Lecture 1 - Intro to CPD

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  • Lecture 1 Introduction to

    Chemical Product Design

  • H83CPD - Chemical Product Design Lecture 1 - 2

    About the course Objective:

    In response to the need for curriculum changes in the subject area of chemical engineering, which have arisen as a result of profound changes in the chemical and process industries .

    To provide knowledge and understanding of the common approach used in designing chemical products.

    Meeting time & venue: Wednesday : EA29 (9.00 11.00)

    Thursday : F1A03 (01.00 02.00)

    Evaluation method and grading One 2-hour OPEN BOOK examination (75%).

    Course Work (20% on a product design project, with presentation and report)- both report and presentation slides due on April 27.

    In-class group activities (5%)- On Thursdays from week 2-week11

  • H83CPD - Chemical Product Design Lecture 1 - 3

    Performance in the last Year

    Average 52.6%

    Number of

    Students Percentage

    FL (0%-39%) 7 13.2%

    3rd (40%-49%) 15 28.3%

    2.2 (50%-59%) 16 30.2%

    2.1 (60%-69%) 10 18.9%

    1st (>70%) 5 9.4%

    Total 53 100%

    Overall Mark

    100%

    Average 52.6

    Maximum 80.0

    Minimum 26.0

  • H83CPD - Chemical Product Design Lecture 1 - 4

    Textbook & course material Cussler E. L. and

    Moggridge, G. D. Chemical Product Design, Cambridge University Press, 2001.

    The course material will be available on hand-outs.

    Lecture presentation (PDF files) & additional course material will be available in

    moodle.

  • H83CPD - Chemical Product Design Lecture 1 - 5

    Textbook & course material Chemical Product Design: Towards a

    Perspective through Case Studies edited by Ka M. Ng, Rafiqul Gani, Kim

    Dam-Johansen, 2007, 115.

    Product Design and Engineering: Best Practices

    edited by Ulrich Brckel, Willi Meier, Gerhard Wagner, 2007, 180.

    Product Engineering Molecular Structure and Properties

    by James Wei, 2007, 60.

    Design and Development of Biological, Chemical, Food and Pharmaceutical Products by Johannes A. Wesselingh, Sren Kiil, Martin E. Vigild, 2007, 29.95.

  • H83CPD - Chemical Product Design Lecture 1 - 6

    Lecture outline What is Chemical Product Design

    (CPD)?

    Why CPD is important? Changes in the chemical industry

    Changes in employment

    Trends in chemical engineering

    Changes in corporate culture Corporate organisation

    Corporate strategy

    The CPD procedure a glimpse & its controversy

    Concluding remarks

  • H83CPD - Chemical Product Design Lecture 1 - 7

    Chemical Engineering What is Chemical Engineering?

    One of the broadest fields of

    engineering

    Discipline is founded on

    Mathematics and on all the basic

    sciences namely, Physics, Chemistry

    and Biology

    A truly interdisciplinary field

    Other Engg mainly on Maths and

    Physics

    Multiscales of the Chemical Supply Chain

  • H83CPD - Chemical Product Design Lecture 1 - 8

    Chemical Engineering Paradigms

    0. Pre-paradigm - engineers with no formal education Descriptive treatment of specific processes (potash, sulfuric acid, soap)

    1. The first paradigm - Unit Operations, 1923 Processes broken into common, standard units such as heat exchange,

    distillation, crystallization, etc.

    2. The second paradigm - Transport Phenomena, 1960 Unified mathematical treatment of momentum, heat and mass transfer

    3. The third paradigm - Product Design? (Wei, Cussler) Product design requires consideration of specific materials properties

  • H83CPD - Chemical Product Design Lecture 1 - 9

    Chemical Engineering Paradigms

  • H83CPD - Chemical Product Design Lecture 1 - 10

    Chemical products We use many complex chemical products:

    Ice cream

    Paint

    Detergents

    Crisps

    Medicines

    Creams

    Print toner

    What are the similarities & differences among these products?

  • H83CPD - Chemical Product Design Lecture 1 - 11

    Granules Transdermal

    patches

    Creams LCD Display

    UV Sensor

    11

    Powder/

    Composite

    solids

    Chemical products

  • H83CPD - Chemical Product Design Lecture 1 - 12

    Introduction What kinds of special products will we be designing? 3 product classes:

    Chemistry: Pharmaceuticals, Detergents, Engine oils, Lotions

    Microstructure: Inks, Paints, Ice-creams, Shampoos, Crisps

    Devices: Ink-jet cartridges, Ball-point pens, Drug delivery systems, Blood oxygenators, Nappies

  • H83CPD - Chemical Product Design Lecture 1 - 13

    An Example: Sun-block Lotion

    The sun emits both visible light and other radiation.

    Two types of rays are important: UV-A and UV-B

    UV-A 320-400nm ageing rays Skin goes brown, suntan

    UV-B 280-320nm burning rays Dilates blood vessels, skin

    goes red, sunburn

    Sunburn can lead to skin cancers!

  • H83CPD - Chemical Product Design Lecture 1 - 14

    An Example: Sun-block Lotion

    Lots of other requirements! Not just

    blocking the sun!

    Lets have a look at a real product

  • H83CPD - Chemical Product Design Lecture 1 - 15

    An Example: Sun-block Lotion

    UV-A and UV-B absorbers

    Emollients, skin softeners, moisturizers

    A,B

    A

    B A,B

    Emulsifiers

    Free radical scavengers

    pH balancers

    A,B

    A,B

    Anti-bacterial agents

    A complex microstructured chemical product!

    UV reflecter

  • Introduction The next generation of products? http://www.youtube.com/watch?v=FIIPfGC9ESk

    News: 12th January 2010

    A modified Nokia cell phone that runs on a Coca-Cola based fuel cell could run up to four times longer than a phone with a

    lithium ion battery! Crazy idea or new product???

    A mobile phone which runs on Coca-Cola???

  • Introduction The next generation of products?

    News: 20th January 2010

    A plasma jet that can replace the dentists drill???

    Researchers at Saarland University, Germany, have shown that the amount of dental bacteria can be reduced by up to 10,000-fold by firing low-temperature plasma beams at dentin, the fibrous structure beneath the tooth enamel. The team found that plasma was effective at eliminating common oral pathogens, such as Streptococcus mutans and Lactobacillus casei. 'Cold plasma is a completely contact-free method that is highly effective and pain-free.'

  • H83CPD - Chemical Product Design Lecture 1 - 18

    Value of the Chemical Product

    TAXOL

    e.g. Taxol from the bark of pacific yew tree, Taxus brevifolia, to treat Lung and Breast cancer

    240 kg bark

    5.6 kg crude extract

    2 g Taxol (each patient requires ~ 2 g / year)

    80 Trees

    Selling price 1g - $ 6000

    Annual Demand ? 200 kg

  • H83CPD - Chemical Product Design Lecture 1 - 19

    Introduction Commodity chemical

    Ex. Ethylene

    $1000/tonne

    Chemical product

    Ex. Taxol

    $6000/g

    Annual demand 200 kg

  • H83CPD - Chemical Product Design Lecture 1 - 20

    Introduction Nature of Chemical Products is different from Commodities

    So What?

    Should be Designed, Developed & Manufactured

    very differently

  • Introduction

    The use of Chemistry, Physics, Engineering, Biology

    to achieve the functions of a product

    as specified by a careful design. So it is exactly what it says on the tin!

    Use of science to develop products that fulfil

    customer needs through careful design

    What is Chemical Product Design?

  • Introduction What is Chemical Product Design?

    Need a clearer definition of product involved

  • Introduction

    What is special about Chemical Product Design?

    A combination of market awareness, design and science

    Making products that are useful to the consumer, chemically and physically viable, and profitable to

    the manufacturer

    Very different to chemical plant design we are interested in the new special functions and

    benefits of our product rather than fine-tuning and optimisation of well-established processes

  • Introduction

    What is special about Chemical Product Design?

    Often the product has a very special and complex function

    There is plenty of room for innovation! Here is your chance to be creative, in finding new solutions to

    old problems.

    We will need to learn to identify customer needs, come up with ideas, learn to select the ideas to leave

    viable products, and understand how to manufacture them.

  • Introduction Isnt Chemical Engineering about Commodity chemicals and Fuels

  • H83CPD - Chemical Product Design Lecture 1 - 26

    Introduction Historically, chemical industry dominated by commodity

    chemicals

    * Manufacture Large quantities (> 10000 tons/year)

    * Sold into Market Differentiated by Price

    * Immensely Productive & Successful

    * Major Source of Employment

    After World War II the Golden Age of chemical industry (similar to that of the modern IT industry)

    Since the 1970s, growth has slowed But Stayed Profitable?

    (a) Consolidation (b) Scale Economies

  • H83CPD - Chemical Product Design Lecture 1 - 27

    Introduction Since the 1990s, a shift to chemical products

    (a) New Resources - Devoted to Design & Dev. of

    Chemical Products

    (b) Employment of New Graduates

    Many of the old traditional

    chemical companies now

    do chemical product

    design!

    Flavours

    Skin-care products

    Coatings

    Polyester, fertilizers, ethylene

    BEFORE

    AFTER

  • H83CPD - Chemical Product Design Lecture 1 - 28

    Introduction Not just chemical

    companies, also food

    manufacturers

    Beer!

    BEFORE

    AFTER

    Guinness Extra Cold

    Simple physical change led to new

    product and increased revenues!

    Guinness Surger Ultrasound device for nucleating bubbles to

    produce a pint just like at the pub!

  • H83CPD - Chemical Product Design Lecture 1 - 29

    Introduction

    Does it mean Commodity Business Gone?

    Absolutely No

    To be made Always

    Employ relatively few people

    Often Private Companies Manage the Trade Cycle

  • H83CPD - Chemical Product Design Lecture 1 - 30

    Introduction

  • H83CPD - Chemical Product Design Lecture 1 - 31

    Introduction Chemical products Vs Commodity Chemicals

    Commodity products Chemical products

    Quantity >1,000 tons/yr

    (@ >10,000 tons/yr)

    < 1 ton/yr

    (@

  • H83CPD - Chemical Product Design Lecture 1 - 32

    Introduction Chemical products Vs Commodity Chemicals

    Commodity products Chemical products

    Research Activities

    Less Intense

    Speed of design

    Less important Very important

    Manufacturing Continuous, large scale & purpose built plants

    Batch, generic equipment

    Design team Only specialised in plant design, commissioning &

    optimisation

    An integrated team from inception to

    marketing Process Efficiency

    Very Important Not Important

  • H83CPD - Chemical Product Design Lecture 1 - 33

    Introduction Chemical products Vs Commodity Chemicals

    Commodity products Chemical products

    Energy Integration

    Important Secondary Value

    Market lifetime

    (Life cycle)

    Long Short to Medium

    Examples Ethylene, propylene, acetic acid, PVC, etc.

    Pharmaceutical & health care products, special solvent, etc.

  • H83CPD - Chemical Product Design Lecture 1 - 34

    What is CPD? Chemical Product Design (CPD):

    Emphasise decisions made before process design

    Has arisen in response to recent changes in the chemical industry

    Products must be developed, produced, applied and tested by chemical product design engineers who understand the following relationship:

    Composition

    Structure Property

  • H83CPD - Chemical Product Design Lecture 1 - 35

    Why is CPD important? 1. The change in CPI Example: rise and fall of

    textile fibres (106 lbs/year)

    1950 1970: 20% growth per year

    Fibre 1948 1969 1989

    Cotton, Wool

    4353 4285 4794

    Synthetics 92 3480 8612

    DuPont was like the Microsoft of the 1950s!

    1970 1990:

  • H83CPD - Chemical Product Design Lecture 1 - 36

    Why is CPD important? 1. The change in CPI

    Ethylene fewer players (BP Amoco, 2002)

  • H83CPD - Chemical Product Design Lecture 1 - 37

    Why is CPD important? 1. The change in CPI

    (BP Amoco, 2002)

    Plastics - fewer companies controlling more capacity

  • H83CPD - Chemical Product Design Lecture 1 - 38

    Why is CPD important? 1. The change in CPI Having exhausted in optimisation & restructuring, if

    companies are not profitable, they have three further options: Leave the chemicals business altogether Focus only on commodities Reduce the Research - Concentrate on In-House Efficiency Focus on speciality chemicals - Production in Much Smaller Volume - Bigger Profits

  • H83CPD - Chemical Product Design Lecture 1 - 39

    Why is CPD important? 2. Changes in employment Dominance of commodity chemicals eroded by emphasis on

    products

    Much less activity in commodities

    Much more activity in products and consulting

    Chemical product engineers must take a bigger picture

    Career destinations of Chemical Engineers in 1975 vs. 2000:

    Used to work mainly on

    commodities, but today more

    and more are chemical

    product designers!

    It means this may be one of the

    most important courses you will

    ever take! 1975 2000

  • H83CPD - Chemical Product Design Lecture 1 - 40

    Why is CPD important? 3. Trend in Chem Eng Skills learned by Chemical Engineers (Always Diverse)

    Do not need major changes to be useful for products !!

  • H83CPD - Chemical Product Design Lecture 1 - 41

    Why is CPD important? 3. Trend in Chem Eng

    (NSF, 2003)

  • H83CPD - Chemical Product Design Lecture 1 - 42

    Changes in corporate culture 1. Corporate organisation 1. Functional organisation

    Each division have different responsibilities

    Work like chemical reaction in series

    Can be effective, but slow (e.g. marketing talks to research, rarely to engineering)

    2. Project organisation A team of different division

    Work like parallel reaction, with synergy between function

    Fast product development much better for products !!

  • H83CPD - Chemical Product Design Lecture 1 - 43

    Changes in corporate culture 2. Corporate strategy 1. Market pulled companies:

    More Common

    Look toward their markets for inspiration Design of products is driven by the NEEDS of the consumer

    MARKET FORCES dictate what products are wanted and viable

  • H83CPD - Chemical Product Design Lecture 1 - 44

    Changes in corporate culture 2. Corporate strategy 1. Market pulled companies:

    Make breakfast cereal

    Company saw the (market) need for healthy energy-drinks

    Released K20 protein water in August 2007

  • H83CPD - Chemical Product Design Lecture 1 - 45

    Changes in corporate culture 2. Corporate strategy 1. Market pulled companies:

    More Common

    Make climbing equipment

    Company saw the bigger market in raincoats!

    Can sell more raincoats than ice-picks!

  • H83CPD - Chemical Product Design Lecture 1 - 46

    Changes in corporate culture 2. Corporate strategy 2. Technology pushed companies:

    Less Common

    Design of products is driven by the new

    emerging science and technology

    Need to be creative to think of

    applications!

    1938 PTFE discovered 1954 Way of attaching PTFE to Aluminium discovered Lots of other applications low friction, insulator, chemically inert Challenges because it is difficult to process!

  • H83CPD - Chemical Product Design Lecture 1 - 47

    Changes in corporate culture 2. Corporate strategy 2. Technology pushed companies:

    Less Common WL Gore make Goretex breathable film for high

    quality raincoats

    Developed technology to make expanded PTFE

    Properties Microporous Good strength Chemical inertness Biocompatibility High thermal resistance High chemical resistance in harsh

    environments

    Low flammability Low coefficient of friction Low dielectric constant Low water adsorption Good weathering properties

    SEM 40,000x

  • H83CPD - Chemical Product Design Lecture 1 - 48

    Changes in corporate culture 2. Corporate strategy 2. Technology pushed companies:

    Textiles

    Coatings Filtration

    Hi-tech fibers Medical implants

    Company has expanded into a very wide range of markets

  • H83CPD - Chemical Product Design Lecture 1 - 49

    Changes in corporate culture 2. Corporate strategy 2. Technology pushed companies:

    Textiles

    Company has expanded into a very wide range of markets

    Company does not make raincoats, however They simply sell their hi-tech fabric to raincoat maufacturers

  • H83CPD - Chemical Product Design Lecture 1 - 50

    Changes in corporate culture 2. Corporate strategy 2. Technology pushed companies:

    Less Common

    Extend existing technology & services Exxon Mobil knowledge of

    petrochemical reactions used to develop new catalysts

    Astra Zeneca experience in injectable therapeutics for drug delivery (www.astrazeneca.com)

  • H83CPD - Chemical Product Design Lecture 1 - 51

    Changes in corporate culture 2. Corporate strategy

    (Wei, 2007)

    HISTORIC INNOVATIONS

    Began with High Market need

    But with Low Technological Capability

    Began with Low Market Identification

    But with High Technological Capability

  • H83CPD - Chemical Product Design Lecture 1 - 52

    Product Life Cycle Spring Pioneer Tissue Engg

    Introduce an Innovative Product

    Great Potential Creating a New Market

    Great Risk - Bold introduction of New Technology

    Summer Fast Follower Inkjet and Toner

    Successful New Product and so New Market Introduced by A

    Generates many fast followers to introduce me-too products with better properties (Wei, 2007)

  • H83CPD - Chemical Product Design Lecture 1 - 53

    Product Life Cycle Autumn Cost Cutter -

    Gasoline A mature product in an

    established market

    Innovation pace - Slow

    Limited opportunities to Improve in order to cut costs

    Winter Caretaker Sulfuric acid A Declining product

    Caretakers prevent Obsolescence

    (Wei, 2007)

  • H83CPD - Chemical Product Design Lecture 1 - 54

    CPD procedure Consider three chemical products:

    Pollution-preventing ink

    Amine to scrub acid gases

    Ventilator for well-insulated house

    Q: what do these all have in common?

    Answer: the way they are designed

    Design Procedure:

    Define the product need

    Find ideas to meet the need

    Select the best ideas

    Decide on product & its manufacture

  • H83CPD - Chemical Product Design Lecture 1 - 55

    CPD procedure a glimpse Four main steps:

    Needs What needs should the product fulfill? Need a Benchmark (Standard for comparison)

    Selection of Benchmark Existing product or Ideal

    Needs (Qualitative) translated to Specifications (Quantitative)

    Define as well as possible Specifications become Definitive

    Ideas What products could satisfy these needs? Search for a large number: Brainstorming, Synthesize

    many compounds

    Screening of the Ideas Based on Objectives

  • H83CPD - Chemical Product Design Lecture 1 - 56

    CPD procedure a glimpse Selection Which ideas are most promising?

    Large number of Fragmentary ideas ( ~ 100)

    Make a Shortlist or Do the reduction by a factor of 20 (100 5)

    Select 1 or 2 for further design and development

    Normally the final 2 ideas are not comparable

    Apply Risk Management

    Manufacture How do we make products in commercial quantities? Use Batch & Generic equipment

    Cost Estimation

  • H83CPD - Chemical Product Design Lecture 1 - 57

    CPD procedure

    All these are totally different from Traditional Chemical Engineering

    EXCITING

    Traditional chemical engineering Product Engineering

    Processes Molecular-level design

    Commodities Added value products

    Macro-scale engineering Molecular scale engineering

  • H83CPD - Chemical Product Design Lecture 1 - 58

    CPD procedure At the start of the procedure

    When we decide What the Product Should Do?

    We expect a Major Input - * Marketing & Research

    * Engineering

    At the end of the procedure

    When we reach the Manufacturing stage

    We expect a Major Input - * Engineering

    Reduced Role - * Marketing & Research

  • H83CPD - Chemical Product Design Lecture 1 - 59

    CPD Procedure Controversies

    Good to Review the controversies

    To prepare ourselves for EXCEPTIONS AND DIVERSIONS

    1. The four-step procedure is not general

    it is clearly a simplification

    it is unlikely that real product design will be a simple, sequential procedure, and iteration between the steps is needed

    2. Management, not technology, is the key!

    Implication: technology is always available, if only managers/engineers do their job properly

  • H83CPD - Chemical Product Design Lecture 1 - 60

    CPD procedure controversy 3. The subject is already covered as part of process design

    CPD goes beyond this process design hierarchy

    The last step of CPD (manufacturing) includes all of the process design hierarchy

    Focus on the initial decision around the choice of the product and de-emphasise its manufacturing

    Shift away of our daily bread & butter engineering calculation

    Process design (Douglas, 1988) Product design

    Batch vs. continuous process Identify customer needs

    Inputs and outputs structure Generate ideas to meet needs

    Reactors and recycles Select among ideas

    Separations and heat integration Manufacture product

    CPD is not just engineering, must also concentrate on business and technology!

  • H83CPD - Chemical Product Design Lecture 1 - 61

    Conclusions CPD is a procedure where

    Customer Needs

    Commercial Products

    Valuable for specialty

    chemicals

    Management/senior

    management involvement:

    product design >> process

    design

  • H83CPD - Chemical Product Design Lecture 1 - 62

    Conclusions Types of decisions involved in product design and

    development

    Product design decisions

    Process design decisions

    Business decisions

    Management decisions

    An approach (paradigm) for product design and development is

    needed to organize the activities and tasks in a systematic

    manner

    More case studies are needed

    Technologies behind different products are important

    : What to make?

    : How to make?

    : Do we want to make?

    : How to do it efficiently?