LABORATORY ANIMAL SCIENCE · 3/5/09! 16! Some milestones using animals 1902 understanding of...
Transcript of LABORATORY ANIMAL SCIENCE · 3/5/09! 16! Some milestones using animals 1902 understanding of...
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LABORATORY ANIMAL SCIENCE MODULE 1 IN FELASA C COURSE / MEDVET1
Aurora Brønstad, Chief veterinarian, The Animal Facilities of, University of Bergen JANUAR 15-16-09!
Introduction
Practical information about the course Definition of laboratory animal science Use of animal in Science in Norway Lab animals and ethics Lab animals and media AIM
http://www.uib.no/dyreavd/kurs-jan-09.htm
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Practical information
Dyreavdelingenes web site http://www.uib.no/dyreavd/
Information to participant on http://www.uib.no/dyreavd/kurs-jan-09.htm
Compendium: You do not need it for the first module 1 You need it for the exam in march
MEDVET 1 (master students): Exam after the course
FELASA-C/B Exam in march
Pract inf. cont.
FELASA C course Lectures march 2009 Exam (Written exam) “hjemme eksamen”
finished end of the course Practical part: 3 days within March 2009
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WHY DO YOU HAVE TO TAKE THIS COURSE ???
§13 Planning and conducting an experiment.
“Persons who conduct or plan experiments must have received a form of training approved by the Mattilsynet”
(Regulation on Animal Experimentation)!
Compulsory training
The approved competent person (”ansvarshavende”) is responsible for ensuring that all personnel have the necessary training.
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FELASA categories A Animal care personnel* B Research technicians C Researchers/scientists D Laboratory animal specialists*
*profesionals: life-long learning program
Compulsory education - researchers
“FELASA C” Theoretical part: 5 days/35 hours Practical training: 3 days/ 21 hours Self study and exam: 24 hours
MEDVET1 Covers 12 of 35 hours theoretical part
FEDERATION OF EUROPEAN LABORATORY ANIMAL SCIENCE ASSOCIATIONS!
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http://www.uib.no/dyreavd/kurs.htm
UoB concept based on modules
Practical part - 3 days
Aimed to be suited to the species
Relevant techniques you work with
Signed ”praksisattest” by manager/supervisor
Start now finalize before exam
Can also be obtained at “Dyreavdelingene”, contact [email protected]
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http://www.uib.no/dyreavd/kurs-jan-09.htm
”Handouts”
All handouts can be downloaded from http://www.uib.no/dyreavd/kurs-jan-09.htm
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Lunch
1200-1300 You can have lunch in the cantina on the hospital or in the
BBB building.
Laboratory animal science
Definition: Multidisciplinary branch of science, contributing to the humane
use of animals in biomedical research and to the collection of informative unbiased and reproducible data.
(Principles of laboratory animal science, L.F.M. van Zutphen, 2001)
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Laboratory animal science (LAS) Includes: Laws, regulations and laboratory animal ethics. Characteristics of animals: anatomy, physiology, genetics
and biochemistry. Influence of environmental factors on experimental
results. Laboratory animal procedures and research design.
The three R’s
Reduction Refinement Replacement (Russel & Burch, 1959)
Implemented in !planning &!performing !experiments !
using animals!
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Russel & Burch
“the greatest scientific achievements have alway been the most humane and the most aesthetically attractive, conveying that sense of beauty and elegance which is the essence of science at its most successful”
The principal of humane experimental techniques - 1959
Animals used in Norway 2006
≈48 000 Mice and rats
≈ 600 000 fish
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Animals used in Norway 2007
41 000 mice & rats
1 128 pigs 3 320 000 fish
Animals used at Vivarium 2007
728 mice 299 rats 104 pigs
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Lab animals (ex fish)
Ca 120 000 i 1982 - 50 000 i 2006
Fish Ca ”0” i 1982
2 000 000 in 1986 650 000 in 2006
Mice Ca 70 000 in 1982
35000 in 2006
Rats Ca 25 000 in 1982
13 000 in 2005
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Is it ethical to use animals in research?
Is it ethical not to use animals in research ?
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Animal experiments and media
Ethical guidelines
Shows direction and ethical solutions Humans are personally responsible actors
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Carrols Corporate Social Responsibility (CRP) - pyramid
Ethics vs moral
When you have a problem and do not know what to do - then you have an ethical problem
If you have a problem and know what you should do, but don't do it, then you have a moral problem
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Summary 1/2
Knowledge on regulatory demands for education of personnel involved in laboratory animal research (theory part, practical part and exam)
Know the different FELASA categories for education of lab animal personnel
Practical information – where to find handouts and teaching material
Summary 2/2
Know the definitions of Laboratory animal science Knowledge of the 3R Knowledge of number of animals used in research in
Norway Reflection on Ethical questions Reflection on public relations and media
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Some milestones using animals
1902 understanding of malaria life cycle pigeon 1905 study of mechanism of tuberculosis cow, sheep
1936 understanding of chemical signal transmission in nerved cat, frog, bird
1943 understanding of the role of Vitamin K rat, mice, dog chicken
1945 understanding of the curative effect of penicillium in infectious disease mice
1954 polio vaccine virus and development of vaccine monkey, mice
1966 tumor inducing virus and hormonal treatment of cancer rat, rabbit, chicken
1990 organ transplantation techniques dog
Laboratory animal science
Definition: Multidisciplinary branch of science, contributing to the humane
use of animals in biomedical research and to the collection of informative unbiased and reproducible data.
(Principles of laboratory animal science, L.F.M. van Zutphen, 2001)