Mitral stenosis
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Transcript of Mitral stenosis
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MITRAL STENOSISK. Kavindya M. Fernando
JMJ 1
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Mitral stenosis• Mitral valve– Consist of fibrous annulus,– Anterior & posterior leaflets– Chordae tendinae,– Papillary muscle
JMJ 2
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Mitral stenosis• Commonest cause :rheumatic heart
disease• Infections with group A beta hemolytic
streptococci• More common in women
• Inflammation leads to commissural fusion and a reduction in mitral valve orifice area
JMJ 3
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JMJ 4
Pathophysiology• Normal valve area: 4-6 cm2
• Mild mitral stenosis: –MVA 1.5-2.5 cm2
–Minimal symptoms• Moderate mitral stenosis–MVA 1.0-1.5 cm2 usually does not
produce symptoms at rest• Severe mitral stenosis–MVA < 1.0 cm2
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To maintain sufficient cardiac output
1. Left arterial pressure increases2. Left arterial hypertrophy and dilation
3. Pulmonary veins, pulmonary arterial and R/ heart pressure increases
4. Increase of pulmonary capillary pressure 5. Followed by development of
– pulmonary oedema– Atrial fibrillation with tachycardia– Loss of coordinated atrial contraction
JMJ 5
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To maintain sufficient cardiac output
6. This is prevented by (Reactive pulmonary hypertension)– Alveolar and capillary thickening– Pulmonary arterial vasoconstriction
7. Pulmonary hypertension leads to– R/ ventricular hypertrophy, dilation and
failure with subsequent tricuspid regurgitation
JMJ 6
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Symptoms
• Palpitation• Systemic emboli
JMJ 7
• Dyspnoea• Pulmonary
infections (Recurrent bronchitis)
• Haemoptysis• Cough• R/ heart failure• Fatigue• Abdominal and
lower limb swelling
Atrial fibrillation Pulmonary Hypertension
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Signs• Face : Mitral fascies• Pulse : atrial fibrillation• RV : Heaving, sustained• Apex: Localized, tapping• Sounds: Loud S1, Loud P2 (if
pulmonary hypertension), opening snap• Murmurs: Mid diastolic rumble at
apex
JMJ 8
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Mitral Stenosis: Physical Exam
• First heart sound (S1) is accentuated & snapping• Opening snap (OS) after aortic valve closure• Low pitch diastolic rumble at the apex• Pre-systolic accentuation (esp. if in sinus rhythm)
S1 S2 OS S1
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Signs (Face)• Severe mitral stenosis with pulmonary
hypertension• Mitral fascies / malar rash
• Bilateral• Cyanotic or dusky pink
discolouration• Over the upper cheeks• Due to atriovenous anastomosis &• Vascular stasis
JMJ 10
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Signs (Pulse)• Small volume pulse• Usually regular in early stages,• If the patient is in sinus rhythem
• In severe disease, may develop atrial fibrillation
• Irregularly irregular pulse
JMJ 11
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Signs (Jugular Veins)• If R heart failure develops
• obvious distension of jugular veins
• If pulmonary hypertension or tricuspid stenosis is present
• ‘a’ Wave will be prominent
JMJ 12
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Signs (Palpation)• Tapping impulse felt parasternally on
left side• Palpable 1st heart sound • Combined with left ventricular backward
displacement• Produced by an enlarging left ventricle
• Sustained parasternal impulse• Due to R ventricular hypertrophy
JMJ 13
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Signs (Auscultation)• Loud 1st heart sound
– If the mitral valve is pliable– It will not occur in calcified mitral stenosis
• Opening snap– Valve suddenly opens with the force of the increased
L arterial pressure
• Low pitched ‘rumbling’ mid diastolic murmur– Best heard with bell held lightly– At the apex with the patient lying on the left side
JMJ 14
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Signs (Auscultation)• If the patient is in sinus rhythm–Murmur becomes louder at the end of
diastole– As a result of atrial contraction
– (Pre- systolic accentuation)
JMJ 15
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How to determine the severity of mitral stenosis
• Presence of pulmonary hypertension
– Recognized by R/ ventricular heave & loud pulmonary component of 2nd heart sound
– And signs with R heart failure : Oedema, hepatomegaly
– Graham Steell murmurJMJ 16
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How to determine the severity of mitral stenosis
• Closeness of the opening snap to the 2nd heart sound ∞ severe MS
• Length of mid-diastolic murmur ∞ severity
• As the valve cusps become immobile– Loud 1st heart sound softens– Opening snap diasppears– When pulmonary hypertension occurs : P2 intensity
increase, mid diastolic murmur become quieter
JMJ 17
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Investigations• Chest X-ray• Electrocardiogram
• Echocardiogram• Cardiac magnetic resonance• Cardiac catheterization
JMJ 18
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Investigations –X-ray• Small heart with an enlarged L/ atrium
• Pulmonary venous hypertension
• Calcified mitral valve– on penetrated or lateral view
• Signs of pulmonary oedema or pulmonary hypertension
JMJ 19
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Investigations –ECG• Sinus rhythm in ECG shows a bifid P wave– Owing to delayed L/atrial activation
• Atrial fibrillation may be present
• ECG features of R/ventricular hypertrophy– Right axis deviation– Perhaps tall R wave in lead V1
JMJ 20
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Investigations –ECG
JMJ 21
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Investigations –ECG
JMJ 22
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Investigations –Echocardiogram• Transthoracic echocardiography– To determine L/ R/ atrial and ventricular
size– The sevirity of MS
• Transoesophageal Echocardiography (TOE)– To detect the presence of L/ atrial
thrombusJMJ 23
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Treatment• Need no treatment other than prompt therapy of
attacks of bronchitis
• Early symptoms like dyspnea - diuretics
• Onset of atrial fibrillation :digoxin, anticoagulants (to prevent atrial thrombus and systemic embolism)
• If pulmonary hypertension or symptoms of pulmonary congestion : surgical therapy
JMJ 24
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Treatment• Operative therapies– Trans-septal balloon valvotomy– Closed valvotomy– Open valvotomy–Mitral valve replacement
JMJ 25
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Treatment: Trans-septal balloon valvotomy
• Catheter introduced into R atriam via femoral vein• Under local anasthesia
• Inter atrial septum is punctured
• Catheter enter into left atrium then to mitral valve
• Balloon is inflated, briefly to split the valve commissures
JMJ 26
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Treatment: Trans-septal balloon valvotomy
JMJ 27
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Treatment: Trans-septal balloon valvotomy
• Complications– Regurgitation may result
• Contraindications– Heavy calcification–More than mild mitral regurgitation &
thrombus in the L/atrium
• TOE is done before this procedureJMJ 28
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Treatment: Closed valvotomy
• For the patients with – mobile, – non calcified and – non regurgitant mitral valves
• Fused cusps forced apart by a dilator (introduced through the apex of L/ ventricle)
• Cardiopulmonary bypass is not needed for this operation
JMJ 29
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Treatment: Open valvotomy
• Often preferred to closed valvotomy
• Cusps are carefully dissected apart under direct vision
• Cardiopulmonary bypass is requied
JMJ 30
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Treatment: Mitral valve replacement
• It is necessary if– Mitral regurgitation is present– Badly diseased or badly calcified stenotic
valve, – Moderate or severe mitral stenosis &
thrombus in L atrium despite anticoagulation
• Artificial valve >20 yrs• Anticoagulants are necessary
JMJ 31
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JMJ 32
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JMJ 33