Lecture 2 – Introduction to autism research Ilan Dinstein.
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Lecture 2 – Introduction to autism research Ilan Dinstein
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Transcript of Lecture 2 – Introduction to autism research Ilan Dinstein.
Determine the function of the gene
What is the function of the protein that the gene encodes?
Is it involved in neural transmission?
Neural development?
Synaptic development?
Bourgeron 2009
Create a genetically modified animal model
Control > ASD
Compare animals with extremely similar genetics except for a specific modification.
What about humans?
Human genetics – SFARI, Autism Speaks
Neuroimaging – MRI, fMRI, DTI
Electrophysiology – EEG
Post mortem