Medication among Children in Africa South of Sahara: Qualitative Systematic Review Professor Ebba...
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![Page 1: Medication among Children in Africa South of Sahara: Qualitative Systematic Review Professor Ebba Holme Hansen and Professor Susan R. Whyte ehh@farma.ku.dk.](https://reader036.fdocuments.us/reader036/viewer/2022062320/56649cf85503460f949c9ada/html5/thumbnails/1.jpg)
Medication among Children in Africa South of Sahara: Qualitative Systematic Review
Professor Ebba Holme Hansen and Professor Susan R. [email protected]
University of Copenhagen, Denmark
Copenhagen University’s Global Health Cluster temporary fund provided partial funding
![Page 2: Medication among Children in Africa South of Sahara: Qualitative Systematic Review Professor Ebba Holme Hansen and Professor Susan R. Whyte ehh@farma.ku.dk.](https://reader036.fdocuments.us/reader036/viewer/2022062320/56649cf85503460f949c9ada/html5/thumbnails/2.jpg)
Problem statement•The use of medicines is an important aspect of child health•Children are not just “small adults”•However, this topic has been sparsely dealt with in international research, not least in low-income societies.
Objective•To provide an overview of empirical evidence on children and medication in Africa south of Sahara
![Page 3: Medication among Children in Africa South of Sahara: Qualitative Systematic Review Professor Ebba Holme Hansen and Professor Susan R. Whyte ehh@farma.ku.dk.](https://reader036.fdocuments.us/reader036/viewer/2022062320/56649cf85503460f949c9ada/html5/thumbnails/3.jpg)
Systematic searches conducted without restrictions in•Medline•Embase•Psychinfo
Structured by using the same search terms in similar combinations in all databases
In all searches:
• “children”• “Africa, south of Sahara”• “Children” defined as 0-18 years• “Medicines” defined by 80 different search
terms
![Page 4: Medication among Children in Africa South of Sahara: Qualitative Systematic Review Professor Ebba Holme Hansen and Professor Susan R. Whyte ehh@farma.ku.dk.](https://reader036.fdocuments.us/reader036/viewer/2022062320/56649cf85503460f949c9ada/html5/thumbnails/4.jpg)
Flow chart of included/excluded studies
Duplicates 719
- Purely economic studies- Diagnostic tools- Drug abuse- Purely clinical studies- Studies where children
and adults are mixed
830 potentially relevant articles
1530 potentially relevant
references
132 included studies
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Data handling and extraction
Titles and abstracts assessed for eligibility
Full text papers
Extraction on data sheets
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Malaria
Diarrhoea
Fever
ARI
Epilepsy
Cough
Pneumonia
Asthma
Worms
Trachoma
Childhood illnesses general
Illnesses – in 132 studies
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Main points
•132 studies from 24 countries
•Most studies dealt with children under 5 years
In many studies age group was not specified
•Very few studies on prescribing and use
•Most studies recognised the multiple sources of treatment (popular, professional, folk sectors)
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Main points (contd.)
•Doses, dispensing, dosage forms barely mentioned
•Few studies on perceptions
•No reviews of the field of children and medicines in Africa
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Implications
• This study shows that medicine use in children is a neglected topic– except medication treatment of malaria/fever and diarrhoea in
small children
• As medicine use behaviours may track from childhood and adolescence into adulthood, knowledge about this topic also have implications for the improvement of medicine use in future adult populations
• The study indicates a lack of research interest in, particularly, older children as autonomous beings
• This little research only provides hints about proper interventions and policies to improve use of medicines among children
• Research to lay the foundation for future interventions should be high on the agenda
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Research gaps
• Studies on medicine use for chronic conditions and acute conditions other than malaria/fever and diarrhoea
• Characterisation of issues specific to children over 5
• The meaning and implications of (lack of) dosage forms for children
• Analyses of policies of relevance to children’s medicine use
• Children’s own experiences and the meaning of medicines in their daily lives.