flow+Active mesh nebuliser

for every stage of disease:

H O M E C A R E

P n e u m o l o g y

N e o n a t o l o g y

A n a e s t h e s i a

INTENSIVE CARE VENTILATION

S l e e p D i a g n o s t i c s

S e r v i c e

P a t i e n t S u p p o r t

flow+ and pressure+LÖWENSTEIN MEDICAL

Effective and directly to the site of action:breath-synchronized, low-loss, hygiene-optimized

LÖWENSTEIN MEDICAL m-neb works:

Bronchodilation, minimizing hypercapnia, or improving the man-agement of secretions – those are common indications for direct drug delivery to the site of action in the lungs. If the medication is to reliably pass into the bloodstream from there, the aerosol droplets must be smaller than 5 micrometres. The droplet size of conventional medication nebulisers is much larger, with a diameter of at least 8 micrometres. This method has been proven to only transfer 1 to 3% of an active substance to the blood. Accordingly, pneumatic nebulisation is highly ineffective.

C.J. Harvey, M.J. O‘Doherty, C.J. Page, S.H.L. Thomas, T.O. Nunan, D.F.

Treacher. Comparison of jet and ultrasonic nebuliser pulmonary aerosol de-

position during mechanical ventilation. Eur Respir J 1997; 10: 905–909. DOI:

10.1183/09031936.97.10040905

LÖWENSTEIN MEDICAL m-neb offers the ideal droplet size for maximum effectiveness:

High-frequency ultrasonic pulses transport small volumes of liquid medication through a special membrane. Its micro-structure chan-nels the droplet formation and guarantees a droplet size of less than 4 micrometres in diameter. The drug is transported gently without heating it up. The small droplets pass through the bron-chial tree to the pulmonary alveoli for direct deposition at the site of action. Maximum efficiency

with ideal droplet size

Wenn kleine Dinge große Wirkung zeigen!

Small devices - major impact!

LÖWENSTEIN MEDICAL

LÖWENSTEIN MEDICAL m-neb - inspiration de-tection for optimal medication deposition:

The normal physiological ratio of inspiration and expiration is 1:1.7. Since conventional ultrasonic nebulisers cannot detect inspiration and expiration, they dispense a continuous aerosol flow. Even if the droplet size is right, less than two fifths of an aerosolized medica-tion is therefore delivered to the lungs with the previous gener-ation of devices. The bulk of the medication does not even reach the bronchial tubes, but is returned to the surrounding air with exhalation. LÖWENSTEIN MEDICAL m-neb flow+ solves this problem: It is the first compact drug nebuliser to feature an inspira-tory flow trigger. The medication reaches the pulmonary alveoli practically without loss.

Inspiration Drug nebulisation

active

Expiration Drug nebulisation

inactive

LÖWENSTEIN MEDICAL m-neb offers optimal hygiene and prevents return flow:

Ventilator-associated pneumonia is the most common infection in intensive-care medicine and also has the highest mortality rate. Extensive hygiene is the best prevention. The sterile disposable components of LÖWENSTEIN MEDICAL m-neb avoid cross-con-tamination and prevent performance losses caused by reprocess-ing. The device automatically switches off when the medication chamber is empty. The aspiration of contaminated secretions into the empty medication chamber is impossible.

Wenn kleine Dinge große Wirkung zeigen!

Item no.: Designation Item no.: Designation

153053005LM m-neb Flow+ incl. 2 nebuliser, 2 T-pieces, 1 mains adapter, 2 trigger tubes, 1 device holder, 2 adapter, 1 USB connecting cable

153053011 basic device: LM m-neb Flow+

153053000LM m-neb Pressure+ incl. 2 nebuliser, 2 T-pieces, 1 USB connecting cable, 1 mains adapter, 1 device holder

153053010 basic device: LM m-neb Pressure+

153053111 LM m-neb mouthpiece 153053108 LM m-neb mains adapter

153053109 LM m-neb device holder for Pressure+ 153053101LM m-neb nebuliser with approach for intubated patients (T-piece) for Pressure+ and Flow+

153053110 LM m-neb device holder for Flow+ 153053102 LM m-neb nebuliser with mouthpiece for Pressure+

153053104 LM m-neb USB connecting cable for Pressure+ and Flow+ 153053107 LM m-neb adapter for trigger tube, Luerlook

153053106 LM m-neb trigger tube

Löwenstein MedicalArzbacher Straße 80D - 56130 Bad EmsPhone: +49 26 03/96 00 0Fax: +49 26 03/96 00 50www.hul.de

All rights reserved | Subject to technical changes | Images might be different to the original | Rev. 2.0 I p10118en1611

Patients pass through different stages of disease and hospital units on their way to recovery. Whether used for intensive-care ventila-tion, as part of non-invasive ventilation, for respiratory therapy or in a general ward, the LÖWENSTEIN MEDICAL m-neb ultrasonic nebuliser is consistently available for targeted drug administration.

The same nebuliser head can be used throughout the process chain – from intensive-care ventilation to therapeutic applications and home therapy.

...integrated

...in combination with intensive-care ventilator

...in combination with respiratory therapy equipment

...in combination with home ventilator

for every stage of disease:LÖWENSTEIN MEDICAL