Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections...
Transcript of Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections...
![Page 1: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/1.jpg)
SURGICAL INFECTION
Kirati Watcharachan MD.
Department of Surgery
Faculty of medicine Chiangmai University
![Page 2: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/2.jpg)
GENERAL CONSIDERATIONS • Surgical infections : infections that require operative
treatment or result from operative treatment.
• Infections that require operative treatment include 1. necrotizing soft tissue infections.
2. body cavity infections such as peritonitis, suppurative pericarditis, and empyema.
3. confined tissue, organ, and joint infection such as abscess and septic arthritis.
4. prosthetic device–associated infections.
![Page 3: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/3.jpg)
• Infections that result from operative treatment
include
Wound infection,
Postoperative abscess. Postoperative ( tertiary ) peritonitis,
Other postoperative body cavity infection, Prosthetic device–related infection,
Other hospital-acquired infections :
pneumonias, urinary tract infection, and vascular
catheter–related infection.
GENERAL CONSIDERATIONS
![Page 4: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/4.jpg)
• Host defenses and antibiotic therapy are adequate to overcome most infections.
• Operative treatment :
Host defenses cannot function properly.
Continuing contamination with microorganisms:
Infected fluid collections.
Infected necrotic tissue.
Infected foreign bodies.
Principles of Therapy GENERAL CONSIDERATIONS
![Page 5: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/5.jpg)
• Development of surgical infection depends on :
1. Microbial pathogenicity and number
2. Host defenses
3. Local environment
4. Surgical technique ( for postoperative infection ).
Determinants of Infection GENERAL CONSIDERATIONS
![Page 6: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/6.jpg)
• Local Host Defenses
A layer of epithelium
Skin : multilayered, the superficial layers are keratinized.
Nasopharynx, oral cavity, esophagus, and genitourinary tract .: multilayered
The flushing action of tears and urine, cilia ( trachea, bronchi), peristalsis, mucus, pH (gastrointestinal tract), and local immunity (IgA).
Host Defenses
Determinants of Infection GENERAL CONSIDERATIONS
![Page 7: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/7.jpg)
• Systemic Host Defenses
A complex system of defense mechanisms exists throughout the body that can inactivate and kill microbial agents. Consist of :
Phagocytic cells.
Immune system.
Other molecular cascades : complement system, coagulation system, kinin system.
Determinants of Infection Host Defenses
GENERAL CONSIDERATIONS
![Page 8: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/8.jpg)
• Inhibit systemic host defenses from being fully effective. Devitalization of tissue Foreign bodies Fluid collections and edema Peripheral vascular disease Shock The lowered PO 2 : inhibits phagocytosis and promotes the
growth of anaerobes.
Local Environmental Factors
Determinants of Infection GENERAL CONSIDERATIONS
![Page 9: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/9.jpg)
Handling tissues gently;
Removing devitalized tissues, blood, and other substances
that promote the growth of microbes.
Using drains appropriately.
Avoiding excessive cautery.
Not performing intestinal anastomoses under tension.
Surgical Technique
Determinants of Infection GENERAL CONSIDERATIONS
![Page 10: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/10.jpg)
TYPES OF SURGICAL INFECTIONS
![Page 11: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/11.jpg)
SOFT TISSUE INFECTIONS
![Page 12: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/12.jpg)
IMPETIGO • Disease limit at epidermis
• 2 separated clinical forms
1. Bullous impetigo
2. Epidermal impetigo
![Page 13: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/13.jpg)
BULLOUS IMPETIGO
![Page 14: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/14.jpg)
EPIDERMAL IMPETIGO
![Page 15: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/15.jpg)
![Page 16: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/16.jpg)
IMPETIGO • Diagnosis
Identify organism by aspiration fluid in vesicle for Gram stain : S. aureus or streptococcal morphology
• Treatment
Improve hygiene
Remove crust with soap and water
Topical antibiotic
![Page 17: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/17.jpg)
ERYSIPELAS • Superficial infection of the skin with extensive
lymphatic involvement
• Almost always due to Streptococcus pyogenes and
other streptococcus
• Infants , children , elderly : most common
Pre-existing lymphatic obstruction , edema from LN
dissection
![Page 18: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/18.jpg)
ERYSIPELAS • Clinical manifectration
Pain , swelling , well demarcated margin
Fever , Leukocytosis
Not invade through dermis
Frequently occur beside the nose and cheek
Elephantiasis-like syndrome in chronic case :
from chronic lymphatic obstruction
![Page 19: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/19.jpg)
ERYSIPELAS • Treatment
Antibiotic : Penicillin group.
In extensive case : admit , Parenteral
antibiotic
![Page 20: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/20.jpg)
![Page 21: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/21.jpg)
![Page 22: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/22.jpg)
CARBUNCLE • Confluent infection of multiple contiguous follicles , the
infection is limited to the subcutaneous tissue by thick
overlying skin and dense subcutaneous fascia.
• Cause from S. aureus
• Begin as furuncle on the back of neck , axilla , or pubic
region then spread into adjacent follicle and penetrate to the
subcutaneous result in abscess with multiple tract
![Page 23: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/23.jpg)
CARBUNCLE • Clinical : look sick , high fever , pain and swelling of
skin overlying carbuncle
• Always treated with antibiotic and I&D.
cruciate incision on the abscess
Dissect under the flap for adequate drainage
• May be recurrent
![Page 24: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/24.jpg)
![Page 25: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/25.jpg)
Hidradenitis Suppurativa • Inflammation disease of the apocrine gland - bearing
area.
• Chronically , relapsing nature.
• Rare before puberty ( apocrine gland do not reach
functional status until the age of puberty )
• Most common : axilla
![Page 26: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/26.jpg)
![Page 27: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/27.jpg)
Hidradenitis Suppurativa • Pathophysiology
![Page 28: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/28.jpg)
![Page 29: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/29.jpg)
![Page 30: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/30.jpg)
• Medical therapy in acute stage : symptomatic relief and
control of local infection, broad spectrum antibiotic , good
personal hygiene , avoidance of tight-fitting cloth , drainage.
• The most effective treatment : surgical management
Adequate excision of disease skin and adjacent apocrine
gland bearing tissue.
Cover the defect by split thickness skin graft (STSG)
• Treatment
![Page 31: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/31.jpg)
![Page 32: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/32.jpg)
CELLULITIS • An acute expanding infection of the skin and subcutaneous
tissue characterized by warm , erythema and edema.
• Streptococcus pyogenes , staphylococcus aureus , other Gm
positive pyogenic cocci ( such as S. Pneumoniae ) and Gm
negative bacilli.
• All layer of skin and subcutaneous tissue are acutely
inflammed and infiltrated with polymorphonuclear leukocyte
![Page 33: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/33.jpg)
![Page 34: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/34.jpg)
CELLULITIS
Culture purulent material from the lesion.
Inject 0.5 ml of NSS into the erythematous margin and
aspirate the content for culture. ( recommend in severe case )
Early simple case : Treated with parenteral penicillin G.
Severe case or immunocompromised host : add
aminoglycoside or agent that cover Gm negative pathogen.
• Management
![Page 35: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/35.jpg)
CELLULITIS Antibiotic : Penicillin G ( Strept. )
Cloxacillin ( Strept + Staph )
Alternative : First gen ceph , Vancomycin , Clindamicin.
Immunocompromised host : should add aminoglycoside
Local care : No incision and drain.
Immobilization , elevation , warm compression.
• Management
![Page 36: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/36.jpg)
![Page 37: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/37.jpg)
SUBCUTANEOUS ABSCESS
Etiology S. aureus : upper part of body Anaerobe : mixed organism perineum , inguinal , buttock Enteric gm negative + anaerobe : nonperineal area Proteus mirabilis , E.Coli. Sterile abscess : very few ( except : previous antibiotic ,
inappropriate collection of specimen , foreign body )
![Page 38: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/38.jpg)
SUBCUTANEOUS ABSCESS • Clinical manifestation Induration , Fluctuation
Pain and swelling around the infected site.
Cellulitis , lymphedema , lymphangitis and regional lymphadenopathy
Less systemic symptom , low grade fever
Needle aspiration may be useful in questionable case
![Page 39: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/39.jpg)
![Page 40: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/40.jpg)
![Page 41: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/41.jpg)
![Page 42: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/42.jpg)
![Page 43: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/43.jpg)
SUBCUTANEOUS ABSCESS
Parenteral antibiotic :
1. Sepsis : high fever , tachycardia
2. Abscess in critical area : Mastoid area , central triangle of face ( drain to carvernous sinus )
3. Risk from systemic disease : rheumatic heart . Hodgkin disease , severe diabetes
4. Immunocompromised host.
• Antibiotic • Treatment
![Page 44: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/44.jpg)
NECROTIZING FASCIITIS • Definition
Infection of subcutaneous tissue , which spread in the fascial clefts overlying deep fascia and sparing the skin. Skin gangrene result only after the vessels to the skin thrombose.
• Etiology
Streptococcus , staph.
Most often : a synergistic bacterial infection : polymicrobial ( aerobe + anaerobe )
![Page 45: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/45.jpg)
NECROTIZING FASCIITIS
• Presentation
Portal of entry is obvious : Trauma , postoperative wound
infection , perianal abscess , etc
Early : Large area of pain , swollen , erythema , fever.
If left untreated : necrosis of skin , paresthesia ,
subcutaneous crepitation , bleb at the skin , hypotension jaundice.
![Page 46: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/46.jpg)
![Page 47: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/47.jpg)
![Page 48: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/48.jpg)
![Page 49: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/49.jpg)
• In questionable case : Probing instrument through the area of necrosis or small incision between subcutaneous tissue and deep fascia.
![Page 50: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/50.jpg)
NECROTIZING FASCIITIS
1. Supportive symptomatic
Fluid resuscitation , adequate oxygenation , correct acidosis , pain control.
2. Adequate antibiotic
Depend on Gm stain.
Empirical treatment : Penicillin G + aminoglycoside + Clindamycin.
• Treatment
![Page 51: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/51.jpg)
NECROTIZING FASCIITIS 3. Definitive surgery
Most important.
Debridement : incision should extend to expose normal
fascia , preserve viable skin flap , Packed loosely with moist
gauze.
Repeat exam the wound daily.
Redebride the wound if neccesary.
Closure the defect by Skin graft if infection subside.
![Page 52: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/52.jpg)
![Page 53: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/53.jpg)
![Page 54: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/54.jpg)
![Page 55: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/55.jpg)
![Page 56: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/56.jpg)
Cellulitis VS Necrotizing fasciitis
Cellulitis Necrotizing fasciitis
Initiating picture Generalized malaise , fever ,
weakness
More seriously ( may be sepsis )
Wound
assessment
Wound edema , skin : red ,
warm , Vesicle may be
present in untreated patient
Early : wound edema , associated
with thin serum from lesion
Late : Large area of edema ,
necrosis of skin , crepitation may
occur
Patient’s comfort Tenderess around , pruritus
common Extreme pain often out of
proprtion to wound.
Resolution Significant resolution of sign
and symptom within 24–48hrs.
of antibiotic treatment
Little or no resolution of sign
and symptom after antibiotic
treatment
![Page 57: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/57.jpg)
FOURNIER’S IDIOPATHIC GANGRENE
• Infection of subcutaneous tissue of perineum cause
gangrene of the skin and subcutaneous tissue.
• Streptococcus pyogenes , S. aureus , with Facultative
enteric organism ( E.coli , Klebsiella , Enterococci ).
May have synergistic anaerobic bacteria
(Bacteroides , Peptostreptococcus .
![Page 58: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/58.jpg)
![Page 59: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/59.jpg)
FOURNIER’S IDIOPATHIC GANGRENE
• Treatment
Broad spectrum antibiotic ( IV form ) same as
necrotizing fasciitis
Debridement the necrotic skin , carefully
preserve blood supply to testis.
If infection subside : closure by suture or skin
graft.
![Page 60: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/60.jpg)
![Page 61: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/61.jpg)
![Page 62: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/62.jpg)
MYONECROSIS
• Infection of muscle caused necrosis of muscle
• Devided into 2 group
1. Clostridial myonecrosis
2. Nonclostridial myonecrosis
![Page 63: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/63.jpg)
MYONECROSIS
• Etiology
80-90% C. Perfringen , 10% C. Septicum
5% C.Bifermentans , C. Histolyticum and C.
Phallax.
• Clostridial myonecrosis
![Page 64: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/64.jpg)
MYONECROSIS
• Presentation
Incubation period : 6 hours - 3 days.
Abrupt onset , severe pain ( like arterial occlusion )
Edema , cold skin , tenderness on pressure , Muscle edema
herniate through wound , serosanguineous discharge , Gas
bubble , crepitation , Bleb may occur at the skin.
Severe systemic toxicity , Shock , renal failure , sepsis.
• Clostridial myonecrosis
![Page 65: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/65.jpg)
![Page 66: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/66.jpg)
![Page 67: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/67.jpg)
MYONECROSIS
• Diagnosis
Clinical finding
Radiologic exam : Plain film , CT , MRI
air in soft tissue
Serum creatine phosphokinase ( CPK ) level
Operative exploration in questionable case. : smell , color ,
bleeding , contractility of muscle
• Clostridial myonecrosis
![Page 68: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/68.jpg)
MYONECROSIS
• Treatment
General support
Antibiotic : Penicillin G high dose
Alternative : metronidazole ,
aminoglycoside + Clindamycin.
• Clostridial myonecrosis
![Page 69: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/69.jpg)
MYONECROSIS
Emergency surgery : Debridement of all necrotic tissue , Noncontracted
muscle Fasciotomy : reduce pressure in fascial compartment
Amputation : Indication 1. Massive gangrene of muscle , unstable vital sign 2. Compound fracture with gas gangrene 3. Main vascular injury with gas gangrene
• Clostridial myonecrosis
![Page 70: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/70.jpg)
Hyperbaric oxygen therapy ( HBO ) • Administration of 100% oxygen at greater than
atmospheric pressure to produce arterial hyperoxia
• May be benefit in necrotizing soft tissue infection
• Diminished tissue loss , decrease mortality rate.
• Should be used as adjunctive with debridement and antibiotic
• Complication : Barotrauma , tympanic membrane rupture , pneumothorax , air embolism , oxygen toxicity
![Page 71: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/71.jpg)
• Monoplace chamber
![Page 72: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/72.jpg)
• Multiplace chamber
![Page 73: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/73.jpg)
Clostridial myonecrosis Nonclostridial myonecrosis
Onset Acute ( may be in 6 hr to 3 days
following injury )
Over several days
Pain Severe and appears early May be severe later in illness
Tissue gas Present Rare
Odor of exudate Slightly foul or
Peculiar sweet
Variable : may be foul
Cutaneous
changes
Bronze discoloration,
Edema , bullae and necrosis
Erythema
Systemic toxicity Extreme and evident early Present only late
Progression Extremely rapid Slow
Gm stain Gram positive rods
and few neutrophiles Gram positive cocci in chain and
numerous nutrophiles
![Page 74: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/74.jpg)
Clostridium tetani, ( gram-positive spore-forming bacillus ).
Breaks in the mucosal or skin barriers. Tetanospasmin : Anterior horn cells of spinal cord & brainstem. Blocks inhibitor synapses, leading to muscle spasms
and hyperreflexia. Tetanolysin : Cardiotoxic , hemolysis Not major clinical importance.
TETANUS
![Page 75: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/75.jpg)
![Page 76: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/76.jpg)
The median incubation : 7 to 8 days.
Generalized tetanus
Initial symptoms are variable.
Restlessness and headache.
Muscle spasms ,discomfort in neck, lumbar & jaws.
Swallowing difficult.
Stiff neck.
Orthotonos.
TETANUS
![Page 77: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/77.jpg)
Generalized toxic convulsions are frequent,
exhausting, and unpredictable.
Any slight external stimulus ( a breeze, sudden
movement, noise, or light ) and internal stimuli (cough,
swallow, distended bladder) may trigger generalized
convulsions.
TETANUS
![Page 78: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/78.jpg)
Treatment
Tetanus immunoglobulin (TIG) 500 to 10,000 units.
Intensive care unit. Quiet rooms.
Sedation, muscle relaxants. Adequate doses of analgesics.
Adequate nutrition, Laxatives, Urinary catheter, Eye protection.
Debridement of wound.
Penicillin G
TETANUS
![Page 79: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/79.jpg)
Prevention
TETANUS
![Page 80: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/80.jpg)
BODY CAVITY INFECTION
![Page 81: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/81.jpg)
BODY CAVITY INFECTION
• Primary peritonitis
Caused : single organism
Most common : young children and adults with
ascites or renal failure
Treated with antibiotics.
Peritonitis and Intraabdominal Abscess
![Page 82: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/82.jpg)
• Secondary bacterial peritonitis Result of a defect in GI tract , requires operative
intervention.
Treatment : surgery ( control the source of contamination, remove bacteria and adjuvant materials from the peritoneal cavity).
Antibiotic therapy
Peritonitis and Intraabdominal Abscess
BODY CAVITY INFECTION
![Page 83: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/83.jpg)
• Tertiary peritonitis
Peritonitis-like syndrome result of a disturbance in
the host's immune response
Characterized by peritonitis without evidence of
pathogens or peritonitis caused by fungi or low-grade
pathogenic bacteria.
Peritonitis and Intraabdominal Abscess
BODY CAVITY INFECTION
![Page 84: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/84.jpg)
PROSTHETIC DEVICE-ASSOCIATED
INFECTIONS
![Page 85: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/85.jpg)
PROSTHETIC DEVICE-ASSOCIATED INFECTIONS
• Cardiac valves, pacemakers, vascular grafts, and artificial joints.
• Associated with great morbidity.
• Complete removal of all foreign material and antibiotic therapy.
• Vascular grafts : may be salvaged by debridement, povidone-
iodine–soaked dressings, and antibiotic therapy when the suture
line has not been infected.
• Infected prosthetic joints and pacemakers : may be salvaged by
antibiotic irrigation of the joint or pacemaker.
![Page 86: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/86.jpg)
![Page 87: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/87.jpg)
HOSPITAL-ACQUIRED (Nosocomial)
INFECTIONS
![Page 88: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/88.jpg)
• Hospital-acquired infections are infections that develop
within a hospital or are acquired within a hospital.
• On surgical services urinary tract infections are most
common, followed by wound infection, lower respiratory
infection, bacteremia, and cutaneous infection.
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 89: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/89.jpg)
Classification of Operative Wounds
Clean
Elective, primarily closed, and undrained
Nontraumatic, uninfected
No inflammation encountered
No break in asepsis
Respiratory, alimentary, genitourinary, or oropharyngeal tracts not entered.
Wound Infections HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 90: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/90.jpg)
Clean-contaminated Alimentary, respiratory, or genitourinary tracts entered
under controlled conditions without unusual contamination Appendectomy Oropharynx entered Vagina entered GU tract entered in absence of culture-positive urine. Biliary tract entered in absence of infected bile. Minor break in technique. Mechanical drainage.
Wound Infections HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 91: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/91.jpg)
Contaminated
Open, fresh traumatic wounds.
Gross spillage from gastrointestinal tract. Entrance of GU or biliary tracts in presence of infected
urine or bile. Major break in technique Incisions in which acute nonpurulent inflammation is
present
Wound Infections HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 92: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/92.jpg)
Dirty and Infected
Traumatic wound with retained devitalized tissue, foreign
bodies, fecal contamination, or delayed treatment, or from a
dirty source
Perforated viscus encountered
Acute bacterial inflammation with pus encountered during
operation
Wound Infections HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 93: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/93.jpg)
• Wound infection rates in large series are
1.5 to 3.9 percent for clean wounds.
3.0 to 4.0 percent for clean-contaminated wounds.
8.5 percent for contaminated wounds.
28 to 40 percent for dirty wounds
Wound Infections HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 94: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/94.jpg)
An incisional ( superficial ) wound infection : within 30 days after operation involves skin or subcutaneous tissue above the
fascial layer and : (1) Purulent drainage
(2) An organism (3) The wound is opened deliberately by the surgeon, unless
the wound is culture-negative.
Wound Infections Definition
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 95: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/95.jpg)
![Page 96: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/96.jpg)
Deep surgical wound infection :
within 30 days (no prosthesis) and within 1 year (implant)
Infection involves beneath the fascial layer and : (1) Spontaneously dehiscens or opened by surgeon when the patient has a fever ( >38 °C)
(2) An abscess , evidence of infection directly under the incision. (3) The surgeon diagnoses infection.
Wound Infections Definition
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 97: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/97.jpg)
![Page 98: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/98.jpg)
Wound Infections
• Operating Room Environment Air-handling systems Filtration of air. Operating room air should have a positive pressure relative to air
in the corridors. Special laminar flow systems with high efficiency particulate air
(HEPA).
Reducing the number of people Limiting talking
Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 99: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/99.jpg)
![Page 100: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/100.jpg)
• Instruments and Drapes
Properly sterilized instruments
Wet drapes
Adhesive plastic drapes do not lower the incidence of
wound infection.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 101: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/101.jpg)
![Page 102: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/102.jpg)
MOIST HEAT
![Page 103: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/103.jpg)
Drape
![Page 104: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/104.jpg)
• Hand Washing
Removes dirt and desquamated skin and reduces the number
of microbes on the skin.
Tradition : scrubbing for 10 min, 2 brushes.
Washing 5 min, 1 brush : equal reduction in skin bacterial
counts.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 105: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/105.jpg)
Hand washing
![Page 106: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/106.jpg)
Hand washing
![Page 107: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/107.jpg)
• Gloves
30 % of gloves have defects by the end of the operation.
The CDC : wearing two pairs of gloves to reduce the
likelihood of exposure to patient's blood.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 108: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/108.jpg)
• Other Barriers
Caps : prevent hair and skin scales (and adherent bacteria).
Masks : prevent droplets produced during speaking or
coughing.
Gowns : prevent desquamated skin and other particles.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 109: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/109.jpg)
Operative
clothes ,
cap , mask and
footwear
![Page 110: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/110.jpg)
GOWN
![Page 111: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/111.jpg)
• Preoperative Stay
Longer preoperative hospitalizations : more likely to
develop postoperative wound infections.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 112: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/112.jpg)
• Preoperative Shower
A shower with an antiseptic soap can reduce the resident
skin bacteria.
No reduction in wound infection rates in patients who had a
preoperative shower.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 113: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/113.jpg)
• Remote Infections
Remote infections can tripple the rate of wound infection.
Elective operations should be delayed until the dermatitis
is treated, especially if the skin incision is near or through
such regions.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 114: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/114.jpg)
Herpes
![Page 115: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/115.jpg)
• Hair Removal
Nicks and cuts caused by shaving are sites where bacteria can
proliferate. When shaving is done the night before operation, the wound infection rate is higher than when shaving is done in the operating room immediately before operation.
Clipping with an electric clipper is better.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 116: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/116.jpg)
• Skin Preparation
5-min scrub with povidone-iodine followed by
painting with povidone-iodine solution.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 117: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/117.jpg)
• Improving Host Defenses Malnutrition
Obesity
Cirrhosis.
Uremia
Diabetes
Smoking
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 118: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/118.jpg)
• Prophylactic Antibiotics
Clean operations : Staph. aureus, Staph epidermidis, and
gram-negative enteric bacteria
Gram-negative enteric bacteria : Gastroduodenal and
biliary tract procedures, colorectal surgery, appendectomy, and
gynecologic surgery.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 119: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/119.jpg)
Antibiotics should generally be given intravenously 30 to 60
minutes before operation.
Antibiotic dose should be repeated if
1. The operation lasts longer than 4 h
2. Twice the half life of the antibiotic
3. Blood loss has been great.
Should not be continued beyond the day of operation.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 120: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/120.jpg)
• Indications for prophylactic antibiotic
1. Bacterial contamination of the wound is likely
2. Clean operations with prosthetic device.
3. Traumatic wounds.
4. Intestinal tract has been entered.
5. Elective operations on the intestine or colon.
6. Gastroduodenal operations with increased gastric flora.
7. High-risk biliary tract operations.
8. Gynecologic operations.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 121: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/121.jpg)
The bacteria in the stomach are increased in
1. Gastric outlet obstruction,
2. Decreased gastric acidity (achlorhydria, antacid or H2-
receptor blocker therapy, gastric cancer)
3. Normal or high acidity if bleeding has occurred.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS
![Page 122: Kirati Watcharachan MD. Department of Surgery Faculty of ... · Surgical infections : infections that require operative treatment or result from operative treatment. • Infections](https://reader034.fdocuments.us/reader034/viewer/2022042409/5f26b70702ea740adc5092be/html5/thumbnails/122.jpg)
High-risk biliary tract operations
1. Jaundice, bile duct obstruction, stones in CBD.
2. Reoperative biliary tract operation.
3. Acute cholecystitis.
4. Age greater than 70 years.
Wound Infections Prophylaxis
HOSPITAL-ACQUIRED (Nosocomial) INFECTIONS