Loring B. Rowell. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev. 1974...
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Transcript of Loring B. Rowell. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev. 1974...
Loring B. Rowell
• Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev. 1974
• How Are Blood Flow and Metabolism Matched?", Mayo Clinic, Rochester, MN, January, 1993.
• Cardiac Function in Hyperthermia and Hypoxemia”, Brisbane, Australia, August, 1996.
• Why Do We Require a Second Heart During Exercise? U. of W. Ontario, 2000
• Human Circulation: Regulation during physical stress. Oxford U. Press. 1986
• Human Cardiovascular Control. Oxford. 1993
• Handbook of Physiology: Section 12: Exercise: Regulation and Integration of Multiple Systems. APS. 1996
Academic History
1953 BS Springfield College, Springfield, Mass.Prof. Karpovich
1953 – 56 Science and Math teacher, Littleton High School Littleton/Franconia, N.H.
1962 Ph. D. University of Minnesota Minneapolis, Minn.
A Krogh 1874 – 1949U. of Copenhagen, DK
Ancel Keys F. Grande
U. Minnesota (LBR as student 1956-62)
Harvard U. England (Lovatt Evans)
Spain (beri beri research)
A Krogh 1874 – 1949U. of Copenhagen, DK
P.O. AstrandB. Saltin
E. AsmussenE. H-ChristensenMaurius Nielsen
B. SaltinB. NielsenF. Bonde-Petersen
Sweden
Krogh Institute(LBR sabbatical 1978-79)
A. KeysJ.T. ShepherdE. WoodY. Wang
Mayo Clinic(LBR 1960-1)
M. Visscher
H.L. TaylorA. KeysF. GrandeY. Wang
U. Minnesota(LBR 1956-62)
L. J. HendersonAncel Keys
H.L. Taylor
Harvard U
Cardiac output and its distribution among the organ
vasculatures
heart level, 5 Torr
foot level, 100 Torr
Central
Splanchnic, renal
Cutaneous
30 60 90 min
Heating Heating
Flow:volume interaction
Heating Heating
Stroke volume and the interaction between the heart and the peripheral vasculature
30 60 90
Time (min)
Right atrial pressure
Cardiac output(venous return)
Right atrial pressure
Cardiac output(venous return)
0
“Venous return curve” “Vascular function curve”
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+
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Gravity, the muscle pump,and reflex control
Overall control mechanisms: The exercise stimulus
Muscle chemoreflex: Zuntz 1889 , Wyss, Sheriff, O’Leary, Scher
University of Minnesota
University of WashingtonMedicine (Cardiology)
1962 - 70Physiology and Biophysics
(1970 - )
H.D. Patton, W. CrillE. MasoroG. L. BrengelmannA. ScherA.C. BrownO.A. SmithM. BinderJ. W. Woodbury
R. A. BruceJ. R. BlackmonJ.W. Kennedy
E. Strandness (Surg)W. Volwiler (GI)J. Short (Derm)J. Olerud (Derm)
Symposium on Alpine Crystallography