Leslie A. Morrison, M.D.

Department of Neurology MSC10 5620 Office of the Chancellor MSC09 5300

1 UNIVERSITY OF NEW MEXICO 505-272-5849 (OFFICE)

Licensure and Certification: New Mexico Medical Board 1992 American Board of Psychiatry and Neurology (ABPN) Certification 1993 Voluntary Recertification ABPN 2003 Education, Postgraduate Training: Johns Hopkins Medical Institutions, Baltimore, MD, Child Neurology 1989-1992 Johns Hopkins Medical Institutions, Baltimore, MD, Pediatrics 1987-1989 Medical Doctorate: University of New Mexico School of Medicine, Albuquerque, NM 1987 Baccalaureate Degree: UNM Bachelor of Science, Physical Therapy 1978 Professional Experience: Vice Chancellor for Academic Affairs UNM HSC 2012- Executive Director for Student and Faculty Affairs UNM HSC 2011-2012 Associate Dean, Academic Affairs, UNM SOM 2009-2012 Assistant Dean, Academic Affairs 2005-2009 Vice Chair Neurology, UNM 2003-2009 Neurology Chief of Clinical Operations 1998-2003 Division Chief, Child Neurology 1997-2010 Faculty and Staff Appointments: Professor, Neurology and Pediatrics 2006- Associate Professor, Neurology and Pediatrics 2000-2006 Assistant Professor, Neurology and Pediatrics 1994-2000 Staff Physician, Letters of Academic Title Neurology and Pediatrics 1992-1994 Leadership: Executive Leadership in Academic Medicine (ELAM) Drexel University 2008-2009

ELAM Alumnae Development Committee 2009-2012 ELAM Alumnae Program Steering Committee ELAM Selection Committee 2010-

Neurology Leadership Course, Washington, DC 2008 Government Experience: Neurology on the Hill, Washington, DC 2007, 2008 Stem Cell press conference, State NM, Governor Richardson 2008 Medicaid forum, Senator Jeff Bingaman 2005 Child Neurology Society and Foundation, Capitol Hill 2003-2005 Memberships and Leadership in Professional Societies: UNM La Tierra Sagrada Society Member 2009-

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Board of Directors 2011- Grant Review Subcommittee 2011- Chair 2012- Association of American Medical Colleges Group on Faculty Affairs Steering Committee 2011-2012 Conference Planning Subcommittee 2011- Group on Women in Medicine and Science Designee 2009- National Initiative on Gender, Culture and Leadership in Medicine

(C-change) Learning Action Network member 2009-2011 Internal Working Group Faculty Development 2008- Quality Standards Subcommittee, American Academy Neurology, 2005-2011

Child Neurology representative American Academy of Neurology, member in good standing 2004- Section of Child Neurology 2011- Nominee Vice Chair 2011 Professors of Child Neurology (PCN) 1999-2010

Elected councilor PCN 2002-2004 Association of University Professors of Neurology 1998- Child Neurology Society active member 1990-

CNS Executive Board, Councilor from the West, 2 year term 2006-2008 Member, Practice Committee 2001-2011

United Council of Neurologic Subspecialties Board of Directors 2004-2009 Chair 2005-2009

Secretary-Treasurer UCNS 2005 Child Neurology Foundation, Director 2002-2006 Chair Bylaws Committee, substantial revision 2003-2006

Regional Seminar, Pediatric Epilepsy for Primary Care 2003 Society of Clinical Neurologists, councilor 2000-2003 American Board of Psychiatry and Neurology examiner 1996-2005 Child Neurology Recertification committee 2001-2005 Other Extramural Activities: Grant Reviewer

NIH Career Scientist Awards 2010 NIH Wellstone 2010 MDA 2004, 2008, 2010- National Armed Forces, Duchenne 2004 NINDS Pilot Therapeutic Trials Network 2005

Editorial board Journal of Child Neurology 2003- Editorial board Pediatric Neurology 2002-2011 Neurology Ad hoc reviewer 2002- Muscular Dystrophy Association Advisor, Neuromuscular REACH project 2009-2011 (Research through Enhanced Technology Architecture for Comprehensive Healthcare)

Transitions Committee, Muscular Dystrophy Association 2008-2009 QUEST, Doctor Visits for Duchenne Muscular Dystrophy 2008 QUEST Sorting Out Oculopharyngeal Muscular Dystrophy 2004 Chat Host, Mitochondrial Myopathies Ask the Experts 2004-2008 MDA Telethon NM: OPMD, Becker MD, Pompe Disease 2005-2007 Camp physician 2000

Standard of Care subcommittee of the International Coordinating Council, Spinal Muscular Atrophy 2005

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Transverse Myelitis Association Medical national Advisory Board 2002-2004 Angioma Alliance

Scientific Advisory Board 2004- Patient Education meetings 2006- Pathobiology of CCM 2006-2012

Children’s Miracle Network Telethon, television interview 2004 Peer Reviewed Publications: Submitted: Hart BL, Taheri S, Rosenberg GA, Morrison LA. Dynamic Contrast-Enhanced MRI Evaluation of Cerebral Cavernous Malformations, submitted Translational Stroke Research November 2012, under revision for resubmission (February 2013) Published Manuscripts: Akers A, Ball KL, Clancy M, Comi A, Faughnan ME, Gopal-Srivastava R, Jacobs TP, Kim H, Krishcher J, Maruchuk DA, McColloch CE, Morrison L, Moses M, Moy CS, Pawlikowska L, Young WL. Brain Vascular malformation consortium: Overview, Progress and Future Directions. Journal of Rare Disorders. Accepted February 21, 2013. Brashear A, Mink JW, Hill DF, Boggs N, McCall WV, Stacy MA, Snively B, Light LS, Sweadner KJ, Ozelius LJ, Morrison L. ATP1A3 mutations in infants: a new rapid-onset dystonia--Parkinsonism phenotype characterized by motor delay and ataxia.Dev Med Child Neurol. 2012 Nov; 54(11):1065-7.1469-8749.2012.04421.x. Epub 2012 Aug 28.PMID:22924536 Bunton SA, Corrice AM, Pollart SM, Novielli KD, Williams VN, Morrison LA, Mylona E, Fox S. Predictors of Workplace Satisfaction for U.S. Medical School Faculty in an Era of Change and Challenge, Academic Medicine, Acad Med. 2012 May;87(5):574-81. Allen RC, Zimmerman MB, Watterberg EA, Morrison LA, Carter KD. Primary bilateral silicone frontalis suspension for good levator function ptosis in oculopharyngeal muscular dystrophy Br J Ophthalmol 2012 Jun;96(6):841-5. Epub 2012 Apr 4. PMID: 22493036 Wang CH, Dowling JJ, North K, Schroth M,Sejersen T,Shapiro F, Bellini J, Weiss H, Guillet M, Amburgey K, Apkon S, Bertini E, Bonnemann C, Clarke N, Connolly AM, Estournet-Mathiaud B, Fitzgerald D, Florence JM, Gee R,Giannetti JG, Glanzman A, Hofmeister B,Jungbluth H, Koumbourlis AC, Laing NG, Main M, Morrison LA, Munns C,Rose K, Schuler PM, Sewry C, Storhaug K, Vainzof M, Yuan N. Consensus Statement on Standard of Care for Congenital Myopathies. J Child Neurol 2012 Mar 27: 363. PMID:22431881 Morrison L, Akers A: Cerebral Cavernous Malformation, Familial (May 2011) in: Gene Reviews at Gene Tests: Medical Genetics Information Resource [database online]. Copyright, University of Washington, Seattle, 1997-2010. Available at http://www.genetests.org. Morrison L, Dystrophinopathies. Handbook of Clinical Neurology. 2011;101:11-39. Palmer PM, Neel AT, Sprouls G, Morrison L. Swallow Characteristics in Patients with Oculopharyngeal Muscular Dystrophy. J Speech Lang Hear Res. 2010 Aug 10 (Epub).

Bushby K, Finkel R, Birnkrant DJ, Case LE, Clemens PR, Cripe L, Kaul A, Kinnett K, McDonald C, Pandya S, Poysky J, Shapiro F, Tomezsko J, Constantin C; DMD Care Considerations Working Group. Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care Lancet Neurol. 2010 Feb; 9(2):177-89. Epub 2009 Nov 27.

Ashwal S, Michelson D, Plawner L, Dobyns WB; Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Practice parameter: Evaluation of the child

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with microcephaly (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society.Neurology. 2009 Sep 15;73(11):887-97.

Delgado MR, Hirtz D, Aisen M, Ashwal S, Fehlings DL, McLaughlin J, Morrison LA, Shrader MW, Tilton A, Vargus-Adams J. Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology. 2010 Jan 26;74(4):336-43. Review. Leblanc GG, Golanov E, Awad IA, Young WL; Biology of Vascular Malformations of the Brain NINDS Workshop Collaborators. Biology of vascular malformations of the brain. Stroke. 2009 Dec; 40(12):e694-702. Epub 2009 Oct 15. Review. Petersen T, Morrison L, Shrader R, Hart B. Familial Versus Sporadic Cavernous Malformations: Differences in Developmental Venous Anomaly Association and Lesion Phenotype. American Journal of Neuroradiology 4-13-09. Allen RC, Jaramillo J, Black R, Sandoval D, Morrison L, Qualls C, Carter KD, Nerad JA. Clinical characterization and blepharoptosis surgery outcomes in Hispanic New Mexicans with oculopharyngeal muscular dystrophy. Ophthal Plast Reconstr Surg. 2009 Mar-Apr;25(2):103-8 Morrison L, Unraveling RYR1 mutations and muscle biopsies, Neurology, 2008 Jan;70 99-100. Al Shahi R, Farrall A, Berg M, Morrison L, Awad I. Hemorrhage from cerebral cavernous malformations: definition and reporting standards. Angioma Alliance Scientific Advisory Board. Stroke 2008 Dec;39(12):3222-30. Précis article below, published on website European Neuromuscular Society, 2007 Wang CH, Finkel RS, Bertini ES, Schroth M, Simonds A, Wong B, Aloysius A, Morrison L, Main M, Crawford TO, Trela A and the Participants of the International Conference on SMA Standard of Care Consensus Statement for Standard of Care in Spinal Muscular Atrophy J Child Neurol 2007 22: 1027-1049. Zlotoff BJ, Bang RH, Padilla RS, Morrison L. Cutaneous angiokeratoma and venous malformations in a Hispanic-American patient with cerebral cavernous malformations. Br J Dermatol. 2007 Jul;157(1):210-2.

Neel AT, Palmer PM, Sprouls G, Morrison L. Tongue strength and speech intelligibility in oculopharyngeal muscular dystrophy. Journal of Medical Speech- Language Pathology 2006, 14, 273-277.

Gasparovic C, Song T, Devier D, Bockholt HJ, Caprihan A, Mullins PG, Posse S, Jung RE, Morrison LA. Use of tissue water as a concentration reference for proton spectroscopic imaging. Magn Reson Med. 2006 Jun;55(6):1219-26.

Kerr D et al (The Transverse Myelitis Consortium Working Group). Proposed Diagnostic Criteria and Nosology of Acute Transverse Myelitis. Neurology, August 2002. Becher M, Morrison L, King M, Davis L, Bear D. Oculopharyngeal muscular dystrophy in Hispanic New Mexicans. JAMA, 2001;296(10):2437-2440. Sahoo T, Johnson EW, Thomas JW, Kuehl PM, Jones TL, Dokken CG, Touchman JW, Gallione CJ, Lee-Lin S, Kosofsky B, Kurth JH, Louis DN, Mettler G, Morrison LA, Gil-Nagel, A, Rich, SS, Zabramski, JM, Boguski, MS. Green, ED, Marchuk, DA. Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations (CCM1). Hum Mol Genet 1999, 8:2325-2333.

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Gunel M, Awad I, Finberg K, Anson J, Steinberg GK, Batjer HH, Kopitnik TA, Morrison LA, Giannotta SL, Nelson-Williams C, Lifton RP. A founder mutation as a cause of cerebral cavernous malformation in Hispanic Americans. New England Journal of Medicine 1996, 334:946-51. Marchuk DA, Gallione C, Morrison LA, Clericuzio CL, Hart BL, Kosofsky BE, Louis DN, Gusella JF, Davis LE, Prenger VL. A locus for cavernous angioma maps to proximal 7q in two families. Genomics 1995;28:311-314. Johnson EW, Iyer LM, Rich SS, Orr HT, Gil-Nagel A, Kurth JH, Zabramski JM, Marchuk DA, Weissenbach J, Clericuzio CL, Davis LE, Hart BL, Gusella JF, Kosofsky BE, Louis DN, Morrison LA, Green ED, Weber JL. Refined localization of the cerebral cavernous malformation gene (CCM1) to a 4-cM interval of chromosome 7q contained in a well-defined YAC contig. Genome Res. 1995 Nov;5(4):368-80. Cornblath DR, Kurland LT, Boylan KB, Morrison L, Radhakrishnan K, Montgomery M. Conjugal amyotrophic lateral sclerosis: Report of a young married couple. Neurology 1993;43:2378-2380. Published or Presented Abstracts and Posters (National):

Baca BA, Hart BL, Kim H, Morrison L. Lesion Burden, Location, and Clinical Characteristics in a Genetically Unique Cohort of Patients with Cerebral Cavernous Malformations, RSNA 11-26-12 Morrison L, Wegele A, Baca B, Cutaneous Features of CCM1-CHM cohort, Angioma Alliance Scientific meeting, Washington DC, Nov 2012 Commitment to Equity: Salary and Beyond: Barrett, Souza, Ku C, Morrison L, Pomeroy C, Washington. Career development and succession planning: A systematic approach. AAMC Nov 5, 2012, San Francisco, CA Part-Time Faculty in Academic Medicine: Pollart S, Morrison L, Corrice A, Bunton S. AAMC Group on Faculty Affairs 2012 Using Data to Spark Innovation: Improving Talent management with Evidence-based Practices. Hostler S, Misfeldt M, Morrison LA, Pollart S, Buckley P, Grigsby RK. AAMC 2011. Using Data to Change the Culture at Three Academic Medical Centers Pololi L, Morrison L, Evans A, Gibbs B.. AAMC 2011 Morrison L, Trief P, Callahan E. The Department Chair as Chief Talent Office: Strategies to Develop Chairs Who Develop Their Faculty, Nov 2010 AAMC. Wilson BE, Morrison LA. Increasing Visibility for Faculty Achievement: The Promotion Poster Initiative at the University of New Mexico School of Medicine, AAMC Group on Faculty Affairs Aug 2011. Gonzales N, Gonzales J, Baca B, Morrison L. Finding the Founder of CCM1 in New Mexico. Angioma Alliance Pathobiology, presented Washington DC, October 2010. Khan YP, Kim H, Hart B, Morrison L. CCM in Hispanic Children in NM. Providence, RI, poster Child Neurology Society 2010 Morrison L. Clinical characteristics in CCM1. Presented Angioma Alliance Pathobiology, Washington DC, October 2010. Morrison, L, Scott, S. Tripling Women at UNM, AAMC Group on Faculty Affairs, Pittsburgh, PA, August 2008.

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Petersen TA, Hart BL, Morrison L. Familial Cerebral Cavernous Malformations and the Incidence of Concurrent Developmental Venous Anomalies in a Southwest Hispanic Population: A Retrospective Study. ASNR 46

th Annual

Meeting, New Orleans LA, June 2008.

Wenner D, Sanchez A, Gasparovic C, Buckholt J, Morrison L. Muscle Spectroscopy in Muscular Dystrophies. UNM Neurology Resident’s Day 2007 and Oculopharyngeal Muscular Dystrophy Family Meeting, National Hispanic Cultural Center November 17, 2007.

Armstrong T, Skipper B, Morrison L. The Trouble with Statins in OPMD. Medical Student Research symposium, Austin TX, May 2007.

Bale J, Anderson A, Bodensteiner J, Currey M, Dure L, Ferriero D, Firth S, Larson R, Koch T, Mack K, Ment L, Morrison LA, Percy A, Polsky D, Schor N, Tilton A. The Child Neurology Workforce Study I: Pediatrician Opinions Regarding the Supply of Child Neurologists in the United States (presented by James Bale, PAS, 2007). Bale J, Anderson A, Bodensteiner J, Currey M, Dure L, Ferriero D, Firth S, Larson R, Koch T, Mack K, Ment L, Morrison L, Percy A, Polsky D, Schor N, Tilton A. The Child Neurology Workforce Study II: Pediatrician Access to and Satisfaction with Child Neurology Consultation (presented by James Bale, PAS, 2007).

Devier D, Gasparovic C, Jung R, Campbell R, Tobon A, Morrison L. Temporal Lobe Biochemistry and Neurocognitive Function in Myotonic Dystrophy, ISMRN 2006.

Palmer P, Romero Clark C, Coe T, Morrison L, Garrison K, Wiest P, Spafford M. Swallow Deficits in a Northern New Mexico Cohort of Patients with OPMD. Dysphagia Research Society, 2005. Morrison L, Neel A, Palmer P, Romero-Clark C, Sprouls G. Voice, Speech and Swallowing Characteristics in Patients with OPMD. Poster, American Speech and Hearing Association annual meeting, 2005. Jaramillo J, Black R, Sandoval D, Chapin J, Morrison L, Allen RC. Ophthalmic and molecular characterization of Hispanic New Mexicans with OPMD. Presentation Association for Research in Visual and Ophthalmology May 2004. Morrison, LA. A Novel Approach to Development of a Research Database in OPMD. Journal of Child Neurology, March 2003;18(3):203 VI-3. Knupp-Peterson K, Morrison LA. X-linked spinal muscular atrophy in a neonate, Journal of Child Neurology March 1999;14 (3):185. Shih J, Lewine JD, Orrison WW, Wical B, Morrison L. Magnetic source imaging localization of epileptiform spikes in benign Rolandic epilepsy of childhood. AAN, 1996. Morrison LA. Congenital hypomyelination neuropathy. CKS, Journal of Child Neurology 1995;10:160-167. Morrison LA, Mandler R, Snyder R. Hereditary Madras syndrome, World Congress of Neurology, Can J of Neurol Sci 1993;20:S4:S81. Chapters: Dystrophinopathies. Handbook of Clinical Neurology. 2011; 101:11-39 (see also under peer-reviewed publications). Morrison, LA. Familial Cavernous Malformations: a historical survey. Cavernous Malformations of the Nervous System. ed. Daniele Rigamonti. Cambridge University Press 2011. Morrison, LA. Genetic Counseling. Cavernous Malformations of the Nervous System. Ed. Daniele Rigamonti. Cambridge University Press 2011.

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Morrison, LA. Guillain-Barré syndrome. Current Management of Child Neurology, 4th edition, Editor Bernard L. Maria, MD, ISBN 1550092928 BC Decker. Morrison, LA. Neuromuscular junction disorders. Current Management of Child Neurology, 3rd edition, Editor Bernard L. Maria, MD, ISBN 1550092928 BC Decker 2005 Morrison, LA. Guillain-Barré syndrome. Current Management of Child Neurology, 3rd edition, Editor Bernard L. Maria, MD, ISBN 1550092928 BC Decker 2005 Morrison, LA. Scoliosis. Treatment of Pediatric Neurologic Disorders, Harvey Singer, ISBN: 0824726936, Pub Date: Apr 1, 2005, Publisher: Taylor & Francis Snyder R, Morrison LA. Atypical infections of the CNS. Principles of Child Neurology, editor Bruce Berg, Mc-Graw-Hill 1996 Morrison LA, Green M. Development chapter, The Harriet Lane Handbook. Twelfth edition, Mosby Yearbook 1991 Book Review: Sturge-Weber Syndrome by Steve Roach and John Bodensteiner, Archives of Neurology 2000; 57(11). Non Peer-reviewed articles: Morrison LA, Treatment of Spasticity, Transverse Myelitis Association newsletter, 2003 Morrison LA, Tourette Syndrome, UNMH Health Smart newsletter, coordinated Child Neurology issue, Winter 2004 Morrison LA, A review of study results, Improving the Treatment of ADHD in Children and Adolescents: Nonstimulant Options, Education Editor Current Strategies for the Treatment of Attention-Deficit/Hyperactivity Disorder in Adults Education Editor Current Grant and Contract Funding: Research:

Biomarkers of Disease Severity in Hereditary Vascular Malformations PI: Morrison, Co0-PI Hart Univ of Utah PI: Kevin Whitehead

April 1 2013 to March 30 2014 Submitted 2-13

CTSC pilot award requested March 1, 2013

NIH FOR-DMD Site PI 2011-2016 Startup 3K, competitive enrollment

U54 NS065705-01 (Project 1: Principal Investigator) NIH / NINDS Brain Vascular Malformation Consortium: Predictors of clinical course, Project 1: Modifier genes in cerebral cavernous malformations PILOT project The Effect of Statins on Cavernous Malformation Permeability in Humans

6205 2009-2014

$50,000 in pilot award

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U54 NS065705-01 (Project 1: Principal Investigator) NIH / NINDS Brain Vascular Malformation Consortium: Predictors of clinical course, Project 1: Modifier genes in cerebral cavernous malformations

6201 2009-14 0.15 FTE effort

$273,583 direct/yr. 1 $1,480,836 total

UNM Myotonic Dystrophy Foundation. Studies of brain and muscle function in myotonic dystrophy.

Continuously since 2001.

Funding $30-40,000/year

Past Grant and Contract Funding: Medical safety monitor, Westat for NINDS, A Phase I/IIa Clinical Trial of Sodium Phenylbutyrate in Pediatric Subjects with Type II/III Spinal Muscular Atrophy, A multicenter trial of the NINDS pilot therapeutics network (NPTUNE), IND #75664 Follow-up Stansoporphin trial for neonatal hyperbilirubinemia, Invacare, 18 mo., 3 yr. cohorts, consultant Neurologist, amount approximately $15,000 each cohort study. Tierra Sagrada Foundation: Co-mentor, Establishing a Database of CCM1 Common Hispanic Mutation in NM, PI: Tina Peterson, MD, PGY1 Pediatrics (Co-mentor Blaine Hart, MD, Neuroradiology), Sept 1, 2007-August 31 2008 Amount: $18,000. Private donation for OPMD research $300 2004, purchased Progeny program with matched funds Neurology and Cell Biology Cody Unser First Step Foundation for the Study of Transverse Myelitis (awarded 10-3-01, unrestricted dates) $10,000 Research Allocation Committee grant (University of New Mexico), Molecular Basis of Oculopharyngeal Muscular Dystrophy in New Mexico, 7-1-99 through 6-30-00, $20,000 Gabapentin pediatric monotherapy trial: A multicenter, double-blind, placebo-controlled, parallel group study in pediatric patients with benign childhood epilepsy with centrotemporal spikes (BECTS), sponsored by Parke-Davis Pharmaceutical Company, 6-96. An extended open-label gabapentin pediatric monotherapy trial following a double-blind study in pediatric patients with benign childhood epilepsy with centrotemporal spikes (BECTS), sponsored by Parke-Davis Pharmaceutical Company, 6-96. Additional Research Grant Submissions: NCRR NM-INBRE subaward, Neuroimaging Markers in Cerebral Cavernous Malformations in New Mexico, PI Jeff Arterburn, PhD, NMSU, submitted 5/15/09, not funded Muscular Dystrophy Association Dynamic Structure of the Poly (A) Tail in mRNP Biology, PI David Bear, PhD submitted 07/08, not funded NIH, R21 conference grant, Genetic Diseases of the Hispanic Southwest, submitted 2005, PI L Morrison LA, Co-PI’s C Clericuzio, S Hordes, not resubmitted.

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NIH RO1, National Institute of Aging, OPMD in an Elderly Hispanic Cohort: Comorbidities, PI Morrison, LA, Co-I, K Tollestrup, D Bear, submitted 2004, not funded Muscular Dystrophy Association, A Natural History Study of OPMD in NM, submitted 2002, not funded NIH, KO1 mentored grant, Informed Consent in Genetic Research, PI Morrison, LA, Mentors Joan Gibson, Carol Clericuzio, and Susan Scott, submitted 1999, not funded Mentoring and Co-mentoring: Faculty Current: Sarah Youssof, MD, Assistant Professor of Neurology, 2009-, CTSC Certificate and Master’s program in Clinical Research 2011-2013, MDA Clinical Research Fellowship awarded 2013, 0.75 effort x 2 years. Sarah Pirio Richardon, MD, Assistant Professor of Neurology, 2008- , CTSC KL2 Scholar, Clinical Research Mentor 2011-2016, Career Development award granted Dystonia Coalition Tassy Parker, PhD, Assistant Professor of Family and Community Medicine, Director, Community Engaged Scholarship in Academic Affairs 2010-2011; Assistant Dean 2011- Bronwyn Wilson, MD, Professor of Internal Medicine, Assistant Dean Academic Affairs, 2009- ; Associate and Senior Associate Dean 2012- Glen Fenton, MD, Professor of Neurology 2010- Past: John Chapin, MD, Assistant Professor of Neurology, 2002-2008, mentoring in academic career path John Phillips, MD, Associate Professor of Neurology, 2000, facilitation of move from Pediatrics to Neurology department Nida Laurin, MD, Staff Physician, 2005, mentoring in research, career path Beth Goens, MD, Associate Professor of Pediatrics, since 2000, mentoring in negotiations, service provision Kathleen Ventre, MD, Assistant Professor of Pediatrics, 1999-2001, mentoring in academic career path, Pediatric ICU fellowship training Boston Children’s Hospital, 2001-2004, current faculty University of Utah Master’s and Ph.D. candidates: LaRee Gillaspie, Master Public Administration, Faculty Retention project and thesis 2010-2012 Gwen Sprouls, PhD, Speech and language pathology, OPMD project, 2008. Deidre Devier, MSW, psychology, mentor for clinical aspects of PhD dissertation “The temporal lobe in myotonic muscular dystrophy adults”, graduation May, 2006 Neurology Residents: Gowri Lakshimarayan, MD, Callosal lesion in pediatric epilepsy, poster Resident’s Day 2012, submission to AAN 2013 Antonio Vazquez, MD Seizures in CCM-pediatrics Resident’s Day 2010 Jorge Kawano, MD Seizures in CCM-Resident’s Day 2010 Amro El Feki, MD, Neurology resident’s day project, Evaluation and Treatment of Dysphagia in OPMD, submitted for publication 2009, presented June 2009 Stephen Gutu, MD and Amro El Feki, MD, The Consequences of Epilepsy in Cavernous Malformation patients, presented June 2010. Antonio Vazquez, MD and Vikas Gupta, MD. Death and Disability in Children with CCM1, presented June 2010. Vikas Gupta, MD, Endothelial Progenitor Cells in Cavernous Malformations, presented June 2009. Luzma Cardona, MD, Neuropathological Features of Pediatric Cavernous Malformations, presented June 2009 Alejandro Tobon, MD, Neurology resident’s day project, Correlations T2 Hyperintensities in DM1, June 2007, winner of award for best presentation, presented by David Holtzman, MD, Professor and Chair, Washington University, St Louis, MO Biljana Beretich, MD, Neurology resident’s day project, Neuromyelitis Optica, predictors of outcome, June 2007 (co-mentor)

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Juan Figueroa, MD, Neurology resident’s day project, Ultrasonographic Imaging of the Tongue in MG and OPMD, winner Best Research Project, awarded by visiting professor Lou Kaplan, June 2006, co-mentored by John Chapin, MD, winner of award for best presentation Alejandro Tobon, MD, Neurology resident’s day project, Volumetric Analysis of T2 Hyperintensities in DM1, June 2006 Nelson Hwynn, MD, Neurology resident’s day project, Parturition in CCM1, June 2006 Nida Laurin (aka Laurinaviciene), MD Neurology resident’s day project, Acute Transverse Myelitis in NM, presented Resident Research Day, June 2005 Nida Laurinaviciene, MD, Pediatric Guillain-Barre and variants, presented Neurology Resident Research Day, June 2004 Cameron Luo, MD, Cerebral Cavernous Malformations: outcomes, presented Neurology Resident Research Day, June 1999 Waseem Ahmed, MD, Cerebral Cavernous Malformations: comparison of pediatric and adult lesions by MRI) presented Neurology Resident Research Day, June 1998 Pediatric Residents: Tina Petersen, MD 2007-2009 Obstetrics and Gynecology Residents: Beatris Barrera, MD 2002- Faculty Advisor: Jenny Guerre, MD 2009-2010 Luzman Cardona, MD 2008-2009 Husseina Saria, MD 2007-2008 Biljana Beretich, MD 2005-2006 Nelson Hwynn, MD 2004-2005

Medical Students: Brandi Barringer, MS Urine Biomarkers of Cerebral Cavernous Malformations 2012- John Davis, MS Urine Biomarkers of Cerebral Cavernous Malformations 2012- Anastasios Manole, MS Dermatologic Aspects of CCM1-Common 2012- Hispanic Mutation Nina Gonzales, MD 2011, Finding the Founder: Genealogy in CCM1 2007-2011 Anesthesiology Intern, Psychiatry resident UNM Bea Villareal Barrera, MD 2010, Parturition in CCM1-CHM 2007-2010 Medical Student poster UNM April 2010 Obstetrics and Gynecology resident UNM 2010- Katrina Peariso, MD 2008, research project, the de Sanctis Cacchione Xeroderma Pigmentosum in Native American tribe Child Neurology fellow, Ohio 2008 Poster Child Neurology Society, Santa Clara, CA 2008 Tina Peterson, MD, HO1 Pediatrics, DVA and CM’s, La Tierra Sagrada grant 2007-2008 Practicing pediatrician (2010-) Jayme Heath, MD 2009, required research project mentor, 2009 A natural history of Niemann Pick type C in New Mexican patients Pediatric Residency Don Wenner, MD 2008, research project mentor 2005-2008 Phosphorus MRS in OPMD and DM1 Urology resident Adolfo Sanchez, MD 2008, research project mentor 2005-2008 Phosphorus MRS in OPMD and DM1 Family Practice Residency

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Practicing physician, Belen, NM (2012- ) Tara Armstrong Zamora, MD, Phase I, research project mentor 2004-2007 Hyperlipidemia in Oculopharyngeal Muscular Dystrophy Pediatric Residency U of Minnesota Emily Gilmore, MD, Phase II continuity clinic preceptor 2005 Neurology residency Yale and Columbia Neurocritical Care fellowship *Faculty Columbia-Presbyterian, NYC, NY Jamie Dubois Dermon, MD, MS II, Stanford School of Medicine 2005 CCM Research project Emergency Medicine resident

Faculty U of Arizona (2011- ) Jennifer Huffman, MD 2002 Pediatric and Neurology fellowship, Johns Hopkins Practicing Child Neurologist, Portland ORE Kelly Knupp, MD 1997 Pediatric, Neurology and Epilepsy Fellowship, Columbia, NY Faculty Columbia-Press (2008-2010), U of Colorado (2010- )

Undergraduate Students: Jessica Hall Weems, UNM graduate, engineer at Sandia National Laboratory clinical preceptorship 2004, medical school application 2005 Meghan Dougherty, UNM premedical curriculum 2003 Beatris Villareal Barrera (see OB residents) 2002 Aria Cook, Los Lunas High School, Honor Student, 2001 Adolfo Sanchez, UNM undergraduate students (OPMD project) 2001-2002 Emily Crump UNM undergraduate student, Regent’s Scholar 2004 Fauzia Malik, Albuquerque Academy, pharmacist 1998 Brenda Pacheco, University of New Mexico 1997

Graduate Physician Assistant program 2007 Practicing PA Taos, NM

Middle School: Jovahne, 8

th grade Gifted student, Truman MS 2012

Other Teaching: Didactic Resident presentations: 3-4 per year (Neurology and Pediatrics) 1992-2012 Journal club: 1-2 annually 1992-2012 CPC: semi-annual Oral exam: 1-2 pediatric neuromuscular patients (ongoing) Resident applicant interview committee, review of applications, interviews of approximately half of applicants, approximately 15 hours total per year 1992-2012 then pediatric neurology only. Medical School Classroom, laboratory teaching, and tutoring: Phase II 2000-2009 Neurology Tutorial, 5-8 students, 4 weekly sessions/year Didactic Sessions Pediatrics

2-18-05, 8 students, evaluations average 4.75 out of 5 (excellent) 6-8-05. 12 students, evaluation Clinical examination: Cranial Nerve exam: Small group sessions General Neurology exam: Small group sessions

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Continuing Medical Education Child Neurology Society, annual meetings 1999-2005 Others documented in teaching, and invited presentations

Clinical Resident Education (Neurology and Pediatric residents) Consultation service

Neurology resident 10-12 weeks per year, several hours per day, bedside teaching throughout rounds Pediatric or other rotating resident 4 weeks per year, several hours per day, bedside teaching throughout Case conference: presented weekly by on-service resident, mentored by attending physician, 12 weeks per year, and participation by all faculty (teaching), residents (supervised teaching), and students weekly

Interview committee: Review applications and interview approximately half of applicants, participate in selection committee meeting annually. Program review committee and interviews: RRC, fellowship program reviews, approximately one per year. Medical Student Education (Neurology and Pediatric students) Continuity clinic (2000-2005, weekly September through February) Agatha Norwood 2004-2005

Emily Gilmore 2003-2004 Christopher Adams 2002-2003

Susan Berendzen 2001-2002 Formal lectures in Phase I and II

Paroxysmal Events in Pediatric Neurology (2-3 per year, 75 minute lecture to phase II neurology students) Neurodevelopment (1-2 per year, one hour lecture to phase II pediatric students) Spinal Fluid Analysis (annual with tutorial group)

Phase I Neurology: Case development, Reviewer: Duchenne Muscular Dystrophy review, primary author David Bear, PhD Primary author: Tourette Syndrome, facilitator Mary Johnson, MD

Lab sessions Weekly Child Neurology case conference (see above under resident) one hour Other Teaching: Occupational Therapy, Myelomeningocele lecture 2006 Panel for Ethical Considerations in Gene Therapy 2002 Ethics Curriculum for Residents and Fellows 2001 Physical Therapy, Neurology course, Neuromuscular Disorders lecture 1992-1999 Service: Out-patient clinics Cerebral Cavernous Malformations 2005- Oculopharyngeal Muscular Dystrophy 2001-2010 Pediatric Muscular Dystrophy 1992-

Outreach clinics 1992-2009 Neurogenetic clinic 2004-2009

In-Patient Child Neurology consultation (10-24 weeks per year) 1992-2012 Administration: University Committees: Presidential Inauguration HSC presentation task force 2012 UNM President David Schmidley’s task force on Parental Leave policy 2007 Department: Retreat organizing committee, Chair searches, Pediatrics, Pathology

Nominating Committee, Medical Executive Council New Mexico VA coordinating committee 2009-

High Level Searches for UNM HSC, Chair

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History of Medicine 2012 Assistant Dean for Academic Affairs SOM 2012 Psychiatry Chair 2011

Associate Chief Diversity Officer 2011 Chief Office of the Medical Investigator 2011 Director, Interprofessional Education 2012 Search Committees: Pediatric epileptologist 2008-2009 Neuromuscular specialist 2008-2009

Assistant Dean, Academic Affairs 2008, 2012 Pediatric Neurosurgeon 2005 Pediatric Physiatry 2004-2005 Division Chief Neonatology 2001-2002 Child Neurology 1999-2000 Neuromuscular specialist 2001 Epileptologist 2004-2007

UNM HSC Strategic Planning Core 2012 UNM HSC Clinical Enterprise Strategic Plan, Organizational Culture 2004 UNM HSC Ethics Institute advisory board 2002 Medical Executive Council, November 2001-2003 Biomedical Ethics Committee 1994-2000 Medical Records Committee 1994-2000 Departmental Committees: Chairman’s Advisory Committee 1998- Residency Concerns Committee (former chairperson) 1994-2005 Faculty Retreat Chair 1999-2005 Staff Interview committees: Unit Director search for Clinical Neurosciences Center Neurology Nurse-Practioner search, Department accountant Research Nurse Myotonic dystrophy Research Coordinator, managers, data entry International Committees and Related Work: Congenital Myopathy Standard of Care Congenital Muscular Dystrophy AAN practice guideline, facilitator, funded by CDC Spinal Muscular Atrophy Standard of Care (collaborative support NIH, MDA, SMA organizations) Duchenne Muscular Dystrophy (funded by CDC) Angioma Alliance Invited Lectures and Other Teaching: 2012 Angioma Alliance session moderator, panelist, speaker University of California San Francisco “CCM in New Mexican Families” AAMC Equity symposium speaker AAMC GFA Faculty Forward introduction Angioma Alliance national family meeting “UNM Research Update” 2011 AAMC C-change presentation, Faculty Forward presentation Angioma Alliance, Chantilly, France

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Update Neurogenetic Disorders, Albuquerque, NM 2010 New Mexico Medical Society History of Medicine, Taos NM 6 Cavernous Angioma family meetings (Baca La Tierra Sagrada grant) Taos (2), Santa Fe, Las Vegas, Las Cruces, Albuquerque 2009 AAMC national meeting: C-changes in New Mexico C-change LAN 6, Wye River, MD, Easy Wins AAMC Mid-Career Career Mapping leader, Negotiation in a Multicultural World, Scottsdale, AZ Adrenoleukodystrophy, Pediatric Case Conference, UNM CCM in New Mexico, Angioma Alliance Pathobiology conference, Santa Fe, NM Advances in Muscular Dystrophy Treatment, OPMD family conference, Albuquerque, NM Spinal Muscular Atrophy Standards of Care, Atlanta, GA 2008 The Role of Neuroimaging in Management of Cavernous Malformations, UNM Neuro Update, Albuquerque, NM Cavernous Malformations: A public health issue in New Mexico, New Mexico Medical Society, Albuquerque, NM Schwartz-Jampel in Hispanic New Mexicans, Congenital Muscular Dystrophies workshop participant, Iowa City, IA OPMD in Hispanic New Mexicans, Taos, NM 2007 OPMD in Hispanic New Mexican families, Farmington, NM Correlation between cavernomas and developmental venous anomalies in CCM1 Common Hispanic Mutation, Angioma Alliance, Pathobiology meeting, Washington, DC Cerebral cavernous malformations and the Common Hispanic Mutation, Faculty and Resident lecture, Quebec, CAN Cerebral Cavernous Malformations in New Mexico, Grand Rounds, Santa Fe, NM Pediatric Transverse Myelitis and ADEM, Southwest Neuroimmunology conference, Albuquerque (Chair) 2006 Clinical Features of The Common Hispanic Mutation, Pathobiology meeting, Angioma Alliance, Washington, DC Pediatric Angiomas, Angioma Alliance National Family Meeting, Santa Fe, NM 2005 Oculopharyngeal Muscular Dystrophy, National MDA Directors Meeting, Tucson, AZ Imaging in Children with Cerebral Cavernous Malformations, Angioma Alliance. Baltimore, MD International Workshop on Paroxysmal Disorders in Infancy, Malignant Epilepsy in a Native American cohort, Islay, Scotland Grand Rounds, University of Texas, El Paso, Genetic Epilepsies Oculopharyngeal muscular dystrophy in Hispanic New Mexicans, Hispanic Genealogical Research Consortium, Albuquerque, NM Schwartz-Jampel syndrome in Hispanic New Mexicans, Carrell-Krusen, Dallas, TX Cerebral cavernous malformations in Hispanic New Mexicans, Hispanic Genealogical Research Consortium, Albuquerque, NM 2004 Epilepsy Runs in My Family, LAB Epilepsy Research Group, Inc., Long-Term Management of Pharmaco-resistant Epilepsy, Albuquerque, NM 2003 Santa Fe Pediatric Update, What’s New in Neuro?, Santa Fe, NM

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Overview of Oculopharyngeal muscular dystrophy in New Mexico, OPMD family conference Medications old and new, Pediatric Epilepsy for Primary Care New Mexico Pediatric Society, Wylder lecture series, Pediatric Spells workshop, Albuquerque, NM Life Expectancy in Cerebral Palsy, Office of Legal Education of the US Department of Justice, Advanced Medical Malpractice Seminar, Columbia, SC OPMD in New Mexico, Carrell-Krusen, Dallas, TX Pediatric Epilepsy symposium, Sedona, AZ 2002 Headaches in Children, Zuni Medical Center, CME, Zuni, NM Management of Spasticity in Children with Transverse Myelitis, Vaccination Panel, and Use of Electrical Muscle Stimulation: TES (Threshold Electrical Stimulation) and NMES (Neuromuscular Electrical Stimulation), Transverse Myelitis Association Children’s and Family Workshop, Columbus, OH Treatment of Duchenne Muscular Dystrophy: Overview, Parent Project Muscular Dystrophy annual conference, Bridging the Gap, Pittsburgh, PA Pediatric Transverse Myelitis, and Management of Spasticity in Transverse Myelitis, California Transverse Myelitis Conference, hosted by Cody Unser First Step Foundation and the Reeve-Irvine Research Center, CA Phenotypes and Genotypes in Partial Epilepsies of Childhood, Novartis, Sedona, AZ Common Problems in Child Neurology, Advances in Neurology, Santa Fe, NM Neurological Complications of Achondroplasia, Carrie Tingley Winter Seminar The Brain in Children with Myotonic Dystrophy, SCN, Sea Island, GA Pediatric Stroke, UNM Neurology Update, Santa Fe, NM 2001 Research Ethics in Neurogenetic Disorders in New Mexico, Ethics Resident Seminar series, UNM Pediatric Epilepsy, Indian Health Service Grand Rounds, Albuquerque, NM Matrix Metalloproteinases, Johns Hopkins 2

nd International Transverse Myelitis Symposium, Baltimore, MD

Management of Spina Bifida, National Indian Health Service National Pediatric meeting, Phoenix, AZ Pediatric Epilepsy Mimics, National Indian Health Service National Pediatric meeting, Phoenix, AZ Movers and Shakers, Presbyterian pediatric grand rounds, Albuquerque, NM Ethics of Genetic Research in Native Americans, Pros and Cons: Ethical, Legal and Social Implications of Human Genome Project, and University of Colorado, Aspen, CO Ethics of Neurogenetic Informed Consent in Hispanic Populations, Ethics Curriculum for Faculty Scoliosis in Duchenne Muscular Dystrophy, Carrie Tingley Winter Seminar, Albuquerque, NM Post-infectious Neurological Disorders in Children, UNM Pediatric Resident lecture 2000 Conditions that Mimic Seizures, Presbyterian, Albuquerque, NM Genetic Disorders of New Mexico, Clinical Neuroscience Albuquerque Hilton Hotel Oculopharyngeal Muscular Dystrophy in New Mexico, SCN Newfoundland, CAN Neurogenetic Disorders of the Southwest, Neuroscience Update, Albuquerque, NM Grand Rounds, University of New Mexico: Can you prevent hemorrhage in Cerebral Cavernous Malformations 2011 Cerebral Cavernous Malformations in New Mexican Children 2010 Congenital Muscular Dystrophies, Neurology 2008 Where in the World is De Sanctis Caccione? Pediatrics 2007 Emerging Treatments in Genetic Neuromuscular Disorders, Neurology 2005 Genetic Disorders of New Mexico, Pediatrics 2005 Oculopharyngeal Muscular Dystrophy in New Mexico: an Update 2004 Juvenile Huntington Disease 2004 Pediatric Cerebral Cavernous Malformations in New Mexico 2003 Pediatric Myotonic Dystrophy, Pediatrics 2003

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Schwartz-Jampel Syndrome in New Mexico 2003 The Genetics of Partial Epilepsies 2002 Oculopharyngeal Muscular Dystrophy in New Mexico 2001 Spina Bifida: Causes and Cures 2001 Movers and Shakers: Epilepsy Mimics 2000 The Brain in Children with Myotonic Dystrophy 1999 Conference Organization: Chairperson, OPMD in New Mexico, National Hispanic Cultural Center 2007, 2009 Chair/Director, Neuroimmunology Seminar 2007 Chairperson, OPMD MDA Family Conference II, 2005 Muscular Dystrophy Research dinner host 2000 Carrie Tingley Hospital Selected Topics in the Management Spinal Cord Injury/Dysfunction in Children, Moderator 2005 Chairperson, Duchenne and Becker Muscular Dystrophies for Families 2004 Chairperson, Pediatric Epilepsy for Primary Care 2003 Chairperson, OPMD in New Mexico, National Hispanic Cultural Center 2003 Co-chair, Neurology Update 1994 Community Service: MDA NM executive board member 2004- Press conference, Governor Bill Richardson for Stem Cell research NM 2008 External Review Panel: New Mexico Public Regulation Commission 2003 Presentation to PEO, Myotonic Muscular Dystrophy 2005 Spinal Muscular Atrophy, Benefit for Fight SMA, Sandoval County 2005 Cody Unser First Step Foundation 2005 PEO meeting, Myotonic muscular dystrophy 2005 Fight Spinal Muscular Atrophy Benefit 2004 Children’s Miracle Network Telethon, television interview 2004 Volunteer Children’s Hospital Soccer Charity 2001 Cody Unser, Transverse Myelitis Golf Tournament 2001 Volunteer UNM Children’s Hospital Soccer Charity 2001 The Brain and Nutrition, Alvarado Elementary School 2000 Special Contributions: Sun-Kissed, a film by Adi Levy, PBS October 2012 release (Xeroderma Pigmentosum, Navajo) Interview 2012 MDA fundraisers, OPMD support group 2009 “Cody” film released for Public Television 2009 Piano performance, 88 Keys for Kids benefit UNM Children’s 2005 Genetic Research in Native Americans: Ethics, film for UNM 2003 Revised: November 6, 2012