MCQ CNS PRACTICE TEST

8/6/2019 MCQ CNS PRACTICE TEST

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MCQ:

CNS PRACTICE TEST

Q.1.Dopaminergic transmission in brain isfacilitated by-----------

a.Levodopa c.Amantadine

b.Carbidopa d.Bromocriptine



Q.2.Mechanism of action of Entecapone is ------.

a.Inhibition of COMT

b.Inhibition of DOPA decarboxylase

c.Selective inhibition of MAO-B

d.Fascilitation of Dopamine synthesis



Q.4.Which anti-epileptic drug in therapeutic dose

causes least sedation?



a.Primidone c.Phenytoin

b.Clonazepam d.Phenobarbitone



Q.5.Antianxiety effect of Diazepam is due to------.

a.Stimulation of GABA-A receptor

b.Increased release of GABA

c.Inhibition of GABA-receptor

d.Stimulation of GABA-B receptor



Q.6.Tolerence develops to all the actions of

Levodopa EXCEPT--------.

a.Tachycardia c.Hypotensionb.Abnormal movements d.Vomiting



Q.7.Drug used in situational anxiety is ------.

a.Alprazolam c.Buspirone

b.Propranolol d.Flurazepam



Q.8.Drug of choice in Drug induced Parkinsonism

is ------.

a.Levodopa c.Ropinirole

b.Amantadine d.Benzhexol



Q.9.Drug of choice for Morphine withdrawal

syndrome is --------.

a.Methadone c.Naloxone

b.Buprenorphine d.Nalorphine



Q.10.Jaundice caused by Chlorpromazine is mainlydue to -------.

a.Hemolysis

b.Cholestasis

c.Hepatic cirrhosis

d.Impaired conjugation of bilirubin



Q.11.Analeptic drug preferred in treatment of

apnea of premature infant is ------.

a.Picrotoxin c.Camphor b.Doxapram d.Nikethamide



Q.12.Lithium toxicity can ideally be treated by-----.

a.Haemodialysis

b.Ion exchange

c.Forced alkaline diuresis

d.Exchange transfusion



Q.13.Longest acting Selective Serotonin Reuptake

Inhibitor is --------.

a.Fluvoxamine c.Paroxetineb.Fluoxetine d.Sertraline



Q.14.Which of the following drug is particularly

useful in anxiety associated with depression?



a.Diazepam c.Lorazepam

b.Oxazepam d.Alprazolam



Q.15.One of the following Antidepressant is

reported to increase rather than inhibit 5-HT

uptake.

a.Mianserine c.Venlafaxine

b.Tianeptine d.Trazodone



Q.16.The intramuscular dose of Morphine that can

induce serious respiratory depression in non-

tolerant person is -------.

a.10 mg c.40 mg

b.30 mg d.50 mg



Q.17.The measure of potency of inhalational

anaesthetic is -------.a.Blood:Gas partition coeffecient c.ED 50

b.Minimum alveolar concentration d.LD 50



Q.18.Which of the following is a gaseous

Inhalational anaesthetic?

a.Diethylether c.Halothane

b.Desflurane d.Nitrous oxide



Q.19.Drug used for absence seizure is -------.

a.Phenobarbitone c.Carbamazepine

b.Phenytoin d.Ethosuximide



Q.20.Which of the following antiepileptic is

GABA transaminase inhibitor?

a.Gabapentin c.Tiagabine

b.Vigabatrin d.Lamotrigine



Q.21.Phenytoin sodium is ineffective in following

type of epilepsy.

a.Simple partial c.Psychomotor



b.Absence d.Grandmal



Q.22.Antipsychotic drug having least severe

extrapyramidal side effect is -------.

a.Haloperidol c.Thioridazine

b.Risperidone d.Chlorpromazine



Q.23.Treatment of choice for bipolar manic

depressive illness is -------.

a.Flupenthixol c.Sodium valproate

b.Amytriptylline d.Lithium



Q.24.Mianserin acts by one of the followingmechanisms.

a.Inhibiting NA uptake

b.Inhibitiing 5-HT uptake

c.Inhibiting both NA & 5-HT uptake

d.Blocking presynaptic α 2 receptors



Q.25.Agranulocytopenia is major side effect of ------.

a.Clozapine c.Pimozide

b.Haloperidol d.Chlorpamazine



Q.26.The most common adverse effect of

Phenytoin is ------.

a.Hirsutism c.Skin rashes

b.Gum Hypertrophy d.Megaloblastic anaemia



Q.27.Carbamazepine is used in all of the following

epilepsies EXCEPT-------.

a.Grand mal epilepsy c.Trigeminal Neuralgia

b.Temporal lobe epilepsy d.Myoclonic seizure



Q.28.Alcohol withdrawl manifestations are best

controlled by --------.

a.Diazepam c.Flurazepam

b.Fluritrazepam d.Triazolam



Q.29.Which of the following is not an intravenousanaesthetic?

a.Ketamine c.Fentanyl-Droperidol

b.Thiopentone d.Sevoflurane



Q.30.Nitrous oxide is a ----------.

a.Slow acting general anaesthetic

b.Weak analgesic

c.Poor muscle relaxant

d.Long acting anaesthetic drug

MCQ CNS PRACTICE TEST

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