Learning Set 2: Lesson 2
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Transcript of Learning Set 2: Lesson 2
Cell Activity Videos
Learning Set 2 : Lesson 2 : Slide 1 Optional
1) Plant Cells
2) Mitosis
3) Phagocytosis
4) Listeria
5) Neutrophil
6) Exocytosis
7) Bacteria
Meiosis
Mitosis 2
Mitosis 3
Exocytosis 2
Exocytosis 3
Bacteria 2
Additional Videos
Where are proteins in our bodies?
Testing for Protein
Where are proteins in chicken parts?
Part being tested Prediction – Is protein
present?
Result – Is protein present?
Mixing solution without any
chicken
skin
liver
muscle
fat
bone
feather
Learning Set 2 : Lesson 2 : Slide 1
Special Skin Cells Make Melanin
body
epidermis
How is melanin made inside the melanocytes?
epidermis
melanocytes
tissue
cells
Melanosomes- organelles containing melanin found in melanocytes and other skin cells.
Learning Set 2 : Lesson 3 : Slide 2
Other skin cells
Melanocyte
Learning Set 2 : Lesson 3 : Slide 3
Melanin (black dots) taken up by skin cells called keratinocytes
“Octopus
” like
arms of
Melanocyte
cell
Other skin cells
Looking inside a melanosome
Large protein molecule called Tyrosinase. It is special type of protein that assists
chemical reactions in the body.
Learning Set 2 : Lesson 3 : Slide 4
Other skin cells
Looking inside a melanosome
OxygenTyrosine- small
molecule. Building block needed to build melanin.
First step in making melanin:Reaction between two molecules, one tyrosine and one O2 to make a new molecule (called DOPA)
O O
Learning Set 2 : Lesson 3 : Slide 5
Other skin cells
•
OxygenTyrosine
O O
How can a large protein molecule like the Tyrosinase help to start the chemical reactions that form melanin?
Tyrosinase
Learning Set 2 : Lesson 3 : Slide 6
Other skin cells
Tyrosinase helps to position the molecules so that they can react.
Learning Set 2 : Lesson 3 : Slide 7
Tyrosinase(protein)
Skin cell
•
nuc
New Molecule
O
Other proteins help turn the new molecule (called DOPA) into melanin.
Learning Set 2 : Lesson 3 : Slide 8
Other skin cells
What happened to Sammy Sosa?
Learning Set 2 : Lesson 3 : Slide 9
Ponds Skin Lightening Cream
What is the message of this ad?
www.advertolog.com/ponds-5419455/print-outdoor/swan-7423605/
Learning Set 2 : Lesson 3 : Slide 10
Lactose intolerance
• Cannot break down lactose, a sugar found in dairy products
• Instead, bacteria in the intestine break down the lactose, producing gas
• Most children can break down lactose
• Most adults in the world cannot break down lactose - making them lactose intolerant
Learning Set 2 : Lesson 4 : Slide 11
Cells in Small IntestineBreak Down Lactose
intestine cells
How is lactose broken down in intestine cells?
small
intestine
Lactose
from diet
Lactose
brought
into
intestine
cells
Lactose
broken
down
Learning Set 2 : Lesson 4 : Slide 12
Looking inside small intestine cells
Small intestine cells
lactose
galactose glucose
Learning Set 2 : Lesson 4 : Slide 13
Looking inside small intestine cells
Small intestine cells
lactoselactase
How does the shape
of the large protein
molecule Lactase
help the chemical
reaction that forms
glucose from
lactose?
Learning Set 2 : Lesson 4 : Slide 14
Looking inside small intestine cells
Small intestine cells
galactose
glucoselactase
Learning Set 2 : Lesson 4 : Slide 15
Lactose intolerance? Is it really an illness or are we victims of false
advertising?
inventorspot.comwww.pcrm.org/newsletter/jun05/milk_ad
.html
Learning Set 2 : Lesson 4 : Slide 16
Learning Set 2 : Lesson 6 : Slide 17
Cartoon Model Space-filling Model Backbone Model
Protein Models
PROTEIN STRUCTURE
A protein
Learning Set 2 : Lesson 6 : Slide 18
Learning Set 2 : Lesson 6 : Slide 19
PROTEIN STRUCTURE
When amino acids
form a long chain, the
chain folds and makes
a protein. The amino
acids cause the
protein to twist and
bend, as shown on
the left.
Amino Acid Chain
Chain of amino acids folded into a protein.
Learning Set 2 : Optional Lesson: Slide 20
ESSENTIAL AMINO ACIDS
Adapted from Carolina Supply Company
Circle that portion of each molecule that is the same in every molecule.
Learning Set 2 : Optional Lesson: Slide 21
BASIC STRUCTURE OF AN AMINO ACID
Basic structure of an amino acid
Learning Set 2: Optional Lesson: Slide
22
AMINO ACID STRUCTURE
ALANINE
Learning Set 2: Optional Lesson: Slide 23
Chemical Structure: Chains and Rings
Tryptophan
Learning Set 2 : Lesson 7 : Slide 24
ASSEMBLY OF AMINO ACIDS
Learning Set 2 : Lesson 7 : Slide 25
Protein Models…again
Learning Set 2 : Lesson 7 : Slide 26
Key to Toobers
Red = positive charge (+)
K, R, H
Yellow = negative charge (-)
D, E
Green = hydrophobic
A, V, L, I, P, M, F, W
Blue = hydrophilic
G, S, T, N, Q, Y
Learning Set 2 : Lesson 7 : Slide 27
Toober Model (Step 1)
Learning Set 2 : Lesson 7 : Slide 28
Lactase Amino Acid Sequence
Learning Set 2 : Lesson 8 : Slide 29
Preparing a Gel
Image from powerful microscope
gel
Holes for samples
to be tested
Learning Set 2 : Lesson 8 : Slide 30
Put Protein Sample in Holes
Pipet with
solution of
proteins
Lots of different
sized proteins
Learning Set 2 : Lesson 8 : Slide 31
Samples We Want to Test
lactase
tyrosinase
Learning Set 2 : Lesson 8 : Slide 32
Adding Electricity to the Electrodes
Negatively charged
proteins move
towards positive
electrode
Learning Set 2 : Lesson 8 : Slide 33
Proteins Move Based on Size
lactase
tyrosinase
Learning Set 2 : Lesson 8 : Slide 34
Record Data with a Picture
Learning Set 2 : Lesson 8 : Slide 35
Lactase Sample for 3 Different People
Lactose intolerance:
1) No
2) ???
3) ???
Should person 2 drink
milk? Person 3? Explain
your reasoning.