Master Drug List

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    Generic Name: Acetaminophen Trade Name: Tylenol

    Classification: Central analgesic/Non-narcoticanalgesic/antipyretic

    Action: Appears to inhibit prostaglandin synthesis in the CNS and , to a lesserextent, block pain impulses through peripheral action. Acts centrally on

    hypothalamic heat-regulating center, producing peripheral vasodilation (heat loss,

    skin erythema, diaphoresis).

    Adult Dosage: 325-650 mg q4-6h, max 4 g per day Reason Receiving: Pain relief

    Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationRare- hypersensitivityreaction

    Drug:Alcohol(chronicuse), liver enzymesinducers(e.g., cimetidine),hepatotoxic medications(e.g., phenytoin), warfarinFood: None Known

    Assess onset, duration, locationand intensity of pain. Assess forclinical improvement and reliefof pain, fever.

    Generic Name: acetaminophen and

    hydrocodone

    Trade Name: Vicodin

    Classification: Opioid agonist

    (schedule III)

    Action: Binds with opioid receptors; also antipyretic

    Adult Dosage: 500 mg/5 mg one to twotablets q.4-6h as needed for pain

    Reason Receiving: moderate to moderately severe pain

    Newborn Dosage: Safety andeffectiveness has not been established

    Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Lightheadedness/dizziness

    Sedation

    Nausea and vomiting

    Constipation

    Respiratory depression

    Skin rash and pruritus

    Give without regard to meals.

    Tablets may be crushed.

    Obtain VS before giving

    medication; respirations 12 or

    less (20 or less in kids) hold

    medication and call physician.

    Assess onset, type, location,

    duration of pain.

    Evaluate for urinary retention.

    Monitor daily bowel pattern

    and stool consistency.

    Start deep breathing and

    coughing exercises.

    Assess for clinical

    improvement; record onset of

    relief of pain, cough.

    Caution with breastfeeding

    mothers

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    Generic Name: acetaminophen 500mg and oxycodone 5 mg

    Trade Name: Tylox

    Classification: opioid analgesic; non-narcotic analgesic, antipyretic

    Action: semisynthetic narcotic analgesia involving the CNS, andblocks pain impulses; also, results in antipyresis

    Adult Dosage: one capsule q6h asneeded for pain

    Reason Receiving: moderate to moderately severe pain orantiemesis

    Newborn Dosage: safety andeffectiveness has not been established Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Dizziness/lightheadedness

    Sedation

    Nausea, vomiting

    Skin rash and pruritus

    Constipation

    May be habit forming

    Caution if breasting feeding

    mother

    Assess onset, type, location and

    duration of pain.

    Assess for clinical improvement

    and relief of pain/fever.

    Assess mental and/or physical

    abilities

    Generic Name: Acetylsalicylic Acid Trade Name: AspirinClassification: Nonsteroidal salicylate/Anti-inflammatory

    Action: Inhibits prostaglandin synthesis, acts on the hypothalamus heat-regulating center,interfers with production of thromboxane A, a substance that

    stimulates platelet aggregation.

    Adult Dosage: 80-325mg/day Reason Receiving: Reduces inflammation due to osteoarthritis

    Geriatric Dosage: Same as above Pregnancy Category: C (D if full dose used in 3 rd trimester ofpregnancy)

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    GI distress(includingabdominal distention,cramping, heartburn, mildnausea); allergic reaction(including bronchospasm,

    pruritis, urticaria)

    Drug: ETOH, NSAIDs,Antiacids, urinary alkalinizers,Anitcoagulants, heparin,thrombolytics, Plateletaggregation inhibitors, valproicacid, methotrexate, zidovudine,

    ototoxic meds, vancomysin,probenecid, sulfinpyrazone.Food: None Known

    Assess type, location, durationof pain, inflammation Monitorurinary pH Assess skin forecchymosisReport tinnitus or persistent

    abdominal GI pain

    Generic Name: Acyclovir Trade Name: Zovirax

    Classification:Synthetic Nucleoside/Antiviral Action: Converts to acyclovir triphosphate, becoming part of DNAchain.

    Adult Dosage: 200mg Q4H, 5 times per day Reason Receiving: Prevent infection

    Newborn Dosage: N/A Pregnancy Category: B

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationRare; vomiting, diarrhea, rash, HA History of allergies

    Assess herpes simplex lesions bftreatment to assess therapeutic effect

    Provide comfort measures

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    Generic Name: Albuterol Trade Name: Albuterol Sulfate

    Classification: Sympathomimetic/Bronchodilator Action: Stimulates beta-adrenergic receptors in lungs, resulting inrelaxation of bronchial smooth muscle.

    Adult Dosage:2.5mg 3-4 times/day over 5-15 mins Reason Receiving: Relief of bronchospasm

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    HA, nausea,restlessness,nervousness, tremors,dizziness, throat drynessand irritation, pharyngitis,B/P changes, heartburn,transient wheezing.

    Drug: Beta-blockers,digoxin, MAOIs, tricyclicantidepressants, Thyroidhormone.Food: None Known

    Monitor rate, depth, rhythm,type of respirations and pulse.Assess lung sounds.Increasefluids. Rinse mouth with waterafter inhalation.

    Generic Name: Allopurinol Trade Name: Zyloprim

    Classification: Antigout/Xanthine oxidase inhibitor Action: Decreases uric acid production by inhibiting xanthineoxidase, an enzyme

    Adult Dosage:600-800mg/day Reason Receiving: Decrease uric acid due tochemotherapy

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Somnolence; Unusual hair loss;diarrhea; HA

    Tell patient to drink 10 to 12 glasses ofwater daily. Monitor I&O, assess cbc,uric acid hepatic function tests Assessurine for color, clarity, odor, assess fortherapeutic response

    Generic Name: Alprazolam Trade Name: Xanax

    Classification: benzodiazepine(schedule IV)/Antianxiety Action: Enhances the action of the neurotransmitter gamma-aminobutyric acid(GABA) in the brain

    Adult Dosage: 0.25-0.5mg 3 times per day Reason Receiving: Treatment for Anxiety

    Geriatric Dosage: 0.25mg 2-3 times a day Pregnancy Category: DSide Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationAtaxia, light headedness,mild somnolence, slurredspeech, confusion,constipation

    Drug: Potentiated effectswhen used with other CNSdepressants (including alcohol).Ketoconazole, nefazodone,fluvoxamine may inhibit hepaticmetabolism, increase serum

    concentration. Food: Noneknown

    Offer emotional support assessmotor responses, performhepatic/renal function test, bloodcounts periodically. Evaluate fortherapeutic response

    Generic Name: Amitriptyline HCL Trade Name: Elavil

    Classification:Antineuralgia/Antidepressant Action: Blocks reuptake of neurotransmitters, at presynaptic membranes,increase availability of receptor sites.

    Adult Dosage: 25-100mg at bedtime Reason Receiving: Relief of neuropathic pain

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Dizziness, somnolence,dry mouth, orthostatichypotension, HA,increased appetite,weight gain, nausea,fatigue, unpleasant taste

    Drug: CNS depressants,Antithyroid agents,Phenothiazine,Cimetidine, valporic acid,clonidine,sympathomimetics.Food: None Known

    Assess location, type,frequency, duration of pain.Monitor B/P & Pulse. Assesspain relief.

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    Generic Name: Amlodipiine Besylate Trade Name:Norvasc

    Classification: Calcium Channel Blocker/Antihypertensive Action: Inhibits Ca movement across cardiac and vascularsmooth muscle cell membranes.

    Adult Dosage: Initially 5mg/day as a single dose. Increase by2.5mg/day for 7-14 days

    Reason Receiving: Hypertension

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Peripheral edema, HA, flushing,dizziness, palpitations, nausea,unusual fatigue or weakness

    Assess b/p, apical pulseAssess for peripheral edema.Assess skin for flushing.

    Generic Name: Amphotericin B Lipid Trade Name: Abelcet

    Classification:Antifungal/Antiprotozoal Action:Generally fungistatic but may become fungicidal with highdosages or very susceptible microorganisms. Binds to stero;s om fungal

    cell membrane.Adult Dosage: 2.5-5mg/kg/day at a rate of2.5mg/kg/hr

    Reason Receiving: Prevents fungal infection

    Newborn Dosage: N/A Pregnancy Category:B

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Chills, fever, increased serumcreatinine, multiple organ failure

    Hx fo allergies to amphotericin B,sulfite. Monitor b/p, temp, pulse,resp. Evaluate IV site forphlebitis(heat, pain, red streakingover vein). Monitor I&O.

    Generic Name: Aripiprazole Trade Name: Abilify

    Classification: Dopamine agonist/Antipsychoiticagent

    Action: Provides partial agonist activity at dopamine andserotonin (5-HT1A) receptors and antagonist activity at serotonin (5-HT2A) receptors.

    Adult Dosage: 2-5mg/day Reason Receiving: Depression

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Weight gain, HA, insomnia,vomiting

    Periodically monitor weight. Monitor forextrapyramidal symptoms (abnormalmovement), tardive dyskinesia(protrudingtongue, puffing of cheeks,chewing/puckering of mouth). Monitor B/P,pulse. Assess for therapeutic response.

    Generic Name: Ascorbic Acid Trade Name: Vitamin C

    Classification: Vitamin Action: assist in tissue repair, involved in oxidation reaction

    Adult Dosage: 50-200 mg per day Reason Receiving: supplement

    Newborn Dosage: na Pregnancy Category: A

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationAbdominal cramps, NV, diarrhea,increased urination.

    Monitor for Abdominal cramps, NV,diarrhea, increased urination.

    No complaints of abdominal cramp,NV.

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    Generic Name: aspirin Trade Name: Ecotrin

    Classification: nonsteroidal salicylate Action: inhibits prostaglandin synthesis, acts on thehypothalamus regulating center and inhibits plateletaggregation

    Adult Dosage: 325-650 mg Reason Receiving: prophylactic for MI

    Geriatric Dosage: same Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationGI distressAllergic reaction

    Alcohol, NSAIDs,antacids, heparin, plateletaggregation inhibitors,valproic acid

    Assess skin for ecchymosisAssess pain levelAssess PLT

    Generic Name: Atenolol Trade Name: Tenormin

    Classification: Beta-AdrenergicBlocker/Antihypertensive

    Action: Blocks beta1-adrenergice receptors in cardiactissue.

    Adult Dosage: 25-50mg daily Reason Receiving: hypertension

    Newborn Dosage: N/A Pregnancy Category: D

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Hypotension manifested as coldextremities, constipation ordiarrhea, diaphoresis, dizziness,fatigue, HA, nausea

    Assess B/P, apical pulse beforeadmin med. Respiration fordifficulty in breathing. Monitor I&O.Monitor bowel activity. Assessextremities for coldness.

    Generic Name: atorvastatin calcium Trade Name: LipitorClassification: HMG-CoA reductaseinhibitor; antihyperlipidemic

    Action: inhibits the enzyme that catalyzes the early step in cholesterolsynthesis; decreased LDL and VLDL, and increases HDL

    Adult Dosage: 10-20 mg (80 max) Reason Receiving:Newborn Dosage: Safety not established Pregnancy Category: X

    Side Effects Nursing Implications R/T Adm. & S. E EvaluationGenerally well tolerated; if any, mildand transient.HeadacheMyalgia, rash, pruritis, allergy

    Monitor for headacheAssess for rash, pruritus, malaiseMonitor cholesterol, triglyceride labs fortherapeutic response

    Generic Name: azithromycin Trade Name: Zithromax

    Classification: macrolide; antibiotic Action: binds to ribosomal receptor sites of susceptible organisms, inhibitingRNA-dependent protein synthesis; bacterostatic/bactericidal

    Adult Dosage: 1200 mg once weekly Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: B

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Nausea, vomiting, diarrhea, abdominalpain Check for GI discomfort, nausea,vomitingMonitor daily pattern of bowels and stoolconsistencyMonitor hepatic function tests, assess forhepatotoxicity (malaise, fever, abdominalpain, GI disturbancesBe alert for superinfection (fever,vomiting, diarrhea, anal/genital pruritus,oral mucosal changes

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    Generic Name: Baclofen Trade Name: Lioresal

    Classification: skeletal muscle relaxant, antispastic Action: inhibits transmission of reflexes at spinal cord level

    Adult Dosage: 40-80mg/day Reason Receiving: spasms due to spinal injury

    Newborn Dosage: na Pregnancy Category:C

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationTransient somnolence, asthenia, dizziness,light headedness, NV. Hypotension,confusion,

    Assess for paradoxical reaction. For longterm therapy, hepatic/renal function test,Evaluate for therapeutic response.

    K-3.6NA- 141CL- 105BP 151/84-132-78No pt complains of somnolence,dizziness, lightheadedness, nausea

    Generic Name: betamethasone Trade Name: Diprolene

    Classification: adrenocorticosteroid;anti-inflammatory, immunosuppressant

    Action: controls rate of protein synthesis, prevents or controlsinflammation; decreases tissue response to inflammatory process

    Adult Dosage: 0.6-7.2 mg/day po Reason Receiving:Newborn Dosage: 0.0175-0.25mg/kg/day in 3-4 divided doses po

    Pregnancy Category: C (D if in first trimester)

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Increased appetite

    Abdominal distention

    Nervousness

    Insomnia

    False sense of well being

    Topical: burning, stinging,pruritus

    Question for hypersensitivity toany of the corticosteroids

    Obtain baselines for height,weight, BP, glucose, electrolytes

    Monitor BP, blood glucose,electrolytes

    Apply topical preparationsparingly and not on broken skinor areas of infection

    Do not apply to wet skin, face oringuinal areas

    IM inject slowly, deep IM intolarge muscle

    Generic Name: bisacodyl Trade Name: Dulcolax

    Classification: GI stimulant Action: stimulates intramural nerve plexi of colonic smooth muscle

    Adult Dosage: 10 mg rectally Reason Receiving: induce bowel movement

    Geriatric Dosage: same Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationSome degree of abdominaldiscomfort

    NauseaMild crampsFaintness

    With rectal, mild burning ofrectal mucosa

    AntacidsCimetidine

    FamotidineRanitidineMilk

    Chill for 30 min in frig if too softMoisten suppository with cold

    water before insertionEncourage adequate fluidintakeAssess BS for peristalsisMonitor bowel activity and stoolconsistencyMonitor electrolytes

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    Generic Name: budesonide Trade Name: Symbicort/FormoterolClassification: anti-inflammatory, antiallergy Action: relieves symptoms of allergic rhinitisAdult Dosage: 1 spray each nostril per day Reason Receiving:

    Newborn Dosage: nebulizer 0.5 mg/day Pregnancy Category: B

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Flu-like symptoms, headache,pharyngitisBack pain, vomiting, altered taste,voice changes, abdominal pain,nausea, dyspepsia

    Monitor relief of symptoms

    Generic Name:Bupropion HCL Trade Name:Wellbutrin XL

    Classification:Aminoketone/Antidepressant Action: Blocks reuptakeof neurotransmitters,(serotonin,norepinephrine) at CNS presynaptic membranes, increasing availability

    at postsynapticeceptor sites.Reduces firing rate of noradrenergic

    neurons.Adult Dosage:150mg daily Reason Receiving: Major depression

    Newborn Dosage: N/A Pregnancy Category:B

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Constipation, weight gain or loss,nausea, vomiting, anorexia, drymouth, HA, diaphoresis, tremor,sedation, insomnia, dizziness,agitation.

    Hepatic/renal function tests.Assess appearance, behavior,speech pattern, level of interest,mood.

    Generic Name: busPIRone Trade Name: BuSparClassification: nonbarbiturate Action: binds to serotonin, dopamine at presynaptic neurotransmitter

    receptors in CNS; anxiolytic

    Adult Dosage: 5 mg 2-3 times a day Reason Receiving: augment depression meds

    Geriatric Dosage: 5 mg bid Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Dizziness, somnolence,nausea, headacheNervousness, fatigue,insomnia, dry mouth,lightheadedness, moodswings, blurred vision,poor concentration,diarrhea, paresthesia

    Alcohol, other CNSdepressantsErythromycin, MAOIsSt. Johns wortGrapefruit and grapefruitjuice

    Offer emotional support ifanxiousAssess motor responses(agitation, trembling, tension),autonomic responses (cold,clammy hands; diaphoresis)Monitor LFTs, renal function,blood counts for long-term useAssist with ambulation if dizzy

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    Generic Name: Calcium Carbonate- Vit D Trade Name:Alpo-Cal, Caltrate

    Classification: electrolyte replenisher Action:Assists in regulating release/storage of hormones.Neutralizes/reduces gastric acid(increases ph)

    Adult Dosage: 1-2 g a day in divided doses Reason Receiving: prevention of calcium deficiency

    Newborn Dosage: na Pregnancy Category: na

    Side Effects

    Nursing Implications R/T

    Administration & Side Effects EvaluationMilk alkali syndrome(HA,decreased appetite, NV, unusualfatigue) Chalky taste

    Assess BP, EKG, and cardiacrhythm renal function, serummagnesium phosphate, potassiumconcentrations.

    Generic Name: Calcium Polycarbophil Trade Name: Fiber-Lax

    Classification: Bulk-forming laxative/antidiarrheal Action: Retains water in intestines, opposesdehydrating forces of bowel.

    Adult Dosage: 2 tab- 625 mg orally Reason Receiving: Prevents Constipation

    Newborn Dosage: N/A Pregnancy Category: C

    Side Effects

    Nursing Implications R/T

    Administration & Side Effects EvaluationAbdominal pain, Nausea, vomiting Take with adequate amount of

    water(8 ounces)

    Generic Name: carbamazepine Trade Name: Tegretol

    Classification: iminostilbene derivative;anticonvulsant, antipsychotic

    Action: decreases sodium, calcium ion influx into neural membranes,reducing post-tetanic potentiation at synapses; anticonvulant effect

    Adult Dosage: 200 mg bid Reason Receiving: withdrawal

    Geriatric Dosage: 100 mg 1-2 times a day Pregnancy Category: D

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Drowsiness, dizziness,nausea, vomiting

    Visual abnormalities(spots, difficult focusing,blurred), drymouth/pharynx, tongueirritation, headache, fluidretention, diaphoresis,constipation, diarrhea

    Anticoagulants,clarithromycin, diltiazem,

    erythromycin, estrogens,propoxyphene,quinindine, steroidsAntipsychotics,haloperidol, tricyclicsOther anticonvulsants,barbiturates,benzodiazepine, valproicacid, MAOIsSt. Johns wort,grapefruit, grapefruit juice

    Monitor CBC, iron, UA, BUNAssess for early signs of toxicity

    (fever, sore throat, mouthulcerations, unusualbruising/bleeding, joint pain)

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    Generic Name: carvedilol Trade Name: CoregClassification: beta-adrenergic blocker;antihypertensive

    Action: has nonselective beta-blocking and alpha-adrenergic blocking activity;causes vasodilation; reduces cardiac output and tachycardia; reduces peripheralvascular resistance

    Adult Dosage: 6.25 mg/day (50 max) Reason Receiving: HypertensionNewborn Dosage: safety not established Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Generally well tolerated with mildtransient side effectsFatigue, dizzinessDiarrhea, bradycardia, rhinitis, backpain

    Monitor BP for hypotension and resp fordyspneaAssess pulse for quality, irregular rate,bradycardiaMonitor EKG for arrhythmiasAssist with ambulation if dizzinessoccursAssess for CHF (dyspnea, night cough,peripheral edema, distended neck veins)Monitor I&O

    Generic Name: cefazolin Trade Name: cefazolin

    Classification: first-gen cephalosporin Action: Inhibits cell wall synthesis of bacterial cell

    membranes; bactericidalAdult Dosage: 0.5-1 g q.6-8 h postop Reason Receiving: Prophylaxis postoperatively

    Geriatric Dosage: same Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Oral candidiasisMild diarrheaMild abdo crampingVaginal candidiasisNausea

    AminoglycosidesFurosemideProbenecidWarfarin = bleedingNo herbs or food

    Assess oral cavityMonitor daily bowel activity andstool consistencyMonitor I&O, renal functiontestsBe alert for superinfection(fever, vomiting, diarrhea)

    Generic Name: Cefepime HCL/ Trade Name: Maxipime

    Classification: 4 generation cephalosporin Action: binds to bacterial cell membranesAdult Dosage:1-2 grams q12h over 7-10days Reason Receiving: pneumonia

    Newborn Dosage: Pregnancy Category:B

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Oral candidiasis, mild diarrhea, mildabdominal cramping

    Question for allergies tocephalosporins and penicillins

    Assess oral cavity for white patches.Monitor bowel activity, I&O, renalfunction test

    Generic Name: Ceftriaxone Trade Name: RocephinClassification: 3

    rgeneration

    cephalosporin/AntibioticAction: Binds to bacterial cell membranes, inhibits cell wallsynthesis. Bactericide.

    Adult Dosage: 1-2g as a single dose or in 2 divideddoses

    Reason Receiving: Treatment of gram(-) infections

    Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Oral candidiasis, milddiarrhea, mild abdominal

    Drug: ProbenecidFood: None Known

    Assess hx of sensitivity. Assessoral cavity. Monitor bowel

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    cramping, vaginalcandidiasis

    pattern and activity. Asses forsuperinfection: fever, vomiting,diarrhea, anal/genital pruritis,oral mucosal changes.

    Generic Name: Cetirizine HCl Trade Name: ZyrtecClassification: 2nd Generation Piperazine/Antihistamine Action: Competes with histamine for H1-receptor sites on

    effector cells in GI tract, blood vessels, respiratory tract.Adult Dosage: Initially 5-10mg/day as a single or in 2 divideddoses

    Reason Receiving: Seasonal Allergies

    Newborn Dosage: N/A Pregnancy Category: B

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Pharyngitis; dry mucousmembranes, nose, throat; N/V;abdominal pain; HA; dizziness;fatigue; thickening of mucus;somnolence; photosensitivity;urinary retention

    Assess lung sounds. Increasefluids to maintain thin secretionsand offset thrist. Monitorsymptoms for therapeuticresponse.

    Generic Name: Chemo-Cytarabine Trade Name: Cytarabine

    Classification:Antimetabolite/Antineoplastic Action: Converted intracellularly to nucleotide. Cell cycle-specificfor S phase of cell division.

    Adult Dosage: 75-200mg/m2/day for 5-10 days Reason Receiving: Prevents cell growth

    Newborn Dosage: N/A Pregnancy Category: D

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Asthenia, fever, pain, alteredtaste/smell, nausea, vomiting

    Monitor CBC for evidence ofmyelosuppression.Monitor for blood dyscrasias(fever,sore throat, signs of local infection,unusual bruising/bleeding).Increase fluid intake

    Generic Name: Chemo-cyclophosphamide(sye-cloe-FOSS-fa-mide

    Trade Name: Cytoxam

    Classification: alkylating agent Action: Inhibits DNA,RNA protein synthesis

    Adult Dosage:400-1800mg/m2 per treatment course (1-5days)

    Reason Receiving: ACL

    Newborn Dosage: na Pregnancy Category: na

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Marked leucopenia 8-15 days afterinitial therapy. Nausea vomiting

    Obtain WBC count weekly duringtherapy or until maintenance dose isestablished than at 2-3 wk intervals.Monitor CBC, Monitor for hematologictoxicity.

    No complaints of NVWBC-4.0L RBC- 2.78LPLT- 152L Seg. Neu-2.6Lymph-0.5L Mono-0.8Baso- 0.0 EOSN-0.0

    Generic Name: Chemo- Decitabine DACOG Trade Name:

    Classification: antineoplastic Action: exerts cytotoxic effect on rapidly dividing cells

    Adult Dosage: 15 mg given over 3hrs q8h Reason Receiving: treatment of AML

    Newborn Dosage: Pregnancy Category: D

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationFever, nausea, cough, constipation, Monitor for fever, sore throat, signs of Did not administer. No c/o of NV,

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    diarrhea, peripheral edema,echhymosis, arthralgia.

    local infection. Monitor and report N/V,diarrhea, If pt has active oruncontrolled infection, treatment shouldbe stopped and not restarted untiltoxicity if resolved.

    diarrhea, peripheral edema,echymosis, arthralgia.Pt being treated for pneumonia.Temp-96.5Pt c/o unproductive cough

    Generic Name: Chemo-etoposide (eh-TOE-poe-side) Trade Name: Toposar, VePesid

    Classification: Epipodophyllotoxin Action: Inhibits single and double stranded breaks in DNA.Adult Dosage: 150 mg/m2/day for 2-3 days, 2-3 cycles Reason Receiving: ACL

    Newborn Dosage: na Pregnancy Category: na

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Mild to moderate nausea/vomiting,alopecia.

    Obtain hematologic test beforeadministration at frequent intervalsduring therapy. Use anti-emetics tocontrol nausea and vomiting.

    No complaints of NVHGB-9.9L HCT-25.9LWBC- RBC-PLT- Seg. Neu-2.6Lymph-0.5L Mono-0.8Baso- 0.0 EOSN-0.0

    Generic Name: Chemo-Midostaurin Trade Name:Chemo-Midostaurin

    Classification: Kinases inhibitor Action: blocks a key class of enzymes kinases that often spur cancercell growth. It works by targeting the FLT3 cell receptor, which is

    overactive in the white blood cells

    Adult Dosage: Reason Receiving: reduces the number of circulatingleukemia cells

    Newborn Dosage: Pregnancy Category:

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Generic Name: cholecalciferol Trade Name: Vitamin D3Classification: Fat-soluble vitamin/NutritionalSupplement

    Action: Stimulates calcium/phosphate absorption from smallintestine, promotes secretion of calcium from bone to blood,promotes reabsorption of phosphate in renal tubules; acts on bonecells to stimulate skeletal growth and on parathyroid gland tosuppress hormone synthesis and secretion

    Adult Dosage: 400 units per day Reason Receiving: Vitamin deficiency

    Newborn Dosage: Pregnancy Category:A(C if used in doses above RDA)

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    None Known Begin therapy at lowest possibledosage. Encourage adequate fluidintake. Monitor Ca+, P+, Mg+, BUNlevels

    Generic Name: Ciprofloxacin HCl Trade Name: Cipro

    Classification: Fluoroquinolone/Anti-infective Action: Inhibits enzyme, DNA gyrase, in susceptible bacteria,interfering with bacterial cell replication.

    Adult Dosage: 500-750 mg q8-12h Reason Receiving: Prevent infection

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationNausea, diarrhea, dyspepsia, Question for history of sensitivity to

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    Vomiting, constipation, flatulenceConfusion, crystalluria, abdominalpain

    Ciprofloxacin, quinolones. Eval for foodtolerance, bowel activity, dizziness,HA, visual changes, chest, joint pain

    Generic Name: citalopramhydrobromide

    Trade Name: Celexa

    Classification: antidepressant(serotonin inhibitor)

    Action: relieves depression

    Adult Dosage: 20 mg Reason Receiving: Depression

    Newborn Dosage: not indicated Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S.E. Evaluation

    Nausea, dry mouth, somnolence,insomnia, diaphoresis.Tremor, diarrhea, fatigue, anxiety,vomiting, anorexia

    Observe, record behaviorAssess psychological status, thoughtcontent, sleep pattern, appearance,interest in environment, mood

    Generic Name: Clindamycin Trade Name: Cleocin

    Classification: Lincosamide/Antibiotic Action: Inhibits protein synthesis of bacterial cell wall by binding to bacterialribosomal receptor sites. Topically, decrease fatty acid concentration on skin.

    Adult Dosage: 1.2-1.8g/day in 2-4 divided doses Reason Receiving: Treatment of infection

    Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Abdominal pain, nausea,vomiting, diarrhea Drug:Adsorbentantidiarrheals,Erythromycin,Neuromuscular blockers.Food: None Known

    Monitor bowel activity/pattern.Assess hx of sensitivity. Monitorfor superinfection: fever,vomiting, diarrhea, anal/genitalpruritis, oral mucosalchanges(ulceration, pain,erythema)

    Generic Name: Clopidogrel Trade Name: Plavix

    Classification: Thienopyridine derivative/Antiplatelet Action: Inhibits binding of enzyme adenosine phosphate (ADP) to itsplatelet receptor and subsequent ADP-mediated activation of a glycoproteincomplex.

    Adult Dosage: 300mg loading dose then 75mg/day Reason Receiving: Graft patency(Saphenous vein)Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Skin disorders, URI,chest pain, flu-likesymptoms, HA, dizziness,arthralgia

    Drug:Aspirin, NSAIDs,Fluvastatin, phenytoin,tamoxifen, tolbutamide,torsemide, warfarin.Food: None Known

    Monitor platelet count. AssessBUN, creat, bilirubin, AST, ALT,WBC, Hgb

    Generic Name: Clonidine HCL Trade Name: Clonidine

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    Classification: Antiadrenergic, sympatholytic/Antihypertensive Action: Prevents pain signal transmission to brain and produce analgesiaat pre- and post-alpha-adrenergic receptors in spinal cord

    Adult Dosage: 0.1mg twice/day Reason Receiving: HTN

    Geriatric Dosage: 0.1mg at bedtime Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Dry mouth, somnolence,dizziness, sedation,constipation

    Drug: beta-blocker,Tricyclic antidepressants.Food: None Known

    Obtain B/P before admin.Monitor bowel activity. Sideeffects diminish with therapy.

    Generic Name: Clonozepam Trade Name: Klonopin

    Classification: benzodiazepine (ScheII)/anticonvulsant

    Action: Depresses all levels of CNS; depresses nerve impulsetransmission in motor cortex. Suppresses abnormal discharge inpetit mal seizures.

    Adult Dosage:1.5mg/day in 3 divided doses Reason Receiving: Bipolar Disorder

    Newborn Dosage: N/A Pregnancy Category: D

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Mild, transient drowsiness; ataxia;

    behavior disturbances(aggression,irritability, agitation)

    Hx of seizure disorder.Implement

    safety measures. Performrenal/hepatic function test.Evaluate for therapeutic response.

    Generic Name: Clotrimazole Cream Trade Name: Lotrimin

    Classification:Antifungal Action: binds with phospholipids in fungal cell membrane.

    Adult Dosage: 1% Reason Receiving: treat fungal infection

    Geriatric Dosage: apply twice a day up to 8weeks Pregnancy Category:C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Pruritis, burning, stinging,

    erythema, urticaria

    Drug: None Known

    Food: None Known

    Check skin for erythema,

    urticaria, blistering, pruritis,stinging, burning

    Generic Name: Colchicine Trade Name: Colchicine

    Classification:Alkaloid/Antigout Action: Decrease leukocyte motility, phagocytosis, lactic acid production

    Adult Dosage: 0.6-1.2mg up to 6mg Reason Receiving: Gouty Arthritis

    Geriatric Dosage: Same as above Pregnancy Category: D(parental)/C(oral)

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationN/V, abdominaldiscomfort

    Drug: Bone marrowdepressants,clarithromycin,erythromycin, NSAIDs.Food: None Known

    Increase fluid intake. MonitorI&O. Assess therapeutic relief.

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    Generic Name: collagenose top oint Trade Name: Santyl

    Classification: enzumatic debriding agent Action: debrides dead skin

    Adult Dosage: small amount applied daily Reason Receiving: treatment of pressure ulcer

    Newborn Dosage: Pregnancy Category:

    Side Effects

    Nursing Implications R/T

    Administration & Side Effects EvaluationAdverse reactions, burning sensation,erythema,

    Contradictions- patients who haveshown local or systemic hypersentivityto collogenose. Avoid products withsilver or mercury.

    No complains of pain or erythemaobserved

    Generic Name: conjugated estrogen Trade Name: Premarin

    Classification: estrogen; hormone Action: increases synthesis of DNA, RNA, various proteins in target tissues;reduces release of gonadotropin-releasing hormone (FSH) and LH release;promotes normal growth, development of female sex organs, prevents bone loss

    Adult Dosage: 0.3-0.625 mg/day Reason Receiving:

    Newborn Dosage: not indicated Pregnancy Category: X

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Vaginal bleeding; breast

    pain/tenderness, gynecomastiaHeadache, hypertension, intoleranceto contact lenses

    Assess BP periodically

    Check for edema, weigh dailyReport S/S of thromboembolic disorders(sudden severe headache, SOB,vision/speech disturbance,weakness/numbness of extremity, loss ofcoordination, pain in chest, groin or leg)

    Generic Name: Cyclobenzaprine Trade Name: Flexeril

    Classification: skeletal muscle relaxant Action: reduces tonic somatic muscle activity at thebrainstem.

    Adult Dosage: Initially 5 mg 3 times per day Reason Receiving: muscle spasms- fibromyalgia

    Newborn Dosage: na Pregnancy Category: na

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Somnolence, dry mouth, dizziness Record onset, type, location,duration of muscular spasm. Checkfor immobility, stiffness, swelling.Assess for therapeutic response.

    Generic Name: cyclophosphamide Trade Name: CytoxanClassification: alkylating agent;antineoplastic

    Action: inhibits DNA, RNA protein synthesis; prevent cell growth, potentimmunosuppressant

    Adult Dosage: 400-1800 mg IV Reason Receiving: diffuse large B-cell lymphoma

    Newborn Dosage: 2-3 mg/kg/day po Pregnancy Category: D

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Marked leucopenia 8-15 days afterinitial therapyNausea, vomiting, alopeciaDiarrhea, darkening of skin/fingernails,stomatitis, headache, diaphoreis

    Monitor cbc, serum uric acid, electrolytesMonitor WBCMonitor for hematologic toxicity (fever,sore throat, signs of local infection,unusual bruising/bleeding)

    Generic Name: dantrolene sodium Trade Name: Dantrium

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    Classification: skeletal muscle relaxant Action: interferes with release of calcium ion

    Adult Dosage: up to 100mg 2-4 times per day Reason Receiving: relief of spasticity due to spinal injuries

    Newborn Dosage: na Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationDrowsiness, dizziness, weakness genera lmalaise, diarrhea. HA, confusion

    constipation, Urinary frequency

    Baseline Hepatic function test ( AST,ALTalkaline phosphatase, total bilirubin) Record

    onset, type location, duration of muscularspasms. Assess for therapeutic response,relief of pain.

    No hepatic test data availablePropphylactic use due to spinal injury

    LBM-9/29/2010No confusion , dizziness, weakness,reportedUrostomy

    Generic Name: Dexamethasone Trade Name: Decadron

    Classification:Long-actingglucocorticoid/Corticosteroid

    Action:inhibits accumulation of inflammatory cells atinflammation site and release of mediators ofinflammation

    Adult Dosage: 8-20mg once, then 4mg Q4-6 Reason Receiving:Antiemetic

    Newborn Dosage: N/A Pregnancy Category:C(D if used in 1st

    trimester)

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Insomnia, facial edema

    (moonface), moderate abdominaldistension, indigestion, increasedappetite, nervousness.

    Question for hypersensitivity to any

    corticosteroids. Height, weight, BP,serum glucose, electrolytes.Assess for edema. Bowel activity

    Generic Name: Digoxin Trade Name: Lanoxin

    Classification: Cardiac Glycosides/Antiarrhythmic Action: Increase influx of calcium from extracellular to intracellularcytoplasm

    Adult Dosage: 0.5-0.75mg additional doses of 0.125-0.375mgat 6-8 hr intevals

    Reason Receiving: Treatment of CHF

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    None Known Drug:Amidarone, beta-blockers, Ca channel

    blockers, K-depletingdiuretics,symoathomimetics.Food: Fiber(bran),Pectin.

    Assess AP for 60secs. Monitorpulse for bradycardia. Assess

    for GI disturbances, neurologicabnormalities. Monitor K, Mg.

    Generic Name: diltiazem Trade Name: Cardizem

    Classification: Ca channel blocker, antihypertensive Action: InhibitsCa movement across cardiac, vascularsmooth-muscle cell membranes. Causing dilation

    Adult Dosage: 60-120 twice a day Reason Receiving: Hypertension

    Geriatric Dosage:60-120 twice a day Pregnancy Category: CSide Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Peripheral edema,dizziness, light-headedness, H/A,bradycardia, asthenia,nausea, constipation,flushing

    Beta blockers,carbamazepine,theophylline, digoxineffects

    Assess B/P and PulseAssess renal and hepaticfunction.Assist with ambulation.Dont abruptly d/c medication

    May be crushed

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    Generic Name: Diphenhydramine HCL Trade Name: Benadryl

    Classification: Ethanolamine/Antihistamine/Anticholinergic Action: Competitively blocks effects of histamine atperipheral H1 receptor sites

    Adult Dosage:25-50 mg Q4H Reason Receiving: pre med for blood

    Newborn Dosage: N/A Pregnancy Category: B

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Drowsiness, dizziness, muscleweakness, hypotension, urinaryretention, thickening of bronchialsecretions, dry mouth

    Monitor BPR- rate, depth, rhythm.

    Assess lung sounds for rhonchi,wheezing, rales.

    Generic Name: diphenoxylate HCL Trade Name: Lomotil

    Classification: antidiarrheal Action: reduces intestinal motility of gastric mucosa

    Adult Dosage: 5-15 mg/day Reason Receiving:

    Newborn Dosage: Not recommended Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Drowsiness, light-headedness,dizziness, nausea, headache, dry

    mouth

    Encourage adequate fluid intake; and,assess hydration status (skin turgor,

    mucous membranes for dryness andoutput)Assess bowel soundsMonitor bowel activity and stoolAssess for abdominal distention

    Generic Name: Docosahexanoic Acid Trade Name: Fish Oil

    Classification: Dietary supplement Action: Unknown

    Adult Dosage: 1000mg capsule Reason Receiving: CAD/HTN

    Geriatric Dosage: Same as above Pregnancy Category: Unknown

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    GI upset, diarrhea,

    increased burping, acidreflux/heartburn/indigestion,abdominal bloating,abdominal pain, fishyaftertaste.

    Drug: None Known

    Food: None Known

    Take with meals to avoid GI

    upset.

    Generic Name: Docusate Na Trade Name: Colace

    Classification: Bulk-producing laxative/Stool softener Action: Decreases surface film tension by mixing liquid withbowel contents

    Adult Dosage: 50-500mg/day in 1-4 divided doses Reason Receiving: Stool Softner

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationMild GI cramping Drug: None significant

    Food: None Known

    Encourage adequate fluid intake.Assess bowel sounds. Monitorbowel activity. Record time ofevacuation

    Generic Name: Doripenem Trade Name: Doribax

    Classification: Carbapenem/antibiotic Action: inactivates penicillin-binding proteins, resulting in inhibition of cellwall synthesis

    Adult Dosage: 500mg q8h for 10-14 days Reason Receiving: Treatment of complicated UTIs due to susceptiblegram(+), gram(-) and anaerobic bacteria

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    Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Diarrhea, nausea, HA,altered mental status

    Drug: ProbenecidFood: None Known

    Hx of allergies. Monitor bowelpattern/activity. Monitor fornausea/vomiting

    Generic Name: Doxepin HCL Trade Name: SinequanClassification: Tricyclic/Antidepressant Action: Increases synaptic concentrations of norepinephine,

    serotonin.

    Adult Dosage: 25-150mg/day at bedtime Reason Receiving: Treatment of depression

    Geriatric Dosage: 10-25mg/day at bedtime Pregnancy Category: C(B for topical form)

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Orthostatic hypotension,somnolence, dry mouth,HA, increased appetite,weight gain, nausea,unusual fatigue,unpleasant taste

    Drug:Alcohol, other CNSdepressants may increase CNS,respiratory depression,hypotensive effects. Antithyroidagents may increase risk ofagranulocytosis. Cimetidine mayincrease concentration risk oftoxicity. May decrease effects ofclonidine. MAOIs may increase

    risk of seizures, hyperpyrexia,hypertensive crisis.Phenothiazines may increaseanticholinergic, sedative effects.Sympathomimetics mayincrease cardiac effects.Food: grapefruit, grapefruit

    juice may increaseconcentration/toxicity

    Monitor B/P, pulse, weight.Supervise suicidal-risk ptclosely during earlytherapy.Therapeutic level: 110-250 ng/ml

    Generic Name: DOXOrubicin Trade Name: adriamycinClassification: anthracycline antibiotic;antineoplastic

    Action: inhibits DNA, DNA-dependent RNA synthesis by binding the DNAstrands; prevents cell division

    Adult Dosage: 30 mg/m Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: D

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Complete alopecia, nausea, vomiting,stomatitis, esophagitisReddish urineAnorexia, diarrhea

    Monitor for stomatitis; assess mucousmembranesMonitor daily bowel pattern and stoolconsistency.Monitor for hematologic toxicity (fever,sore throat, signs of local infection,unusual bruising/bleeding)Monitor for symptoms of anemia

    Generic Name: Enoxaparin Na Trade Name: Lovenox

    Classification: Low Molecular Weight Heparin Action: Potentiates action of antithrombin III, inactivates coagulation factorXaAdult Dosage: 1mg/kg q.12hr Reason Receiving: Prevent DVT

    Geriatric Dosage: Same as Above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Injection site hematoma,Nausea, peripheraledema

    Drug: antiplatelet agents,aspirin, NSAIDs,thrombolytics mayincrease risk of bleeding.Food: None known

    Monitor CBC, platelet count.Assess any sign of unusualbleeding(bruising, bleedingfrom gums, blood in stool).

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    Generic Name: erythromycinophthalmic ointment

    Trade Name:

    Classification: Macrolide; antibiotic Action: penetrates bacterial cell membranes, reversibly binds tobacterial ribosomes inhibiting protein synthesis

    Adult Dosage: thin layer to affectedarea bid

    Reason Receiving: prevention of gonococcal ophthalmianeonatorum, superficial ocular infections

    Newborn Dosage: 0.5-2 cm no laterthan 1 hour after deliver

    Pregnancy Category: B

    Side Effects Nursing Implications R/T Adm. & S.E. Evaluation

    Sensitivity reaction withincreased irritation, burning,itching, inflammation

    Urticaria

    Place gloved finger on lowereyelid and pull out; place to inch of ointment in; close eyegently for 1-2 minutes

    Monitor daily pattern of bowelactivity

    Assess skin for rash

    Assess for hepatotoxicity

    (malaise, fever, abdominal pain,GI disturbances)

    Be alert for superinfection (fever,vomiting, diarrhea, oral mucosalchanges)

    Monitor for high-dose hearingloss

    Generic Name: Escitalopram Oxalate Trade Name: Lexapro

    Classification: Serotonin reuptakeinhibitor/antidepressant

    Action: Blocks uptake of neurotransmitter serotonin at neuronalprsynaptic membranes, increasing its availability at postsynapticreceptor sites

    Adult Dosage: Initially 10mg/day, increase to 20mg after a minof 1 wk.

    Reason Receiving: depression

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Nausea, dry mouth, somnolence,insomnia, diaphoresis

    Assess appearance, behavior,speech pattern, level of interest,mood.

    Generic Name: etoposide Trade Name: Etopophos

    Classification: epipodophyllotoxin;antineoplastic

    Action: induces single- and double-stranded breask in DNA; inhibits, alters DNAsynthesis

    Adult Dosage: 100 mg Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: D

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Mild to moderate nausea/vomiting,alopecia, diarrhea, anorexia, stomatitis

    Monitor Hgb, Hct, WBC, PLTMonitor bowel pattern and stoolconsistencyMonitor for hematologic toxicity (fever,sore throat, signs of local infection,

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    unusual bruising/bleeding)Monitor for symptoms of anemiaAssess for paresthesias (peripheralneuropathy)

    Generic Name: FeFum/Vit C/B12/stomc Trade Name: ChromagenClassification: multivitamin with iron Action: replace iron and vitamins

    Adult Dosage: 1 tablet per day Reason Receiving:

    Geriatric Dosage: same Pregnancy Category:

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    ConstipationDiarrheaStomach upset

    AntacidsCefdinirCefditorenEtidronateFluoroquinolonesLevodopaTetracyclinesThyroid hormones

    WarfarinDairy products, tea orcoffee within 2 hours

    Take with glass of waterMay take with food, but best onempty stomachDo not lie down for 30 minutesafter taking

    Generic Name: fentanyl Trade Name: (sublimaze)

    Classification: narcotic agonist(schedule II) Action: binds to opioid receptors in CNS reducing stimuli fromsensory nerve endings, inhibits ascending pain pathways;alters pain reception

    Adult Dosage:50-100mcg/dose q1-2h Reason Receiving: abdominal pain

    Newborn Dosage: Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Post-op confusion, blurred vision, chills,orthostatic hypotension, nausea, vomiting,

    diaphoreses, Dyspnea, confusion,constipation

    Have nalozone available. Establishbaseline, BP, R. Assess type, location,

    intensity, duration of pain.

    Not given in last 24 hours.

    Generic Name: Fentanyl Patch Trade Name:

    Classification: Opioid, narcotic agonist (sch. II) Action: Binds to opioid receptors in CNS

    Adult Dosage: 12mcg/hr-100mcg/hr Reason Receiving: analgesic for pain

    Newborn Dosage: Pregnancy Category: C

    Side Effects Nursing Implications R/TAdministration & Side Effects Evaluation

    Headache, pruritus, NV, diaphoresis,Dyspnea, confusion, dizziness,diarrhea, constipation, difficultyurinating.

    Assist with ambulation. Opiateantagonist(narcan) must be available.

    Assess BP, HR, Respirations, O2stats. type, location, intensity, durationof pain. Encourage to deep breatheand turn q2h.

    Patch assessed-BPHRO2

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    Generic Name: Na Ferric Gluconate Trade Name: Ferrex

    Classification: Trace element/Hematinic Action: Repletes total iron content in body. Replaces iron found in Hgb,myoglobin. Specific enzymes; allows oxygen transport via Hgb.

    Adult Dosage: 125mg in 100mL 0.9% NaCl infused over 1 hr Reason Receiving: Treatment of iron deficiency anemia

    Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Flushing, hypotension,hypersensitivity reaction Drug: Oral IronFood: None Known Monitor vital signs, labs (i.e.CBC, serum iron). Do not givewith oral iron. Assess pt for RA,may exacerbate joint pain,swelling.

    Generic Name:Fexofenadine HCL Trade Name:Allegra

    Classification:Antihistamine Action: prevents allergic rhinitis symptoms or pruritus

    Adult Dosage: 60 mg twice a day Reason Receiving: allergies

    Newborn Dosage: Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Rare: drowsiness, HA, fatigue,nausea, abdominal distress.

    Assess for therapeutic response. Pt reported a decrease in allergicrhinitis symptoms.No c/o of fatigue Nausea, GIdistress

    Generic Name:Filgrastin Trade Name: Neupogen

    Classification: Granulocyte Colony Stimulanting factor Action: Stimulates production, maturation, activation ofneutrophils

    Adult Dosage: 5mcg/kg/day Reason Receiving: Prevent infection

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Nausea/Vomiting, Mild to severebone pain, Diarrhea, Fever, fatigue

    Be alert to ARDS. Monitor b/p,temp, CBC, plts count, Hct, uricacid

    Generic Name: Finasteride Trade Name: Proscar

    Classification: Androgen hormone inhibitor/Benignprostatic hyperplasia agent

    Action: Inhibits 5-alpha reductase, an intracellular enzyme that convertstestosterone into dihydrotestosterone (DHT) in prostate gland, resu;ting in

    decreased serum DHTAdult Dosage: 5mg once a day Reason Receiving: BPH

    Geriatric Dosage: Same as Above Pregnancy Category: X

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Gynecomastia, sexualdysfunction(impotence,decreased libido,decreased vol ofejaculate).

    Drug: None SignificantFood: None Known

    Diligent monitoring of I&O, espin those with lg residual urinaryvol, severely diminished urinaryflow for obstructive uropathy

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    Generic Name: Fluconazole Trade Name: Diflucan

    Classification: antifungal Action: directly damages fungal membrane

    Adult Dosage: 400mg perday Reason Receiving: prevention of candidiasis

    Newborn Dosage: Pregnancy Category: C

    Side Effects

    Nursing Implications R/T

    Administration & Side Effects EvaluationDizziness, HA, constipation, diarrhea,nausea, vomiting, abdominal pain

    Establish baselines for CBC serumpotassiumHepatic function studies

    K-3.9(normal 3.5-5)No Pt complaints of dizziness, HA,Constipation, diarrhea, NV,abdominal pain

    Generic Name: fluoxetine Trade Name: Prozac

    Classification: psychotherapeutic Action: selectively inhibits serotonin uptake in CNS, enhancingserotonergic function; relieves depression, obsessive-compulsive and bulimic

    Adult Dosage: 20 mg Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Headache, asthenia, insomnia,anxiety, drowsiness, nausea, diarrhea,decreased appetiteDizziness, tremors, fatigue, vomiting,constipation, dry mouth, abdominalpain, diaphoresis, rash

    Assess appearance, behavior, speechpattern, level of interest, moodMonitor daily bowel pattern and stoolconsistencyAssess skin for rashMonitor glucose, sodium and weight

    Generic Name: Fluticasone Trade Name: Advair

    Classification: Corticosteroid/Anti-inflammatory Action: Controls rate of protein synthesis, depresses migration ofpolymorphonuclear leukocytes, reverses capillary permeability, stabilizeslysosomal membranes.

    Adult Dosage: 100mcg q.12h Reason Receiving: COPD

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Throat irritation,hoarseness, dry mouth,cough, temporarywheezing, oropharyngealcandiasis (particularly ifmouth is not rinsed withwater after each admin.)

    Drug: RitonavirFood: None Known

    Monitor rate, depth, rhythm,type of respiration. Assess lungsounds. Assess oral mucousmembranes. Monitor pulse.

    Generic Name: Folic Acid Trade Name: Folvite

    Classification: Coenzyme/Nutritional Supplement Action: Stimulates production of platelets, RBCs, WBCs

    Adult Dosage: 0.4mg/day Reason Receiving:Anemia

    Newborn Dosage: 0.1mg/day Pregnancy Category: Category:A(C if more thanRDA)

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    None Known Assess for therapeutic relief fromiron deficiency symptoms(fatigue,

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    SHOB, sore tongue, HA, pallor)

    Generic Name: Furosemide Trade Name: Lasix

    Classification: Loop Diuretic Action: Excretion of Na, Cl, K by direct action at the ascending loop ofhenle

    Adult Dosage: 20-80mg/dose; may increase by 20-40 mg/dose q.6-8h

    Reason Receiving: HTN

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Increase UOP, frequency,Nausea, dyspepsia,abdominal cramps,diarrhea or constipation,electrolyte imbalance

    Drug:Amphotericin B,nephrotoxic, ototoxicmeds, anticoagulants,heparin, lithium, othermed causinghypokalemiaFood: None Known

    Monitor B/P, vital signs,electrolytes, I&O, weight.Assess muscle strength,tremor, muscle cramps, alteredmental status.

    Generic Name: Gabapentin Trade Name: Neurontin

    Classification:Anticonvulsant/Antineuralgic Action: May increase synthesis or accumulation of gamma-aminobuytricacid(GABA) by binding to as-yet-undefined receptor sites in brain tissue

    Adult Dosage: 200mg Reason Receiving: Neuropathy pain

    Geriatric Dosage: N/A Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Fatigue, drowsiness,dizziness, ataxia

    Drug:Antiacids decreaseabsorption. Morphine mayincreaseCNS depression.Food: None known

    Monitor for seizure activity. Donot abruptly stop taking

    Generic Name: glipizide Trade Name: Glucotrol

    Classification: 2nd generation. Hypoglycemic Action: Promotes release of insulin from beta cells ofpancreases, insulin sensitivity at peripheral sites

    Adult Dosage: 5mg daily Reason Receiving: DM Type II

    Geriatric Dosage: 2.5 mg daily Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Altered taste, dizziness,somnolence, weight gain,constipation, diarrhea,heartburn, nausea,vomiting, H/A

    Beta blockers, MAOIS,ciprofloxacin, ranitidine,LG doses of salicylates effects.Corticosteroids, lithium,thiazide diuretics effects. effects of oral

    anticoagulants

    Check serum glucose level.Assess for hypoglycemia andhyperglycemia.

    Generic Name: glyburide Trade Name: Diabeta

    Classification: second generation sulfonylurea Action: hypoglycemic

    Adult Dosage: 2.5-5 mg; max 20 mg/day Reason Receiving: diabetes mellitus type 2

    Geriatric Dosage: 1.25-2.5 mg/day Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Altered taste, dizziness, Beta blockers, cimetidine, Check serum glucose

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    somnolence, wt gain,constipation, diarrhea,heartburn, N&V,headachePhotosensitivity, skin rash

    ciprofloxacin, fluconazole,MAOIs, ranitidine,salicylates,corticosteroids, lithiumthiazide diuretics; Garlic

    Assess learning needsAssess for hypoglycemia

    Generic Name: guar gum Trade Name: Benefiber

    Classification: soluble fiber Action: dissolves in water for form gel-like material that passes through stomach,small intestine, colon and out of body; helps to lower blood cholesterol and glucoselevels

    Adult Dosage: 2 tsp 3x qd Reason Receiving:Newborn Dosage: ask MD before use Pregnancy Category:

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Generally well toleratedBloating, diarrhea, gas and generaldiscomfort

    Assess bowel pattern and stool consistencyAssess abdomen for bloating

    Generic Name: heparin Trade Name: Hep-Lock

    Classification: blood modifier; anticoagulant Action: Interfers with blood coagulation by blocking conversion of PTto thrombin and fibrinogen to fibrin

    Adult Dosage: 5000 units Reason Receiving:

    Geriatric Dosage: Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Pruritus, burning (soles offeet)

    Antithyroid; valproic acid;other anticoagulants,cats claw, eveningprimrose, ginkgo,

    Monitor PTT (1.5-2.5)Assess hct, plt count, ast, altAssess for decrease in BP,increased pulse, complaint ofback pain, severe headacheAssess peripheral pulsesAssess skin for ecchymosis,petechiaeCheck for excessive bleeding

    Generic Name: Hydralazine Trade Name: Apresoline

    Classification: Vasodilator/Antihypertensive Action: Direct vasodilating effects on arterioles.

    Adult Dosage: 10mg 4X/day Reason Receiving: HTN

    Geriatric Dosage: 10mg 2-3X/day Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    HA, palpitations,

    tachycardia

    Drug: Diurectics, other

    hypertensives.Food: None Known

    Monitor B/P, pulse before

    admin. Assess for HA,palpitations, tachycardia,peripheral edema.

    Generic Name: Hydrocortisone Sod Trade Name:

    Classification: adrenal corticosteroid Action: inhibits inflammatory cells at inflammation sites.

    Adult Dosage: 14-240 mg Q12H Reason Receiving: anti-inflammatory

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    Newborn Dosage: na Pregnancy Category: na

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Insomnia, Heartburn, anxiety,abdominal distention, increasedappetite, increased susceptibility toinfection, diarrhea or constipation. HA,

    edema, frequent urination.

    Baseline weight, BP, serum glucose,cholesterol electrolytes.

    Assess for edema. Be alert to infection.Monitor daily bowel pattern.

    Electrolytes.Watch for hypercalcemia (muscletwitching, cramps) Hypokalemia(weakness, paresthesias)

    Generic Name: Hydrocortisone topical Trade Name:

    Classification: Glucocortosteroid Action: prevents tissue response to inflammatory process

    Adult Dosage: apply sparingly Reason Receiving: rash

    Newborn Dosage: Pregnancy Category:C

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationPruritus, redness irritation. Monitor for therapeutic relief. Pt. stated some relief. Patient applied

    AM 9/23/10

    Generic Name: hydrocodone Trade Name: VicodinClassification: opiod analgesic (sch. III); narcotic analsegic Action: binds with opioid receptors within CNS; alters pain

    Adult Dosage: 5-15 mg q4-6h prn Reason Receiving: post-op pain

    Geriatric Dosage: same Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Sedation, dizziness,diaphoresis, facialflushing, somnolenceurinary retention, blurredvision, constipation, drymouth, headache, N & V,

    painful/difficult urination

    CNS depressantsMAOIsAlcoholKava kava, St. JohnsWort, valerian

    Assess pain (level, location,duration, description)Assess for therapeuticresponseObtain VS before givingAssess for urinary retention

    Monitor bowel activity and stoolconsistencyInitiate deep breathing/cough

    Generic Name: Hydroxyzine Trade Name: Atarax

    Classification:Antihistamine/antipruritis Action: Competes with histamine for receptor sites in GI tract, bloodvessels, respiratory tract. Diminishes vestibular stimulation, depresseslabyrinthine function.

    Adult Dosage: 25mg 3-4X/day Reason Receiving: Itching

    Geriatric Dosage: Same as above Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Drowsiness, dry mouth,

    marked discomfort withIM injection

    Drug:Alcohol, other CNS

    depressants, MAOIsFood: None Known

    Monitor electrolytes, Assess

    motor responses, hepatic/renalfunction tests, lung sounds

    Generic Name: ibuprofen Trade Name: Motrin

    Classification: nonsteroidal anti- Action: produces analgesic, anti-inflammation effects,

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    inflammatory decreases fever

    Adult Dosage: 200-400 q4-6h prn Reason Receiving: inflammation of the labia

    Newborn Dosage: safety and efficacynot established in those younger than6 months

    Pregnancy Category: B (D if in third trimester or near delivery)

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Nausea with or withoutvomiting

    Dyspepsia

    Dizziness

    Rash

    Assess onset, type, location,duration of pain, inflammation

    Inspect appearance of affectedjoints for immobility, deformities,skin condition

    Assess temp

    Monitor for evidence of nauase,dyspepsia

    Monitor CBC, hepatic/renalfunction tests

    Monitor daily pattern of bowelactivity

    Assess for skin rash

    Assess for therapeutic response Monitor temp for fever

    Generic Name: Ipratropium Trade Name: Atrovent

    Classification:Anticholinergic/Bronchodilator Action: Blocks action of acetylcholine at parasympathic sites in bronchialsmooth muscle.

    Adult Dosage: 500 mcg 3-4 times/day Reason Receiving: Treatment of bronchospasm

    Geriatric Dosage: Same as above Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Cough, dry mouth, HA,nausea

    Drug:Anticholinergics,meds with anticholinergicproperties.

    Food: None Known

    Monitor rate, depth, rhythm,type of respirations and pulse.Assess lung sounds. Increase

    fluids. Rinse mouth with waterafter inhalation.

    Generic Name: Hydromorphone Trade Name: Dilaudid

    Classification: opioid agonist(sch II) Action: binds to opioid receptors in CNS

    Adult Dosage:10mg/ml Reason Receiving: pain relief

    Newborn Dosage: Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Drowsiness, dizziness, hypotension,decreased appetite,

    Vital signs bf giving meds. Assess forpain relief, cough. Assess breathsounds. Monitor bowel activity. Initiatedeep breathing and cough exercises.

    TPR-BPLungsLBMPain decreasedCoughing

    Generic Name:Isosorbide mononitrate Trade Name: ImdurClassification:Antianginal Action:stimulates intracellular cyclic guanosine

    monophosphate

    Adult Dosage: 5-20mg BID Reason Receiving: Relief of esophageal spasm withgastroesophageal reflux

    Geriatric Dosage: Same as above Pregnancy Category: C

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    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    HA, face/neck flushing,weakness, dizziness,orthostatic hypotension,N&V, restlessness,blurred vision, and GI

    upset

    Drug: ETOH,antihypertensives,vasodilators, Sildenafil,tadalafil, vardenafil.Food: None Known

    Best if taken on an emptystomach, assess for facial/neckflushing, assess pain

    Generic Name: Insulin Aspart/Insulin Glargine Trade Name: Novolog/Lantus

    Classification: Exogenous insulin Action: Facilitates passage of glucose, K, Mg across cellular membranes ofskeletal/cardiac muscle, adipose tissue. Controls storage, metabolism ofcarbs, protein, fats. Promotesconversion of glucose to glycogen in liver.

    Adult Dosage: 0.5- 1 unit/kg/day Reason Receiving: DM

    Geriatric Dosage: Same as above Pregnancy Category: B/C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Localized redness,swelling itching. Adversereaction- severehypoglycemia

    Drug: Beta-blockers,Glucocorticoids, Thiazidediuretics.Food: None Known

    Assess for hypoglycemia: cool, wetskin, tremors, dizziness, HA, anxiety,tachycardia, numbness in the mouth,hunger, diplopia. Assess forhyperglycemia: polyuria, polyphagia,polydipsia, N/V, dim vision, fatigue,

    Kussmaul Resp.

    Generic Name: Labetalol HCL Trade Name: Trandate

    Classification:Alpha-, beta-adrenergicblocker/antihypertensive

    Action: Blocks alpha1-, beta1-, beta2-(large doses) adrenergicreceptor sites. Large doses increase airway resistance.

    Adult Dosage: Initially, 100mg BID adjust in increments of 100mg BID q2-3days

    Reason Receiving: hypertension

    Newborn Dosage: N/A Pregnancy Category: C(D if used in 2nd or 3rd trimester)

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Drowsiness, difficulty sleeping,excessive fatigue, weakness,diminished sexual function,transient scalp tingling.

    Assess renal/hepatic functionBP, Apical Pulse immediately bf drugadministration. If pulse less than 60 or

    systolic less than 90 hold med. Contactphysical

    Generic Name: lamotrigone Trade Name: Lamictal

    Classification: anticonvulsants Action: may block sodium channels, stabilizing neuronal membranes; producesanticonvulsant activity

    Adult Dosage: 200 mg/day Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Dizziness, headache, diplopia, ataxia,nausea, blurred vision, somnolence,rhinitis

    Rash, pharyngitis, vomiting, cough, flu-like symptoms, diarrhea, fever,insomnia

    Assess for rashAssist with ambulation if dizzyAssess for clinical improvement.

    Assess for visual abnormalities,headache

    Generic Name: Leucovorin Calcium Trade Name: Wellcovorin ???

    Classification: folic acid antagonist Action: competes with methotrexate for transport into cell

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    Adult Dosage: 5-15 mg per day Reason Receiving: folic acid deficiency???non hodgkins

    lymphomaNewborn Dosage: na Pregnancy Category: na

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    When combined with

    chemotherapeutic agents, diarrhea,stomatitis, NV lethargy Malaisefatigue.

    Give as soon as possible, preferably

    within one hour, for treatment ofoverdose of folic acid antagonist.Monitor for vomiting. CBC with diff.PLT, Electrolytes, Hepatic functiontests.

    Generic Name:Levetiracetam Trade Name: Keppra

    Classification:Anticonvulsant Action:Inhibits burst firing without affecting normal neuronalexcitability

    Adult Dosage:Initially 500mg q.12h Reason Receiving:

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Drowsiness, asthenia(loss ofenergy), HA, infection.

    Hx of seizure disorder. Monitor forhypersensitivity. Monitor renalfunction tests.

    Generic Name: Levothyroxine Trade Name: Synthroid

    Classification: Thyroid Hormone Action: Involved in normal metabolism, growth, development,esp. of CNS in infants. Possesses catabolic, anabolic effects.

    Adult Dosage:150 mcg Reason Receiving:Hypothyroidism

    Geriatric Dosage:25 mcg Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    HA, allergic rhinitis, upperrespiratory infection,muscle pain, fatigue

    Drug: Cholestryramine,colestipol, estrogens, oralanticoagulants,sympathomimetics, H2antagonist, proton pumpinhibitors.Food: None Known

    Obtain weight, Monitor pulse,observe for anxiety andtremors, assess appetite andsleep pattern

    Generic Name: lidocaine patch Trade Name: Lidoderm

    Classification: antiarhythmic anesthetic Action: inhibits conduction of nerve impulses

    Adult Dosage: one patch Reason Receiving:

    Geriatric Dosage: one patch Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Burning, stinging,

    tenderness at applicationsite

    Anticonvulsants, beta

    blockers, otherantiarrhythmics, St.Johns wart

    Monitor VS following

    administrationAssess BP for hypotensionAssess for drowsiness (sign ofhigh serum levels)

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    Generic Name: linezolid Trade Name: Zyvox

    Classification: antibiotic Action: protects against bacteria (enterococci, staphylococci, streptococci)

    Adult Dosage: 400 mg q12h Reason Receiving:

    Newborn Dosage:10 mg/kg/dose q8-12h Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Diarrhea, nausea, headache Monitor daily bowel pattern/stoolconsistency; mild GI effects may be okaybut more severe be alert to colitisBe alert for superinfectionMonitor CBC weekly

    Generic Name: Lisinopril Trade Name: Zestril

    Classification: ACE inhibitor Action: suppresses RAA system to help lower BP

    Adult Dosage: 10-40 mg/day Reason Receiving:

    Geriatric Dosage: 10-40 mg/day Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Headache, dizziness,postural hypotensionChest discomfort, fatigue,rash, abdominal pain,nausea, diarrhea, URI

    Alcohol, diuretics,hypotensive agents (mayincrease effect).Lithium, NSAIDs, K-sparring diuretics.Ephedra, ginseng,yohimbe

    Obtain BP & apical pulse priorMonitor BP regularlyWatch for orthostatic HTNMonitor CBC, renal, potassiumAssess for edema.Auscultate lungs for ralesMonitor I&O; weigh dailyMonitor bowel patternAssist with ambulation if dizzy

    Generic Name: lithium carbonate Trade Name: Lithobid

    Classification: psychotherapeutic; antimanic Action: affects storage, release, reuptake of neurotransmitters;increased reuptake of norepi causing antimanic effect

    Adult Dosage: 300 mg 3-4 times q.d. Reason Receiving: manic phase of bipolar disorder

    Geriatric Dosage: 900-1200 mg/day Pregnancy Category: D

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Dose related and seldomoccur at lithium serumlevels less than 1.5mEq/LOccasionally, fine handtremor, polydipsia,polyuria, mild nausea

    Haloperidol, antithyroidmeds, diuretics, NSAIDs,molindone,phenothiazines

    Monitor serum lithium levelsClinical assessment oftherapeutic effect; assessbehavior, appearance,emotional status, response toenvironment, speech pattern,thought content.Monitor for signs of lithiumtoxicity

    Generic Name: loperamide Trade Name: Imodium

    Classification: antidiarrheal Action: slows intestinal motility, diminishing loss of fluid/electrolytes

    Adult Dosage: 2 mg after loose stool Reason Receiving: cancer treatment-induced diarrhea

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    Newborn Dosage: not recommended Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Rare: Dry mouth, drowsiness, abdodiscomfort, allergic reaction

    Encourage adequate fluid intakeAssess bowel soundsMonitor daily bowel activity/stool

    Withhold if abdo pain, distention, fever

    Generic Name: Lorazepam Trade Name: Ativan

    Classification: Benzodiazepine (Sche IV)/Antianxiety Action: Enhances action of inhibitory neurotransmittergamma-aminobutyric acid (GABA) in CNS, affecting memory,motor, sensory, cognitive functioning

    Adult Dosage: 1-10mg/day in 2-3 divided doses Reason Receiving: Treatment of anxiety related todepressive episode

    Geriatric Dosage: 0.5-1.0mg/day Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    HA, fatigue, drowsiness Drug: Clarithromycin,erythromycin,fluconazole, ketoconazolemay increaseconcentration. Food:Allfoods delay absorption.

    Monitor BP, HR, RR,CBC with diff, Hepatic functionest. Evaluate for therapeuticresponse

    Generic Name: magnesium hydroxide Trade Name: Milk of Magnesia

    Classification: antacid, anticonvulsant, electrolyte, laxative Action: acts in stomach to neutralize gastric acid; osmotic effectprimarily in small intestine, draws water into intestinal lumen

    Adult Dosage: 2-4 tabs or 5-15 mL prn 4 times a day Reason Receiving:

    Geriatric Dosage: same Pregnancy Category: BSide Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    CrampingDiarrheaIncreased thirstFlatulence

    AntacidsFluoroquinolonesKetoconazoleTetracyclinesCalciumCNS depressant medsDigoxin

    Drink full glass of water withdoseMonitor daily bowel activity andstool consistencyBS for peristalsisAssess for wt loss, nausea,vomiting

    Generic Name: Magnesium Oxide Trade Name: Mag-ox

    Classification:

    Antacid/Anticonvulsant/Electrolyte/Laxative

    Action: Essential for enzyme activity, nerve conduction,

    muscle contractionAdult Dosage: 1-2 tablets 2-3x/day Reason Receiving: Magnesium replacement

    Geriatric Dosage: Pregnancy Category: B

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Chalky taste, diarrhea,laxative effect, N/V,stomach cramps, reducedresp rate, decreasedreflexes, flushing,

    Drug:Antacids,fluoroquinolones, ketoconazole,tetracyclines, methenamine,laxatives, digoxin, oralanticoagulants, phenothiazines,ciprofloxacin, Na polystyrene

    Assess renal function. MonitorMg. Monitor forhypermagnesemia: dizziness,palpitations, altered mentalstatus, fatigue, weakness.

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    hypotension, decreasedheart rate

    sulfonate, Calcium, CNSdepressants meds.Food: None Known

    Generic Name: magnesium sulfate Trade Name:Classification: antacid, anticonvulsant,electrolyte, laxative

    Action: found primarily in intracellular fluids

    Adult Dosage: 3 g q6h for 4 doses as needed;IV 4 g then 1-4 g/hr by cont. infusion

    Reason Receiving: protocol for magnesium deficiency

    Newborn Dosage: not used (12yrs+) Pregnancy Category: B

    Side Effects Nursing Implications R/T Adm. & S.E. Evaluation

    Chalky tasteDiarrheaLaxative effectNausea and vomitingStomach crampsReduces respiratory rateDecreases reflexesFlushingHypotension

    Decreased heart rate

    Assess GI painMonitor daily pattern of bowel activityand bowel soundsAssess renal function, serummagnesiumAssess pt for weight loss, nausea,vomitingMonitor renal functionMaintain adequate fluid intake

    Test patellar reflexesRespiratory rate should be over 16

    Generic Name: medroxyprogesterone Trade Name: Depo-Provera

    Classification: hormone Action: inhibits secretion of pituitary gonadotropins; preventsovulation

    Adult Dosage: 5-10 mg for 12-14consecutive days

    Reason Receiving: birth control

    Newborn Dosage: safety and efficacynot established

    Pregnancy Category: X

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Transient menstrualabnormalities (spotting,

    amenorrhea) Edema

    Weight change

    Breast tenderness

    Anxiety

    Insomnia

    Fatigue

    Dizziness

    Depression

    Caution in nursing mothers;distributed in breast milk

    P.O. give without regard tomeals

    Check weight and report gain of5 pounds or more

    Assess for skin rash, urticaria

    Report development of chestpain, sudden SOB, decrease invision, migraines, pain in calves,numbness of arm/leg

    Generic Name: megestrol acetate Trade Name: MegaceClassification: antineoplastic/hormone Action: suppresses release of LH from ant. pituitary by inhibiting pituitary

    function thus reducing tumor size; also increases appetiteAdult Dosage: 800 mg Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: X

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Weight gain secondary to increasedappetiteNausea, break through bleeding,backache, headache, breasttenderness, carpal tunnel syndrome

    Question possible pregnancyProvide support as med is palliative notcurativeMonitor for tumor response

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    Generic Name: methylergonovinemaleate

    Trade Name: Methergine

    Classification: ergot alkaloid; uterine

    stimulant

    Action: stimulates alpha-adrenergic, serotonin receptors, producing

    arterial vasoconstriction; acts on the smooth muscle of uterus andincreases tone, rate and amplitude of rhythmic contractions; shortensthird stage of labor and reduces blood loss

    Adult Dosage: 0.2 mg 3 or 4 timesdaily for max of 1 week

    Reason Receiving: prevention/control of postpartum hemorrhage

    Newborn Dosage: safety andeffectiveness has not been established

    Pregnancy Category: C

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    Uterine cramping

    Nausea and vomiting

    Diarrhea

    Diaphoresis

    Tinnitus

    Bradycardia

    Chest pain

    Dizziness

    Should not be administered IV

    Caution if nursing mother

    Assess bleeding beforeadministration

    Monitor uterine tone, bleeding,

    BP, pulseq15 minutes untilstable

    Assess extremities for color,warmth, movement, pain

    Report chest pain promptly

    Provide support with ambulationif dizziness occurs

    Generic Name:Methylphenidate HCL Trade Name: Concerta

    Classification:CNS stimulant (Sche II) Action: Blocks reuptake of norepinephrine, dopamine intopresynaptic neurons.

    Adult Dosage: Initially 0.3mg/kg/dose or 2.5-5mg beforebreakfast and lunch

    Reason Receiving:ADHD

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Anxiety, insomnia, anorexia Avoid caffeine. Monitor CBC,Platelet count during therapy.

    Generic Name: Metoprolol tartate Trade Name: Lopressor

    Classification: Beta-adrenergicblocker/Antihypertensive

    Action: Selectively blocks beta-adrenergic receptors; high dosages mayblock beta-adrenergic receptors. Decrease oxygen requirements. Large dosesincrease airway resistance.

    Adult Dosage: : 25 mg per day , max 300 mg perday Reason Receiving:Geriatric Dosage: Pregnancy Category:

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationDiminished sexual function,drowsiness, insomnia,unusual fatigue/weakness

    Drug:Diuretics, otherantihypertensives, insulin.Oral hypoglycemic,NSAIDs,Sympathomimetics,Xanthines.

    Assess renal/hepatic functionBP, Apical Pulse immediately bfdrug administration. If pulse lessthan 60 or systolic less than 90hold med. Contact physical

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    Food: None Known

    Generic Name: Metoclopramide Trade Name: Reglan

    Classification: Peristaltic stimulant/Antiemetic Action: Stimulates motility of upper GI tract. Decreases reflux intoesophagus. Raises threshold activity in chemoreceptor trigger zone.

    Adult Dosage: 10-20mg q.4-6h Reason Receiving:

    Geriatric Dosage: Pregnancy Category:Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Drowsiness,restlessness, fatigue,lethargy

    Drug: ETOH, other CNSdepressants.Food: None Known

    Assess for dehydration. MonitorB/P & HR. Assess forperipheral edema. Assessmuscle strength, mental status.

    Generic Name: Metronidazole Trade Name: Flagyl

    Classification: Nitroimidzole derivative Action: Disrups DNA, inhibiting nucleic acid synthesis

    Adult Dosage: 500-750mg, 3 times a day Reason Receiving: antibacterial

    Newborn Dosage: Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Anorexia, nausea, dry mouth, metallic

    taste, diarrhea, constipation, reddish

    brown urine. Erythematous rash,

    urticaria.

    Question for history for

    hypersensitivity to nitromidazole

    derivatives. I&O assess for urinary

    problems. Assess for rash. Watch for

    signs of supervirus.

    No history of hypersentivity to

    nitromidazole derivatives. Patient

    NPO. Output not being monitored. No

    rashes or signs of infection.

    Generic Name:Micafungin Na Trade Name: Mycamine

    Classification:Antifungal Action:Inhibits synthesis of glucan(vital component of fungal cell

    formation), damaging fungal cell membrane.Adult Dosage:100mg/day Reason Receiving: for candidiasis

    Newborn Dosage: N/A Pregnancy Category: C

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Nausea, HA, diarrhea, vomiting,fever

    Hepatic/renal function tests

    Generic Name: Minocycline HCL Trade Name: Minocin

    Classification: Tetrcycline- antibiotic Action: inhibits bacterial protein synthesis b binding toribosomes.

    Adult Dosage: 100mg Q12H Reason Receiving: infectionNewborn Dosage: na Pregnancy Category: D

    Side EffectsNursing Implications R/T

    Administration & Side Effects EvaluationDizziness, light headedness, diarrhea,nausea, vomiting, possibly severephotosentivity, vertigo

    Question for history of allergies, esp.tetracyclines, sulfite. Monitor Bowel activity.

    Assess skin fo rash. Observe for sign ofincreased intracranial pressure(alteredLOC)

    No allergies to tetracycline, sulfite.LBM 9/29/2010No reports of dizziness, lightheadness,No rash

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    Generic Name: Miracle Mouthwash Trade Name: Miracle Mouthwash

    Classification:Antibiotic/Antifungal Action: Kills bacteria or prevents fungal growth

    Adult Dosage: 5ml 3-4 times/day Reason Receiving: Treatment of mouth sores

    Geriatric Dosage: Same as above Pregnancy Category: Unknown

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Problem with taste,burning or tinglingsensation in the mouth,drowsiness, constipation,diarrhea, nausea.

    Drug: None KnownFood: None Known

    Swish for 1-2 mins beforespitting out. Pt can not eat ordrink for 30mins after admin.

    Generic Name: Mirtazapine Trade Name: Remeron

    Classification: Tetracyclic/Antidepressant Action:Acts as antagonist at presynaptic alpha-adrenergic receptors,increasing norepinephrine, serotonin neurotransmission. Has lowanticholinergic activity.

    Adult Dosage: 15mg at bedtime Reason Receiving: Treatment of depression

    Geriatric Dosage: Same as above Pregnancy Category: CSide Effects Drug/Food Interactions NI R/T Adm, SE, Interactions EvaluationDrowsiness, dry mouth,increased appetite,constipation, weight gain.

    Drug: ETOH, Other CNSdepressants, MAIOs.Food: None Known

    For long term therapy,hepatic/renal function tests, bloodcounts should be performedperiodically

    Generic Name: misoprostol Trade Name: Cytotec

    Classification: prostaglandin; gastricprotection

    Action: reduces acid secretion from gastric parietal cells

    Adult Dosage: 110 mcg and 200 mcgtablets

    Reason Receiving: treatment of therapeutic second-trimesterabortion, cervical ripening, induction of labor

    Newborn Dosage: safety no

    established

    Pregnancy Category: X

    Side Effects Nursing Implications R/T Adm. & S.E. Evaluation

    Produces uterine contractions,uterine bleeding, expulsion ofPOC

    Abdominal pain

    Diarrhea

    Nausea

    Flatulence

    Dyspepsia

    Headache

    Give with or after meals(minimizes diarrhea)

    Question possible pregnancybefore giving

    Generic Name: modafinil Trade Name: ProvigilClassification: alpha1 agonist; antinarcoleptic Action: binds to dopamine reuptake carrier sites, increasing alpha

    activity, and decreasing delta, beta, theta brain wave activity; reducessleep episodes

    Adult Dosage: 200 mg/day Reason Receiving: depression (off label)

    Geriatric Dosage: 100 mg/day Pregnancy Category: C

    Side Effects Drug/Food Interactions NI R/T Adm, SE, Interactions Evaluation

    Anxiety, insomnia,nauseaAnorexia, diarrhea,

    Cyclosporine, oralcontraceptives,theophylline, diazepam,

    Monitor sleep pattern, evidenceof restlessness during sleepAssess for dizziness, anxiety;

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    dizziness, dry mouth/skin,muscle stiffness,polydipsia, rhinitis,paresthesia, tremor,headache, vomiting

    phenytoin, propranolol,tricyclic, antidepressants,warfarin, other CNSstimulants

    initiate fall precautions.Use sugarless gum and sips ofwater for relief of dry mouth

    Generic Name: montelukast Trade Name: Singulair

    Classification: leukotriene receptorinhibitor; antiasthmatic

    Action: bind to leukotriene receptors, inhibiting effects of leukotrienes onbronchial smooth muscle; decreases bronchoconstriction, vascularpermeability, mucosal edema, mucus production

    Adult Dosage: 10 mg/day Reason Receiving:Newborn Dosage: safety not established Pregnancy Category: B

    Side Effects Nursing Implications R/T Adm. & S. E Evaluation

    HeadacheInfluenza

    Monitor rate, depth, rhythm, type ofrespirationsMonitor quality/rate of pulseAssess lung sounds for rhonchi,wheezes, ralesObserve for cyanosis

    Generic Name:Morphine Sulfate Trade Name: MS Contin

    Classification: Narcotic Agonist/Opiate Analgesic(Sche II)

    Action: Binds with opioid receptors within CNS

    Adult Dosage: Use prompt-release formationguidelines

    Reason Receiving: Pain Relief

    Newborn Dosage:N/A Pregnancy Category:C(D if used for prolonged pds or at

    high dosages)

    Side EffectsNursing Implications R/T

    Administration & Side Effects Evaluation

    Sedation, decreased b/p(including

    orthostatic hypotension),diaphoresis, facial flushing,constipation, dizziness,drowsiness, nausea, vomiting

    Assess onset, type, location,

    duration of pain. Obtain vital signsbefore giving med. Monitor bowelactivity. Assess for therapeuticresponse.

    Generic Name: Moxifloxacin Trade Name: Avelox