Mitsubishi Tanabe Pharma Corporation Medium-Term Management Plan … · 2010-03-31 · Basic...
Transcript of Mitsubishi Tanabe Pharma Corporation Medium-Term Management Plan … · 2010-03-31 · Basic...
Mitsubishi Tanabe Pharma Corporation Medium-Term Management Plan 08-10Dynamic Synergy for 2015
President Representative DirectorNatsuki Hayama
May 9,2008
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Agenda
Ⅰ. Basic Policies of Medium-Term Management Plan 08-10
Ⅱ. Fiscal 2015 Objectives and Growth Path
Ⅴ. Summary
Ⅲ. Fiscal 2010 Numerical Targets
Ⅳ. 2008-2010 Medium-Term Issues and Action Plans
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Basic Policies of Medium-Term Management Plan 08-10
Medium-TermManagement Plan
08-10
Fiscal 2015Objectives
PositioningFormulated as Three-Year Implementation PlanTargeting the Achievement of Fiscal 2015Objectives and the Realization of the Vision
Key Concept -VisionMitsubishi Tanabe Pharma takes on the challenge of making
Dynamic Synergy a reality. To the Company, Dynamic Synergy means makingfull use of abundant management resources, bringing together the expertise andenergy of all directors, officers and employees throughout the Company, andcreating new business domains and business models.
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Fiscal 2015 Objectives and Growth Path
New Growth Drivers for Fiscal 2015
Fiscal 2015 Objectives
Product Strategy Targeting the Fiscal 2015 Objectives
Establishment of a Competitive Edge
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Fiscal 2015 Objectives -Working to Become a Global, Research-Driven Pharmaceutical Company-
Establish a R&D pipeline capable of launchingone product every two years,with a focus on the metabolic and circulatory disease areas
Establish a top level position in the domestic ethical drug marketby launching and cultivating major products
Establish in-house sales structure in the U.S. andachieve overseas sales of more than ¥100 billion
Establish competitive superiority through the creation ofdifferentiated business models
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Product Strategy Targeting the Fiscal 2015 Objectives
Focused therapeutic areas
U.S./Europe Japan
Strategic Alliances
Implement strategic alliances to accelerate the above strategies
・Rapidly acquire approval for 2 productsin renal field; build and strengthenin-house sales structure
・Operations in diabetes though licensing,co-development and co-promotions, etc.
・Establish products pipeline in diabetes area・Maximize value of core products through LCM(bolster franchises in RA and stroke areas.)
Metabolic and circulatory to be positioned as “High Priority Field” in R&D → Diabetes and Stroke: Highest Priority diseases (pursue total disease care)
・
Diabetes: metabolic risk (obesity/dyslipidemia)~complications (kidney disease, dialysis)・Stroke: acute phase~convalescence~maintenance
RA: Rheumatoid Arthritis
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New Growth Drivers for Fiscal 2015
Overseas pharmaceutical sales:more than ¥100 billion
Metabolism and circulatory fields
MCI-196(Hyperphosphatemia)
MP-146(Chronic kidney disease)
MP-513(Type 2 diabetes)
MP-513
MP-424(Chronic hepatitis C)
FTY720(Multiple Sclerosis)
TA-7284
TA-7284(Diabetes)
Launch and the cultivate major productsin domestic market
Fiscal 2010
Fiscal 2015
・・In-house developmentin the U.S. and Europe
・・In-house developmentin Japan
・・Licensing,joint developmentin the U.S and Europe
Remicade Radicut
Anplag Talion
Urso Tanatril
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Targeting the Establishment of a Competitive Edge
Marketing
CMC
Development Production
Research Reliabilityguaranteed
BiomarkersFundamental technologies fordrug discoveryBiotechnologies
MitsubishiChemicalHoldings
Group
Generics:Tanabe SeiyakuHanbai Co., Ltd.
Remicade
Anplag Talion Urso
Tanatril
Cerebral fieldRadicut
NovastanGrtpa
Vaccines
Plasmap heresis
BenesisCorporation
Psychiatricfield
Yoshitomiyakuhin Corporation
Narcotic
OTC
Aiming to build a businessmodel that fully utilizesmanagement resources
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Promoting personalized medicine
Moleculence Corporation: biomarker discoveryMitsubishi Chemical Group Science andTechnology Research Center;Development of analyticaltechnologies
Mitsubishi Chemical Mitsubishi Chemical MedienceMedience;Development of diagnostic agents
Biomarker discovery
Stroke-related marker discoveryParticipation in Japan Pharmacogenomics Consortium(JPGC) databaseDiabetes-related marker discovery
LCM utilizing biomarkers
Drug discovery utilizing biomarkers
Medway:Avoiding adverse reactionsin pichia pastoris IgE antibody positive patients
Realizing targeted medicine
Increase satisfactionwith medical care
through the realization ofpersonalized medicine
Alliances with Mitsubishi ChemicalHoldings Group Companies
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Fiscal 2010 Numerical Objectives
Fiscal 2010 Numerical Targets
Sales Objectives for Domestic Pharmaceutical Operations
Trends in Profit and Cost Structures
Policies for Returning Profits
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Fiscal 2010 Numerical Targets
(Consolidated) Fiscal 2007(actual)*
Fiscal 2010(targets)
Net sales 4,094 4,600Operating income 725 950
Net income 319 560R&D expenses 723 820
Unit: ¥100 million
*Fiscal 2007 figures are simple sums
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Fiscal 2010 Numerical Targets (Comparison with Figures Announced May 2007)
(Consolidated)Fiscal 2010 Numerical TargetsMedium-Term
Management Plan 08-10
AnnouncedMay 2007
Net sales 4,600 4,800Operating income 950 1,000
Net Income 560 600R&D expenses 820 870
Number of employees 9,400employees
9,400employees
Cost Synergies 240 200
Unit: ¥100 million
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Sales targets for domestic pharmaceutical operations
Domesticfocus:
6 drugs
Domesticfocus:
6 drugs
Other domestic
drugs
Unit: ¥100 million3,900
2,230(△76)
1,460(+346)
*Fiscal 2007 figures are simple sums
RemicadeRadicutAnplagUrsoTarionTanatril
500300220200140100
3,514
2,306
1,114
Fiscal 2007 (actual) Fiscal 2010 (targets)
Generic drugsOTC drugs
14070
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% of net sales
R&D expenses
Trends in profit and cost structures
+ 3.0 percentage points
+ 0.1 percentage points
Operating income
Cost of sales
4,600
950
820
1,770
1,060
4,094725
723
1,505
1,141 SG&A(excluding R&D expenditures)
+ 1.7 percentage points
- 4.9 percentage points
Fiscal 2007 (actual) Fiscal 2010 (target)
*Fiscal 2007 figures are simple sums Unit: ¥100 million
(20.7%)
(17.8%)
(38.5%)
(23.0%)
(17.7%)
(17.7%)
(36.8%)
(27.9%)
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Policies for returning profits
More aggressivereturn of profits
■ Objective for the consolidated dividend payout ratio is 35%(prior to amortization of goodwill), and over long term we will work to providea more aggressive return to shareholders.
¥24
29.1%33.2%
Fiscal 2006 Fiscal 2007 Fiscal 2008 (forecast)
Dividend payout ratio
Cash dividends
Targets35.0%
¥26¥28
*Tanabe Seiyaku‘s interim figures and Mitsubishi Tanabe Pharma’s estimated year-end figures are used for the FY 2007 dividends. The dividend payout ratio is calculated exclusive of the amortization of goodwill and provision for reserve for HCV litigation from Mitsubishi Tanabe Pharma's second-half net income, and with estimated year-end dividends.
32.1%
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Key Management Issues and the Action Plan for the 08-10 Medium-Term Period
Enhancing Our Presence in Domestic Marketing
Steady Progress in Key Development Projects
Progress in Developing Overseas Pharmaceutical Operations
Progress in Generic Operations
Creating an Efficient Organization and Cost Structure
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Enhancing our presence in domestic marketing
Maximizing the Product value of Remicade
・Change in RA usages/dosages・Additional indications
- Psoriasis, and ankylosing spondylitis, ulcerative colitis・Increase in Remicade specialist
Increasing specialized knowledge in cerebral field
Promotion system (unification of sales lines) Strength Group marketing cooperation
・Increase in specialist in stroke field・Market expansion (opportunity)
-Increase in number of patients (about 2% a year)-Reimbursement incentives for stroke treatment extending from hyperacute phase to convalescence
・Promote use of our products at each phase -Hyperacute phase (Grtpa)-Acute phase (Radicut / Novastan)-Chronic phase (Sermion)
・Cooperation between MRs responsible foreach institution and specialists
・Hospital sales channel:Overlapping by department- Responsbility centered on internal medicine (Primary-MR)- Responsibility centered on surgery (Acute-MR)
・General practitioner sales channel:Introduce system of overlapping MRresponsibility by area
・Yoshitomiyakuhin Corporation(Psychiatric field)
・Benesis Corporation (Plasma fraction preparations)-Consider integrated production sales systems
・Tanabe Seiyaku Hanbai Co., Ltd. (Generic drugs)
Maximize marketing synergies
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Maximizing the Product Value of Remicade
Specialists
LCM
Increase in number of Specialists Improving quality
Change inRA usages/dosages
Psoriasis
RA: Rheumatoid ArthritisCD: Crohn's Disease(¥100 million)
RA
CDCD
Other
RA
CDCDOther
500
400
100
200
0
300
Fiscal 2007 (actual) Fiscal 2010 (target)
Ulcerative Colitis
Ankylosing Spondylitis
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Market potential of biological agents in RA market
Fiscal 2010 (forecast)
60
40
20
Fiscal 2007
100%
80
Remicade:about 1/3
JapanU.S.
Adoption of biological agents(% of RA patients receiving)
Other biological
agents
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Steady progress in phase III
Steady progress in key development projects
Medium-Term Management PlanMedium-Term Management Plan
U.S.and
Europe
MI-196 (Hyperphosphatemia)
MP-146 (Chronic kidney disease)
Targeting NDA by fiscal 2010
20102008 2009
Alliances anticipated in U.S. and EuropeDomestic
MP-424 (Chronic hepatitis C)
MP-513 (Type 2 diabetes)
Steady progress
Licensed outU.S. and Europe TA-7284 (Diabetes)
LCM
RA/-Change in usages/dosages
Psoriasis
Ankylosing Spondylitis
Ulcerative Colitis
ALS
Remicade
Radicut
2015
Approval
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Progress in Developing Overseas Pharmaceutical Operations
Prepare in-house sales system in the U.S. andEurope for MCI-196 and MP-146
Targeting initial in-house salesin the U.S.,
start to establish salesfoundation
Targeting concurrent salesin Europe as well,
establish sales foundation(Use existing Argatroban
sales foundation)
Start pre-marketing activitiesfor nephrologists anddialysis specialists,
which will bethe target of promotions
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Progress in Developing Overseas Pharmaceutical Operations
Drug sales in Asia
Progress in sales operations in Asia
Make full use of operational foundationin each country and expand productssold through in-house system,thereby advancing pharmaceutical operations
Fiscal 2007(actual)
Fiscal 2010(target)
(¥100 million)
200
100
0
Tianjin Tanabe Seiyaku Co., Ltd.
Tai Tien Pharmaceuticals Co.,Ltd.
Taiwan Tanabe Seiyaku Co.,Ltd.
P.T. Tanabe Indonesia
Welfide Korea Co., Ltd.
Mitsubishi Pharma(Guangzhou) Co., Ltd.
Increase the number of MRs from 500 to 600.
Mitsubishi Pharma Research &Development (Beijing) Co., Ltd.
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Progress in generic operations
Net sales: ¥14.0 billionNumber of ingredients: 100
Alliances
Rapid realization
Strategic alliances
Mitsubishi Tanabe Pharma CorporationR&D system, drug consultation center, PMS system, quality assurance system
Marketing systemEstablishment of Tanabe Seiyaku Hanbai Co., Ltd. in April 2008(100 person system)
Bolster tie-ups with distributors→development of health insurance pharmacies / DPC hospitals
Fiscal 2008 Fiscal 2010
Net sales: ¥3.7 billionNumber of products: 14
Internal medicines (solid)
Reliable genericssupply system
Enhance lineup / Bolster marketing (marketing consolidation)
Fiscal 2007
Net sales: ¥5.9 billionNumber of products: 25
Bolster lineup of injectable formulationsBolster lineup of injectable formulations
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Creating an efficient organization and cost structure
Fiscal 2008 Fiscal 2010 Fiscal 2015Time schedule (plan)
Baseconsolidation
Reorganize subsidiariesand affiliates
Ensuring an optimallysized workforce
Cost reductions
Head office
Research facilities
Other
◆Osaka head office building consolidation◆Tokyo head office building consolidation
◆Relocate research facilities currently in Hirakata Office
◆In stages, consolidate research facilitiesinto two bases, one in Kanto and one in Kansai
◆Consolidate Nabari training centers
◆Consolidate distribution facilities
Reorganize and consolidate production bases
◆Consolidate production companies(MP-Technopharma Corporation,
Tanabe Seiyaku Yamaguchi Co., Ltd.)◆Consolidate service companies(Tanabe Total Service Co., Ltd.,
Welfide Service Corporation)
◆Consolidation pensions, integrate personnel systems◆Fiscal 2010 objective: 9,400 employees(10,491 at time of merger)
◆Early retirement system
Establish Medium-Term Management Plan 08-10 Follow Up Committee, Work to efficient organization and cost structure
◆Fiscal 2010 cost synergies from reducing all types of expenses and consolidating bases: ¥24.0 billion
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Medium-Term Management Plan 08-10 Follow Up Committee
2008-2010 Medium-Term Issues
Summary
Enhancing our presence in domestic marketing
Progress in key development projects
Progress in overseas pharmaceutical operations
Progress in generic drug business
Establish efficient organization and cost structures
Bolster pipeline for metabolism and circulatory fields
Launch and cultivate major domestic drugs
Business model with competitive edge
Establish in-house sales system in the U.S.and achieve overseas drug sales
of more than ¥100 billion
Fiscal 2015 Objectives
We strive to be a global research-drivenpharmaceutical company
that is trusted by communities.
Forward-looking statements
All of the forward-looking statements in these materialsare the judgments of the Companyin accordance with certain subjective assumptions andbased on information currently available to management.Future results may differ materially due to any of a number of factors.