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    Management ofthe Apical Third

    The greatest enemy of truth is

    very often not the deliberate,

    contrived and dishonest, but themyth persistent, persuasive, and

    unrealistic.

    We enjoy the comfort of opinion

    without the discomfort of

    thought. John F. Kennedy

    How We Manage

    the Apical Third

    Does it matter?

    Apical Third Histology Historical Concepts

    The CDJ as a dividing line is

    imaginary (Coolidge, 29) Canals should be filled to the CDJ

    (Skillen, 30)

    Canals should be slightly overfilled

    (Blayney, 27)

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    Apical Third Anatomy

    Classic Concept

    Kuttler 55

    Reality

    Dummer 84; Ainamo & Le 68

    Madsen et al 00; Meder et al 09

    Kuttler JADA 1955

    (A myth?)

    Apical Morphology of Maxillary Molars

    Using Microcomputerized Tomography

    Meder-Cowherd L, Williamson A, Johnson W

    In Preparation for Publication, J Endod 2010

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    Materials and Methods

    Shape of apical canal anatomy determined

    Generated micro-computerized 3-D images Analyzed maxillary molar palatal roots

    Selected images giving best view of apical canal

    Analyzed by trained and blinded evaluators

    Determined shape of apical canal anatomy

    Categorized into configuration groups

    Results

    Apical anatomy highly variable

    Several shapes of apical constriction

    Parallel 35%

    Single 18%

    Tapering (Classic) 15%

    Flaring 18%

    Delta 12%

    Frequent deviation of foramen from apex

    Anatomy of Structures in the

    Apical Region of the CanalA Histologic Evaluation

    R. Madsen

    L. Baldassari-Cruz

    R. Walton(Abstract) J Endod 2000

    Materials and Methods

    Teeth and apical tissues removed from cadavers

    Histologically prepared

    Longitudinal sections to include apical 1/3 of canal

    Determined were:

    Location of apical foramen, apical constriction

    Anatomy of apical constriction

    Relationship of CDJ with apical constriction

    Comparison with Kuttlers findings and diagram

    Results Apical Constriction

    Frequently not present

    When present, shape and canal level variable

    Cemento-Dentinal Junction Levels highly variable

    Difficult to interpret

    No specimen matched Kuttlers diagram

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    Multiconstricted Flared

    Apical anatomy often altered because of

    apical pathosis and root resorptionIn Summary:

    Kuttlers concept diagram likely does not occur

    When present, the apical constriction is highly

    variable

    Frequently, there is no constriction

    There is no clinical technique to evaluate presence

    of constriction or shape of apical anatomy

    The apical constriction should not be used as a

    landmark for C&S or obturation

    Apical Canal Anatomy

    The apical few millimeters is variable inshape in cross-section

    Many apical canals are flattened(ribbon-shaped)

    May be multiple foramina

    Frequent deviation from apex

    Gani & Visvisian JOE 1999

    Wu et al OOOOE 2000

    Soma et al IEJ 2008

    Martos et al IEJ 2009 Ganni and Visvisian 99; Wu 00

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    Apical Canal Structure Marked variations

    Accessory canals, resorptions, repair,

    pulp stones, irregular secondary

    dentin

    Cementum-like tissue on canal walls

    Mjr et al IEJ, 2001

    Apical Third Histology

    Classic Concept

    Reality

    Aberrations in the Apical Third

    Frequency

    Can they be debrided?Can they be obturated?

    Does it matter?

    Lateral Canals

    Frequency

    Can they be debrided?Can they be obturated?

    Does it matter?

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    Frequency and Location

    Frequency high

    Most in posterior teeth

    Predominance in apical 1/3

    Degerness and Bowles J Endod 2008

    Apical Delta

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    Can Lateral Canals be

    Obturated in the Apical Third?

    Canals prepared thenobturated with Schildertechnique

    Roots were cleaned

    Very few lateral canals filledwith gp and/or sealer

    Venturi et al IEJ 36:54, 2003

    Are Lateral Canals and Apical

    Ramifications Debrided and Filled?

    Apparently not

    Teeth with RCT extracted

    Roots prepared histologically

    LCs and ARs examined for tissue, obturating

    materials and bacteria

    Results: LCs and ARs not debrided and

    seldom contained obturating material

    Ricucci, Siqueira. J Endod 36: 1, 2010

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    Does It Matter If Lateral Canals are

    Debrided and Obturated?

    Apparently not

    Block sections of apical regions in root-filledteeth were examined in cadaver jaws

    All roots had lateral canals

    No lateral canals contained obturatingmaterial

    No relationship was detected betweenunfilled lateral canals and the status ofinflammation at the periapex

    Barthel, Zimmer, Trope. J Endod 30:75, 2004

    Intracanal Isthmi

    FrequencyCan they be debrided?

    Can they be obturated?

    Does it matter?

    Apical Patency

    What is it?

    What is the technique based upon? What are the advantages?

    What are the disadvantages?

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    How will small patency files behave?

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    Patency File and Apical

    Transportation

    #s 10, 15, 20 and 25 patency files Precurved SS and NiTi hand files

    Files used sequentially

    Transportation seen with each file

    size

    Goldberg & Massone J Endod 28:510, 2002

    Effect of Maintaining Apical Patency

    on Canal Transportation

    Compared different preparation techniques

    Lightspeed rotary with and without patency files Balanced force hand with and without patency

    Results:

    All techniques produced transportation

    No difference between groups

    Tsesis et al IEJ 2008

    Apical Patency: Other considerations?

    Post-treatment pain? No effect

    Arias et al J Endod 2009

    Success rate? Not determined

    Tissue damage?

    Not determined, however

    Updated recommendations for managing

    the care of patients receiving oral

    bisphosphonate therapy. JADA 2009

    For endodontic procedures:

    Manipulation beyond the apex is not

    recommended

    Apical Patency in Summary:

    Has no biological rationale

    Likely

    does not accomplish the stated objectives

    damages periapical tissues

    does not improve outcomes

    Has no effect on postreatment pain

    Aspects of Apical Third

    Preparation

    Apical Clearing

    Size of Preparation

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    Does Increased Enlargement Reduce

    Bacteria and Improve Debridement?

    Yes Tan & Messer. JOE 2002

    Card et al. JOE 2002

    Usman et al. JOE 2004

    Baugh & Wallace. JOE 2005

    Heish et al. IEJ 2007

    No (when initially to a larger size) Coldero & Saunders. IEJ 2002

    Bacteria in the apical third

    Before

    Oval Canal Necrotic

    Debris

    After

    Round Canal Clean and

    Ready for

    Obturation

    Apical Clearing

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    Effectiveness of Apical

    Clearing: Histologic and

    Morphologic Evaluation

    Parris J, Wilcox L, Walton R J Endod 20:219, 1994

    Apical Clearing Procedure

    Final apical preparation (enlargement)

    Irrigant present in canal

    Files 3-4 sizes larger than MAF rotated at WL

    Canal irrigated

    Canal dried with paper points

    Final apical reaming (Dry Reaming)

    Largest file rotated at WL

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    Possible Advantages of Apical

    Clearing

    Maximize debridement

    Deeper penetration of irrigating

    needle/solution

    Increase size of apical preparation

    Improved obturation

    Objectives

    Debris removal and walls planed

    Apical transportation

    Compare effectiveness of step-backwithout apical clearing vs. step-

    back with apical clearing for:

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    Conclusions

    Apical clearing resulted in better

    debridement

    Apical transportation was found in

    both groups; more in the apically

    cleared group

    Why is there minimal transportation?

    What About the Smear Layer?

    Studies generally favor removal

    NaOCl alternated with EDTA best

    Deep needle penetration

    Special irrigating devices?

    Apical third less predictable removal

    Messer

    Uroz-Torres et al. J Endod, 2010

    Violich, Chandler. Int Endod J, 2010

    What About Apical Preparation Size?

    R Madsen

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    Root Canal TreatmentRoot Canal Treatment

    Looks Good?Looks Good?

    Length OKLength OK

    Shape OKShape OK

    Why did it fail?Why did it fail?

    LetLets extract and sections extract and section------

    Courtesy Dr S Senia

    Mesial root - 1 mm from apex

    necrotic tissue and debris

    Mesial root - 2 mm from Apex Distal Root - Foramen

    Poor obturationPoor obturation

    Distal Root - 1 mm from Apex

    Necrotic tissue and debris

    Canal notCanal not

    instrumented to theinstrumented to the

    correct diametercorrect diameter

    Distal Root - 3 mm from Apex

    Necrotic Tissue and Debris

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    Nair R. In: Pathways to the Pulp 2006

    Working Length

    ConsiderationsPrognosis

    Periapical Response

    Post-treatment Symptoms

    Systemic Impact

    Considerations

    PrognosisPrognosis

    Periapical Response

    Post-treatment Symptoms

    Systemic Impact

    PrognosisExtrusion of

    Obturating Material

    An irritantRelated to decreased

    success Nair R. Pathways of the Pulp,

    2006

    Torabinejad & Siggurdson.

    Endodontics: Principles and

    Practice 2009

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    Determining Optimal Obturation

    Length: A Meta-analysis of Literature

    Short of the radiographic apex

    had better success than long

    Preferable to err on the short side

    than be long (uncertain about

    sealer extrusion only)

    Schaeffer, White, Walton. J Endod 2005

    Evid Based Dent 2005

    Prognosis

    Long-term Studies Show: Optimal result: end preparation and

    obturation within radiographic apex

    Too short, success rate drops

    Beyond apex, an even poorer result

    Gutmann & Witherspoon, Pathways to

    the Pulp, 8th ed. 2002

    Prognosis

    Success rate of endodontic treatment of teeth with

    vital and nonvital pulps. A meta-analysis

    No difference between vital and non-vital pulps

    Failure rate greater with a lesion present

    Success much lower with obturation overextension than

    with flush or underextension

    Conclusion: The root canal should be filled to within

    2mm of the radiographic apex.

    Kojima K et al. OOOOE 97: 95, 2004

    Considerations

    Prognosis

    PeriapicalPeriapical ResponseResponsePost-treatment Symptoms

    Systemic Impact

    Tissue Injury and Inflammation

    from:

    Instruments

    Irrigants

    Medicaments

    Obturating Materials

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    Termination of Preparation and

    Obturation

    Short of the radiographic apex

    Short of the apical foramen Review: Ricucci, Langeland, Int Endo J, 1998

    Termination of Preparation and

    Obturation

    Vital pulp: 1-3 mm short Necrotic pulp: 0-2 mm short

    Wu, Wesselink, Walton OOOOE 2000

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    Techniques of Canal Preparation

    StandardizedFlaring

    Stepback

    Crown-down

    Rotary

    Debridement of the Apical Third

    Hand tends to debride better than

    rotaryApical canals are variable in shape

    Uninstrumented, undebrided areasare common

    Ahlquist et al IEJ, 2001

    Barbizam et al JOE, 2002

    Wu & Wesselink IEJ, 2001

    Rdig et al IEJ, 2002

    Shaping of the Apical Third

    All techniques tend to transport

    Factors (curvature, size, shape) are

    important

    Different instruments and

    techniques cause variability Peters et al J Endod, 2001

    Imura et al J Endod, 2001

    Ahlquist et al Int Endod J, 2001

    Hartmann et al J Endod, 2007

    Moore et al Int Endod J, 2009

    ObturationLength

    Technique

    Cold Lateral

    Warm Vertical

    Other

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    Tissue Reaction to Obturation

    Short of the apex little

    responseBeyond the apex

    Inflammation

    Delayed healing

    Ricucci & Langeland, IEJ, 1998

    Guttmann & Witherspoon, 2002

    Extrusion of Debris

    Compared NiTi rotary (Lightspeed & ProFile

    .04) and stainless steel hand (step-back &balanced force)

    Determined amount of debris extrusion

    All techniques produced apical debris

    Overall, NiTi rotary extruded the least

    Reddy S & Hicks L. JOE, 1998

    Considerations

    Prognosis

    Periapical Response

    PostPost--treatment Symptomstreatment Symptoms

    Systemic Impact

    Post-Canal Preparation Symptoms

    Canal preparation with either SS hand or NiTi

    rotary

    Determined pain levels and pain incidence

    No difference in the groups

    Aqrabawi J et al. J Dent 2006

    Post-Obturation Symptoms

    48% reported symptoms after

    obturation

    10% or less significant symptoms Overfill (no lesion) more pain

    Harrison et al. JOE, 1983

    Considerations

    Prognosis

    Periradicular Response

    Post-treatment Symptoms

    Systemic ImpactSystemic Impact

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    Systemic Considerations

    Oral Microbes and Disease

    Bacteremia

    Inducing Bacteremia

    Factors that produce

    bacteremia

    Necrosis

    Over-instrumentation

    Impact

    Bacterial Extension

    Pulp Necrosis

    Apical Foramen

    Short Close

    Beyond

    Bender et al, Oral Surg, 60

    Baumgartner et al, JOE, 76

    Overinstrumentation and

    Bacteremia

    Periradicular Contamination Gutierrez et al., 1999

    Intracanal Bacteria in Blood Debelian and Tronstad, 1998

    Ayub et al IEJ 2007

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    Updated recommendations for managing

    the care of patients receiving oral

    bisphosphonate therapy. JADA 2009

    For endodontic procedures:

    Manipulation beyond the apex is not

    recommended

    In Conclusion

    Apical canal anatomy and histology are

    variable and indeterminable, clinically

    Instruments, materials and chemicals

    should be confined to the canal

    Conclusions (continued)

    Lengths should be 1-3 mm short of the apex

    Aberrations are inconsistently debrided

    Debris in the apical canal preparation should be

    reduced before obturation

    Apical canal preparation should be at least #40

    There is no superior instrumentation technique

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    Periapical Tissue Injury and

    Inflammation Occurs from:

    Instruments

    Irrigants

    Medicaments

    Obturating Materials

    Termination of Preparation and

    Obturation

    Vital pulp: 1-3 mm short

    Necrotic pulp: 0-2 mm short

    Termination of Preparation and

    Obturation

    Short of the radiographic apex

    Short of the apical foramen

    Bacterial Extrusion Beyond the

    Apex Will Produce:

    Periapical inflammation

    And May Produce:

    Systemic disease

    FinallyWe need more definitive

    information based on:

    Scientific data

    Evidence-based research

    Outcomes assessment

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    Good clinical decisions require

    scientific accuracy to avoid bias

    Clinical significance is the

    consideration of risk vs. benefit

    Important outcomes (success) of

    therapy are measured by a

    combination of evidence-based

    criteria, clinical judgment and

    common sense.