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    BIO 15: Survey of Anatomy and

    Physiology

    Spring 2010

    Instructor: Leslie Bach

    Outline

    Course introduction

    Levels of organization

    Body regions

    Planes and sections

    Body cavities

    Abdominopelvic quadrants

    Homeostasis

    Introduction

    Syllabus

    Course outline

    Lab sections

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    Anatomy and Physiology

    Anatomy the structure (morphology) of the

    body and its parts

    Physiology the functions of these parts of

    the body

    Anatomy and physiology are closely

    interrelated because the function of a part

    depends on its structure

    Anatomy Terms

    Anatomy Terms

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    Anatomy Terms

    Bilateral paired structures, one on each

    side of the body

    Ipsilateral structures on the same side of

    the body

    Contralateral structures on opposite sides

    of the body

    Superficial near the surface

    Deep more internal

    Planes and Sections of the Body

    Levels of Organization

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    Levels of Organization Atoms are the simplest level

    Two or more atoms comprise a molecule

    Macromolecules are large, biologically importantmolecules inside cells

    Organelles are aggregates of macromolecules usedto carry out a specific function in the cell

    Cells are the basic unit of life

    Tissues are groups of cells functioning together

    Groups of tissues form organs

    Groups of organs function together as organ systems

    Organ systems functioning together make up anorganism

    Organization of the Body

    Major features of the human body include:

    Body cavities

    Membranes

    Organ systems

    Body Cavities

    The body is divided into two portions Appendicular portion upper and lower limbs

    Axial portion head, neck and truck

    The axial portion includes a dorsal and

    ventral cavity

    Organs within the ventral cavity are called viscera

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    Body Cavities

    Dorsalcavity

    Body Cavities

    The dorsal cavity includes:

    Cranial cavity

    Vertebral canal

    The ventral cavity includes:

    Thoracic cavity

    Divided into right and left halves by the mediastinum

    Abdominopelvic cavity

    Divided into the abdominal cavity and pelvic cavity

    Thoracic and Abdominopelvic Membranes

    The thoracic cavity is lined with pleura Parietal pleura lines the cavities

    Visceral pleura covers the lungs

    The heart is surrounded by pericardium Visceral pericardium covers the heart

    Parietal pericardium makes up an outer sac

    The abdominopelvic cavity is lined withperitoneum Parietal peritoneum lines the cavity wall

    Visceral peritoneum covers the organs

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    Abdominopelvic Quadrants

    The

    abdominopelviccavity can bedivided into four

    quadrants

    Abdominopelvic Regions

    The abdominopelvic

    cavity can also bedivided into nineregions

    Eleven Systems of the Body

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    Body Covering

    Integumentary system skin, hair, nails, and

    various glands

    Covers the body, senses changes outside the

    body, and helps regulate body temperature

    Support and Movement

    The skeletal system made of bones,

    cartilage, and ligaments

    Supports, protects, provides framework, stores

    inorganic salts, and houses blood-forming tissues

    The muscular system made of skeletal

    muscles

    Provide body movement, posture, and body heat

    Integration and Coordination

    The nervous system the brain, spinal cord,nerves, and sense organs

    Integrates information incoming from receptors

    and sends impulses to muscles and glands

    Sends fairly short-term messages to cells

    The endocrine system all of the glands that

    secrete hormones

    Integrates metabolic functions

    Sends long-term messages to target cells

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    Transport

    Cardiovascular system the heart, blood

    vessels, and blood

    Distributes oxygen and nutrients throughout the

    body and removes wastes from the cells

    Lymphatic system lymphatic vessels, lymph

    nodes, thymus, and spleen

    Drains excess tissue fluid and includes immune

    cells

    Absorption and Excretion

    Digestive system mouth, esophagus,stomach, intestines, and accessory organs Receives, breaks down, and absorbs nutrients

    Respiratory system lungs andpassageways Exchanges gasses between the blood and air

    Urinary system kidneys, ureters, bladder,urethra Removes wastes from the blood and helps to

    maintain water and electrolyte balance

    Reproduction

    Reproductive system - produces neworganisms

    Male reproductive system testes, accessory

    organs, and vessels that conduct sperm throughthe penis

    Female reproductive system ovaries, uterinetubes, uterus, vagina, and external genitalia

    Also houses the developing offspring

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    Homeostasis

    Homeostasis maintaining the internal environment

    Homeostasis

    Changes at the cellular level occur due to

    external and internal variables, but are kept

    relatively small

    Stability due to coordinated physiological

    processes

    Homeostasis

    All of the chemicals, molecules, andmacromolecules needed are regulated by

    homeostatic mechanisms

    Keeps the balance between intake of the

    substance and its loss by metabolism or excretion

    Factors such as temperature, energy, bloodpressure, and pH are also regulated

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    Homeostasis

    Negative feedback systems

    An increase or decrease in the variable being

    regulated brings about responses that tend tomove the variable in the opposite direction of the

    original change

    A decrease in body temperature responses

    that increasebody temperature

    Most common homeostatic mechanisms

    Homeostasis

    Homeostasis

    Negative feedback loops are self-correcting

    Over time, responses will naturally come toequilibrium

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    Homeostasis

    Feedforward regulation Anticipates changes in a regulated variable

    Improves the speed of homeostatic responses

    Reduces changes in the regulated variable

    Example: External temperature lowers Nerve sensors in the skin sense the change in

    temperature

    Homeostatic response is triggered to conserveand increase temperature before internaltemperature changes significantly

    Homeostasis

    Circadian rhythms

    Not just about sleeping; rhythms exist for most

    biological processes

    Can provide some measure of predictive control

    of homeostatic mechanisms

    Sets up certain systems to be prepared when a

    challenge is most likely

    Homeostasis

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    Homeostasis

    Positive feedback systems

    An initial disturbance to a variable leads to

    responses that increase the disturbance

    Does not favor system stability

    Homeostasis

    Positive feedback systems amplify the change fromthe normal

    If thermoregulation used positive feedback, wewould get hotter in hot weather and colder in coldweather

    Homeostasis

    Examples of positive feedback systems: Blood clotting

    Activated platelets release chemicals to activate moreplatelets

    Breast milk production

    Nursing releases hormone cascades that result in

    increased milk production

    Contractions in childbirth

    Oxytocin is released during contractions, whichstimulates more contractions at increased strength andfrequency

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    Homeostasis

    Acclimatization

    The process of adapting to environmental stress

    by prolonged exposure to that stress

    Sometimes reversible, sometimes irreversible

    Developmental acclimatization during the developmentof certain structures or responses can lead toirreversible changes

    Homework 1

    1. Define homeostasis.

    2. Explain the control of body temperature.

    3. Explain the difference between the axial and

    appendicular portions of the body.

    4. Sketch the outline of a human body, and use linesto indicate each of the following sections:

    Sagittal Transverse

    Coronal

    Next Lecture

    Lecture topic: Chemistry Atomic structure

    Chemical bonds

    Chemical formulas

    Chemical reactions

    Textbook chapter: 2