Medicine MCQs

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    MEDICINE & ALLIED 4th JUNE 2014 (Paper A & B – Mixed)

    NOTE: ALL MCQs are recall questions. Human error is Possible.

    Special Thanks to Dr Sahil Syed, Dr Hammad, Dr Jawad, Dr Suleman Sami, Dr

    Qamar Subhan, Dr Umbreen Hashim & Members of FCPS Prep 2005-2010

    group of FB.

    Good Luck for your Result. May ALLAH help you all (aameen)

    ●●●●●●  ●●●●●●  ●●●●●●  ●●●●●●  ●●●●●● 

    1. MRSA sensitive to: 

    aztreonam

    co amoxiclav

    clotrimoxazole 

    metronidazole

    2. primary hepatocellular carcinoma : aflatoxin b1

    hep E

    hep C 

    alpha 1 antitrypsin deficiency

    3. Braodman area 3 1 2

    1 recieves all somatic sensation 

    2 special sensory

    3 granular cortex something

    4. serology not helpful in 

    a) toxoplasmosis

    b) ambisis

    c) giardiasis 

    d) ameobic liver abscess

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    5. Virus causes cancer via 

    1 proto oncoogene

    2 oncogene 

    3 nucleic acid

    4 promotr gene

    6. Byssinosis occurres in people working in 

    1)garment factory

    2)lead factory

    3)textile industry 

    4)cement factory

    7. OPD , 2 year old boy comes with fever, bowel disturbance... mcv mch

    mchc all raised ... detected by 

    serum vit b12 levels 

    intrinsic factor antibodies

    8. 1st line phagocyte in blood 

    neutrophil 

    monocyte

    macrophage

    9. old aged Person living at 12000ft had a hx of of MI 6 year back...both

    lower limbs swelling and bluish discoloration ...cause 

    A. cardio-pulmonary failure 

    B. venous thrombosis

    C. CO Poisoning

    10. a lady delivered 34 weeks baby who was at 30th percentile of weight

    and height, cleft lip cleft palate, microcephaly , 6 fingers in both hands ...

    axial something ... whats the diagnosis :

    a: 45X

    b: 46XXy

    c: 74 XY+13 

    d: 74 XY + 18

    11. Esophageal stage of swallowing most effected by : 

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    myasthenia

    cerebral cortex stroke just above lateral gyrus

    Scleroderma

    12. cancer cells combatted by : 

    natural killers (BOTH NK cells & CD8 are Anti-Neoplastic)  

    cd8 and t lymphos

    cell mediated

    13. TCA.... what is false: 

    A. sedation

    B. alpha blocker

    C. Sympthomimetic 

    D. beta agonist activity

    14. DIC is stimulated by?? 

    tissue thromboplastin 

    15. Thiazides causes.. 

    Hypokalemia 

    Hyponatremia

    Hypocalcemia

    16. Hyperpolarization is caused by.. 

    Na+ influx

    K+ influx

    Cl- influx 

    17. Pt of chronic renal failure going to dialysis..normocytic normochromic

    anemia .. Drug given:

    Erythropoietin

    Frolic acid

    Vit b6

    Vit b12

    18. Tricuspid auscultation area? 

    A. 2nd right ic space

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    B. 2Nd left ic space

    C. 3Rd left ic space

    D. Mitral area

    E. Lower half of left border of sternum 

    19. Parotid ducts opens into (Asim MCQ)

    Second upper molar teeth between cheeks and teeth 

    20. Histamine releasing opioid analgesic. 

    A. Morphine 

    Tramol

    butyrophenie

    fentanyl

    21. vitamin b12 def can be found out by urine test of

    methylmalonic acid 

    pyruvic acid

    22. a patient known case of lambago comes with sudden left side chest

    pain.. Cardiac enzymes r normal.. No retrosternal pain also not radiated..

    But tenderness at 5,6 intercostal spaces at posterior side.. 

    MI

    Costochondritis 

    Aortic aneurysm

    Pleuritis

    23.

    There is lesion of upper trunk.. All wil occur except (Asim’s MCQ)adduction of arm

    medial rotation of arm

    Sensory loss over forearm

    Elbow extension

    Supination 

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    24. Typhoid diagnose in 2nd week best by : 

    widal

    blood cs

    blood cs plus widal 

    only widal

    stool cs

    25. Pt with nose lesion , granuloma, proteinuria 

    leprpsy

    wegner's 

    26. Which hormone not required for growth of sperm:

    GH 

    bHCG

    Prolactin

    FSH

    27. Steatorrhea due 2 chronic pancreatitis occur due to deficient: 1,amylase 

    2.lipase 

    28. Female with lush push bodyline , well develped brest ,, complained

    amenorrhoea since puberty , short vagina , uterus not palpable, testes in

    inguinal region. 

    male psuedohermaphrodite

    female pseudoherma

    testicular feminization 

    29. Dissection of aorta: 

    medial necrosis (Cystic Medical Necrosis – Rubin’s Pathology)  

    30. Subclavian artery arches over: (Asim’s MCQ)

    clavicle

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    1st rib 

    2nd rib

    31. What’s the hallmark of aids: 

    progressive immune-depression 

    opportunistic infections

    32. in tractus solitarius 

    A. 1st order neuron of taste (ant 2/3 tongue)

    B. 2nd order neuron of taste (ant 2/3 tongue) 

    33. wound healing 

    ascorbic acid 

    34. Autosomal dominant. whats wrong: 

    50% offspring effected

    complete penetrance

    50% females effected

    Variable expression

    35. radiation causes cancer usually in : 

    A. 5-10 yr 

    B. more than 10 yrs 

    36. what white blood cells are raised in acute viral infection

    A. Neutrophils

    B. Lymphocytes 

    37. protein fat carbohydrates deposition by 

    A. GH

    B. glucagon

    C. insulin 

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    38. Appendix ..pain in flexion & Medial Rotation of hip. (Asim & Shoaib MCQ) 

    A. Pelvic 

    B. Retrocecal

    C. Preileal

    D. Post ileal

    39. body utilizs nutrients in what order: 

    CHO, fats , protein 

    fat, prot CHO

    cho Prot fat

    40. myasthenia gravis Pt, Dr gv some medication due to which Pt conditions

    improved. What’s mode of action of medication: 

    anticholinesterase 

    chlonergic

    anticholinergic

    41. Skeletal muscles 

    A. are innervated by somatic nervous system 

    B. are non straited

    C. intercalated disc

    42. Shock characteristic:

    tissue hypoxia 

    low BP

    tachycardia

    43. Scenario about nerve supply to tip of the nose 

    Opthalmic division of trigeminal nerve 

    44. Neurogenic shock mediated by: loss of vasomotor tone 

    heart pumping decrease

    45. Scenario on lacrimation while eating like that 

    Facial nerve 

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    3. thrombin

    4. thromboplastin

    5. Prothrombin 

    54. Osteogenic imperfecta 

    Defect in synthesis of collagen

    55. liver in its place coz of

    attachment with IVC

    ligaments 

    56. Jugulodiagastric lymph node drains into 

    Palatine tonsils and tongue 

    57. Right adrenal gland 

    Pyrimidal in shape 

    58. oblique fissure in lung extends from : (Asim’s MCQ)

    t3 - t6 

    t2 t6

    t4 t6

    59. inappropriate about adrenal gland 

    neonate adrenal is same the size of adult adrenal gland 

    60. factor 9 def, aptt high PT low 

    Christmas disease 

    factor 8 def

    61. sixty year old lady having unilateral severe head ache...temporal atery

    biopsy 

    A. Giant cell artiritis B. Takayasu

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    62. bile acids 

    absorbed in ileum 

    63. bile acids helps fat digestion by: 

    Facilitate absorption of Lipid 

    Hydrolysis of LIPID

    64. stone in the parotid duct (Asim’s MCQ)

    Apoptosis 

    necrosis

    degeration

    65. Artificial respiration is not necessary if lesion occur at.. A.c2 B.c3 C.above

    c5 D.below c5

    66. epithelium changes in endocervix 

    Metaplasia 

    dysplasia

    67. Squamous cell Carcinoma 

    marjolin ulcer

    bowen's disease 

    68. Peroxisomes 

    Long chain fatty acid 

    69. Pt for renal transplant , what investigation is not necessary in the donor:

    (Asim’s MCQ)

    Serum Renin 

    UCE

    HLA

    CBC

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    70. Hormone involved in gluconeogenisis

    Glucagon 

    71. Inhibit gastric acid secretions (Asim’s MCQ) 

    Secretin 

    72. Naked Person with 80% humidity in air & 21 degree temp:

    heat loss by (Ganong’s MCQ: Ch# 17 MCQ#2) 

    A. conduction and radiation 

    B. By vaporization of sweat

    C. Elevated metabolism

    D. Respiration

    E. Urination

    73. Derived from neural crest (Asim’s MCQ)

    autonomic ganglia 

    74. Rapidly adopting fibers... A. baroreceptors, B. pacinian corpuscles, C.

    meissner

    75. Nutritional deficiency..scaly dermatitis,alopecia

    Zinc 

    76. Not supplied by vagus nerve (Asim’s MCQ)

    A. stomach

    B. ascending colon 

    C. Jejunum

    77. Which will shift the O2.HB curve to the extreme left... 

    A. CO poisoning 

    B. fetal Hb ,

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    C. acidosis,

    D. inc 2,3 bis

    78. Secretary vesicles found in organelle 

    A. Golgi apparatus (Transport vesicle from ER to Golgi   Modification of Transport

    vesicle inside Golgi   Secretary Vesicle)  

    B. ER

    79. Cristanee concavity toward nucleus

    Golgi apparatus 

    80. Inappropriate about atropine..

    A. Increase CUTANEOUS BLOOD FLOW 

    B contraindicated in inc intra-ocular pressure

    81. Widest part of epidural space 

    A. L2 

    B. C7

    82. About collagen.... most abundant protein in the body 

    83. High pressure oxygen for 24 hrs (Scenario of Some Smoker). 

    Spontaneous Pneumothorax 

    84. Warfarin given for DVT, what is Appropriate? 

    Not given in pregnancy 

    Rapidly antagonized by FFP

    85. 5th week what happens? 

    A. Heart has definite form (NOT True as Upper as it occurs at the end of 8 th week )  

    B. Limb buds appear (NOT True as Upper limb buds in 4 th week & Lower limb in 5 th )  

    In These options (If other 3 were wrong, then Option B is appropriate.)

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    93. Hormone that stores carbohydrates, lipids and proteins in cells is also

    called hormones of abundance 

    A. GH

    B. Cortisol

    C. Thyroid hormoneD. Estrogen 

    E. Insulin 

    94. Starling law of heart (Ganong’s MCQ: Ch#30, Q# 6) 

    A. Explain the increase in cardiac output that occur when venous return is

    increase 

    B. explain the inc in heart rate by exercise.

    C. does not operate during exercise.

    D. explains the increase in cardiac output when the sympathetic nerves supplying

    the heart are stimulated.

    E. does not operate in the failing heart.

    95. Trigeminal ganglia 

    A. Completely covered by dura

    B. Freely bathed in csf  

    C. Lies in MCF on the side of cavernous sinus 

    96. Short limb..short height...intelligence normal (case of achondroplasia) 

    A. Autosomal dominant 

    B. Autosomal recessive 

    97. Drug which enhances the hypoglycemic effect of sulphonylurea? 

    A. Phenylbutazone, (Ref: Textbook of Diabetes – Table 24-6)  

    B. thiazide.

    C. OCP

    98. Tx of hypercalcemia 

    A. Calcinomimetic

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      B. Bisphosph

    C. Furesimide 

    99. 45x0/46xy....A short stature n prominent crease line... 

    A. BRACHECEPHALY AND MENTAL RETARDATION

    B. GONADAL DYSGENESIS WITH FOLLICULAR APLASIA 

    100. Neostigmine action: inhibit Ach esterase 

    101. Venous return increased by

    A. intrathorcic pressureB. Valve in veins

    C. Muscle contraction of leg 

    102. A LADY HAD AN ROAD ACCIDENT AND GOT HEAD INJURY.SHE LATER

    DEVELOPED complaint of polydypsia and polyuria..lab findings were

    given in which urine osmolarity is low and plasma osmolarity high. After

    giving vasopressin urine osmolarity increased and plasma osomalilty

    decreased…what is diagnosis???

    A. Central Diabetes Insipidus 

    B. SIADH

    C. Nephrogenic Diabetes Insipidus 

    103. Chrons disease diff from Ulcerative colitis

    Perianal lesions 

    104. An immunocompromize pt developed s/s of pneumonia BAL fluid

    revealed boat shaped cyst organism (Nov 2013 Medicine paper MCQ = repeated)

    A) Toxoplasma gondii

    B) H. influenza

    C) Pneumocystis carinii 

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    105. Hormone inhibited by feedback from hypothalamus? Prolactin

    106. Pneumothorax 

    Ipsilatrral lung collapse and chest wall spring out 

    107. A patient burning and recovered completely what factor determines that

    complete recovery will occur? A. underlying

    Granulation tissue, B. local edema

    C. Blood supply

    108. Typhoid test (Asim’s MCQ)

    A. 1:160 O antigen

    B. 1:160 H ag

    C. 1:80 O ag

    D. 1:160 O and H antigen 

    109. Pt unable to invert his foot while the lateral rotation is intact structure

    involved 

    A. tibialis ant & tibialis post 

    B. tibials ant & fallicus H longus

    110. What happen in lower motor neuron lesion..?? A.

    muscle wasting.. B

    hypertonia..

    111. Vomiting center situated 

    Medulla oblongata 

    112. Lower motor neuron lesion 

    A. Decrease motor tone B. spastic

    113. Chorea, athetosis region involved 

    Basal ganglia 

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    121. Estrogen is released by? 

    A. ovary 

    B. uterus

    122. Which is malignant? 

    A. Glioma 

    B. Meningioma

    C. H. mole

    123. Clostridium perfingens exotoxin action by..

    A. coagulase .

    B. phopholipase 

    124. Pt with bronchial ca present with hemoptysis due to?? (Asim’s MCQ)

    A) Erosion of bronchial vessel 

    B) pulm vein

    C) pulm artery.

    125. Cavernous sinus thrombosis 

    A. superior opthalmic vein 

    B. inferior opthalmic vein

    126. Inappropriate about hcg.. 

    A. It causes ovulation..

    B. Little similar as thyroid,

    C. it causes LEUITINIZATION OF FOLLICLES

    127. major part of energy utilized during breathing is to overcome (Asim’s

    MCQ) 

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    A. Elastic recoil of lungs

    B. Resistance of chest wall

    C. Large airway resistance

    128. Side effect of chlorpromazine.. A. dystonia 

    129. Immunological function is significantly reduced in 

    A. dec basophils

    B. ACTH 

    C. dec neutrophis

    D. liver failure

    130. Patient came with complaint of hirsutism .muscle wasting .skin

    pigmentation and truncal obesity, hyprtension hyprglycemia...

    A.Cushing disease

    B. Primary inc in ACTH 

    131. Decrease in PR interval 

    A. 1st

     degree Heart Block

    B. 2nd degree Heart Block

    C. WPW syndrome

    132. Slow Pain transmitted by unmyelinated c fibers.. 

    A. substance p 

    B. serotonin

    C. Ach

    133. Which hormone decrease gastric motility..??? 

    A. CCK ..

    B secretin..

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    140. Aids not associated with.. 

    A squamous cell carcinoma..

    B lymphoid series of bone marrow (Leukemia is Unlikely in AIDS) 

    141. Lymph nodes not present in? 

    A. Spleen

    B. Thymus 

    142. Basic drugs bind to..?? (Chandkian’s MCQ with wrong key answer) 

    A. alpha 1 glycoprotein..

    B. albumin

    143. Thrombocytopenia APPROPRIATE 

    A. inc clotting time causing dec platelet count

    B. thrombocytonpenia impairs APTT pathway

    C. DIC occurs due to Dec in platelet count/ DIC causes decrease in platelet

    count 

    144. A child with thrombocytopenia after acute viral infection due to....

    A. Anti-platelet antibody (Explanation: In ITP Body own cells attack on

    Platelets – The reason why We give Steroids or do Splenectomy is because it is

    Autoimmune process and SPLEEN is the main culprit site. Antibodies Formed in SPLEEN

    BY Plasma Cells) . 

    B. immune complex formation.

    C. consumptional coagulopathy

    145. Minimal change in blood flow to an organ during exercise 

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    A) Heart

    B) Brain

    C) Skeletal muscles

    D) Kidneys.

    E) Lung.

    146. Congenital anomaly associated with urothelial CA is 

    A. bladder extrophy (Adenocarcinoma has association with B. Extrophy – Conn’s

    Current Therapy 2013) 

    B. unilateral agenesis of kidney

    C. double ureter

    D. Horse shoe kidney

    147. Lipoprotein with highest cholesterol content (Asim’s MCQ)

    A) HDL

    B) LDL 

    C) IDL

    D) VLDL

    E) Chylomicrons

    148. One question about leprosy drugs (Asked about Inappropriate

    statement):

    Answer = CLOFAZIMINE IS NOT GIVEN IN PT RESISTENT TO DAPSONE 

    149. Galactorrhea (Asim’s MCQ with little modification of question stem) 

    A. Chromophoes are smallest 

    B. chromophils are 50% of total

    150. Scenario of turner syndrome. 

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    A. bracheceephale with mental retardation

    short stature with prominent simian crease

    B. gonadal dysgenesis with follicular aplasia 

    151. Inappropriate about dopamine. 

    A: contraindicated in septic shock...

    B. causes increase myocardial infarct area..

    C. 10 microgram per kg dose of dopamine causes vasoconstriction

    a. Hyernatremia 

    A. heart failure 

    B. excessive ADH

    152. A vertical lesion in optic chiasma causes.. 

    A bitemporal hemiaopia..

    B. right sided homonomous hemianopia

    153. Warfarin causes decrease in..

    A. Fibrinogen

    B. Factor 13

    C. Prothrombin

    154. Essential amino acid is.. Phenylalanine 

    155. Atomic bomb,... release of Stroncium-90 which affect milk products..so it

    causes

    A.osteosarcoma 

    B.nasopharyngeak CA

    3.leukemia

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    156. Vertical artery along face, deep to submandibular gland is..??

    A. Facial

    B. Maxillary

    C. Lingual

    157. Tumor which also invade neural tissue 

    A.adenoCA

    B.hemangiopericytoma 

    158. which one is NOT autosomal recessive 

    A. ataxia talengiectasia

    B. carcinoma ovary 

    159. good patient and doc relationship...active listening 

    160. One glucose give ATP.. A. 38 (8 in Glycolysis & 30 from Kreb’s Cylce) | some folks

    are using FA as reference that it is 32 BUT it is NOT Correct. According to Modern

    P/O (Phosphate/Oxygen) ratio 1 NADH2 = 2.5 ATP & 1 FADH2 = 1.5 ATP. The sum of

    ALL ATPs, NADH2 & FADH2 produced by 1 molecule of glucose is equal to 31 ATPs

    (NOT 32) So again 32 is NOT correct. ALL Major Biochemistry Texts still follow the

    Traditional (Old) P/O ratio (NADH2 = 3ATP & FADH2 = 2 ATP) So Correct answer is 38 

    161. Digoxin don't cause 

    A. inc intracellular Ca

    B. inc intracellular Na

    C. inc intracellular K

    162. inferior thyroid artery is 

    branch of thyrocervical trunk 

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    163. Pt with gum bleed in petechia advised bone marrow likely DX 

    A) Lymphoma

    B) Leucopenia

    C) Leukemia 

    164. fluid having specific gravity of 1.006 cause is 

    A. CCF (Specific gravity less than 1.016 is Transudative)  

    B. Ca lung

    C. pneumonia

    D. TB

    165. a patient came in semi comatose state,,shifting dullness was

    positive..liver biopsy taken and there were mallory bodies n fibrosis of

    liver : Alcoholic Hepatitis 

    166. A lady after abdominal surgery presented with dyspnea susp DVT cause 

    (Asim’s MCQs)

    A) Endothelial injury

    B) Endothelial injury & stasis

    C) Stasis & hypercoagulablity.

    167. Broadman’s Area 3 2 1,,, 

    A. agranular cortex.. 

    B. Primary Somatosensory Cortex 

    168. secondary center of ossification (Asim’s MCQ) 

    EPIPHYSIS 

    169. acclimatized...rapid ascent 

    a) 2 3 DPG 

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    b) PO2 is normal

    c) PO2 is lower than normal

    d) Pulmonary edema

    170. Pregnant lady with normocytic normochromic Anemia. Cause? 

    plasma volume expansion

    171. Adrenal insensitivity syndrome which is inappropriate test 

    A. Serum LH FSH

    B. Serum progesterone 

    C. US abd

    172. Endocervical epithelium of lady reveals sq epi cause? 

    A) Dysplasia

    B) Anaplasia

    C) metaplasia 

    173. Water Intoxication causes??? (Asim’s MCQ)

    A) Slow pulse 

    B) Thirst

    C) Altered behavior.

    174. In complete heart block 

    A. Atrial rate is lower than ventricular rate

    B. Ventricular fibrillation is commonC. Fainting occur cuz atrial unable to pump blood into ventricles

    D. Fainting occur because of prolong periods during which ventricles fail to

    Contract (Ganong’s MCQs Chapter 29 Q # 5 24 th  Ed)  

    175. Burning hot sensation occurs when temp of the surrounding is 

    A.28

    B.32

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    C.42

    D. Above 45 (Thermal nocioreceptors activate when Temperature Falls Below 5 C – COLD or

    shoot Above 45 C)

    176. Slow growing Tumor/Carcinoma of Thyroid? 

    A. Follicular

    B. Papillary 

    177. Low molecular weight heparin 

    A) can cause thrombocytopenia

    B) produced by fragmentation n degradation of heparin 

    178. Clostridium tetani main site of action is?  A.

    cerebral cortex B.

    Exotoxin produces lethal effects

    179. Pt having Hypertension 210/120 and Creatinine 7, defect is in?  (Rabia Ali

    MCQ)

    A. JG apparatus | B. Mecula Densa

    180. Gastrectomy after 3 months anemia 

    A. microcytic hypochromic

    B. megaloblastic

    181. Drug contraindicated in impaired renal failure: 

    ` Gentamicin 

    182. Solubility of drug is increased by which factor

    A. increase lipid solubility

    183. Gastric secretions are inhibited by what.

    A. secretin 

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    B. Ach 

    184. In slow wave sleep what is unlikely.

    A. Inc muscle tone 

    B. Dreams unable to recall

    C. Delta waves

    185. Bradykinin ...

    A. kallikren 

    186. Alpha adrenergic stimulation causes

    A.. Vasodilation

    B. Lipolysis

    C. Pupillary dilation 

    187. GFR Clinically Measure by: 

    A. Creatinine

    B. Inulin

    C. PAH 

    188. Inappropriate regarding Azygous VeinPass through Esophageal Opening

    189. Rh Agglutinins

    A. present of RBC surface

    B. present in month of Rh -ve mother when give birth to rh +ve fetus

    190. Artery involved Anterior wall MI

    LAD artery

    191. Taste fibers through.

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    tractus solitarius

    192. After giving Glucocorticoids, there will be? (Asim’s MCQ) 

    Decrease Lymphocytes

    Decrease Neutrophil 

    193. Multiple long bone fracture...B.P 90/, Pulse 115. Initial management? 

    (Asim’s MCQ)

    A. Fracture stabilization

    B. Volume replacement

    C. Tracheostomy

    194. Atrial fibrillation

    A. Pulses deficit

    195. The process by which DNA is transferred from one bacterium to another

    by a virus is known as 

    A. TRANSDUCTION

    196. Fracture of Long Bones

    Fat Embolism

    197. Thirst is Reduced By? (Asim’s MCQ) 

    A. Angiotensin II 

    B. INC Volume of ECF 

    C. Stimulation of Hypothalamus

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