Microbiome - Competitive Landscape, Technology and Pipeline Analysis

2017

3D STEPS

Microbiome

Microbiome refers to collection of microbes and their interaction with the human body.

They tend play an important role in human physiology and disease.

The market of microbiome therapies is progressing rapidly. Various companies are getting on

the action, aiming to target microbes to treat various types of diseases.

Human body possess number of different species of bacteria and fungi which

help in digesting food, preventing infections, perform numerous life-supporting tasks. Microbes

can also be harmful to their human hosts.

What is Microbiome?

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There are total 70+ drugs in pipeline. 30+ products are in Pre-

clinical, 15+ products are in Discovery stage of development and a few

products are in Unknown stage of

development.

Key Market Driversfor microbiome are

Advanced Technology as well

Increased Collaborations &

Acquisitions

Key Market Barriers are Optimization of dosing & mitigation of Toxicity as well Scalability and

cost to ensure accessibility

& affordability

Most Prominent Indications includes Clostridium Difficile

Infection, Inflammatory Bowel Disease,

Prediabetes, Type II Diabetes Mellitus

Some Key Findings from the report

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CHART

“Synlogic is developing 5+

drugs that address disease

by targeting gut microbiome

using their synthetic biotic

approach. They collaborated

to create innovative

synthetic biotic for the

treatment of major diseases”

Some Key Findings from the report

50% Apogenix

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0

5

10

15

20

25

30

NU

MB

ER O

F P

RO

DU

CTS

THERAPY AREA

Number of Products (N) with Therapy AreaThe market of microbiome therapies is progressing rapidly. Various companies

are getting onthe action, aiming to target microbes to

treat various types of diseases. The therapeutics are used across many therapy areas. Major therapy areas

focused by pipeline drugs for microbiome are Gastrointestinal, Metabolic Disorders,

Infectious Disease, Dermatology.

CHART

Some Key Findings from the report Conti.

50% Apogenix

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0

2

4

6

8

Nu

mb

er

of

Pro

du

cts

Technology

The technology used by each company is given below. The maximum product isbeing developed by using MiNE (Microbiome isolates and Novel Extracts)platform of Quorum Innovations followed by Assembly Biosciences. EnteromeBioscience, Microbiome therapeutics and Immuron is developing two productsby using their own technology.

Role of Microbiota in Health and Disease

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DIAGRAM

Role in GastroIntestinal

Disease

Role in Metabolic Disorders

Role in Inflammatory

Bowel Diseases

Role in Cancers

Role in Diabetes

Role in Cardiovascular

diseases

Microbiota

Overview of the global Microbiome pipeline scenario, products and associated companies information

Coverage of global Microbiome under development as well as Competitive landscape of products for key players and related indications

Pipeline analysis across different phases, emerging trends and comparative analysis of pipeline products with detailed clinical profiles, MOA, route of administration and molecule type etc.

Coverage of licensors, collaborators and Development partners, deal terms and deal values estimation

Highlights of licensing & collaboration opportunities and funding details along with Microbiome technologies and innovative companies

Microbiome: Report Highlights

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