Lecture 6 Periapical Periodontitis (Slide)

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    Periapical PeriodontitisPeriapical Periodontitis

    Dr. Rima SafadiDr. Rima Safadi

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    Periapical PeriodontitisPeriapical Periodontitis

    Acute and chronic periapical periododntitisAcute and chronic periapical periododntitis

    Dynamic processDynamic process

    Rich periapical collateral circulationRich periapical collateral circulation Enhances ability of tissue to healEnhances ability of tissue to heal

    Often accompanied by resorption of boneOften accompanied by resorption of bone

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    Etiology/ Periapical PeriodontitisEtiology/ Periapical Periodontitis

    Pulpitis and pulpPulpitis and pulp

    necrosisnecrosis

    Bacterial toxinsBacterial toxins

    Products ofProducts ofinflammationinflammation

    TraumaTrauma

    Occlusal traumaOcclusal trauma

    Orthodontic treatmentOrthodontic treatment

    Biting on a hard bodyBiting on a hard body

    Often acute, transientOften acute, transient

    Endodontic treatmentEndodontic treatment::

    MechanicalMechanical

    ChemicalChemical

    BacterialBacterial

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    Acute Periapical PeriodontitisAcute Periapical Periodontitis

    Acute exudateAcute exudate

    Confined spaceConfined space

    Thermal stimuli and painThermal stimuli and painLocalized painLocalized pain

    Proprioceptive nerve endings in PDLProprioceptive nerve endings in PDL

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    Acute Periapical PeriodontitisAcute Periapical Periodontitis

    Radiographically:Radiographically:

    normalnormal

    Or slight widening ofOr slight widening of

    PDLPDL Less well definedLess well defined

    lamina duralamina dura

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    Acute Periapical PeriodontitisAcute Periapical Periodontitis

    Out comes:Out comes:

    Resolve if trauma is transientResolve if trauma is transient

    Chronic periapical periodontitis: if irritationChronic periapical periodontitis: if irritation

    persistspersists

    Acute periapical abscess (massive exudate)Acute periapical abscess (massive exudate)

    If severe irritation persists like tissue necrosisIf severe irritation persists like tissue necrosis

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    Chronic periapical periodontitisChronic periapical periodontitis

    Persistent irritationPersistent irritation

    Resorption of periapicalResorption of periapical

    alveolar bonealveolar bone

    Replaced by inflamedReplaced by inflamed

    granulation tissuegranulation tissue

    Dense bundles of collagenDense bundles of collagen

    fibers at peripheryfibers at periphery

    Capsule likeCapsule like

    Attached to root apeAttached to root apexx

    Asymptomatic or mildAsymptomatic or mild

    tenderness to percussiontenderness to percussion

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    Chronic periapical periodontitisChronic periapical periodontitis

    Radiographically:Radiographically:

    Widening of PDLWidening of PDL

    Well circumscribed RLWell circumscribed RL

    with or withoutwith or withoutcorticationcortication

    Based on cellularBased on cellular

    activity of marginactivity of margin

    Resorption ofResorption of

    cementum or dentinecementum or dentine

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    Periapical GranulomaPeriapical Granuloma

    A localized mass of chronically inflamedA localized mass of chronically inflamed

    granulation tissue that forms at the apex of agranulation tissue that forms at the apex of a

    non-vital tooth root.non-vital tooth root.

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    Periapical granulomaPeriapical granuloma

    HistologicallyHistologicallyGranulation tissue: infiltratedGranulation tissue: infiltratedmainly by lymphocytes,mainly by lymphocytes,macrophages and plasmamacrophages and plasmacellscells

    Antigenic stimulation from theAntigenic stimulation from thepulppulp

    Cholesterol clefts formationCholesterol clefts formation

    Haemosidren depositsHaemosidren deposits

    Multinucleated giant cellsMultinucleated giant cells

    Foam cells-lipid ladenFoam cells-lipid ladenmacrophagesmacrophages

    Proliferation of epithelial restsProliferation of epithelial restsof Malassezof Malassez

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    Proliferation of epithelial cell rest ofProliferation of epithelial cell rest of

    MalassezMalassez

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    Sequelae of Periapical GranulomaSequelae of Periapical Granuloma

    1. Equilibrium with host immunlogic response:1. Equilibrium with host immunlogic response:static for yearsstatic for years

    2. Acute exacerbation2. Acute exacerbation

    Patient with acute symptomsPatient with acute symptoms3. Suppuration:3. Suppuration:

    AcuteAcute periapical abscessperiapical abscessRapid onset of pain and swelling, tenderness to percussionRapid onset of pain and swelling, tenderness to percussion

    ChronicChronic Abscess: little tendency to enlalrge or spreadAbscess: little tendency to enlalrge or spread4. Proliferation of epithelial cell rests of Malassez4. Proliferation of epithelial cell rests of Malassez

    Radicular cystRadicular cyst

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    Sequelae of Periapical GranulomaSequelae of Periapical Granuloma

    5. Osteosclerosis: low5. Osteosclerosis: low

    grade irritationgrade irritation

    6. Hypercementosis6. Hypercementosis

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    Periapical AbscessPeriapical AbscessRadiographic FeaturesRadiographic Features

    If abscess develops directlyIf abscess develops directlyfrom pulp inflammation andfrom pulp inflammation andnecrosis, there may be nonecrosis, there may be noradiographic changes initially,radiographic changes initially,

    except forexcept forslight widening ofslight widening ofthe PDL space.the PDL space.

    If the abscess developsIf the abscess develops

    through acute exacerbation inthrough acute exacerbation inan area of previously existingan area of previously existingchronic inflammation, achronic inflammation, a distinctdistinctradiolucent area is seen at theradiolucent area is seen at theapex.apex.

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

    From acute PAFrom acute PA

    periodontitisperiodontitis

    Or chronic PAOr chronic PA

    granulomagranulomaBacteriology: mixedBacteriology: mixed

    infection mainlyinfection mainly

    anaerobesanaerobes

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

    Routes of Spread:Routes of Spread:

    Through root canalThrough root canal

    PDL into gingival sulcusPDL into gingival sulcusThrough Cancellous bone and perforatesThrough Cancellous bone and perforates

    cortexcortex

    Lingual plates are denser than buccalLingual plates are denser than buccal Origin of muscles guides spread of pusOrigin of muscles guides spread of pus

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

    Drain into oral cavity via a sinusDrain into oral cavity via a sinus

    Small swelling may develop before openingSmall swelling may develop before opening

    A nodule of granulation tissue marks theA nodule of granulation tissue marks the

    opening of sinusopening of sinus

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

    Palatal abscessPalatal abscess

    Molar regions of bothMolar regions of both

    jaws:jaws:

    Penetrate above orPenetrate above orbelow buccinatorbelow buccinator

    muscle attachments:muscle attachments:

    CellulitisCellulitis

    Localized soft tissueLocalized soft tissueabscessabscess

    Drain on skinDrain on skin

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

    Anterior maxillary teeth:Anterior maxillary teeth:

    Upper lipUpper lip

    Perforate abovePerforate above

    attachment of lip muscles:attachment of lip muscles:

    infection passes to innerinfection passes to innereye canthus, nasolabialeye canthus, nasolabial

    fold, lower eyelidfold, lower eyelid

    Maxillary molars:Maxillary molars:

    discharge into thedischarge into the

    maxillary sinusmaxillary sinus

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    Acute periapical abscess andAcute periapical abscess and

    spread of inflammationspread of inflammation

    Mandibular premolarMandibular premolaror molar: belowor molar: belowattachment of MHattachment of MHmusclemuscle Submandibular space,Submandibular space,

    communicates withcommunicates withlateral pharyngeallateral pharyngealspacesspaces

    Mandibular incisor:Mandibular incisor:subcutaneoussubcutaneousabscessabscess

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    CellulitisCellulitis

    Rapid spread of inflammationRapid spread of inflammationof the soft tissues associatedof the soft tissues associatedwith streptococcal infectionwith streptococcal infection

    Large amounts ofLarge amounts ofstreptokinase andstreptokinase and

    hyaluronidasehyaluronidase Mainly: InflammatoryMainly: Inflammatory

    edemaedema

    ClinicallyClinically

    Poorly localizedPoorly localized PainfulPainful

    MalaiseMalaise

    Elevated temperatureElevated temperature

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    Complications: Cavernous sinusComplications: Cavernous sinus

    thrombosis due to involvement of veins atthrombosis due to involvement of veins at

    inner canthus of the eyeinner canthus of the eye

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    Ludwig`s anginaLudwig`s angina

    Severe cellulitis initially involvingSevere cellulitis initially involving

    submandibular spacesubmandibular space

    SwellingSwelling inin floor of the mouth, elevatedfloor of the mouth, elevated

    tonguetongue

    edema of glottis may occuredema of glottis may occur