MILANO, AUGUST 25TH - 31ST 2019 CO-CHAIRS...Katharina Paschinger, Department für Chemie,...

MILANO, AUGUST 25TH - 31ST 2019

CO-CHAIRS:Prof. Sandro Sonnino

Prof. Alessandro Prinetti

PROGRAMME

SUNDAY 25TH AUGUST

14:00-15:00 15:00-16:00

16:00-17:00

17:00-18:00

18:00-18:30

19:00-22:00

Registration

OPENING CEREMONY

Sandro SonninoIGO President-elect, chair of Glyco25, Department of Medical Biotechnology and Translational Medicine, University of Milan

Elio FranziniRector of the University of Milan

Jin Won ChoIGO President, Department of Biomedical Science, Yonsei University, Seodaemun-gu, Seoul, Korea

Francesco NicotraIUPAC representative, University of Milano-Bicocca

Alessandro PrinettiCo-Chair and ISN representative, Department of Medical Biotechnology and Translational Medicine, University of Milan

CHOIR OF THE UNIVERSITY OF MILAN

IGO AWARD LAUREATEStuck on Sugars – How Carbohydrates Regulate Cell Adhesion, Recognition, and SignalingChairperson: K. KatoSpeaker: R. Cummings - Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA

IGO YOUNG SCIENTIST AWARD LAUREATEUnderstanding Microbial Glycosylation at the host-pathogen interface: How the glycoproteomes of pathogens shape infectionsChairperson: Y. ZickSpeaker: N. Scott - Department of Microbiology and Immunology at the University of Melbourne, Australia

Welcome Reception

AULA MAGNA

AUSPICES

MONDAY 26TH AUGUST

PROGRAMME

09:00-12:00

12:00-13:00

13:00-14:00

14:00-15:00

S1: MEMORIAL SESSION IN HONOR OF TAMIO YAMAKAWA: GLYCOBIOLOGY STARTED FROM GLYCOLIPIDS

HIS CAREER, WORK, AND WISHESKeynote speaker: Akemi Suzuki, Tohoku Medical and Pharmaceutical University, Sendai, Japan

TAMIO YAMAKAWA AWARDNaoyuki Taniguchi, Department of Glyco-Oncology and Medical Biochemistry, Osaka International Cancer Institute, Osaka, Japan

A DAY WITH YAMAKAWA SENSEI, CA 1990, AN EXAMPLE OF HIS ENGAGING PERSONALITYRoger Laine, Departments of Biological Sciences and Chemistry, Louisiana State University, Baton Rouge, LA, USA

TAMIO YAMAKAWA, A FRIENDLY AND GENEROUS PIONEER OF GLYCOBIOLOGYKonrad Sandhoff, LIMES, Rheinische Friedrich-Wilhelms-Universitaet Bonn

GANGLIOSIDE STRUCTURESSandro Sonnino, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy

GM3, HEMATOSIDE, IS A NEW TARGETJin Inokuchi, Institute of Molecular Biomembrane and Glycobiology, Division of Glycopathology, Tohoku Medical and Pharmaceutical University, Sendai, Japan

MOLECULAR ORGANISATION OF THE (GLYCO)SPHINGOLIPID SYNTHETIC MACHINERYGiovanni D’Angelo, Institute of Bioengineering, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland

Short talk from abStractS

Plenary Lecture 1: GANGLIOSIDE FUNCTIONS IN THE HUMAN BRAIN AND PERIPHERAL NERVOUS SYSTEMChairperson: J.L. DaniottiSpeaker: Ronald L. Schnaar, Departments of Pharmacology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Lunch and poster view

Poster session

AULA MAGNA

MONDAY 26TH AUGUST

PROGRAMME

15:00-19:00 S4: FATHOMING GLYCAN RECOGNITION IN HEALTH AND DISEASE

THE QUEST FOR WAYS TO UNRAVEL GLYCAN RECOGNITION SYSTEMSKeynote speaker: Ten Feizi, The Glycosciences Laboratory, Imperial College London, London, UK

THE ROLE OF SIALYLATION IN THE LIFE CYCLE OF AFRICAN TRYPANOSOMESSoerge Kelm, Department of Biology and Chemistry, University of Bremen, Bremen, Germany

UNDERSTANDING AND EXPLOITING IMMUNE RECOGNITION OF CARBOHYDRATESJeff Gildersleeve, Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA

GLYCAN MICROARRAYS SHEDDING LIGHT ON GLYCAN RECOGNITION BY VIRUSESYan Liu, Institute for Reproductive and Developmental Biology, Imperial College London, London, UK

PROBING GLYCAN-GLYCAN BINDING PROTEIN INTERACTIONS USING A CHEMOENZYMATIC APPROACHPeng Wu, Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA

DEVELOPMENT OF GENETICALLY ENCODED, LIQUID GLYCAN ARRAY TECHNOLOGY TO PROBE GLYCAN RECOGNITION EX VIVO AND IN VIVORatmir Derda, Department of Chemistry, University of Alberta, Edmonton, Canada

USING 1K SYNTHETIC GLYCOMICS LIBRARY TO SEARCH FOR PROTEIN BINDINGGeorge Peng Wang, Department of Chemistry, Georgia State University, Atlanta, GA, USA


AULA MAGNA

MONDAY 26TH AUGUST

PROGRAMME

09:00-12:00

13:00-14:00

14:00-15:00

15:00-19:00

S2: GLYCOSYLATION IN INVERTEBRATES

PROTEIN N-GLYCOSYLATION IS SEX-RELATED IN NILAPARVATA LUGENSKeynote speaker: Els van Damme, Department of Biotechnology, Ghent University, Ghent, Belgium

A DROSOPHILA MODEL FOR INVESTIGATING THE NEUROLOGICAL DEFECTS ASSOCIATED WITH CONGENITAL DISORDER OF GLYCOSYLATION TYPE IIEMariagrazia Giansanti, Dipartimento di Biologia e Biotecnologie, Università Sapienza di Roma, Roma, Italy

FUNCTIONAL ANALYSIS OF MUCIN-TYPE O-GLYCANS USING DROSOPHILA MELANOGASTERShoko Nishihara, Department of Bioinformatics, Graduate School of Engineering, Soka University, Hachioji, Japan

RESOLVING UNUSUAL N-GLYCANS IN LOWER EUKARYOTESKatharina Paschinger, Department für Chemie, Universität für Bodenkultur, Vienna, Austria



Poster session

S5: GLYCOBIOLOGY AND NEURODEGENERATIONS

Keynote speaker: Robert Ledeen, Rutgers New Jersey Medical School, Newark, NJ, USA

Elena Chiricozzi, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy

Simonetta Sipione, University of Alberta, Edmonton, AB, Canada

Michael P. McDonald, Depts. of Neurology and Anatomy & Neurobiology, Director of Alzheimer Research, Memphis, TN, USA

IMPACTS OF GLYCOSHINGOLIPIDS AND THEIR AUTOANTIBODIES ON NEUROLOGICAL DISORDERSTatsuro Mutoh, Department of Neurology & Neuroscience, Fujita Health University School of Medicine, Japan


ROOM 2

09:00-12:00

13:00-14:00

14:00-15:00

15:00-19:00

S3: SIALYLATION AND SIALIDASES IN SIGNALING, IMMUNITY AND METABOLISM

EMERGING ROLES OF MAMMALIAN NEURAMINIDASES IN CNS DEVELOPMENT AND METABOLIC REGULATIONKeynote speaker: Alexey V. Pshezhetsky, Sainte-Justine Hospital Research Center, University of Montreal, McGill University, Department of Anatomy and Cell Biology, Montreal, Canada

INHIBITORS OF THE HUMAN NEURAMINIDASE ENZYMES AS PROBES IN GLYCOBIOLOGYChristopher W. Cairo, Alberta Glycomics Centre and Department of Chemistry, University of Alberta, Edmonton, Canada

SPREADING THE NEUS: THE ROLE OF SIALIDASES IN THE PULMONARY INNATE IMMUNE RESPONSEAlan Cross, Institute for Global Health, University of Maryland School of Medicine, Baltimore, MD, USA

ACUTE STRESS-INDUCED CHANGE OF POLYSIALIC ACID EXPRESSION MEDIATED BY SIALIDASE IN MOUSE BRAINChihiro Sato, Bioscience and Biotechnology Center, Nagoya University, Chikusa, Nagoya, Japan



Poster session

S6: BACTERIA AND GLYCOCONJUGATES

Keynote Speaker: Sho Yamasaki, Immunology Frontier Research Center (IFReC), Osaka University, Suita, Japan

Hitoshi Nakayama, Juntendo University Faculty of Health Care and Nursing, Tokyo, Japan

Jérôme Nigou, Département “Tuberculose & Biologie des Infections”, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, Toulouse, France

Makoto Ito, Graduate School of Bioresource and Bioenvironmental Science,Kyusyu University

Yoshio Hirabayashi, RIKEN Cluster for Pioneering Research, Japan

Jukka Finne, Division of Biochemistry and Biotechnology, Department of Biosciences, University of Helsinki, Helsinki, Finland


ROOM 3

MONDAY 26TH AUGUST

PROGRAMME

TUESDAY 27TH AUGUST

PROGRAMME

09:00-12:00

12:00-13:00

13:00-14:00

14:00-15:00

S7: UNRAVELING THE MECHANISMS OF ORGANIZATION AND PHYSIOLOGICAL FUNCTIONS OF GLYCOLIPID-ENRICHED MEMBRANE DOMAINS

OVER VIEW: ORGANIZATION AND PHYSIOLOGICAL FUNCTIONS OF GLYCOLIPID-ENRICHED MEMBRANE DOMAINSKeynote speaker: Kazuhisa Iwabuchi, Graduate school of Medicine, Juntendo University, Chiba, Japan

REGULATION MECHANISMS OF EGF RECEPTOR FUNCTION BY GANGLIOSIDES AS REVEALED BY SINGLE-MOLECULE IMAGINGKeynote speaker: Kenichi G.N. Suzuki, Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto, Japan

GLYCOSPHINGOLIPID-LIPID INTERACTIONS AND DOMAIN FORMATION IN MODEL BILAYER MEMBRANESShinya Hanashima, Department of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan

ANALYSIS OF ELECTROSTATIC INTERACTION BETWEEN GANGLIOSIDE GM3 AND INSULIN RECEPTORKazuya Kabayama, Department of Chemistry, Graduate School of Science, Osaka University, Osaka, Japan

Toshihide Kobayashi, Directeur de recherche INSERM, Faculté de Pharmacie, Université de Strasbourg, Strasbourg, France

INDICATION OF THE INVOLVEMENT OF A GOLGI SPHINGOMYELIN-ENRICHED DOMAIN IN THE INNATE-IMMUNITY SIGNALLINGTomohiko Taguchi, Laboratory of Organelle Pathophysiology, Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Japan

Liana C. Silva, iMed.ULisboa, Research Institute for Medicines, Faculdade de Farmácia, Universidade de Lisboa, Portugal


Plenary Lecture 2: NOVEL WAYS TO REGULATE HEPARAN SULFATE ASSEMBLYChairperson: P. BonaySpeaker: Jeffrey D. Esko, Department of Cellular and Molecular Medicine, Glycobiology Research & Training Center, University of California, San Diego, School of Medicine, La Jolla, CA, USA


Poster session

AULA MAGNA

15:00-19:00 S9: GLYCOSAMINOGLYCANS: A SEQUENCE FOR MULTIPLE FUNCTIONS OR MULTIPLE SEQUENCES FOR A FUNCTION?

REGULATION OF HEPARAN SULFATE BIOSYNTHESIS - ENOUGH IS ENOUGHKeynote speaker: Ulf Lindahl, Uppsala University, The Biomedical Center, Uppsala, Sweden

DISTINCT HEPARAN SULFATES MODULATE WNT SIGNALING IN A CONTEXT-DEPENDENT MANNERHannes Bülow, Albert Einstein College of Medicine, New York, NY, USA

ANTITHROMBIN-BINDING HEPARIN SEQUENCES: ALTERNATIVE STRUCTURES FOR THE SAME FUNCTIONMarco Guerrini, Istituto di Ricerche Chimiche e Biochimiche “G. Ronzoni”, Milan, Italy

Lena Kjellén, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

WHAT DO CHEMOKINES SEE ON THE CELL SURFACE HEPARAN SULFATE?Hugues Lortat-Jacob, Université Grenoble-Alpes, Grenoble, France

HARNESS HEPARAN SULFATE BIOSYNTHETIC PATHWAY TO PREPARE HOMOGENEOUS OLIGOSACCHARIDESJian Liu, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA


AULA MAGNA

TUESDAY 27TH AUGUST

PROGRAMME

TUESDAY 27TH AUGUST

PROGRAMME

09:00-12:00

13:00-14:00

14:00-15:00

15:00-19:00

S8: NOVEL THERAPEUTIC APPLICATIONS FROM GLYCOSCIENCES FOR UNMET MEDICAL NEEDS

TWO GLYCOMIMETIC DRUGS, UPROLESELAN AND GMI-1359, IN CLINICAL TRIALS FOR ACUTE MYELOGENOUS LEUKEMIA AND BREAST CANCERKeynote speaker: John L. Magnani, Glycomimetics, Rockville, MD, USA

GALECTINS AS DRUG TARGETS: DESIGN OF INHIBITORS, THEIR BIOLOGICAL EFFECTS, AND POSSIBLE USE IN FIBROTIC DISEASE, CANCER AND OTHERSHakon Leffler, Lund University, Lund, Sweden

DESIGNER SULFONATED SIALIC ACIDS ARE POTENT INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASEMark von Itzstein, Institute for Glycomics , Griffith University, Gold Coast Campus, Australia

INHIBITING GLYCOIMMUNE CHECKPOINTS WITH NOVEL BISPECIFIC-LIKE ENZYME THERAPEUTICS TO TREAT CANCERLi Peng, SVP of Discovery and Early Product Development, Palleon Pharmaceuticals, Waltham, MA, USA

BACTERIAL POLYSACCHARIDES IN CANCER THERAPYRoger Laine, Departments of Biological Sciences and Chemistry, Louisiana State University, Baton Rouge, LA, USA



Poster session

S10: CELL SURFACE HYDROLASES AND TRANSFERASES

MEMBRANE LIPIDS AND THE ACTIVITY OF SPHINGOLIPID-CLEAVING HYDROLASESKeynote speaker: Konrad Sandhoff, LIMES Institute, Membrane Biology & Lipid Biochemistry Unit, Universität Bonn, Bonn, Germany

PLASMA MEMBRANE β-GLUCOCEREBROSIDASES IN NEURONAL DIFFERENTIATION AND SENESCENCEMassimo Aureli, Department of Medical Biotechnology and Translational Medicine, University of Milano, Italy

Jose Luis Daniotti, Research Centre in Biologocal Chemisty of Cordoba (CIQUIBIC), CONICET-UNC, Cordoba, Argentina

Taeko Miyagi, Miyagi Cancer Center Research Institute, Sendai, Japan


ROOM 2

15:00-19:00 S11: TRANSLATIONAL RESEARCH IN GLYCOSCIENCE(jointly organized with the asian Community for glyCobiology and glyCoteChnology)

DEVELOPMENT OF DIAGNOSTICS AFTER DISCOVERY OF GLYCOBIOMARKERSKeynote speaker: Hisashi Narimatsu, RCMG Inc. and AIST, Japan

GLYCOPROTEOMIC IDENTIFICATION OF ENTEROVIRUS A71 RECEPTORSChuan-Fa Chang, Dep. of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University,Tainan, Taiwan

DIAGNOSTIC SIGNIFICANCE OF SERUM IGG GALACTOSYLATION IN CANCERSShifang Ren, NHC Key Laboratory of Glycoconjugates Research, Dep. of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China

THE PHAGE-ASSISTED PREPARATION OF GLYCOCONJUGATE VACCINES AGAINST NOSOCOMIAL BACTERIAL INFECTIONShih-Hsiung Wu, Institute of Biological Chemistry, Academia Sinica, Taiwan


ROOM 3

TUESDAY 27TH AUGUST

PROGRAMME

WEDNESDAY 28TH AUGUST

PROGRAMME

09:00-12:00

12:00-13:00

S12: GLYCOCONJUGATE BIOPHYSICS: FACTS, FIGURES AND METHODS

Chair: Laura Cantù, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy

Thomas Zemb, Institut de Chimie Separative de Marcoule (ISCM), CEA Marcoule, Bagnols-sur-Cèze, France

Marcello Sega, Forschungszentrum Jülich GmbH,Helmholtz-Institut Erlangen-Nürnberg, Nürnberg, Deutschland

Elena Del Favero, Department of Medical Biotechnology and Translational Medicine, University of Milan, Italy


Plenary Lecture 3: CHEMISTRY AND BIOLOGY OF POLYSIALIC ACIDChairperson: P. DelannoySpeaker: Rita Gerardy-Schahn, Institute of Clinical Biochemistry, Hannover Medical School, Germany

AULA MAGNA

WEDNESDAY 28TH AUGUST

PROGRAMME

09:00-12:00

ROOM 2

S13: GLYCATION – PROTEIN-BASED GLYCOCONJUGATES ON LYSINE, ARGININE AND N-TERMINUS. RELATION TO AGING, DIABETES AND OTHER HEALTH IMPAIRMENTS

PHYSIOLOGICAL GLYCATION BY GLUCOSE AND REACTIVE DICARBONYL METABOLITE, METHYLGLYOXAL – TARGETS, HOTSPOTS AND ENGAGEMENT WITH THE UNFOLDED PROTEIN RESPONSEKeynote speaker: Paul J. Thornalley, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha, Qatar

TISSUE, SERUM AND URINE GLYCATION MARKERS AS LONG-TERM PROGNOSTICATORS OF COMPLICATIONS IN TYPE 1 DIABETESVincent Monnier, Case Western Reserve University, Cleveland, Ohio, USA

APPLICATION OF GLYCATED PROTEINS AND RELATED ANALYTES IN CLINICAL DIAGNOSIS. BEYOND GLYCATED HEMOGLOBIN AND DIABETESNaila Rabbani, University of Warwick, Coventry, UK


09:00-12:00 S14: GOLGI DYNAMICS IN HEALTH AND DISEASE

Keynote Speaker: Paul A. Gleeson, Department of Biochemistry and Molecular Biology, Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Australia

Vladimir Lupashin, Department of Physiology and Biophysics, College of Medicine. University of Arkansas for Medical Sciences, Little Rock, AR, USA

STEREO-SPECIFIC SUBSTRATES (CERAMIDE GLYCOMES) AND GENOMIC EXPRESSION OF SPECIFIC GLYCOSYLTRANSFERASES GUIDE BIOSYNTHETIC PATHWAYS OF SPHINGOGLYCOLIPIDSSubhash Basu, Founding President, Cancer Drug Delivery Research Foundation, University of Notre Dame, Notre Dame; IN, USA


ROOM 3

THURSDAY 29TH AUGUST

PROGRAMME

09:00-12:00

12:00-13:00

13:00-14:00

14:00-15:00

S15: LECTINS AND GALECTINS

THE REPERTOIRE OF BETA-PRISM FOLD LECTINS; SPECIFICITIES AND THERAPEUTIC POTENTIALKeynote speaker: Avadhesha Surolia, Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India

ANTIVIRAL LECTINS FROM NATURAL PRODUCT EXTRACTS: FROM DISCOVERY TO THE CLINICBarry R. O’Keefe, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, MD, USA

LECTIN-DRIVEN AND GLYCOSPHINGOLIPID-DEPENDENT CONSTRUCTION OF ENDOCYTIC PITS FOR POLARIZED PROTEIN DISTRIBUTION BY TRAFFICKING VIA THE RETROGRADE ROUTELudger Johannes, Institut Curie, PSL Research University, U1143 INSERM — UMR3666 CNRS, Paris, France GALECTIN-3 INTERACTION WITH NEUTROPHILS – GRANULES, GAL-3C AND GLYCANSAnna Karlsson-Bengtsson, Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Göteborg, Sweden

CARBOHYDRATE-SPECIFIC COMPUTATIONAL METHODS FOR THE REFINEMENT, VALIDATION AND REPRESENTATION OF STRUCTURES OF GLYCAN-LECTIN COMPLEXESJon Agirre, Department of Chemistry, University of York, York, UK


Plenary Lecture 4: BIOLOGICAL FUNCTIONS OF SIGLECS EXPRESSED ON MYELOID CELLSChairperson: I. BrockausenSpeaker: Paul Crocker, Division of Cell Signalling and Immunology, School of Life Sciences, University of Dundee, Dundee, Scotland UK


Poster session

AULA MAGNA


PROGRAMME

15:00-19:00 S17: GLYCOIMMUNOLOGY AND INFLAMMATION

HOMEOSTATIC AND PATHOGENIC ROLES OF GM3 GANGLIOSIDE MOLECULAR SPECIES IN TLR4 SIGNALING IN METABOLIC DISORDERSKeynote speaker: Jin-ichi Inokuchi, Tohoku Medical and Pharmaceutical University, Sendai, Japan

IMMUNE RECOGNITION OF GLYCANS IN ADAPTIVE AND INNATE RESPONSESRichard D. Cummings, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

Brian A. Cobb, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, USA

SYNTHESIS AND BIOFUNCTIONAL STUDIES OF IMMUNOMODULATING GLYCOCONJUGATESKoichi Fukase, Department of Chemistry, Graduate School of Science, Osaka University, Japan

James C. Paulson, Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA


AULA MAGNA


PROGRAMME

09:00-12:00

13:00-14:00

14:00-15:00

15:00-19:00

S16: GLYCOBIOLOGY OF MICROBIOTA

GUT MICROBIOTA LIPOPOLYSACCHARIDES: REVERTING THE CONCEPT FROM BAD TO GOODKeynote speaker: Antonio Molinaro, University of Naples Federico II, Naples, Italy

SIALIC ACID METABOLISM BY GUT BACTERIAKeynote speaker: Nathalie Juge, Quadram Bioscience Institute, Norwich, UK

SYNTHESIS AND IMMUNOMODULATING FUNCTIONS OF SYMBIOTIC BACTERIAL LIPOPOLYSACCHARIDE PARTIAL STRUCTURESAtsushi Shimoyama, Department of Chemistry, School of Science, Osaka University

MOLECULAR BASIS OF BROAD SPECTRUM N-GLYCAN SPECIFICITY AND PROCESSING OF IGG ANTIBODIES BY ENDOGLYCOSIDASE S2Marcelo E. Guerin, Ikerbasque Research Professor, Head of the Structural Glycobiology Group, Structural Biology Unit - CIC bioGUNE, Technological Park of Bizkaia, Derio, Vizcaya, Spain



Poster session

S18: GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED PROTEINS

REGULATION OF GLYCOSYLPHOSPHATIDYLINOSITOL BIOSYNTHESISKeynote speaker: Taroh Kinoshita, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

PROCESSING OF GPI-ANCHORS IN THE ENDOPLASMIC RETICULUMMorihisa Fujita, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu, China

Satyajit Mayor, National Centre for Biological Sciences, Bangalore, India

SORTING DETERMINANTS FOR DIFFERENTIAL ER EXIT OF GPI-ANCHORED PROTEINSManuel Muñiz, Department of Cell Biology, University of Seville, Seville, Spain


ROOM 2

FRIDAY 30TH AUGUST

PROGRAMME

09:00-12:00

12:00-13:00

13:00-14:00

14:00-15:00

S19: ABERRANT GLYCOSYLATION IN CANCER

Keynote speaker: Naoyuki Taniguchi, Osaka International Cancer Institute, Osaka, Japan

ESTABLISHMENT OF A NOVEL GLYCAN ANTIBODY FOR FUCOSYLATED HAPTOGLOBIN AND ITS POSSIBLE IMPLICATION OF CLINICAL INVESTIGATIONEiji Miyoshi, Osaka University Medical School, Japan

Yuanyuan Ruan, Department of Biochemistry and Molecular Biology, Fudan University, Shanghai, China

Claudine Kieda, Centre for Molecular Biophysics, CNRS, 45071, Orleans, France


Plenary Lecture 5: A GENETIC DISSECTION APPROACH TO FUNCTIONAL GLYCOMICSChairperson: A. DellSpeaker: Henrik Clausen, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark


Poster session

AULA MAGNA

FRIDAY 30TH AUGUST

PROGRAMME

AULA MAGNA

15:00-19:00 S22: GLYCO(PROTEO)MICS

SIGHTING OF UNUSUAL N-GLYCANS IN VIRUSES AND HUMANSDomenico Garozzo, CNR Istituto per i Polimeri Compositi e Biomateriali IPCB, Catania, Italy

Catherine E. Costello, Center for Biomedical Mass Spectrometry, Boston University School of Medicine, Boston, MA, USA

SULFOGLYCOMICSKay-hooi Khoo, Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan

Daniel Kolarich, Institute for Glycomics, Griffith University, Brisbane, QLD, Australia

GLYCAN BIOMARKERS AS EARLY PREDICTORS OF CARDIOVASCULAR DISEASES AND DIABETESGordan Lauc, University of Zagreb Faculty of Pharmacy and Biochemistry, Zagreb, Croatia

MASS SPECTROMETRIC GLYCOMICS OF CANCER AND AUTOIMMUNE DISEASESManfred Wuhrer, Center for Proteomics and Metabolomics, Leiden University Medical Center, Netherlands

Nicki Packer, Department of Molecular Sciences, Macquarie University, North Ryde, Sydney, NSW, Australia


FRIDAY 30TH AUGUST

PROGRAMME

09:00-12:00

13:00-14:00

14:00-15:00

15:00-19:00

S20: CONGENITAL DISORDERS OF GLYCOSYLATION

CONGENITAL DISORDERS OF GLYCOSYLATION (CDG): AN OVERVIEWKeynote speaker: Jaak Jaeken, University Hospital Gasthuisberg, Leuven, Belgium

François Foulquier, Unité de Glycobiologie Structurale et Fonctionelle (UGSF), University of Lille, Lille, France

Dirk Lefeber, Radboud University Medical Center, Nijmegen, The Netherlands

Gert Matthijs, Center for Human Genetics, KU Leuven, Leuven, Belgium



Poster session

S23: O-GLCNAC AND THE REGULATION OF CELL PHYSIOLOGY

CHEMICAL TOOLS FOR STUDYING O-GLCNACKeynote speaker: David J. Vocadlo, Departments of Chemistry and Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, Canada

Jin Won Cho, Department of Biomedical Science, Yonsei University, Seoul, Korea

THE MANY ROLES OF O-GLCNAC IN PROMOTING THE STRESS RESPONSENatasha Zachara, Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, USA

REGULATION OF CELL HOMEOSTASIS BY O-GLCNACYLATIONTony Lefebvre, Structural and Functional Glycobiology Unit, CNRS, Lille 1 University, Villeneuve d’Ascq, France

WHEN O-GLCNAC MEETS THE CLOCKPhilippe-Claude Lefebvre, University of Lille, Inserm, Centre Hospitalier Universitaire de Lille, Institut Pasteur de Lille, Lille, France


ROOM 2

09:00-12:00 S21: PLANT GLYCOBIOLOGY

FILLING THE GAPS TO SOLVE THE EXTENSIN PLANT GLYCOPROTEIN PUZZLEKeynote speaker: Jose M. Estevez, Head of Laboratory -Molecular Basis for Plant Development-Leloir Institute, Buenos Aires, Argentina

PLANT N-GLYCOSYLATION AND ENZYMES INVOLVEDRichard Strasser, Boku Viena, Austria

STRESS INDUCIBLE PLANT LECTINSMalgorzata Dubiel, Ghent University, Belgium

SYNTHETIC PLANT GLYCANS AS TOOLS FOR CELL WALL BIOLOGYFabian Pfrengle, Max Planck Institute of Colloids and Interfaces, Potsdam Germany


ROOM 3

FRIDAY 30TH AUGUST

PROGRAMME

SATURDAY 31ST AUGUST

PROGRAMME

09:00-12:00

12:00-13:00

13:00-14:00

S24: ISN SYMPOSIUM-MEMBRANE CONTACT SITES IN NEURODEGENERATIVE DISORDERS

INVOLVEMENT OF MEMBRANE CONTACT SITES IN THE NEUROPATHOGENESIS OF A GLYCOSPHINGOLIPID STORAGE DISEASEKeynote speaker: Alessandra d’Azzo, Department of Genetics, St. Jude Children’s Research Hospital, Memphis, TN, USA

ORGANELLE CONTACT SITES: WHAT ARE THEY, WHAT ARE THEY GOOD FOR AND HOW CAN THEY BE BADBenoît Kornmann, Department of Biochemistry and ST-Hugh’s College, University of Oxford, Oxford UK

VPS13 PROTEINS: LIPID TRANSPORTER LOCALIZED AT MEMBRANE CONTACT SITES AND IMPLICATED IN NEURODEGENERATIONMarianna Leonzino, Department of Neuroscience, Yale University and Howard Hughes Medical Institute, New Haven, CT, USA

MECHANISTIC CONNECTIONS BETWEEN ER STRESS AND MITOCHONDRIA-ASSOCIATED MEMBRANESThomas Simmen, Department of Cell Biology, University of Alberta, Edmonton, Canada


Plenary Lecture 6: IUBMB JUBILEE LECTURE: “CYTOSOLIC GALECTINS AS SENSORS FOR ENDO-LYSOSOMAL DAMAGE”Chairperson: Franco Bonomi, University of Milan, IUBMB representativeSpeaker: Fu-Tong Liu, Academia Sinica, Taipei, Taiwan

CLOSING CEREMONY

Poster Awards

Presentation of the Glyco26, 2021 Taipei, Taiwan,

IGO President, Jin Won Cho

Glyco25 chairpersons, Sandro Sonnino and Alessandro Prinetti

AULA MAGNA

SATURDAY 31ST AUGUST

PROGRAMME

09:00-12:00

ROOM 2

S25: GLYCOCONJUGATE VACCINES: PRESENT AND FUTURE

GLYCOCONJUGATE VACCINES: PRESENT AND FUTUREKeynote speaker: Roberto Adamo, GSK Vaccines srl, Siena, Italy

Johannes Huebner, Dr. v. Hauner Children’s Hospital, LMU Munich, University of Munich (LMU), Germany

Laurence Mulard, Institut Pasteur, Paris, France

Claney L. Pereira, Vaxxilon Deutschland GmbH, Berlin, Germany

Jon Cuccui, Dep. of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, UK

Francesca Micoli, GSK Vaccines srl, Siena, Italy

GOLD NANOPARTICLES TO INTERROGATE IMMUNOLOGICAL PROPERTIES OF CARBOHYDRATES IN THE CONTEXT OF CONJUGATE-VACCINESFabrizio Chiodo, Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University, The Netherland


09:00-12:00 S26: GLYCOSYLATION IN CANCER DIAGNOSIS AND THERAPY

CELLULAR GLYCOSYLATION: BIOSYNTHESIS AND FUNCTIONAL IMPLICATIONS IN CANCERKeynote Speaker: Celso Albuquerque Reis,Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal

ST6GAL-I SIALYLTRANSFERASE HAS TUMOR-PROMOTING ACTIVITY THROUGH ITS ROLE IN IMPARTING A CANCER STEM CELL PHENOTYPESusan L. Bellis, University of Alabama at Birmingham, Birmingham, AL, USA

Pauline M. Rudd, University College Dublin, Belfield, Dublin, Ireland

TUMOR-ASSOCIATED GLYCAN STRUCTURES:FRIEND OR FOE IN IMMUNITY TO CANCER?Sandra J. van Vliet, Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Amsterdam, The Netherlands


ROOM 3

CONFERENCE VENUE

Via Festa del Perdono 7Milano

www.glyco25.org

ORGANIZING SECRETARIATMZ Congressi srlVia Farini 81, 20129 MilanoTel +39 02 [email protected]

MILANO, AUGUST 25TH - 31ST 2019 CO-CHAIRS...Katharina Paschinger, Department für Chemie,...

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Transcript of MILANO, AUGUST 25TH - 31ST 2019 CO-CHAIRS...Katharina Paschinger, Department für Chemie,...