Lysteria monocytogenes and Shigella flexerni use actin based motility to spread to other cells...
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![Page 1: Lysteria monocytogenes and Shigella flexerni use actin based motility to spread to other cells -Cause diarrhea, vomiting, fever, and can lead to menningitis.](https://reader035.fdocuments.us/reader035/viewer/2022062805/5697bfef1a28abf838cb9f0e/html5/thumbnails/1.jpg)
Lysteria monocytogenes and Shigella flexerni use actin based motility to spread to other cells
-Cause diarrhea, vomiting, fever, and can lead to menningitis and spontaneous abortions
-Causes death in immunocompromised people (children, elderly, AIDS patients)
-Produce a protein that encourages production of actin filaments at the cell surface
-Propels bacteria through the cytoplasm (Comet tails)
-Rams into the cytoplasmic membrane and pushes through into the next cell
-Avoids much of the immune system
Movies: http://cmgm.stanford.edu/theriot/movies.htm#Hits
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Close up of single bacterium (Vibrio) Bacteria (Vibrio) glowing on a petri dish
Vibrio fischeri and its host, the bobtail squid
Light organs on squid belly useVibrio to reflect the same wavelength of light as the moon, hiding their shadow from preditors
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Pineapple fish-lower jaw contains a photophore whereVibrio reside. The bioluminescence attracts zooplankton.-glows orange during the day, blue green by night.
Vibrio and its host, the Pineapple fish
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The angler fish uses bioluminescent bacteria to attract prey
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http://subrealism.blogspot.com/2009_04_01_archive.html
Quorum sensing in Vibrio
Bioluminescence is very expensive so the cells only want to bioluminesce when other cells are around. No point if they’re not in the squid light organ.
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The amazing Myxococcus xanthus
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Myxococcus xanthus cell
A Myxococcus swarm
Myxococcus
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Aggregation and “rippling” of Myxococcus
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Dictyostellum discoideum-slime mold fruiting bodies (amoeba)
Myxococcus fruiting bodies
Fruiting bodies
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Dictyostellum discoideum-slime mold fruiting bodies (amoeba)
Slime mold fruiting bodies
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Bacillus fruiting body. A sporulation gene was fused with lacZand the cells were plated on medium containing x-gal. You can see the where sporulation occurs by the dark blue color
Branda S S et al. PNAS 2001;98:11621-11626
Bacillus fruiting bodies
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Movies
http://www.youtube.com/watch?v=O1jPzhz1Qyc
http://www.youtube.com/watch?v=bkVhLJLG7ug&feature=related
http://www.youtube.com/watch?v=oVGEFGzS7Wo&feature=related
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Healthy ant
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Zombie ants
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