Medical Device Market for Non-Invasive Cancer …...The global Cancer/Tumor Profiling market is...
13
Non-Invasive Cancer Treatment March, 2017. Medical Device Market for
Transcript of Medical Device Market for Non-Invasive Cancer …...The global Cancer/Tumor Profiling market is...
Non-Invasive Cancer Treatment
March 2017
Medical Device Market for
HISTOSONICS CONFIDENTIAL
CONTENTS
Introduction
Medical Devices Market -US
Medical Device Market Size
Medical Devices Market- Asia
Medical Devices Market for Cancer Treatment
Merger and Acquisition
Potential buyers
2
HISTOSONICS CONFIDENTIAL
INTRODUCTION
This research contains information for medical
devices market in general and for cancer
treatment There is data for biggest MampA
activity in this market and a list of companies
which showed interest in cancer treatment
3
HISTOSONICS CONFIDENTIAL
45
24
3
4
24USA
Western Europe
MiddleEast
Eastern Europe
Asia pacific
MEDICAL DEVICES
MARKET - US
The global medical devices market offers tremendousopportunity for US
bull Export competitiveness in overseas markets
bull Creating new and sustained export opportunities for US
4
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET SIZEThe largest medical device market in the world today is located in the UNITED STATES
5
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET - ASIA
bull In June 2015 IBA and Philips Healthcare agreed to provide proton therapy
systems to Indiarsquos Apollo Group at the Chennai hospital and Tata Memorial
Center
bull In September 2015 South Korearsquos National Cancer Center announced the
installment of IBArsquos pencil beam scanning (PBS) system
bull In December 2016 IBArsquos proton therapy system ProteusONE received
regulatory approval from Japanrsquos Pharmaceuticals and Medical Devices
Agency (PMDA
6
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
CONTENTS
Introduction
Medical Devices Market -US
Medical Device Market Size
Medical Devices Market- Asia
Medical Devices Market for Cancer Treatment
Merger and Acquisition
Potential buyers
2
HISTOSONICS CONFIDENTIAL
INTRODUCTION
This research contains information for medical
devices market in general and for cancer
treatment There is data for biggest MampA
activity in this market and a list of companies
which showed interest in cancer treatment
3
HISTOSONICS CONFIDENTIAL
45
24
3
4
24USA
Western Europe
MiddleEast
Eastern Europe
Asia pacific
MEDICAL DEVICES
MARKET - US
The global medical devices market offers tremendousopportunity for US
bull Export competitiveness in overseas markets
bull Creating new and sustained export opportunities for US
4
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET SIZEThe largest medical device market in the world today is located in the UNITED STATES
5
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET - ASIA
bull In June 2015 IBA and Philips Healthcare agreed to provide proton therapy
systems to Indiarsquos Apollo Group at the Chennai hospital and Tata Memorial
Center
bull In September 2015 South Korearsquos National Cancer Center announced the
installment of IBArsquos pencil beam scanning (PBS) system
bull In December 2016 IBArsquos proton therapy system ProteusONE received
regulatory approval from Japanrsquos Pharmaceuticals and Medical Devices
Agency (PMDA
6
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
INTRODUCTION
This research contains information for medical
devices market in general and for cancer
treatment There is data for biggest MampA
activity in this market and a list of companies
which showed interest in cancer treatment
3
HISTOSONICS CONFIDENTIAL
45
24
3
4
24USA
Western Europe
MiddleEast
Eastern Europe
Asia pacific
MEDICAL DEVICES
MARKET - US
The global medical devices market offers tremendousopportunity for US
bull Export competitiveness in overseas markets
bull Creating new and sustained export opportunities for US
4
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET SIZEThe largest medical device market in the world today is located in the UNITED STATES
5
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET - ASIA
bull In June 2015 IBA and Philips Healthcare agreed to provide proton therapy
systems to Indiarsquos Apollo Group at the Chennai hospital and Tata Memorial
Center
bull In September 2015 South Korearsquos National Cancer Center announced the
installment of IBArsquos pencil beam scanning (PBS) system
bull In December 2016 IBArsquos proton therapy system ProteusONE received
regulatory approval from Japanrsquos Pharmaceuticals and Medical Devices
Agency (PMDA
6
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
45
24
3
4
24USA
Western Europe
MiddleEast
Eastern Europe
Asia pacific
MEDICAL DEVICES
MARKET - US
The global medical devices market offers tremendousopportunity for US
bull Export competitiveness in overseas markets
bull Creating new and sustained export opportunities for US
4
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET SIZEThe largest medical device market in the world today is located in the UNITED STATES
5
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET - ASIA
bull In June 2015 IBA and Philips Healthcare agreed to provide proton therapy
systems to Indiarsquos Apollo Group at the Chennai hospital and Tata Memorial
Center
bull In September 2015 South Korearsquos National Cancer Center announced the
installment of IBArsquos pencil beam scanning (PBS) system
bull In December 2016 IBArsquos proton therapy system ProteusONE received
regulatory approval from Japanrsquos Pharmaceuticals and Medical Devices
Agency (PMDA
6
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET SIZEThe largest medical device market in the world today is located in the UNITED STATES
5
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET - ASIA
bull In June 2015 IBA and Philips Healthcare agreed to provide proton therapy
systems to Indiarsquos Apollo Group at the Chennai hospital and Tata Memorial
Center
bull In September 2015 South Korearsquos National Cancer Center announced the
installment of IBArsquos pencil beam scanning (PBS) system
bull In December 2016 IBArsquos proton therapy system ProteusONE received
regulatory approval from Japanrsquos Pharmaceuticals and Medical Devices
Agency (PMDA
6
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET - ASIA
bull In June 2015 IBA and Philips Healthcare agreed to provide proton therapy
systems to Indiarsquos Apollo Group at the Chennai hospital and Tata Memorial
Center
bull In September 2015 South Korearsquos National Cancer Center announced the
installment of IBArsquos pencil beam scanning (PBS) system
bull In December 2016 IBArsquos proton therapy system ProteusONE received
regulatory approval from Japanrsquos Pharmaceuticals and Medical Devices
Agency (PMDA
6
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
MEDICAL DEVICES
MARKET FOR CANCER
TREATMENT
CancerTumor Profiling Market worth 6187 Billion USD by 2021
httpwwwmarketsandmarketscomPressReleasescancer-tumor-profilingasp
7
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
The global CancerTumor Profiling market is poised to reach USD 6187 Billion by 2021 from
USD 2582 Billion in 2016 at a CAGR of 191 from 2016 to 2021
MAJOR FACTORS fueling market growth are
increasing number of cancer cases across the
globe the increasing utility of biomarkers
8
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
PAIN MANAGEMENT
DEVICES MARKET SIZE amp
FORECAST BY TYPE
The global pain management devices market was valued at USD 31855
million in 2014 and is expected to increase at a rate of 134 over the
forecast period
9
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
North America pain management devices market share by
type 2012 - 2022 (USD Million)
North America tumor ablation market share by technology
2015 - 2022 (USD Million)
The Global Radiation Therapy Equipment Market
The global Cancer therapy market is estimated to grow at 176 CAGR to reach $522billion by 2021 Breast cancer therapy is the
largestmarket expected to reach $308 billion by 2016 at an estimated CAGR of 15
00
5000
10000
15000
20000
25000
30000
35000
40000
45000
50000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Electrical Stimulators Radiofrequency Ablation
Analgesic Infusion Pump Neurostimulation Market
00
1000
2000
3000
4000
5000
6000
2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022
Radiofrequency Ablation
Microwave Ablation
North America
Europe
AsiaROW
xx
xx
xx
xx
0 1 2 3 4 5CA
GR
(2
01
6-2
01
1)
Rank (in terms of Market size)
Lung Cancer Surgery Market by Region 2016 (USD Billion)
10
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
Merger and Acquisition
The Largest Acquisitions of 2016 (So Far)
1 Canon Buying Toshibas Medtech Business for $6 Billion
2 BD Sells Respiratory Device Business for $250M
3 Dentsply Sirona Created Out of $145 Billion Deal
4 Abbott Wagers $58B to Acquire Alere
5 Stryker Paying Nearly $3 Billion on Hospital Products Maker
6 Strykerrsquos $128 Billion External Defibrillators Play
7 IBM Watson Pays $26B for Health Analytics Firm
8 TE Connectivity Spends $895M on Creganna
9 Smith amp Nephew Buys Surgical Robotics Firm for $275M
11
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
Potential buyers Johnson amp Johnson Completes Acquisition of Cougar Biotechnology
Royal Philips NV
Ethicon
Varian Medical Systems
Varian
Radiation therapy equipment
12
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
HISTOSONICS CONFIDENTIAL
Potential buyers
30700
8400
5520
4200
3400
2775
1730
1300
1280
1100
0 10000 20000 30000 40000
Abbott Laboratories (US)St Juda Medical (US)
Dentsply International (US) Sirona DentalSystems(US)
St Juda Medical (US) Thoratec (US)
Greatbatch (US) Lake Region Medical (US)
Stryker (US) Physio-Control(US)
Value In Million US Dollars
Acq
uir
ing
Co
mp
any
Targ
et C
om
pan
y
Greatbatch (US)Lake Region Medical
(US)-1730
0
10
20
30
40
50
60
70
80
90
100
Jul 2009- Jun 2011 Jul 2011- Jun2013 Jul 2013-Jun2015
Shar
e o
f To
tal D
eal V
alu
e
Other Private Equity Pharma Conglomerate Meditech
13
