Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013
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Transcript of Mark Lombard Sao Paulo Brazil EniFarMed Aug 2013
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North Carolina’s Life Sciences Cluster
Impact of the North Carolina Biotechnology Center
21 August 2013
Mark Lombard, MBA Program Director, Bioscience Industrial Development North Carolina Biotechnology Center
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
North Carolina, USA
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• Place – 3 major research universities in a 30 mile radius – Ecosystem of supportive organizations, risk capital,
entrepreneurial culture
• People – Collaboration among visionary business, academia, gov’t leaders – Attract and retain scientific and business talent
• Programs – Company creation, attraction, retention, expansion programs – Innovative workforce development programs
• Patience – North Carolina Biotechnology Center: 30 years – Research Triangle Park: 50+ years
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Life Sciences in North Carolina
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Brazil and North Carolina
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Brazil and North Carolina
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Sao Paulo (2012) • Population: 41,901,219
• Density: 170/km2
• GDP (2010) – US$615M
– US$15,322 per capita
• Machinery, auto and aviation, services, finance, textiles, oranges, sugar cane, coffee, life sciences
North Carolina (2012) • Population: 9,752,073
• Density: 83/km2
• GDP (2010) – $407M
– $42,884 per capita
• Cotton, tobacco, hogs, chickens, textiles, furniture
• Finance, advanced mfg, IT, life sciences
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Sao Paulo and North Carolina
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BIOTECHNOLOGY IN NORTH CAROLINA
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
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Global Challenges
• Human/Animal health
• Food availability & security
• Energy
• Environmental sustainability
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Biotechnology: Heal, Fuel, Feed the World
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Biotech in NC – Large and Diverse
• 3rd Largest Life Science Cluster in the US
– Medical Devices & Diagnostics
– Contract Research & Manufacturing
– Biopharma
– Agricultural Biotech
58%21%
21%
560+ Companies60,000+ Employees
R&D
CRO/Testing
Mfg/Prod
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Biotech in NC – Fastest Growing
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Spe
cial
izat
ion
Growth Rate
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• Average salary - $78,348
– Nearly double the state’s private sector average
• 3.6 additional jobs for each biotech job
• 226,000 total jobs
Biotech in NC – High Impact Jobs
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
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• Direct biotechnology sector revenues $41.2 billion
• Employee compensation $12.7 billion
• State and local revenues $1.92 billion
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Biotech in NC – Annual Economic Impact
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THE NORTH CAROLINA BIOTECHNOLOGY CENTER
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
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To provide long-term economic and societal benefits to North Carolina through support of biotech research, business, education and strategic policy statewide.
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Mission
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• State-funded, private, non-profit corporation
• Portfolio of programs – Research
– Business
– Education
– Economic Development
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – What We Do
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
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• Grant funding for:
– New research ideas
– Build capacity – equipment/faculty
– University/Company research projects
• $98 million granted
• $4 to $70 leveraged
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Research Support
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
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Company Creation and Growth: NCBiotech Loan Program
• $50K - $250K low interest loans • ROI = $117 per $1 loaned
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NORTH CAROLINA BIOTECHNOLOGY CENTER
Notable Recent Successes
$96 million acquisition
$25 million IPO
BioKier $1.7 million seed financing
Up to $1.6 million grant
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Advanced Liquid Logic Microfluidics Lab Instruments
• 2003: $50,000 CFG
• Aug-2004: Company founded
• May-2005: $15,000 BDL – 1 employee
• Sep-2005: $72,600 SBR – 3 employees
• Sep-2006: $160,000 SGL – 6 employees
• Jun-2009: $220,500 SGL – 24 employees
• 2011: Launched products for newborn screening, genomic sample prep
• 2011-2013: NCBiotech VC events in Palo Alto, Boston, NYC
• Aug-2012 : $100,000 IFP
• Jul-2013 : $96M acquisition by Illumina – 80 employees
– All loans repaid in full + interest and warrants
– >$50 million follow-on funding before acquisition
• Introductions to bankers and investors, NCBIP, Library, Jobs Board, NCBiotech Partnering 2011-2013, Corporate Communications
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Heat Biologics Cell-based Cancer Immunotherapy
• 2008: Company founded in FL
• Aug-2011: Recruited to NC
• 2011-2012: Assistance with investor pitch
• 2011-2012: NCBiotech VC events in Palo Alto, Boston
• Nov-2011: $225,000 SGL - 2 NC employees – Repaid in full with interest + warrants
• Apr-2012: Industrial Internship Program
• Apr-2013: $5 million VC round
• Jul-2013: $25 million IPO – NASDAQ:HTBX – 5 NC employees
• Investor introductions, partner introductions, foundation introductions, BATON, Library, Corporate Communications, NCBiotech Partnering 2012, BIO Pavilion
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BioKier “Medicinalize” Gastric Bypass for Diabetes
• Nov-2008: Company founded
• Oct-2010: Emerging Company Preview
• Oct-2010: $250,000 SRL – 2 employees
• Oct-2012: Pitch Scrub
• Nov-2012: SEBIO Presentation
• Apr-2013: Southeast Venture Philanthropy Summit
• May-2013: $250,000 SGL – 3.5 employees
• Jul-2013: $1.7 million Broadview Ventures, AHA
• Investor introductions, NCBIP, Corporate Communications, Library, NCBiotech Partnering 2011-2013, LSBDP, Biotech Forums
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Eboo Pharmaceuticals Opioid Modulators for CNS Diseases
• Feb-2012: Company founded
• May-2012: $30,000 CIL – 2 NC employees
• Jun-2012: Introduction to Biogen IDEC
• Jul-2012: SBIR letter of support, recommended MJFF
• Oct-2012: Introductions to CEO candidates
• Nov-2012: Advice on business plan, investor pitch
• Dec-2012: Emerging Company Preview
• Feb-2013: Facilitated meeting with Eli Lilly
• Apr-2013: Southeast Venture Philanthropy Summit
• Jun-2013: Up to $1.6M grant Michael J. Fox Foundation
• BATON, Corporate Communications, Library
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Products, Companies and Jobs
Education, Networking and Other Programs
Statewide Econ Devel
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Statewide Offices
– Research Triangle Park – Eastern (Greenville) – Southeastern
(Wilmington)
– Western (Asheville) – Greater Charlotte – Piedmont Triad
(Winston-Salem)
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
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Since July 2010 • 21 projects • 1,754 employees
Ripple effects: • 7,803 total jobs • $490 million in payroll • $59 million in state and
local revenues • $2.0B in economic activity
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development
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• BIO 2004 in San Francisco – Chiron
• 2006: project announced • 2009: plant opens • 2012: production begins • 2012: $36M expansion • 2013: $60M expansion • Today: >$1B invested, 700
employees, will grow to 1000
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development Novartis Vaccines
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• Early 2010: introduced by Canadian Consulate
• Mid 2010: DARPA, ARE
• Late 2010: construction begins
• Mid 2012: 10M flu doses in one month
• 2013: Acquired by Mitsubsihi in a $357M deal
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development Medicago
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• 2011: Sequenom (molecular diagnostics) – 242 jobs, $19M investment
• 2012: Aerocrine (asthma diagnostics) – 45 jobs
• 2013: bioMerieux: (in vitro diagnostics) – 44 jobs, $44M investment
• 2013: Syngenta (agricultural biotech) – 150 jobs, $94M investment
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Economic Development Recent Announcements
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
NCBiotech – Programs
Ideas
Research Support
Company Creation and Growth
Statewide Econ Devel
Products, Companies and Jobs
Education, Networking and Other Programs
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• 1900+ teachers trained
• 50,000 students reached each year
• $7M in grants for lab equipment & new courses
• 8,000+ BioWork manuals distributed to colleges
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Workforce and Education
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• Industry-driven biopharma manufacturing training and education
• Emerging and existing labor
• BTEC
– 82,500 SF; $60M
– $12.5M equipment
– cGMP pilot plant
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Biomanufacturing Workforce NCBIOIMPACT
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• High-profile conferences
• Hamner Conference Center – 30,000 guests annually
• Networking groups – More than 3,000 attendees
• Biotech Library
• NCBiotech Job Network
• And much more
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Networking and Community
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N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Looking Ahead
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Supportive Ecosystem
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• Place – 3 major research universities in a 30 mile radius – Ecosystem of supportive organizations, risk capital,
entrepreneurial culture
• People – Collaboration among visionary business, academia, gov’t leaders – Attract and retain scientific and business talent
• Programs – Company creation, attraction, retention, expansion – Innovative workforce development programs
• Patience – North Carolina Biotechnology Center: 30 years – Research Triangle Park: 50+ years
N O R T H C A R O L I N A B I O T E C H N O L O G Y C E N T E R
Life Sciences in North Carolina
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Thank You
Mark Lombard Program Director, Bioscience Industrial Development North Carolina Biotechnology Center