LDC-CEVA Cevac IBird

April 2015

1. Presentation of LDC group

2. French Infectious Bronchitis epidemiology

3. Actions

4. Monitoring implementation

5. Results

CONTENT

A Group present in every poultry region in

France

Brittany 10 sites

1 700 employees

500 farmers

Pays de Loire / Centre / Normandy 35 sites

9 600 employees

3 500 farmers

Aquitaine 2 sites

250 employees

100 fermers

South-East 13 sites

2600 employees

1000 farmers

Paris 2 sites

250 employees

LDC - Overview

Production sites in poultry production areas : Brittany,

Loire Valley, Normandy, Burgundy, Aquitaine,…

LDC - The Group Organization

Poultry Division

Slaughterhouses

France

Upstream France

Convenience

Division

International Division

POLAND

SPAIN

International

(group Export)

Direction : Gilles HUTTEPAIN

LDC - Group Organization

Eggs

Poultry

Grain Collect

Poultry

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LDC – Group organization – The Products

Upstream Division

Turnover 610 M€ Number of farmers 1 440

Surface 1 970 000 m²

Production of poultry In front of the Group needs

70 % Chicken

15 % Label rouge chicken

60 % Turkey

50 % Duck

40 % Guinea fowl

Tons Feed /year

Poultry 780 000 T

From which processed

700 000 T

Collect Cereals/year

178 000 T

Eggs/boxes/year

325 millions eggs

Label Rouge,

Free range,

& Organic

150 millions eggs

Standards

475 millions eggs

From which 50% under

brands

Loué & Le Gaulois

Direction : Denis LAMBERT

LDC Sablé+ CEPA

Cavol

LDC - The Group Organization

Turnover : 2,1 Bn €

Volume : 460 000 T

Mix customers Retail / HD 67 %

Prof & Indust 25 %

EXPORT 8 %

Mix Product Poultry /week

2 500 000 Standard chickens 150 000 Guinea fowls

1 000 000 Label chickens + Org 104 000 Rabbits

340 000 Certified chickens 300 000 Quails

390 000 Turkeys 40 000 Squabs

315 000 Ducks

Further-processed products

1 500 T per week

LDC - The group Organization – The Products

Poultry division France

Poultry

Red Label Poultry

Cut ups

Further processed

Convenience

LDC - Our Strategy : Innovations and Brands for a strong organic growth

Poultry and convenience : synergy and complementarity

in offers

French Infectious bronchitis epidemiology

% of broiler production per department

830 million broilers 43 million layers 45 millions turkeys 120 million ducks ….Multi species production Infectious bronchitis viruses are circulating.

Need for a good viral protection

French Infectious bronchitis epidemiology

IB Mass

Strain

(Hatchery)

IB Variant Strain

(Field vaccination)

793B/QX

GUMBORO

D0 D10-D14 D16-D20

Vaccination with

Mass vaccine is

done on 100 % of

the birds, at the

hatcheries.

Field boosting with either 793 B or QX are

applied according to veterinarian, integration

or farmer decision related to IB perceived

pressure or type of broilers produced (big

birds).

=> Vaccination at the hatchery is not perceived as critical

by the independant hatcheries

=> Field vaccination is usually applied by spray with no

regular monitoring.

Need for LDC

-to get better control of vaccine & protection on the

production.

-to get better evaluation of epidemiological situation in

real time

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French Infectious bronchitis epidemiology

Actions : a new vaccination program

IB Mass Strain

+ IB Variant strain

(Cevac IBird).

Hatchery

GUMBORO

D0 D16-D20

Big birds

Certified birds

HATCHERY IB

Vaccination.

Monitoring

Implementation

Actions

3 different slaughterhouses

Vaccination Mass & Cevac IBird spray day 1

230 different poultry houses In 2 regions from nov 14.

Control of spray equipment & CHICK Program implementation

7 different hatcheries

Monitoring of day 10 PVR & respiratory signs during growing period

3 different organisations

Monitoring implementation

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Sampling &

Analysis for

epidemiological

monitoring

10 Blood samples per flock : Biocheck Elisa

Cecal tonsils: frozen and PCR analysis

according to Elisa & farm results

3 different slaughterhouses

Vaccination Mass & Cevac IBird spray day 1

230 different poultry houses In 2 regions from nov 14.

Control of spray equipment & CHICK Program implementation 7 different hatcheries

Monitoring of day 10 PVR & respiratory signs during growing period

5 different organisations

Desvac In-Line sprayer

Desvac In-Line sprayer

Hatchery spray evaluation

Results :

Safety

1 out of 230 flocks with

mortality before 10 days,

after veterinarian visit it was

due to E coli infection

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Results : IB ELISA MEAN TITERS

Results : IBV mapping

October-December 2014, 28% of the farms are challenged by a field virus (T> 3000)

No vaccination< 500 1000< « normal »< 3000 Doubtfull > 3000, high CV

Field infection > 3000, low CV

Results : IBV mapping

December 14 – February 15 , 38% of the farms are

challenged by a field virus (T> 3000)

No vaccination< 500 1000< « normal »< 3000 Doubtfull > 3000, high CV

Field infection > 3000, low CV

Results :

Some respiratory signs after 10 days in 9 out of

230 flocks :

• 1 IB titers OK

• 1 positive for ORT

• 1 positive for MS

• 2 IB PCR >0 no identification possible

• 4 IB PCR >0 for IBird, no conclusion other

cause ?

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Conclusion

Hatchery vaccination with Mass & Cevac IBird gave

consistent seroconversion at slaughter

It can be used as hatchery vaccination monitoring

Hatchery spray application was improved with equipement

setting & control

Field virus circulation was detected between 28 % and 38%

of the farms according to the period.

Reinforced the need of a complete and well applied

vaccination program in our production area.

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