lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty...

37
Molecular Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and J. Fraser Stoddart, in nanostructured Materials and Nanotechnology, Hari Sigh Nalwa (Ed). Academic Press, New York, 2002.

Transcript of lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty...

Page 1: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Molecular Nanomachines

Feynman – “There is plenty of room in the bottom”

Bottom-Up approach

Lecture 17

Ref: M. Gomez-Lopez and J. Fraser Stoddart, in nanostructuredMaterials and Nanotechnology, Hari Sigh Nalwa (Ed). Academic Press, New York, 2002.

Page 2: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Gordon E. Moore observed that at our rate of technological development and advances in the semiconductor industry, the number of transistors on integrated circuits (a rough measure of computer processing power) doubles every 18 months. We should expect thatin 10 years computers will be about 100 times more powerful than they are today.

Page 3: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Writing

Erase

Reading

Switch

Page 4: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Molecular brake

Conformational changes

Page 5: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Configurational change

Page 6: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Problem of side reactions

Page 7: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Problem: Thermal re-isomerisation

Page 8: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 9: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Chiroptical switches

Page 10: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Colourless Coloured

Photochemical changes

Page 11: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 12: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Written state

Permanent storage

Page 13: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Colourless Coloured

Page 14: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Combining photo/electro/biochemistry

Page 15: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Use of metal complexes

Page 16: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Photochemically induced isomerisation

Page 17: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 18: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

On-Off fluorescence

Page 19: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Fluor-spacer-receptor methods

Page 20: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Complexationswitching

Bipyridyl – FeIIHydroxamate - FeIII

Page 21: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Translocation of cations

Page 22: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Photoswitchable complexation

Page 23: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Dendritic boxes : host – guest chemistry

Page 24: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Supramolecular motion

Page 25: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Electrochemically controlled machine

Page 26: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Logic gates

AND function

Page 27: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Molecular shuttles

Page 28: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Light driven shuttle

Page 29: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 30: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 31: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 32: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Applications

Sensors

Page 33: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and
Page 34: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

10 - 100 nm

y [ M n + + n e ] X - R - Y M X R Y

X R Y

1 - 1 0 n m M e t a l o x i d e p r e c u r s or

X R Y

X R Y O x i d e

M e t a l c o r e

20-50 nm

Clusters with Oxide Cover

New composite materials

Page 35: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Ru||

OOP

ON

N

NN N

N

O PO

O

N+

N+

PO(OH)2

PO(OH)2

Conducting Glass

Nanostructured TiO2 Film

TiO2

TiO2-RV

Page 36: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Modified electrodes

Page 37: lecture 17, 2004 - Indian Institute of Technology Madras Nanomachines Feynman – “There is plenty of room in the bottom” Bottom-Up approach Lecture 17 Ref: M. Gomez-Lopez and

Endless possibilities…!


Visualization for Active learning: Understanding Nanomachines

Visualization for Active learning: Understanding Nanomachines

G52CMP: Lecture 7 - cs.nott.ac.ukpsznhn/G52CMP-Obsolete/Lecture... · G52CMP: Lecture 7 Syntactic Analysis: Bottom-Up Parsing Henrik Nilsson University of Nottingham, UK G52CMP: Lecture

G52CMP: Lecture 7 - cs.nott.ac.ukpsznhn/G52CMP-Obsolete/Lecture... · G52CMP: Lecture 7 Syntactic Analysis: Bottom-Up Parsing Henrik Nilsson University of Nottingham, UK G52CMP: Lecture

Functional nanomachines: Recent advances in synthetic ...szolcsanyi/education/files/The... · Functional nanomachines: Recent advances in synthetic molecular machinery James A. Findlay,

Functional nanomachines: Recent advances in synthetic ...szolcsanyi/education/files/The... · Functional nanomachines: Recent advances in synthetic molecular machinery James A. Findlay,

Nanobiology Enzymes as nanomachines Molecular motors Fluctuations in gene expression Fluctuations in gene splicing Copyright Stuart Lindsay 2009.

Nanobiology Enzymes as nanomachines Molecular motors Fluctuations in gene expression Fluctuations in gene splicing Copyright Stuart Lindsay 2009.

RICE UNIVERSITY Design, Synthesis, and Monitoring of Light-Activated Motorized Nanomachines

RICE UNIVERSITY Design, Synthesis, and Monitoring of Light-Activated Motorized Nanomachines

Lecture 6: Bridging the Gap between Bottom-up & Top-down … · Bridging the Gap between Bottom-up & Top-down Modeling Approaches Justin M. Calabrese ... Strengths of bottom-up approach

Lecture 6: Bridging the Gap between Bottom-up & Top-down … · Bridging the Gap between Bottom-up & Top-down Modeling Approaches Justin M. Calabrese ... Strengths of bottom-up approach

6.006 Lecture 19 Original: Memoization, subproblems ... · Title: 6.006 Lecture 19 Original: Memoization, subproblems, guessing, bottom-up; Fibonacci, shortest paths Author: Demaine,

6.006 Lecture 19 Original: Memoization, subproblems ... · Title: 6.006 Lecture 19 Original: Memoization, subproblems, guessing, bottom-up; Fibonacci, shortest paths Author: Demaine,

Syntax Analysis – Bottom Up Parsing 1 Analysis...Syntax Analysis – Bottom Up Parsing 1 . CMPSC 470 Lecture 07 . Topics: • A. Bottom-up parsing concept A bottom-up parser constructs

Syntax Analysis – Bottom Up Parsing 1 Analysis...Syntax Analysis – Bottom Up Parsing 1 . CMPSC 470 Lecture 07 . Topics: • A. Bottom-up parsing concept A bottom-up parser constructs

Compilation 0368-3133 Lecture 4: Syntax Analysis Bottom Up parsing Noam Rinetzky 1.

Compilation 0368-3133 Lecture 4: Syntax Analysis Bottom Up parsing Noam Rinetzky 1.

CSC384: Lecture 3CSC384: Lecture 3 Last time • DCL: syntax, semantics, proofs • bottom-up proof procedure Today • top-down proof procedure (SLD-resolution) • perhaps start

CSC384: Lecture 3CSC384: Lecture 3 Last time • DCL: syntax, semantics, proofs • bottom-up proof procedure Today • top-down proof procedure (SLD-resolution) • perhaps start

CLT Exemplars Visualization for Active learning: Understanding Nanomachines By Adham Ramadan Department of Chemistry Flash animations by Reham Tallawi.

CLT Exemplars Visualization for Active learning: Understanding Nanomachines By Adham Ramadan Department of Chemistry Flash animations by Reham Tallawi.

Text Categorization Moshe Koppel Lecture 8: Bottom-Up Sentiment Analysis

Text Categorization Moshe Koppel Lecture 8: Bottom-Up Sentiment Analysis

CS 536 Spring 20011 Introduction to Bottom-Up Parsing Lecture 11.

CS 536 Spring 20011 Introduction to Bottom-Up Parsing Lecture 11.

Molecular chaperones are nanomachines that catalytically ...

Molecular chaperones are nanomachines that catalytically ...

Three routes to the manufacture of nanomachines: 1. Build proteins 2. Use the STM 3. Use chemistry.

Three routes to the manufacture of nanomachines: 1. Build proteins 2. Use the STM 3. Use chemistry.

Lecture 9 Bottom-up parsers Datalog , CYK parser, Earley parser

Lecture 9 Bottom-up parsers Datalog , CYK parser, Earley parser

Synopsis Nanomachines Nanoparticles Nanoelectronics Nanobiometrics Nanomanipulator Nanorobots Nanoelasticity Carbon Nanotubes.

Synopsis Nanomachines Nanoparticles Nanoelectronics Nanobiometrics Nanomanipulator Nanorobots Nanoelasticity Carbon Nanotubes.

Antimicrobial resistance (AMR) nanomachines—mechanisms for ... · generation of a number of mechanisms by which resistance canbemounted.Kaatzetal.(1991,1993)firstdescribedthree

Antimicrobial resistance (AMR) nanomachines—mechanisms for ... · generation of a number of mechanisms by which resistance canbemounted.Kaatzetal.(1991,1993)firstdescribedthree

CS 421 Lecture 9: Bottom-up Parsing

CS 421 Lecture 9: Bottom-up Parsing

ECE 410 Top Down Design Lecture - Michigan State …Top-down and bottom-up design • Bottom-up design creates abstractions from high detailed low-level designs • Top-down design

ECE 410 Top Down Design Lecture - Michigan State …Top-down and bottom-up design • Bottom-up design creates abstractions from high detailed low-level designs • Top-down design