Mechanistic transformation of Safrole to MDMA

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Transcript of Mechanistic transformation of Safrole to MDMA

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Themolecular [3,4-methylenedioxy- Serotonintransporters ... · role for MDMA,the concentration dependencefor MDMA stimulationofserotonineffiux(Fig. 1, dashedlines)is similar tothatforits

Themolecular [3,4-methylenedioxy- Serotonintransporters ... · role for MDMA,the concentration dependencefor MDMA stimulationofserotonineffiux(Fig. 1, dashedlines)is similar tothatforits

Using MDMA in Psychotherapy 1986

Using MDMA in Psychotherapy 1986

MDMA Synthese

MDMA Synthese

Illicit drug markets in Queensland...The MDMA market in Queensland Following an earlier contraction in the MDMA market between 2008 and 2011, the availability of MDMA in Queensland

Illicit drug markets in Queensland...The MDMA market in Queensland Following an earlier contraction in the MDMA market between 2008 and 2011, the availability of MDMA in Queensland

files.shroomery.orgfiles.shroomery.org/attachments/8257074-MDMA via reductive amination routes.pdfPMK PMK 14meth Reductive amination PMK / MDMA MDMA 9meth Scheme 8. 12meth). The origin

files.shroomery.orgfiles.shroomery.org/attachments/8257074-MDMA via reductive amination routes.pdfPMK PMK 14meth Reductive amination PMK / MDMA MDMA 9meth Scheme 8. 12meth). The origin

MDMA Common Precursor

MDMA Common Precursor

MDMA and PTSD

MDMA and PTSD

Psilocybin mdma - Amazon Simple Storage Service · Should psilocybin or MDMA become legal for medicinal use it will remain under these controlled conditions. MDMA EATS AWAY ... SHROOMS

Psilocybin mdma - Amazon Simple Storage Service · Should psilocybin or MDMA become legal for medicinal use it will remain under these controlled conditions. MDMA EATS AWAY ... SHROOMS

Ecstasy/MDMA Ecstasy/MDMA Overview MDMA = 3,4-methylene dioxy-N- methyl amphetamine (Schedule 1) Shares properties of amphetamines and hallucinogens.

Ecstasy/MDMA Ecstasy/MDMA Overview MDMA = 3,4-methylene dioxy-N- methyl amphetamine (Schedule 1) Shares properties of amphetamines and hallucinogens.

Non-linear Pharmacokinetics of MDMA (“Ecstasy”) and its Major … · 2008. 6. 30. · Non-linear MDMA pharmacokinetics occurred at plasma MDMA concentrations of 100 to 300 ng/ml

Non-linear Pharmacokinetics of MDMA (“Ecstasy”) and its Major … · 2008. 6. 30. · Non-linear MDMA pharmacokinetics occurred at plasma MDMA concentrations of 100 to 300 ng/ml

Future Drug Use and Drug Perspectives Denmark 2019...Safrole MDMA. PMMA. PMA and PMMA • Not typical stimulants • Slow onset of actions →overdose • Block monoamine oxidase inhibitor

Future Drug Use and Drug Perspectives Denmark 2019...Safrole MDMA. PMMA. PMA and PMMA • Not typical stimulants • Slow onset of actions →overdose • Block monoamine oxidase inhibitor

Identification of Safrole ; precursor chemicaldmsc2.dmsc.moph.go.th/.../km/illicit_test/IdentificationOfSafrole.pdf · Identification of Safrole ; a precursor chemical Tassaporn Khlaeo-om

Identification of Safrole ; precursor chemicaldmsc2.dmsc.moph.go.th/.../km/illicit_test/IdentificationOfSafrole.pdf · Identification of Safrole ; a precursor chemical Tassaporn Khlaeo-om

Andreas Leitner, Hildegard Lechner and Peter Kainz- Colour Tests for Precursor Chemicals of Amphetamine-Type Substances: Systematic study of colour tests for safrole and safrole-rich

Andreas Leitner, Hildegard Lechner and Peter Kainz- Colour Tests for Precursor Chemicals of Amphetamine-Type Substances: Systematic study of colour tests for safrole and safrole-rich

Mdma Presentation

Mdma Presentation

(+/-)-3,4-methylenedioxymethamphetamine (MDMA, …...It is a phenylisopopylamine derived from safrole, an aromatic oil found in sassafras, nutmeg, and other plants (Shulgin 1986).

(+/-)-3,4-methylenedioxymethamphetamine (MDMA, …...It is a phenylisopopylamine derived from safrole, an aromatic oil found in sassafras, nutmeg, and other plants (Shulgin 1986).

[MDMA]MDMA Neurochemistry

[MDMA]MDMA Neurochemistry

Speed Mdma 2009

Speed Mdma 2009

Methylenedioxymethamphetamine (MDMA, or “ecstasy ”) · Methylenedioxymethamphetamine (MDMA, or “ecstasy ”) ... certain substances in a condition known as ... is not lucid

Methylenedioxymethamphetamine (MDMA, or “ecstasy ”) · Methylenedioxymethamphetamine (MDMA, or “ecstasy ”) ... certain substances in a condition known as ... is not lucid

Cambodian Journal of Natural History - FFI ·  · 2018-04-24vation at the Royal University of Phnom Penh. ... MDMA is safrole oil, ... Phnom Penh Cambodian Journal of Natural History

Cambodian Journal of Natural History - FFI ·  · 2018-04-24vation at the Royal University of Phnom Penh. ... MDMA is safrole oil, ... Phnom Penh Cambodian Journal of Natural History

MDMA and Monoamines

MDMA and Monoamines