Metastatic colorectal cancer:from disease biology toclinical management6-8 July 2016 - Naples, Italy

PRACTICE TEACHING COURSESCIENTIFIC PROGRAMME

1

OverviewThis educational activity is aimed to medical oncologists who want toenlarge their knowledge on the biology of colorectal cancer, tobecome familiar with molecular pathology of colorectal cancer and toexplore new systemic treatments for metastatic colorectal cancer(mCRC) patients. With this in mind, small groups of participants, withhomogeneous level of knowledge and experience in the treatment ofmCRC will be involved. The preceptorship course will include differentsessions, specifically dedicated to the molecular biology of colorectalcancer, the current standard of care for mCRC patients and the recentdevelopments in colorectal cancer basic and translational research.

Learning objectivesBy attending this practice teaching course, participants will be able to:

• Describe the current knowledge of molecular biology of colorectalcancer

• Review the standards of care for metastatic colorectal cancerpatients

• Define major achievements in basic and clinical research oncolorectal cancer

Target audienceMedical oncologists with experience in the management of metastaticcolorectal cancer, who want to enlarge their knowledge on the biologyof the disease and on the latest developments in colorectal cancerbasic and clinical research.

ChairFortunato CiardielloSecond University of NaplesNaples, Italy

Metastatic colorectal cancer: from disease biology to clinicalmanagement

CME ProviderEXCEMED is a non profit foundation dedicated, since the last fourdecades, to the development of high-quality medical educationprogramme all over the world.EXCEMED adheres to the guidelines and standards of the EuropeanAccreditation Council for Continuing Medical Education (EACCME®)which states that continuing medical education must be balanced,independent, objective, and scientifically rigorous.

Continuing medical educationEXCEMED (www.excemed.org) is accredited by the EuropeanAccreditation Council for Continuing Medical Education (EACCME®) toprovide the following CME activity for medical specialists. The EACCME®

is an institution of the European Union of Medical Specialists (UEMS),www.uems.netThe CME course “Metastatic colorectal cancer: from disease biologyto clinical management” held on 6-8 July 2016 in Naples, Italy, isdesignated for a maximum of 13 (thirteen) hours of European CMEcredits (ECMEC). Each medical specialist should claim only those creditsthat he/she actually spent in the educational activity. EACCME® creditsare recognized by the American Medical Association (AMA) towards thePhysician's Recognition Award (PRA). To convert EACCME® credit toAMA PRA category 1 credit, please contact the AMA.

EXCEMED adheres to the principles of the Good CME Practice group(gCMEp).

2

General information

VenueThis course takes place at the:

Second University of NaplesVia Pansini 5 - II PoliclinicoBuilding 3 - 4th floorNaples, Italy

LanguageThe official language of this course is English.

CME ProviderEXCEMED - Excellence in Medical Education

Senior Programme Manager: Alessia AddessiT +39 06 420413 591 - F +39 06 420413 677alessia.addessi@excemed.org

Medical Advisor: Cristina Raimondi cristina.raimondi@libero.it

For any logistic support please contact: Meridiano Congress InternationalSenior Project Manager: Federica RussettiT +39 06 88595 209 - F +39 06 88595 234 federica.russetti@meridiano.it

3

https://twitter.com/EXCEMED_Onco

www.facebook.com/excemed/

www.linkedin.com/company/excemed---excellence-in-medical-education

5

Fortunato CiardielloSecond University of NaplesNaples, Italy

Francesca FioreSecond University of Naples Naples, Italy

Erika MartinelliSecond University of Naples Naples, Italy

Teresa TroianiSecond University of Naples Naples, Italy

Faculty

Programme

7

Wednesday, 6 July 2016

09.15 Welcome and visit of the centerF. Ciardiello (Italy)

10.15 Teaching session IL1: Molecular biology of colorectal cancer

E. Martinelli (Italy) - T. Troiani (Italy)

10.45 Question time

11.00 Coffee break

11.30 Teaching session IIL2: Molecular pathology of colorectal cancer: tissue

E. Martinelli (Italy) - T. Troiani (Italy)

12.00 L3: Teaching session IIIMolecular pathology of colorectal cancer: liquidbiopsy E. Martinelli (Italy) - T. Troiani (Italy)

12.30 Question time

12.45 Lunch

13.45 Practice session IHow to trace a reliable molecular profile ofcolorectal cancer patients (visit to laboratories dedicated to the molecularanalysis of colorectal cancer) E. Martinelli (Italy) - T. Troiani (Italy)

14.45 Interactive discussion I(participants and local experts will share theirexperience in the field of molecular characterizationof colorectal cancer)E. Martinelli (Italy) - T. Troiani (Italy)

15.45 End of the first day

Legend:

: Journal club

L : Lecture : Question time : Site visit : Interactive discussion

8

Thursday, 7 July 2016

09.00 Practice session IIDay hospital activities F. Ciardiello (Italy) - E. Martinelli (Italy) - T. Troiani (Italy)

10.30 Coffee break

Teaching session IV: Standards of care for metastatic colorectal cancer

11.00 L4: First line treatmentsF. Ciardiello (Italy)

11.20 L5: Beyond the second line and optimal treatmentsstrategiesE. Martinelli (Italy) - T. Troiani (Italy)

11.40 L6: Improving medical communication strategies incancer careF. Fiore (Italy)

12.00 Question time

12.15 Practice session IIIOutpatient visitsCommunication in practice F. Fiore (Italy)

13.15 Lunch

14.15 Teaching session VL7: Beyond the standards of care: open clinical trials for

metastatic colorectal cancer patients E. Martinelli (Italy) - T. Troiani (Italy)

14.45 Question time

15.00 Interactive discussion IIClinical cases (multidisciplinary team) and casesprovided by participants F. Ciardiello (Italy) - E. Martinelli (Italy) - T. Troiani (Italy)

16.30 End of the second day

Friday, 8 July 2016

09.00 Teaching session VIL8: Recent basic and translational research

achievements in colorectal cancerE. Martinelli (Italy) - T. Troiani (Italy)

09.30 Question time

09.45 Practice session IVHow to elaborate a basic or translational researchproject E. Martinelli (Italy) - T. Troiani (Italy)

10.30 Coffee break

11.00 Practice session VVisit to the laboratories dedicated to basic andtranslational researchE. Martinelli (Italy) - T. Troiani (Italy)

11.45 Interactive sessionJournal clubF. Ciardiello (Italy) - E. Martinelli (Italy) - T. Troiani (Italy)

13.15 End of the course

Lunch

9

Disclosure of facultyrelationships

10

EXCEMED adheres to guidelines of the European AccreditationCouncil for Continuing Medical Education (EACCME®) and all otherprofessional organizations, as applicable, which state thatprogrammes awarding continuing education credits must bebalanced, independent, objective, and scientifically rigorous.Investigative and other uses for pharmaceutical agents, medicaldevices, and other products (other than those uses indicated inapproved product labeling/package insert for the product) may bepresented in the programme (which may reflect clinical experience,the professional literature or other clinical sources known to thepresenter). We ask all presenters to provide participants withinformation about relationships with pharmaceutical or medicalequipment companies that may have relevance to their lectures. Thispolicy is not intended to exclude faculty who have relationships withsuch companies; it is only intended to inform participants of anypotential conflicts so that participants may form their ownjudgements, based on full disclosure of the facts. Further, all opinionsand recommendations presented during the programme and allprogramme-related materials neither imply an endorsement nor arecommendation on the part of EXCEMED. All presentationsrepresent solely the independent views of the presenters/authors.

The following faculty provided information regarding significantcommercial relationships and/or discussions of investigational ornon-EMEA/FDA approved (off-label) uses of drugs:

Fortunato Ciardiello Declared no potential conflict of interest.

Francesca Fiore Declared no potential conflict of interest.

Erika Martinelli Declared receipts of honoraria orconsultation fees from Lilly and Roche.

Teresa Troiani Declared receipt of honoraria or consultationfees from Bayer and Amgen.

11

Take a look at the new website

• Six specialty areas, including oncology

• Accessible and accredited e-learning packages

• A world-class repository of CME knowledge andlearning materials

• Monthly updates about our events and resourcesin oncology

• Register with us online and access it all – free

www.excemed.org

Better outcomes for patients start here.With over 40 years in the field, EXCEMED has been delivering CME-accredited programmes longer than any other provider

in Europe, and now offers CME worldwide.

ONCOLOGY NEUROLOGY CARDIOMETABOLIC REPRODUCTIVE MEDICINEIMMUNOLOGY ENDOCRINOLOGY AND METABOLISM SPECIALTY

AREA

LIVE EVENTS LEARNING RESOURCES ONLINE COURSES NEWS

AN EXCLUSIVE FOCUSON CME

Our core mission is to help physicians achieve the best possible outcomes for patients. Our name,EXCEMED, symbolizes a drive for excellence and reflects a passion for delivering the

absolute best in CME. With four decades of achievement behind us and access to the world’spremiere medical experts, better outcomes for patients start here. About EXCEMED.

12

All EXCEMED programmes are organized solely to promote the exchangeand dissemination of scientific and medical information. No forms ofpromotional activities are permitted. There may be presentations discussinginvestigational uses of various products. These views are the responsibility ofthe named speakers, and do not represent an endorsement orrecommendation on the part of EXCEMED. This programme is madepossible thanks to an educational grant received from Merck KGaA,Darmstadt, Germany

EXCEMED - Excellence in Medical EducationHeadquarters14, Rue du Rhône - 1204 Geneva, SwitzerlandRepresentative OfficeSalita di San Nicola da Tolentino 1/b - 00187 Rome, ItalyT +39 06 420413 1 - F +39 06 420413 677

Copyright © EXCEMED, 2016. All rights reserved.

Improving the patient's life through medical educationwww.excemed.org