MigraineMigraine

Definition Definition

Migraine is more of neurological syndrome Migraine is more of neurological syndrome characterized by altered bodily perceptions, characterized by altered bodily perceptions, headache and nausea, that is more common in headache and nausea, that is more common in females than males.females than males.

Few define it as a form of vascular headache Few define it as a form of vascular headache caused by a combination of vasodilatation caused by a combination of vasodilatation (enlargement of blood vessels) and the release (enlargement of blood vessels) and the release of chemicals from nerve fibers that coil around of chemicals from nerve fibers that coil around the blood vessels. the blood vessels.

Pathophysiology Pathophysiology

Migraine has long been regarded as a vascular Migraine has long been regarded as a vascular disorder because of the throbbing nature of the disorder because of the throbbing nature of the pain. However, vascular changes do not provide pain. However, vascular changes do not provide sufficient explanation of the pathophysiology of sufficient explanation of the pathophysiology of migraine. Up to one-third of patients do not migraine. Up to one-third of patients do not have throbbing pain. Modern imaging has have throbbing pain. Modern imaging has demonstrated that vascular changes are not demonstrated that vascular changes are not linked to pain and diameter changes are not linked to pain and diameter changes are not linked with treatmentlinked with treatment

Twin Studies: MZ>DZTwin Studies: MZ>DZ

Vulnerability: Genetic BasisVulnerability: Genetic Basis

ComparisonComparison

PsoraPsora Time Time

Morning headacheMorning headache LocationLocation

Frontal, Temporal, Tempo-parietalFrontal, Temporal, Tempo-parietal CharacterCharacter Headache is sharp, severe, paroxysmalHeadache is sharp, severe, paroxysmal SymptomsSymptoms

Headache with bilious attack of nausea Headache with bilious attack of nausea and vomiting, red face and throbbingand vomiting, red face and throbbing

ModalityModality Aggravation Aggravation

In morningIn morning AmeliorationAmelioration

By rest, sleep, hot applicationBy rest, sleep, hot application

SYPHILISSYPHILIS TimeTime

NightNight LocationLocation

Usually Basilar, Linear, or one Usually Basilar, Linear, or one sidedsided

Character Character Dull, Heavy, Lancinating, Constant Dull, Heavy, Lancinating, Constant

, Persistent, Persistent ModalityModality

AggravationAggravation At Night , Lying down, At Night , Lying down,

Warmth, Rest, While Warmth, Rest, While attempting to sleepattempting to sleep

AmeliorationAmelioration In morning, By ColdIn morning, By Cold

ComparisonComparison

SYCOSISSYCOSIS TimeTime

Night or after midnightNight or after midnight LocationLocation

Frontal or on VertexFrontal or on Vertex CharacterCharacter

Headache of Sycotic childrenHeadache of Sycotic children Produces Feverishness, Produces Feverishness,

Restlessness, Crying, Freting, and Restlessness, Crying, Freting, and WorryingWorrying

ConcomitantConcomitant Coldness of body, sadness and Coldness of body, sadness and

prostrationprostration ModalityModality

AggravationAggravation By lying down, At Night, By lying down, At Night,

Riding, By exertion either Riding, By exertion either physical or mentalphysical or mental

AmeliorationAmelioration By motionBy motion

TUBERCULARTUBERCULAR TimeTime

Headache occurring WeeklyHeadache occurring Weekly CharacterCharacter

Headache is very severe and Headache is very severe and persistentpersistent

ConcomitantConcomitant Coldness of hands and feet, Coldness of hands and feet,

sadness and general despondencysadness and general despondency SymptomsSymptoms

Patient has weak feeling about the Patient has weak feeling about the head, can not hold it up, head, can not hold it up, producing unconsciousness, rolling producing unconsciousness, rolling or boring of head into the pillow, or boring of head into the pillow, feverishness, and restlessness, feverishness, and restlessness, rush of blood to head or face, with rush of blood to head or face, with roaring in earsroaring in ears

Headache of childrenHeadache of children They strike, knock or pound their They strike, knock or pound their

heads with their hands or against heads with their hands or against some object and great hunger some object and great hunger before headache and headache before headache and headache from repelled eruption or from repelled eruption or suppression of any skin eruptionsuppression of any skin eruption

ModalityModality AggravationAggravation

By riding in carriage, By riding in carriage, preparing for examination, preparing for examination, meeting with strangers and meeting with strangers and enertaining themenertaining them

AmeliorationAmelioration By rest, quiet, sleep, eating, By rest, quiet, sleep, eating,

and nose bleedingand nose bleeding By cold applicationBy cold application