An Evaluation and Pressure-Driven Design of Potable Water ...
Miniaturising Pressure-Driven-Flow...1 Miniaturising Pressure-Driven-Flow :Translating the...
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1 Miniaturising Pressure-Driven-Flow :Translating the laboratory set-up into a commercial instrument’ John Watson Business Development Manager, TTP Ventus.
Transcript of Miniaturising Pressure-Driven-Flow...1 Miniaturising Pressure-Driven-Flow :Translating the...
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Miniaturising Pressure-Driven-Flow
:Translating the laboratory set-up into a commercial instrument’
John Watson
Business Development Manager, TTP Ventus.
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Microfluidic pump optionsPeristaltic pump Syringe pump Pressure driven flow
Flow stability and precision Low Medium Excellent
Response time Low Low Excellent
Ultra smooth flow Low Medium Excellent
Direct handling of media (cross contamination)
Yes Yes No – reduces risk of cross contamination
Size, weight, noise Medium Poor Poor
Gas injection No No Yes
Injection of Nano-volume sample
Poor Good Medium*
Sample agitation Possible Not possible Possible
Sample temperature control
Possible Not Possible Possible
Dynamic flow range Good Poor Excellent
Fluid recirculation Yes No Yes**
* Limited only by flow sensor ** Valves needed
Pressure driven flowFlow stability and precision Excellent
Response time Excellent
Ultra smooth flow Excellent
Direct handling of media (cross contamination)
No – reduces risk of cross contamination
Size, weight, noise Poor
Gas injection Yes
Injection of Nano-volume sample
Medium*
Sample agitation Possible
Sample temperature control
Possible
Dynamic flow range Excellent
Fluid recirculation Yes**
*** Live poll active ***
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Why miniaturise Pressure-Driven-Flow ? Microfluidic trends
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Diagnostics
Point-of-Care (POC)MiniaturisationRapid-readout
Microfluidics holds the key!
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Attributes of Pressure-Driven-Flow
* Limited only by flow sensor ** Valves needed
Pressure driven flow
Flow stability and precision Excellent
Response time Excellent
Ultra smooth flow Excellent
Direct handling of media (cross contamination)
No – reduces cross contamination
Size, weight, noise Poor
Gas injection Yes
Injection of Nano-volume sample Medium*
Sample agitation Possible
Sample temperature control Possible
Dynamic flow range Excellent
Fluid recirculation Yes**
Pressure driven flow
Flow stability and precision Excellent
Response time Excellent
Ultra smooth flow Excellent
Direct handling of media (cross contamination)
No - reduces risk of cross contamination
Size, weight, noise Great (with Disc Pump)Gas injection Yes
Injection of Nano-volume sample Medium*
Sample agitation Possible
Sample temperature control Possible
Dynamic flow range Excellent
Fluid recirculation Yes**
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Disc Pump – For next generation Pressure-Driven-Flow systemsHigh precision flow control
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Disc Pump – For next generation Pressure-Driven-Flow systems
Response speed
Rapid response and precise flow-rate control, enabled by Disc Pump.
Flow rate stability
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Disc Pump – For next generation Pressure-Driven-Flow systems
Ultra-smooth flow
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Disc Pump – For next generation Pressure-Driven-Flow systems
Cost Silent operation
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Enabling innovation – Droplet microfluidics
Miniaturisation
Faster processing
Improved STATS
Lower cost
Control & precision
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Disc Pump – Organ-on-a-chip
Reinventing cellular research
TTP Cellpod
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• TTP Ventus evaluation kit and integration of SLF3x flow sensors
• Closed loop flow control
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TTP Ventus Disc Pump – New HP Series
• Pressure > 800 mbar
• Vacuum > 500 mbar
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• Pressure-Driven-Flow (PDF) offers many advantages with microfluidic systems
• The TTP Ventus Disc Pump enables miniaturisation and innovation in PDF systems with:Accurate & precise flow controlRapid response speedUltra smooth flow Silent operationCost effective solution
To summarise:
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TTP Ventus' pump will be the backbone of our point-of-care device. It is a powerful and compact design, and enables precise control of our microfluidics. The performance of the pump is only surpassed by the quality of the team behind it.
Victor Serdio, CTO, Mursla Ltd.
The TTP Ventus pump was used to develop innovative reagent delivery ideas for microfluidic point-of-care diagnostic devices. The pump’s precision and ultra-controllability offers bubble-free and pulse-free reagent delivery into microfluidic devices. Additionally, the size and customizability of these pumps makes them the best solution for fluid handling in portable infectious disease diagnostic devices. Prof. W Balachandran (Bala), Research Professor,
Brunel University London.
Thanks for listening!
