Medication safety problems, · Medication safety Avoiding adverse drug reactions Avoiding...

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Medication safety problems, solutions, challenges Professor Bryony Dean Franklin FFRPharmS CMSSQ Centre for Medication Safety & Service Quality

Transcript of Medication safety problems, · Medication safety Avoiding adverse drug reactions Avoiding...

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Medication safety – problems,

solutions, challenges

Professor Bryony Dean Franklin FFRPharmS

CMSSQ Centre for Medication Safety & Service Quality

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But...

4.3% of admissions are preventable drug-related admissions (Winterstein et al 2002)

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Medication safety

Avoiding adverse drug reactions

Avoiding medication errors

Optimising use by the patient

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1 • Understanding the problems

2 • Potential solutions

3 • Challenges

4 • What next?

Medication safety

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UNDERSTANDING THE

PROBLEMS

Part 1

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Understanding the problems –

quantitative studies

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Understanding the problems –

quantitative studies

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Understanding the problems -

analysis of NRLS data

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Understanding the problems

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Stage of drug use process

Actual patient outcome

Potential / potential patient outcomes

Causes and contributing factors

Medication errors

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Understanding the problems –

ethnographic observation

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Understanding the problems –

ethnographic observation

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Understanding the problems

Various theoretical frameworks for causes of

problems in healthcare:

• Accident causation model (Reason)

• London Protocol (Vincent et al)

• Yorkshire contributory factors framework (Lawton et al)

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Understanding the problems

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Understanding the problems

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Understanding the problems

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Task Factors

Individual Factors

Patient Factors

Team factors

Work Environment

Causes of

prescribing

errors

• System problems

• Practicalities

• Resources

• Physical and mental well-being

• Attitudes

• Education and training

• Complex patients

• Communication

• Multidisciplinary working

• Communication

• Over-reliance on defences

• Prescribing Team

• Time pressure

• Physical environment

• Workload

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Two views of safety

Medical view of safety

(avoidance of harm)

Patient view of

safety (“I feel safe”)

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POTENTIAL SOLUTIONS

Part 2

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Education

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Technology

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Evidence-based interventions

• Electronic prescribing /computerised decision

support?

• Barcode verification?

• IV pumps incorporating dose error reduction

software?

• Clinical pharmacists?

• Medication reconciliation?

• Educational interventions?

• Audit and feedback?

• Reducing interruptions?

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Patient safety strategies

• Strongly encouraged:

– “Do not use” list for hazardous abbreviations

• Encouraged:

– Clinical pharmacists

– Medication reconciliation

– Complementary methods to detect adverse events

– Computerised prescriber order entry (CPOE)

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CHALLENGES

Part 3

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Context

• What is relevant in one

context may not be

relevant in another

• IV antibiotics are likely to

be equally effective from

one hospital to another –

but the effectiveness of

smart pumps used to

administer them is likely

to vary considerably

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Context

• Strongly encouraged:

– “Do not use” list for hazardous abbreviations

• Encouraged:

– Clinical pharmacists

– Medication reconciliation

– Complementary methods to detect adverse events

– Computerised prescriber order entry

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Unintended consequences

• May be positive or negative

• Eg name stamps (positive)

• Eg for CPOE (negative)

– New error types

– Extra workload

– Workflow issues

– “Illusion of communication”

– Paper persistence

– “Never ending hardware

demands”

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Wide range of stakeholders

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Complexity

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Complexity

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Measurement

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Measurement

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Implementation fidelity

Reynolds M et al (2016). Improving feedback on junior doctors’ prescribing errors: mixed

methods evaluation of a quality improvement project. bmjqs-2015-004717

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WHAT NEXT?

Part 4

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What about our patients?

Patient involvement in their own safety

Patients guiding service development

Patients and the public involved in patient safety research

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1. Patient involvement in their own

safety

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Patient involvement in safety

• Patient involvement in safety increases

satisfaction and health outcomes, and reduces

avoidable harm (Weingart 2011)

• Medication safety in the inpatient setting

– Involvement in medication reconciliation?

– Self administration?

– Aware of current medication and encouraged to

prompt if potential errors identified?

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The IMPRESS study

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SAMQI project

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2. Patients guiding service development

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Focus group with junior doctors

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“…it’s OK to screw up once but there

ought to be a process that says you’ve

screwed up once and we’re going to

correct it so that it doesn’t happen

again. What’s unforgivable is if you’ve

got the ability to go on screwing up

time and time again”

Patient focus group participant

And what do the public think?

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3. Patients and the public involved in

patient safety research

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The IMPRESS study

Funded by The Health Foundation, an independent charity

working to continuously improve the quality of healthcare in the UK.

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Lay involvement in research

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Lay involvement in research

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Lay involvement in research

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Concluding thoughts

• Understand the local

problems

• Be aware of context

• Likely to need multi-

faceted solutions

• Look for and mitigate

unintended

consequences

• Involve patients and

carers