FINAL

MF-8 Eighth Microfluidics Consortium

MF-8.5

(Closed Meeting – Members Only)

October 11th Cambridge UK

(Open Meeting – Day Delegates + Members),

October 12th Cambridge UK

Agenda

Delegate List

Speaker Profiles

Table-top Demonstrations

Hotel and Travel Recommendations

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The Eighth Microfluidics Consortium brings together current and future stakeholders from across a wide range of backgrounds with a shared interest in facilitating the growth of the industry through better understanding of the challenges, opportunities and choices which it faces.

Our current membership includes: CEA (F) ;EV Group (A) Philips (NL); Micronit (NL); Danaher (USA); Dolomite (UK) ; Fluigent (F); HP (USA); Corning (USA); Dublin City University (IRL) and Fraunhofer (D), Lonza (CH) ; Philips (NL); Plastic Design Corporation (USA); Qiagen (CH); IMT (CH), Labcyte (US), and University of Cambridge (UK).

We organize closed meetings for our members on both sides of the Atlantic where we seek to promote our mission “to grow the market for microfluidics enabled products and services” by

- Finding shared interest across the landscape of applications - Championing modularity and standards where appropriate - Engaging with key industry influencers

While helping our members to do deals along the way.

With the support of the Knowles Laboratory at the University of Cambridge on this occasion as well as our closed session on Oct 11th we are also reaching out to selected guests in Europe and beyond our membership in an Open Meeting on Oct 12th seeking to engage them in our vision, projects and thinking.

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Location: St John’s College, Cambridge

A combination of the traditional and the modern, the 16th and 17th Century courts blend attractively with the 20th Century Cripps and Fisher Buildings. The renowned Bridge of Sighs leads to the 19th Century Gothic New Court which stands at the end of an expanse of grass and trees beside the river.

St John’s College is one of the largest of the University’s residential Colleges. The serene atmosphere of the ancient courts is complemented by the comfort, spaciousness and convenience of its modern accommodation. The Fisher Building, opened during the summer of 1988, has several meetings rooms and a large 250 seat lecture theatre, all of which are equipped with the very latest audio-visual and presentation technology.

Oct 11th (closed day, members only!) Castlereagh Room

09:15 Registration

09:45 Welcome

10:00 (Session brought forward to fit with speaker schedule!) Tuomas Knowles

We are an interdisciplinary and interactive group based in the Department of Chemistry, the Cambridge Centre for Protein Misfolding Diseases and the Cavendish Laboratory in Cambridge. We bring together ideas and tools from Chemistry and Physics to develop new approaches to probe the behaviour of biological molecules. We are particularly interested in protein self-assembly, the processes by which proteins come together to form the nanoscale machinery of life. Much of our efforts in this area are focused understanding aberrant protein self-assembly that underlies neurodegenerative disorders such as Alzheimer's and Parkinson's disease, and we conduct this work in the Cambridge Centre for Protein Misfolding Diseases. We are also interested in controlling the self-assembly of natural proteins to generate new types of functional materials.

The techniques used in our laboratory include microfluidics, protein chemistry, biosensors, optical lithography and scanning probe microscopy and spectroscopy. We also have an interest in applying theoretical concepts from statistical mechanics and chemical kinetics to protein systems.

We work both with natural and synthetic polymers and our interests range from fundamental biophysics to technological applications in materials science and molecular medicine.

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11:00 Scene Setting / Introductions

Peter Hewkin, CEO of Centre for Business Innovation who facilitates the MF8 consortium will introduce

delegates and set the scene for today’s meeting.

11:20 Break - Coffee

11:40 Session 1 (Research Enabled by Microfluidics)

Shery Huang - On-Chip Microvessel Platform for Cancer Invasion Studies

A microvessel in vitro model, based on an extracellular matrix (ECM) integrated microfluidic chip, is presented for straightforward injections of collagen gel and cells (HUVECs) inside the chip. The confined channel size results in a rounded vessel (~100 µm in diameter), instead of a rectangular vessel. The convenient device setup facilitate live cell image acquisition, and statistical analysis of the 3-dimensional cell-microenvironment interaction. Based on this device, we visualise the cancer extravasation dynamics in regional microenvironments.

Shery Huang has completed a MEng degree in Materials Science and Engineering from Imperial College London in 2007. With a Cambridge Gates Scholarship, she then pursued a PhD in Physics at Cambridge, focusing on carbon nanotechnology. She was a visiting researcher at the University of Texas at Austin (2008). After graduating from her PhD in 2011, she was awarded an Oppenheimer Fellowship and a Homerton College Junior Research Fellowship. Since Aug 2013, she has become a University Lecturer in Bioengineering in the Department of Engineering, University of Cambridge. Her research group 'Biointerface', is driven by translational bioengineering research, focusing on 3D bioprinting/ biomicrofabrication, and developing biomimetic organ-on-chips for high throughput drug testing.

Prof Ulrich F Keyser – Technique for Quantifying Drug Transport with Microfluidics

Ulrich Keyser studied physics in Braunschweig and Hannover, and after his PhD in low-temperature quantum transport joined the group of Cees Dekker at TU Delft from 2003 – 2006. After a short intermezzo as Emmy Noether research group leader in Leipzig, he was appointed as lecturer (Assistant Prof, 2007), Reader (Assoc. Prof, 2014) and Professor at the Cavendish Laboratory, University of Cambridge. His research group is consisting of 15 members. The main research is focussed on the physics of membrane transport, controlling molecules in nanopores and mimicking and understanding protein channels in microfluidic channels. His experimental group uses single molecule, nanopore sensing, DNA (origami) self-assembly, optical tweezers and microfluidics. He was awarded an ERC Starting Grant 2010-2015 and ERC Consolidator Grant (2015-2020). With the recent one he will design and understand novel nanopores using DNA self-assembly techniques to enhance molecular transport.

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12:45 Lunch / Networking

13:30 Microfluidics Hotseat

Pitches from microfluidics start ups seeking to engage

with the MF8 Consortium

RAB Microfluidics

Microfluidics is a robust platform that enables the automation of centuries of wet chemistry protocols, hence has increasingly been used as a tool deliver point-of-care diagnostics and in the process created a £3bn industry within life sciences, pharmaceuticals and medicine. But has this focus been too narrow? As with point-of-care diagnostics, there is a seemingly strong appetite for point-of-need analysis of petroleum fluids. Applications such as flow assurance monitoring, pipeline and refinery feedstock assessment, machine oil condition monitoring etc. have relied too long on stationary laboratories for crucial information. This has made operations that rely of such information inefficient, expensive, inconveniencing and environmentally unfriendly. Indeed, microfluidic technology can revolutionise the way petroleum analysis is carried out, making this process automated, mobile and rapid. RAB-Microfluidics is pioneering development of a product to enable the real-time, continuous monitoring and analysis of petroleum fluids. This will give benefits of early detection of problems, predictive analysis, rapid decision making to scientists, engineers and operators while improving cost effectiveness and enhanced efficiency within industrial businesses. Certainly, for petroleum fluid applications, there is the potential to create a £250mn market for mobile analytical technologies by 2021 and microfluidics can drive this.

Each Pitch to be followed by Q & A + feedback Chatham House Rule Applies!

14:00 DNA and Data

Building on members interest in business opportunities at the interface between microfluidics and data, we

will be looking at the way in which next generation DNA read-write technologies might usher in a new

paradigm for computing.

Invited Expert Witness: Michael Quail – Wellcome Trust Sanger

Institute

Senior Staff Scientist within the DNA pipelines Research and Development Group with extensive knowledge, experience and skills in NGS (Illumina, PacBio, Ion Torrent, Oxford Nanopore), library preparation, molecular biology and automation.

My role at Sanger is to enable our DNA pipelines to meet the requirements of the Institute and the scientists within it.

I am involved in,

Evaluation and optimisation of existing and emerging sequencing technologies.

Evaluation and optimisation of library preparation protocols. Developing applications and optimising to achieve cost savings, improved performance, and to enable them to be performed reliably within our high throughput sequencing teams.

Evaluation and optimisation of ancilliary equipment including liquid handling automation, to enable more efficient sample handling and processing.

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14:45 Patent Landscape as a guide to future priorities

At MF8.4 (MIT) the question arose ‘where should the consortium go in the coming year?’ and the

suggestion was put forward that we might use a patent landscape to help us make this decision.

PATSnap has offered to provide some insight into geographic, organisation and application ‘hot spots’ in

the relevant IP landscape. They will also have a demo table at the Open Day.

Invited Expert Witness: Dr Ali Hussein PatSnap

Dr. Ali Hussein has a deep focus on unlocking the insights that big data and

empowering decision-making workflows for the ‘citizen innovator’ by

simplifying the analysis of big data

At PatSnap, he is passionate about upgrading innovation workflows, and the

application of disruption innovation that software can empower across

technology areas. After starting his career in biopharmaceutical research, he

conducted his PhD at Imperial College London and the University of Bath in

the conversion of waste plant biomass to commercially valuable organic

compounds. For this research, he was honoured with the Annual Society for General Microbiology prize.

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15:15 Discussion - Homework

- Member priorities

- Review of Standards work

- Next meeting (Amsterdam December)

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15:45 Transfer to: Option A: Dolomite Microfluidics …. Transfer details to follow

visit to Dolomite Microfluidics (Royston) located 40mins from Cambridge we will organize

transportation according to demand. Please let CfBI know if you wish to take up this option.

The Microfluidics consortium has a tradition of visiting leading Microfluidic Institutions and

Businesses around the world. In keeping with the tradition, the October 2016 visit will be to

Dolomite.

Arrivals Those will independent transport please make your way to Dolomite’s Office Building at:

27 Jarman Way

Royston

Herts

SG8 5HW for 16:15

Transport (in the form of ride share with Peter Hewkin and Max Drobot) will take delegates from the St

John’s College meeting site to Dolomite’s Head Quarters in Royston. We will leave at 3:45 PM for the 30

minute drive to Dolomite. We will travel back to central Cambridge, leaving Dolomite at 5:45 PM.

The open house will include: a welcome update from Max Drobot, highlighting the new developments from

Dolomite as part of the Blacktrace Group.

- Key Applications

- Novel Product Development

- Microfluidics in Life Sciences

- Nanoparticle Synthesis

Established in 2005 as the world’s first microfluidic application centre, Dolomite focused on

working with customers to turn their concepts for microfluidic applications into reality.

Note: This session is also open to non-members who have signed up for the Open Day on Oct 12!

15:45 Transfer to: Option B: Fluidic Analytics ..Transfer details to follow

Fluidic Analytics was formed in 2013 as a spin-out from the Department of Chemistry at the University of Cambridge.

Our roots stretch back to a group of scientists who were inspired by the roles that proteins play in the biological world, driven to understand more about how proteins behave and function, but frustrated by the lack of suitable tools for protein characterisation. So they decided to invent their own.

Our vision is that protein science will transform our understanding of how the biological world operates in real time. We believe that this transformation will be every bit as revolutionary as the way that advances in DNA sequencing have transformed our understanding of how the biological world operates over decades, lifetimes and generations. And we believe that Fluidic Analytics can help make this vision a reality by developing products that enable easier, faster, more convenient and more accurate protein characterisation, whether in the lab, at the bedside or in everyday life.

Option A: 15minute walk details here and in the Logistics Section Option B: Taxi (call 01223 715715)

Note: This session is also open to non-members who have signed up for the Open Day on Oct 12!

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17:45 Close / Transfer to St Johns’ College MF8 Members Dinner

MF8 Members Dinner

Location: The Wordsworth Room St John’s College Cambridge

18:30 Drinks – and opportunity to visit the bridge of sighs,

chapel and other notable features of St John’s College

19:00 Dinner

This is an opportunity for Members to dine and network in private in

exclusive surroundings. Over dinner we will be addressed by

Professor Nicole Pamme to stimulate round table discussion about

new opportunities for microfluidics and how the MF8 consortium

might facilitate their realisation.

Nicole Pamme, Professor, The University of Hull

Prof. Nicole Pamme holds a chair in Analytical Chemistry at the University of Hull (UK)

and Director of Research for the School of Mathematics and Physical Sciences. Her

research activities focus on Lab-on-a-Chip devices for pharmaceutical, clinical and

environmental analysis, biomedical research with tissue-on-a-chip devices as well as

process integration and material synthesis in collaboration with Chemistry, Engineering

and Biomedical Sciences. She has authored >100 peer reviewed publications, patents

and book chapters in this area. Prof. Pamme has served on the programme committee of the microTAS

conference since 2008 and chaired the microTAS 2016 conference in Dublin. She sits on the Board of

Directors of the Chemical and Biological Microsystems Society (CBMS) and on the Advisory Board for Lab

on a Chip (RSC Publishing). Her teaching activities include lectures on microanalytical and forensic

chemistry as well as biosensors; Nicole has also co-authored a textbook for UG students on Bioanalytical

Chemistry. Nicole Pamme obtained a Diploma in Chemistry from the University of Marburg (Germany) in

1999. For her PhD studies she went to Imperial College London (UK) where she joined the group of Prof.

Andreas Manz. It was here that she first started working with microfluidic devices, more specifically, on

single particle analysis inside microfluidic channels. In 2004, she moved to Tsukuba (Japan) as an

independent research fellow in the International Centre for Young Scientists (ICYS) based at the Japanese

National Institute for Materials Science. She was appointed as a lecturer in Hull in December 2005

The CfBI team will be on hand to help with introductions

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October 12th (Open day, for non-member day-delegates - with member demos

and talks)

Location: Boys Smith Room St John’s College Cambridge

Open Day Delegates register and pay here. http://www.cfbi.com/mf74paymentpage.htm Table-top demos will be on show in the networking area from the following MF8 member organisations:

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9:00 Registration, Networking, Table-Top Demos

9:30 Welcome and Introduction to the MF8 Consortium - Peter Hewkin

(Centre for Business Innovation)

Peter Hewkin has led the MF8 consortium for 8 years and is responsible for the

delivery of its mission to grow the market for Microfluidics enabled products and

services. He will describe the processes which the consortium uses, the successes

which it has achieved and the ideas it has for the future.

10:00 Session 1 – Manufacturing Options

In this session we will compare and contrast manufacturing options for Microfluidic Devices

highlighting performance, batch size, regulatory and economic implications. Members of the MF8

consortium will be available at their table-tops with samples to talk about their options and

possibilities

EVGroup: (A) Industrial Implementation of Nanoimprint Lithography

Bernd Dielacher: EV Group is a recognized technology and market leader for

wafer processing equipment. The company offers system configurations for R&D

and volume production as well as implementation, process and materials know-

how according to the customer’s needs. Key products include wafer bonding,

lithography and metrology equipment in addition to photoresist coaters, cleaners

and inspection systems. Furthermore, EVG is among the leading companies in the

world providing micro- and nanoimprint equipment capable of hot embossing, UV-

NIL and micro-contact printing. EVG’s technology can thus provide customers with

a total solution for microfluidic device fabrication.

“Fluidic Factory: Additive Manufacture” - Maxime Drobot head of products

Dolomite Microfluidics (UK / US).

Maxime will describe how prototype microfluidics chips can be created using

additive manufacturing techniques in your own laboratory.

Discussion: What option is right for me? How do I plan / choose?

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11:15 Break, coffee, networking, table top demos

11:45 Session 2 Latest Research and Applications for Microfluidics

Chengxun Liu : IMEC (B)- Microelectronic & optoelectronic toolbox for life science

Chengxun Liu is Senior scientist & Team leader for microfluidics technologies at IMEC (the Semiconductor Industry Research Organisation in Belgium). He works on new applications of microfluidics and standards for applications in healthcare and beyond.

The advancement of nanoelectronics and optoelectronics starts to allow a true

lab-on-a-chip with previously challenging scenarios, single molecule, rare cell,

digital processing, high throughput, multi-physics, etc. However, the

heterogeneous integration of one or more types of active components in

microfluidics is rather complicated compared to passive microfluidics such as

micro filters or inertial-flow cell isolators. Material compatibility, device physics,

surface chemistry, mass manufacturability and macro-to-micro packaging are all important considerations

to bring the integrated device from laboratory to industry. This talk will present the efforts made by imec

toward the selection and integration of microelectronic and optoelectronic components for lab-on-a-chip

applications.

Sammy Datwani : Labcyte (US) - Droplets

Design, develop and launch new products to expand the market capability of acoustic liquid dispensing. I direct, manage and lead internal and external research programs for R&D, systems, scientific and advanced developments to create new instruments and new products (plastic consumables and reagents) and other novel capabilities for the company. My unique skill set combines understanding fluid dynamics on the micro- and nanoscale, the knowledge of interactions of system components, interfacial transport, microscale reactors, electrostatics, solution and polymer chemistry, genomics, proteomics, single-cell analysis, advanced applications, instrument engineering, laboratory automation, modeling, microarraying, analytical methods and biological instrumentation.

The CfBI team will be on hand to help with introductions

Tools for Protein Scientists - Andrew Lynn : Founder, Fluidic Analytics (UK)

Proteins are the building blocks of life. They form the key components of cells, co-ordinate crucial biochemical processes and carry out the chemical reactions that allow the biological world to function.

By developing products that make protein characterisation faster, more precise, more convenient, more cost-effective and more accurate, Fluidic Analytics is striving to help scientists, healthcare providers and people everywhere to understand the world around them better.

13:00 Lunch, networking, table top demos

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14:00 Cell/tissue/organ on a chip

Update on techniques / infrastructure / standards which support close to in-vivo toxicology testing.

Dr David Hughes – CN Bio

CN Bio develops human organ-on-chip technologies: devices that enable the formation of miniature models of human organs in the lab. We provide products to the pharmaceutical industry and in the past 3 years have used our proprietary organ-on-chip models in drug discovery and drug safety programs with more than 25 pharmaceutical companies. CN Bio has also pursued research to develop disease organ-on-chip models with successful programmes resulting in novel models of non-alcoholic steatohepatitis and Hepatitis B virus infection.

Working closely with academic pioneers in the bio-engineering field, and backed by prestigious grant awards from sponsors including DARPA and Innovate UK, CN Bio continues to develop next generation organs-on-chips.

CN Bio was a co-recipient with MIT in 2012 of a $26M US Federal contract to develop a “body-on-a-chip”: our team being the first to meet the final program milestone of developing a 10-organ platform in May 2017

“Combining 3-D cell culture microspheres with fluidics to model pharmacokinetics in patients” – Dr Xunli Zhang University of Southampton

Dr Xunli Zhang is a Reader in Bioengineering and Deputy Director of Graduate School in the Faculty of Engineering and the Environment at the University of Southampton. His key expertise lies in the area of microfluidic technology and the application in biomedical engineering, in particular, related to cell-based bioanalysis, drug delivery systems and biomicrofluidics. The application is largely associated with therapeutic problems like patient specific design of microfluidic devices for cancer treatment, combating tuberculosis, and rapid diagnosis of allergic irritations. He has also been actively involved in the EPSRC funded Network for Anti-Microbial Resistance and Infection Prevention (NAMRIP) to address the increasing resistance that microbes display to countermeasures like antibiotics. His research has also found great potential for industrial applications via collaborations with e.g. GSK, DSTL, BTG and

others

14:45 Session 3 Operational Techniques for Microfluidics “Advanced Flow Control for Microfluidics” -Nour Yakdi: Fluigent, Inc. (F, US)

Nour is a technical sales manager at Fluidget.

Since 2006, Fluigent develops, manufactures and commercializes innovative microfluidic flow control and fluid handling solutions for laboratories, research units and industrials around the world Enabling full control of your microfluidic systems through pressure, flow and electrical monitoring, Fluigent technologies provide innovating solutions for all your microfluidic and lab-on-a-chip applications (droplet-based drug testing, chromatography, cell perfusion, flow chemistry, cells and parasites separation, dielectophoresis, highly viscous fluids and liquid air manipulations, gene

expression analysis in microdroplet, etc).

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“Microfluidic technologies for molecular diagnostics, cell-based assays and

immunoassays at the FPC@DCU" – Conor Burke

The FPC@DCU is Ireland’s first Fraunhofer Project Centre and a €5M jointly supported initiative of Science Foundation Ireland and Fraunhofer-Gesellschaft, Germany. Its focus is on the development of lab-on-a-chip platforms to high Technology Readiness Levels for decentralised biochemical monitoring applications, e.g., Point-Of-Care Diagnostics, environmental monitoring and quality control in biopharmaceuticals production.

Conor will present an overview of the novel technologies under development within the project centre. Many of the platforms leverage

the unique valving technology developed by Prof. Jens Ducrée’s group in DCU, which enables a significant enhancement in the complexity of sample prep protocols that may be implemented on centrifugal microfluidic platforms. These include nucleic acid extraction and purification, combinatorial mixing, single-cell analysis and multiplexed immunoassays.

15:30 Wrap-up and Details of next meeting (Amsterdam December)

15:45 Close of Open Day

Networking - Free time!

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Table-Top Exhibits (in the Networking Area)

Backed by a $26M US Federal contract to develop a Human body-on-a-

chip and building on technologies developed at the Massachusetts

Institute of Technology, CN Bio is one of the pre-eminent Organ-on-Chip

firms in this emerging field.

Established in 2005 as the world’s first microfluidic application centre, Dolomite focused

on working with customers to turn their concepts for microfluidic applications into reality.

Today, Dolomite is the world leader in solving microfluidic problems. With offices in the

UK, US and Japan, and distributors throughout the rest of the world, our clients range from

universities developing leading-edge analytical equipment, to manufacturers of chemical,

life sciences and clinical diagnostics systems.

Dolomite’s key strength lies in offering a complete service to customers from problem conceptualisation

and feasibility testing through to full instrument design and development. By Productizing Science™, we

have enabled customers around the world to develop more compact, cost-effective and powerful

instruments.

Dolomite also offers a Microfluidic Consultancy to develop a variety of versatile, complex and cutting edge

custom devices, available in exceptionally short lead times.

Whatever your microfluidic requirements and application, Dolomite is the right partner with the right

expertise!

For more information please contact us on +44 (0)1763 242491, info@dolomite-microfluidics.com or visit our website www.dolomite-microfluidics.com.

EV Group is a recognized technology and market leader for wafer

processing equipment. The company offers system configurations for R&D

and volume production as well as implementation, process and materials

know-how according to the customer’s needs. Key products include wafer

bonding, lithography and metrology equipment in addition to photoresist

coaters, cleaners and inspection systems. Furthermore, EVG is among the

leading companies in the world providing micro- and nanoimprint equipment capable of hot embossing, UV-

NIL and micro-contact printing. EVG’s technology can thus provide customers with a total solution for

microfluidic device fabrication.

Since 2006, Fluigent develops, manufactures and commercializes innovative

microfluidic flow control and fluid handling solutions for laboratories, research

units and industrials around the world

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Enabling full control of your microfluidic systems through pressure, flow and electrical monitoring, Fluigent

technologies provide innovating solutions for all your microfluidic and lab-on-a-chip applications (droplet-

based drug testing, chromatography, cell perfusion, flow chemistry, cells and parasites separation,

dielectophoresis, highly viscous fluids and liquid air manipulations, gene expression analysis in

microdroplet, etc).

Indeed, Fluigent has created the market of pressure-driven flow controllers for microfluidic applications and

low volume fluid handling. The products are based on the patented FASTAB technology optimizing stability

and responsiveness of the flow inside your microfluidic systems (chip, microarray, etc).

In addition to the FASTAB technology, Fluigent owns or licences a portfolio of patents worldwide covering

its core technologies in microfluidic flow control, Lab-on-a-chip devices, diagnosis and life science analysis

(cell capture, etc).

Fluidic Analytics develops next generation tools for protein science. Our fundamentally new steady-state laminar flow platform allows proteins to be characterised in solution, under native conditions, quickly, cost-effectively and accurately. This platform brings together–on a single disposable chip–all of the fundamental steps of protein analysis, delivering a “sample in – data out” workflow that is rapid, simple and involves minimal sample preparation. Our technology looks to facilitate studies that distinguish proteins in simple solutions, cell lysates, or even complex mixtures, like blood plasma, by

simultaneously and sensitively measuring their key properties such as concentration, size, molecular weight and charge. And because our technology works best in extremely small volumes under physiological conditions, even highly complex protein solutions will be characterised rapidly, in small sample volumes and without extensive sample preparation.

The Fluidic Analytics platform characterises the properties of biomolecules and their interactions using novel approaches enabled by microfluidics. Our platform analyses proteins in solution under native conditions, obviating the need for tagging or labelling proteins before analysis. Measurements are conducted in label-free aqueous conditions at physiological pH, meaning that proteins and their interactions are assayed in their native conformations and without artefacts introduced by bulky tags or surface interactions. Applications of our platform include rapid size and concentration measurements, the detection of folding/unfolding, binding events, oligomerization, or aggregation, and binding constant determination.

The versatility of our platform and its compatibility with physiological conditions and native states give our technology the potential to make it easier, more accessible and more accurate to characterise the key characteristics of proteins that make our biological world function.

Micronit Microfluidics mission is to design, develop and manufacture custom

made microfluidic components based on micro- and nanotechnology.

Micronit provides added value to customers and end-users by offering a unique combination of micro technologies, materials, microfluidics knowledge

and customer application know-how, which enables Micronit to provide innovative and sustainable solutions.

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Open Day Registrations from:

Name Surname Organisation Udo Adels Qiagen D

Rotimi Alabi RAB UK

Jim Ballesty Enplas UK

Richard Biljard Technogation NL

Hermann Blok Micronit NL

Bojan Boskovic CfBI UK

Stephen Burgess University of Cambridge UK

Conor Burke Dublin City University EI

Jehangir Cama University of Cambridge UK

Ronan Daly University of Cambridge UK

Sami Datwani Labcyte US

Bernd Dielacher EV Group A

Devin Donnelly Labcyte EI

Maxime Drobot Dolomite UK

Max Focke Qiagen D

Gabrielle Giovanni Infumix I

Geoff Goodell University of Oxford UK

Robert Gunn Oxford Instruments UK

Richard Hammond Cambridge Consultants UK

Elaine Harries Dublin City University EI

Peter Hewkin CfBI UK

Alice Hewkin CfBI UK

Shery Huang University of Cambridge UK

David Hughes CN-Bio UK

Ali Hussain Patsnap UK

Tadas Kartanas University of Cambridge UK

Sam Keltie Royal Society of Chemistry UK

Ulrich Keyser University of Cambridge UK

Tuomas Knowles University of Cambridge UK

Darin Latimer Danaher US

Antone Lidell Lee Products UK

Chengxun Liu imec B

Chris Lowe University of Cambridge UK

Eric Lucien Picodrill CH

Andrew Lynn Fluidic Analytics UK

Roger Millington Sagentia UK

Despina Moushou University of Bath UK

Simon Norman Sagentia UK

Nicolle Pamme University of Hull UK

Eduard Pellsers Philips NL

Michael Quail Sanger UK

Kadi Saar University of Cambridge UK

Prodeep Sarker Barisal Biotech UK

Michael Shaich University of Cambridge UK

Ashok Sinha Enplas UK

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Peter Templeton CN-Bio UK

Alexios Tzannis IMT CH

Henne v Heeren Enabling NMT NL

Remi Wache IPGG F

Laura Winnan Patsnap UK

Nour Yakdi Fluigent F

Xunli Zhang University of Southampton UK

Pavel Zhurauski Zimmer and Peacock UK

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Logistics:

Delegates are responsible for making their own travel and accommodation arrangements. Please tell CfBI

how you plan to travel and where you will be staying so we can offer taxi/transfer shares. The information

below will facilitate this.

Cambridge is located 50 miles North of London and is easily accessible by road (M11), rail (London King’s

Cross / St Pancras – trains every 30 mins, journey time circa 50mins) and air.

For international delegates CfBI strongly recommends travel via London Stansted, London City

airport, Luton Airport or Eurostar (i.e. NOT Heathrow!)

Once in Cambridge, the meeting venues hotels and dinner site are all within walking distance of each other.

Approximate travel times from Cambridge

London Stansted Airport (car) - 30 mins; (train) – 35 mins

London Luton Airport (car) – 50 mins; (train) – 90 mins (via London Kings Cross/St Pancras)

London Heathrow Airport (car) – 90 mins; (train) – 120 mins (via Underground and Kings Cross)

London Gatwick Airport (car) – 100 mins; (train) – 120 mins (via Thameslink and Kings Cross)

London King’s Cross station / London St Pancras Eurostar station (train) – 50 mins (see departures to

Cambridge or Kings Lynn)

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Accommodation:

Although you might find cheaper accommodation outside town, driving in during the rush hour will be an

expensive nightmare. The following selection of Hotels are all within 10 minutes walk of the MF8 venues:

CfBI Recommendation

Varsity Hotel and Spa

Thompson's Lane (off Bridge street),

Cambridge

CB5 8AQ

Tel: +44 (0)1223 30 60 30

Overnight Inc Breakfast Circa £160

Other hotel recommendations:

Arundel House Hotel

Chesterton Rd

Cambridge

CB4 3AN

Phone: 01223 367701

Overnight including breakfast: circa £120

Saver Options

If you are on a really tight budget take a look at Travellodge

(Newmarket Road) or IBIS (at Cambridge Station) these are

slightly further out but a few £ cheaper!

It is possible for MF8 members to make use of a small number of college rooms within St John’s

College itself on a bed and breakfast basis on the night of Oct 11. Note this is not a full service hotel – but

it is a unique experience. If you are interested in this please ask kari on operations@cfbi.com well in

advance!

Car Parking is not easy in Cambridge. The nearest car park to St Johns College is Park Street. However

this is often full and not cheap if you manage to get in. Delegates might want to consider Park and Ride or

Taxi!!

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Meeting Venue and Hotels Location in Cambridge:

To M11 Motorway (London)

St John’s College Varsity Hotel and Spa

(dinner and meeting venue)

Looking for nearby pubs? We recommend:

The Mitre : 17 Bridge Street - Close by

The Punter: Pound Hill - Worth the walk

The Castle Inn: 38 Castle Street - Worth the walk

Railway Station: For

London King’s Cross

(50mins) and Stansted

Airport (35 mins)

Travellodge

Hotel

Arundel House

Hotel

Car Park

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Location – inside St Johns College

Pedestrian Entrance Fisher Building (day time meetings)

Pedestrian Entrance (from City) Dinner Location

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Walking Route Option – 15mins to FluidicAnalytics (or you can take a taxi)

Questions?:CfBI staff are available before or during the Microfluidics Consortium Meeting to help with

delegate queries. operations@cfbi.com or 07951721110

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