Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal...
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Transcript of Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal...
![Page 1: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/1.jpg)
Lecture 12 – Second Messengers VI – Others
BIOL 5190/6190 Cellular & Molecular Singal TransductionPrepared by Bob Locy
Last modified -13F
![Page 2: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/2.jpg)
CSB Fig 02:01 Cell signalling pathways
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
![Page 3: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/3.jpg)
Transducers Second Messengers II
1. JAK/STAT signaling
2. Smad signaling3. Hedgehog signaling4. Wnt signaling5. Hippo signaling6. Notch signaling7. ER Stress signaling8. AMP signaling
![Page 4: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/4.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:72 JAK and STAT structure
![Page 5: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/5.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:73 STAT1/DNA complex
![Page 6: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/6.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:74 JAK/STAT heterogeneity
![Page 7: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/7.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:75 JAK/STAT function
![Page 8: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/8.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:76 Smad domain structure
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:77 TGF-βR activation
![Page 10: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/10.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:78 Smad signalling
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:79 Wnt signalling pathways
![Page 12: Lecture 12 – Second Messengers VI – Others BIOL 5190/6190 Cellular & Molecular Singal Transduction Prepared by Bob Locy Last modified -13F.](https://reader035.fdocuments.us/reader035/viewer/2022062217/56649cc25503460f9498b014/html5/thumbnails/12.jpg)
Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:80 Wnt canonical pathway
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:81 Hedgehog signalling pathway
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:82 Hippo signalling pathway
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:83 Notch signalling
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:84 Notch modulation
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:85 ER stress signalling
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:86 Metabolic messengers
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:87 Metabolic signalling
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:88 Pyruvate and Ca2+ signalling
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:89 AMPK structure
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CSB Fig 2:90 AMPK control of metabolism
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Cell Signalling Biology - Michael J. Berridge - www.cellsignallingbiology.org - 2012
CBS Fig 2:91 Omega-3 fatty acids