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Kim WitmerSenior Vice PresidentChief Financial Officer
Michael Nunn, Ph.D.Executive Director
Research Development
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EndocrinologyDevelopmental BiologyNeurobiologyMetabolism
Plant BiologyCognitive Neuroscience
Chemical BiologyBiophotonics
Molecular Biology Cancer Aging Immunology
Gene Therapy Stem Cells
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Founded by Jonas Salk in 1970Designated as NCI Basic Center in
1973• Center includes 30 Faculty members• 200 Post-doctoral researchers• 50 Graduate research students
Cancer Center Director: Tony Hunter, Ph.D.
Cancer Center is distributed across Salk• 62% of Institute investigators participate in
Center programs
Salk Institute Cancer Center
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Institutional:• Philanthropy• Revenue Diversification• Cost Savings & Efficiencies
Research Development:• Strategies• Innovation Grant Program • Advocacy
Responding to the Fiscal Environment-2014
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Operating Revenue by Source
Federal43%
State4%
Founda-tions &
Contribu-tions30%
Corpo-rate5%
HHMI10%
Investment & Other8%
FY13 $109M
Federal61%
State0.5%
Founda-tions &
Contribu-tions
17.0%
Corpo-rate1.5%
HHMI10%
Investment & Other10.0%
FY03 $85M
Note: Excludes subcontracts going out
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Increased direct support to Investigators• Increased bridge funding• Raised funds for 21 chairs for Cancer
Center Investigators• Provided Developmental chairs for 5 new
Cancer Center members• Found major donors to build new Core
Resources Biophotonics, Next Gen Sequencing and
Bioinformatics
• Target Cancer Center research in Capital Campaign
Philanthropy
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Encourage Investigators to pursue all grant application options
Secured large foundation grant for multiple PI’s & Cores
Developed inter-institutional shared resources
Hired Director of Research Development
Revenue Diversification
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Major Administrative Costs Savings
Restructure Mailroom & Telecomm
Central Plant Upgrade – requires less maintenance
ARD – restructuring for efficiency
Procurement – savings
Worker’s Compensation Improvements
Renegotiation of Large Contracts
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NIH applications, Awards and Success Rates
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The Research Development Office
The office provides –
1. Stewardship and Coaching: Individual R01s Managing Change
2. Launching New Projects: Centers and Programs
3. Seed Funding
4. Advise Senior Leadership
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Strategies for Success
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1. The Right Opportunity
2. The Right Audience
3. Developing Agency Support
Themes:
Strategies for Success
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Agency Websites: NIH Guide
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Award Search: NIH RePORTER
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The Right Opportunity
Challenges for Cancer Research: Success Rates
2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 20120.0%
5.0%
10.0%
15.0%
20.0%
25.0%
30.0%
35.0%
NCINHLBINIDDKNIAIDNINDSNIGMSNEI
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The Right Opportunity
Agency websites – become a pro:funding opportunities✪ NIH http://grants.nih.gov/grants/oer.htm✪ NSF http://nsf.gov/funding/✪ CDMRP http://cdmrp.army.mil/funding/prgdefault.shtml✪ Grants.govfunded projects✪ NIH http://projectreporter.nih.gov/reporter.cfm✪ NSF http://nsf.gov/awardsearch/✪ CDMRP http://cdmrp.army.mil/search.aspx
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Automated Funding Announcements:Agency or Commercial
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The Right Audience
Who will review your grant?
This is ESSENTIAL information to have
BEFORE you start writing …
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Click on the grant number
NIH RePORTER:
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StudySection
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• http://public.csr.nih.gov/StudySections/Pages/default.aspx
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Program Official
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Developing Agency Support
• The best time to contact a Program Director?– BEFORE YOU START
– required 6 weeks before submission of grants >$500K– NIDDK asks for 3-6 months notice for large programs
Other Topics:• Summary Statements• Etiquette• Negotiating an Award
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The Research Development OfficeLeadership: Push vs. Pull
Challenge for developing new projects and building teams • Pull:
– Investigator has a project and/or team already developed
• Push:– Outsider [President?, Chair?, Executive Director?]
identifies collaborative research
opportunities in line with faculty
research interests
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The Research Development Office
The Push – Match opportunities to PIs:
• Find Leaders • Collaborators
– Identify experts (preferably local) to build a team
Sell the project:• Know the competition
– Identify similar funding• Timing of Submission… use NIH RePORTER
P30 Program and External Advisory Board Meetings
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The Research Development Office
Sample RDEV projects at the Salk Institute:
NCI Cancer Center Renewals in 2008 and 2013
Sanford Consortium: $43M facility award from CIRM
New Centers, complementing the CCSG
NINDS and NEI P30 awards …
CIRM Center of Excellence in Genomic Medicine
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Seed Funding
Salk Innovation Grant Program
•Established in 2006 with donor funding
•Average expenditures $1 million/year
•Awards up to $100K direct costs for one year
•Internal peer review with option for outside critiques
•2 rounds/yr, @ 12 applications, 4 awards
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Salk Innovation Grants: Leverage
2007 (9 awards)
2008 (11 awards)
2009 (9 awards)
2010 (7 awards)
2011 (7 awards)
$0
$2
$4
$6
$8
$10
$12
$ 0.9M $1.2M $0.97M $0.85M $0.85M
$3.7 M
$11 M
$7.3 M
$30K
Awarded LeverageIn
Mill
ions
Major new projects seeded by SIG funding:• $5 M Industry partnership program• $2 M ARRA Grand Opportunities Award• $4 M Foundation Award • $4 M for two new NIH R01s
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Seed Funding
Cancer Center Pilot Grants
• Initiated in 2009
• Uses NCI CCSG Developmental Funds
• Supports Cancer Focus:– Collaborations
both intra- and inter-programmatic– Translational Research
external, orusing C3 resources (current RFA)
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Advocacy – Affecting Change
Administrators can serve as liaison to leaders at Federal and State Agencies – NIH, CIRM, etc.
Administrators can join advocacy and lobbying groups– Association of Independent Research Institutes
(AIRI)
Example: Special Council Review of Well-Funded Investigators
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H-index Analysis: Investigators from 4 Cancer Centers at AIRI Institutions
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1 2 3 4 5 6 7 8 9 10 11 120
1000
2000
3000
4000
5000
6000
7000
8000
NewRenewalTotal
Analysis of NIH Competing Awards, 2002-2013
1 2 3 4 5 6 7 8 9 10 11 121.40
1.50
1.60
1.70
1.80
1.90
2.00
2.10
2.20
2.30
2.40
ratio type 1/2
ratio type 1/2
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Management■Human Resources■Infrastructure
Development Portfolio Diversification
Unrestricted funds Foundation & corporations
Grant Development Seed Funding
Advocacy
Summary
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What is your state doing to support Cancer Research?
What management strategies have helped you conserve resources?
Are there alternative approaches to funding start-up projects?
Who you gonna call to change Federal or State policy?
Questions