hunt (London , United Kingdom)

10:45 - 11:00 - This patient is perhaps having seizuresPaul Vespa (Los Angeles , United States)

11:00 - 11:15 - This patient has hyponatremia of 110 mmol/LCarole Ichai (Nice, France)

11:15 - 11:30 - Discussion

11:30 - 11:45 - This patient has a hypertensive crisisPieter Van Paassen (Maastricht, Netherlands)

11:45 - 12:00 - This patient has anaphylactic shockJerrold H Levy (Durham, United States)

12:00 - 12:15 - This patient just aspirated: now what?Michael S Niederman (New York, United States)

12:15 - 12:30 - Discussion

Friday 18 September 2020 - PM

ROOM : 100 Hall End-of-life issues [Standard presentation] Moderator : Jacques Creteur (Brussels , Belgium) Moderator : Geert Meyfroidt (Leuven , Belgium) 13:30 - 13:45 - Advanced decision making in the ICUVictoria Metaxa (London, United Kingdom)

13:45 - 14:00 - What about ReSPECT for some?Gavin Perkins (Warwick, United Kingdom)

14:00 - 14:15 - What is the ´right` intensity of care at the end of life?J Randall Curtis (Seattle, United States)

14:15 - 14:30 - Discussion

14:30 - 14:45 - We should avoid shopping listsJan Bakker (New York, United States)

14:45 - 15:00 - Difficult decisions in the very elderly patientFrank van Haren (Canberra, Australia)

15:00 - 15:15 - Difficult decisions in complex surgical patientsNiels Martin (Philadelphia, United States)

15:15 - 15:30 - Discussion

15:30 - 15:45 - When doctors and families disagreeKatherine Berg (Boston, United States)

15:45 - 16:00 - Moral distress among residents facing end-of-life care decisionsDaryl Jones (Heidelberg, Australia)

16:00 - 16:15 - How to involve the teamJacques Creteur (Brussels , Belgium)

16:15 - 16:30 - Discussion

Friday 18 September 2020 - AM

ROOM : Terarken (BOZAR) Guidelines: progress and pitfalls [Standard presentation] Moderator : Flavia Machado (Sao Paulo , Brazil) Moderator : Annika Reintam-Blaser (Tartu , Estonia) 8:00 - 8:15 - In nutritionMichaël Casaer (Leuven, Belgium)

8:15 - 8:30 - In neurocritical careVictoria McCredie (Toronto, Canada)

8:30 - 8:45 - In burnsMichael Reade (Brisbane, Australia)

8:45 - 9:00 - Discussion

9:00 - 9:15 - In sepsisJean-Louis Teboul (Le Kremlin-Bicêtre, France)

9:15 - 9:30 - In pneumoniaMichael S Niederman (New York, United States)

9:30 - 9:45 - In cardiac arrestClifton Callaway (Pittsburgh, United States)

9:45 - 10:00 - Discussion

The quick 5 min clinical evaluation [Standard presentation] Moderator : Arthur van Zanten (Ede, Netherlands) Moderator : Bruno François ( Limoges , France) 10:00 - 10:15 - The cardiovascular evaluationMaurizio Cecconi (Rozzano, MI, Italy)

10:15 - 10:30 - The cardiopulmonary evaluationJohn J Marini (St Paul, United States)

10:30 - 10:45 - The neurological evaluationMauro Oddo (Lausanne , Switzerland)

10:45 - 11:00 - Whole body ultrasound as a complementOlusegun Olusanya (London, United Kingdom)

11:00 - 11:15 - Discussion

Decompensated COPD [Tutorial] 11:20 - 11:50 - Decompensated COPDGuillermo Gutierrez (Washington, United States)

Everything you want to know about statistical methods [Tutorial] 11:55 - 12:25 - Everything you want to know about statistical methodsLars Wiuff Andersen (Aarhus, Denmark)

Friday 18 September 2020 - AM

ROOM : 400 Hall ICU design and organization [Standard presentation] Moderator : Craig M Coopersmith (Atlanta, United States) Moderator : Leo Heunks (Amsterdam, Netherlands) 8:00 - 8:15 - ICU design: the good, the bad and the uglyPhilip Hopkins (London, United Kingdom)

8:15 - 8:30 - My ICU is the nicest Diederik Gommers (Rotterdam, Netherlands)

8:30 - 8:45 - The environmental burden of ICU care Niklas Nielsen (Helsingborg, Sweden)

8:45 - 9:00 - Discussion

9:00 - 9:15 - Providing safetyAdrian Wong (Guilford, United Kingdom)

9:15 - 9:30 - Who should get the last ICU bed? The postoperative patient?Michael Sander (Giessen, Germany)

9:30 - 9:45 - The perfect ICU organizationJacques Creteur (Brussels , Belgium)

9:45 - 10:00 - Discussion

10:00 - 10:15 - Break

Rapid response systems [Standard presentation] Moderator : Katherine Berg (Boston, United States) Moderator : Marlies Ostermann (London , United Kingdom) 10:15 - 10:30 - Early identification of sepsis on the hospital floorMassimo Girardis (Modena , Italy)

10:30 - 10:45 - Can we predict who will have a rapid response call?Daryl Jones (Heidelberg, Australia)

10:45 - 11:00 - Discussion

11:00 - 11:15 - How to evaluate itJonathan Bannard–Smith (Manchester, United Kingdom)

11:15 - 11:30 - Wireless wearables on the wards: the new WWW revolutionFrédéric Michard (Lausanne, Switzerland)

11:30 - 11:45 - Big data can help to evaluate the risks of decompensationMichael R. Pinsky (Pittsburgh, United States)

11:45 - 12:00 - Discussion

How to set up your rapid response system [Tutorial] 12:00 - 12:30 - How to set up your rapid response system Jonathan Bannard–Smith (Manchester, United Kingdom)

Friday 18 September 2020 - PM

ROOM : 400 Hall Respiratory muscle fatigue [Standard presentation] Moderator : Philip Hopkins (London, United Kingdom) Moderator : Tom Schepens (Edegem, Belgium) 13:30 - 13:45 - The important role of expiratory musclesLeo Heunks (Amsterdam, Netherlands)

13:45 - 14:00 - Expiratory activity in patients with ARDS Elias N Baedorf Kassis (Boston, United States)

14:00 - 14:15 - Keeping spontaneous ventilation from the startJean-Christophe Richard (Angers, France)

14:15 - 14:25 - Discussion

14:25 - 14:40 - Spontaneous breathing: how (and why) to measure patient effortsNiall Ferguson (Toronto , Canada)

14:40 - 14:55 - Making sense of APRVDaniel Talmor (Boston , United States)

14:55 - 15:10 - Spontaneously breathing: the value of dynamic parameters Azriel Perel (Tel Aviv , Israel)

15:10 - 15:20 - Discussion

15:20 - 15:35 - Making sense of NAVAPhilip Hopkins (London, United Kingdom)

15:35 - 15:50 - NAVA and EAdi: what do they add? Giacomo Bellani (Monza, Italy)

15:50 - 16:05 - Protecting lung and diaphragm in ARDSTom Schepens (Edegem, Belgium)

16:05 - 16:20 - Role of ultrasound to facilitate diaphragm-protective mechanical ventilationLeo Heunks (Amsterdam, Netherlands)

16:20 - 16:35 - Discussion

Friday 18 September 2020 - AM

ROOM : Panoramic Hall Neurological outcomes after cardiac arrest [Standard presentation] Moderator : Stephen M Pastores (New York, United States) Moderator : Ari Moskowitz (Boston, United States) 8:00 - 8:15 - A critical literature reviewClifton Callaway (Pittsburgh, United States)

8:15 - 8:30 - Automated pupillometryFabio S. Taccone (Brussels , Belgium)

8:30 - 8:45 - How does brain imaging help? Lionel Velly (Marseille , France)

8:45 - 9:00 - Discussion

9:00 - 9:15 - Do biomarkers help?Markus Skrifvars (Helsinki, Finland)

9:15 - 9:30 - Can we predict late awakening?Mauro Oddo (Lausanne , Switzerland)

9:30 - 9:45 - Can we also predict good outcomes?Claudio Sandroni (Rome , Italy)

9:45 - 10:00 - Discussion

10:00 - 10:15 - Use of gases for cerebral protection Mark Dunn (Edinburgh, United Kingdom)

10:15 - 10:30 - Stimulating the brain after comaSteven Laureys (Liège , Belgium)

10:30 - 10:45 - Quality of life mattersLaurie Morrison (Toronto , Canada)

10:45 - 11:00 - Discussion

Initial management of polytrauma [Tutorial] 11:05 - 11:40 - Initial management of polytraumaMarc Maegele (Cologne , Germany)

ICU delirium [Tutorial] 11:45 - 12:20 - ICU deliriumE Wesley Ely (Nashville, United States)

Friday 18 September 2020 - PM

ROOM : Panoramic Hall Encephalitis [Tutorial] 13:30 - 14:00 - EncephalitisRomain Sonneville (Paris, France)

In the emergency room [Standard presentation] Moderator : Adrian Wong (Guilford, United Kingdom) Moderator : Wesley Self (Nashville, United States) 14:05 - 14:20 - Toxidromes and unusual intoxicantsHeatherlee Bailey (Durham, United States)

14:20 - 14:35 - Severe community-acquired pneumoniaWesley Self (Nashville, United States)

14:35 - 14:50 - Sepsis in the ED: issues and opportunitiesFlavia Machado (Sao Paulo , Brazil)

14:50 - 15:05 - Discussion

15:05 - 15:20 - Clinical and/or biomarker approach to identify sepsisBruno François ( Limoges , France)

15:20 - 15:35 - Rapid ultrasound for the whole bodyAdrian Wong (Guilford, United Kingdom)

15:35 - 15:50 - Rapid ultrasound for the brain Chiara Robba (Genova, Italy)

15:50 - 16:05 - Some patients stay there for too long Heatherlee Bailey (Durham, United States)

16:05 - 16:20 - Discussion

Friday 18 September 2020 - AM

ROOM : Studio Room Transfusion strategies [Standard presentation] Moderator : Gavin Perkins (Warwick, United Kingdom) Moderator : Chiara Robba (Genova, Italy) 8:00 - 8:15 - Pathophysiology and consequences of red cell transfusionKeyvan Karkouti (Toronto, Canada)

8:15 - 8:30 - Massive transfusion after traumaPierre Bouzat (Grenoble, France)

8:30 - 8:45 - A standard 70 g/L hemoglobin threshold is bad practiceTimothy Walsh (Edinburgh , United Kingdom)

8:45 - 9:00 - Discussion

9:00 - 9:15 - Not just a Hb level, please!Ludhmila Hajjar (Sao Paulo, Brazil)

9:15 - 9:30 - When to transfuse the brain injured patientPeter Le Roux (Wynnewood, United States)

9:30 - 9:45 - Any place for iron therapy?Sigismond Lasocki (Angers, France)

9:45 - 10:00 - Discussion

Pediatric respiratory support [Tutorial] 10:05 - 10:40 - Pediatric respiratory supportTom Schepens (Edegem, Belgium)

Weaning from invasive ventilation [Tutorial] 10:45 - 11:20 - Weaning from invasive ventilationGavin Perkins (Warwick, United Kingdom)

Refeeding syndrome [Tutorial] 11:25 - 12:00 - Refeeding syndromeArthur van Zanten (Ede, Netherlands)

Preparing for the next pandemic [Round table] 12:05 - 12:45 - Preparing for the next pandemic

Friday 18 September 2020 - AM

ROOM : 300 Hall

Friday 18 September 2020 - AM

ROOM : Arc Room

Friday 18 September 2020 - AM

ROOM : Corner B (Exhibition Area)

Friday 18 September 2020 - AM

ROOM : Lung House (Exhibition Area)

Friday 18 September 2020 - AM

ROOM : Neuro-Lab (Exhibition Area)