Manifestasi klinis

• HELLP syndrome is a life-threatening liver disorder thought to be a type of severe preeclampsia. It is characterized by Hemolysis (destruction of red blood cells), Elevated Liver enzymes (which indicate liver damage), and Low PlateletP count.

• Part 1 of 8: Overview• What Is HELLP Syndrome? • HELLP syndrome is an extremely dangerous condition that can develop in pregnant women. It

includes:• hemolysis • EL: elevated liver enzymes• LP: a low platelet count• Hemolysis refers to a breakdown of red blood cells. Specifically, red blood cells get broken down

earlier than normal. Hemolysis can lead to anemia, a condition in which your blood does not have enough oxygen to supply your body.

• Elevated liver enzymes indicate that your liver is functioning poorly. When liver cells are inflamed or injured, they leak abnormally high amounts of certain chemicals, including enzymes, into your blood.

• Platelets are part of the blood that helps it clot. When they are low, you are at risk for excess bleeding.

• HELLP syndrome usually occurs in the last trimester of pregnancy, before the 37th week. It is a major health concern because it can be fatal to both mother and unborn baby. Prompt treatment and delivery of the baby are generally required for the best outcome. However, about a third of HELLP cases occur after the baby is born in the first week after delivery (Padden, 1999).

• The syndrome’s cause is unknown. Some experts believe it is related to preeclampsia, another pregnancy complication, which causes high blood pressure. There are certain factors that can also increase your chance of developing HELLP syndrome.