Male reproductive gland
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Transcript of Male reproductive gland
MALE REPRODUCTIVE GLAND
By J9
TESTES Located in the scrotum Secrete hormone known as androgen;
most important of which is testosterone Have an exocrine part, Seminiferous
tubules (tightly coiled) and endocrine part, intersitial or Leydig cells (clusters)
Leydig cells Synthesise and secrete testosterone Located in the interstitial tissue between
the convuluted seminiferous tubules Occurs in clusters, which are variable in
size and richly supplied by capillaries Its cytoplasm is strongly acidophilic and
finely granular The nucleus is large, round and often
located eccentric in the cell
General effects of the testosteroneAnabolic
Growth of muscle mass and strength
Increased bone density and strength
Linear growthBone maturation
Androgenic (Virilizing)Maturation of sex organs (part. Penis)
Formation of scrotum in the fetus
Deepening of voice (sec. sex charac.)
Growth of beard and axillary hair (sec. sex charac.)
...cont. testosterone Testosterone increases sharply at
puberty Essential for the production of sperm Production of testosterone is controlled
by the release of luteinizing hormone (LH)
Hypothalamus GnRH Pituitary
LHTestesTestosterone
Sertoli cells ‘nurse’ cell of the testes Part of the seminiferous tubule Activated by follicle-stimulating
hormone and has FSH-receptor on its membranes.
Estradiol and Inhibin – hormone secreted
EstradiolPrevent apoptosis (death of cells) of
germ cellsInhibin
Inhibit production of FSH
Arrows shows the location of the leydig cells
1 Lumen of Tubulus seminiferus contortus2 spermatids3 spermatocytes4 spermatogonia5 Sertoli cell6 Myofibroblasts7 Leydig cells8 capillaries
TESTIS