Kidney Disease newspaper - MISS...
Transcript of Kidney Disease newspaper - MISS...
Trojan Science Today
Vol I. No. 2 Copyright © 2016 Torjan Science Today Winnipeg, MB, December 20, 2016 Vincent Massey Free
Kidney Disease Research Grade11BiologyClassLearnsAboutKidneyDiseases
ExcretionandWasteManagementUnit
Miss.PaslawskiWinnipeg,MB
OverthepastfewweekswehavebeenlearningaboutexcretionandwastemanagementinBiology30S.Duringthistimewehavedonesomehandsonactivitiesthatincludedakidneydissectionandcreatingmodelnephrons.Welearnedabouturinalysisbyresearchingtheprocess,necessarychemicals,andapplicationsofdiabetes,pregnancyanddrugstonameafew.NowthatweareattheendoftheunitweconcludedwithresearchintoKidneyDiseases.Eachstudentwasresponsibleforacontributiontothisnewspapertocreateatoolforlearningaboutotherdiseases.
Kidney Failure
OliviaWinnipeg,MB
KidneyFailureiswhenthekidneysnolongerareabletoproperlyfilterthemetabolicwastesfromtheblood.Somesymptomsthatcouldhelpdiagnosekidneyfailureareconfusion,nausea,reducedamountofurine,seizuresandswellingtoyourlegs,anklesandfeet.Whentreatingkidneyfailuretherearemultipledifferentoptionsdependingonthecauseofyourkidneyfailure.Twocommonoptionsaredialysiswhichusesamachinetofilterouttheblood,orakidneytransplant.Whengettingakidneytransplanttherenormallyisalongwaitinordertofindthebestpossiblematchforyourbody.Whenyoureceiveakidneytransplantdialysisisnolongerneeded.Thedownsidetogettingatransplantisthatyoumusttakedrugsaftersurgerythatwillpreventimmunesystemactivityandhasotherserioussideeffectsbutitwillreducetheriskofkidneyrejection.Afterallthisthereisachancethattheysurgeryitselfcouldkillyou.Somecommonandeasywaystopreventkidneyfailurearefollowingtheproperdosageofoverthecountermedication,listentoyourdoctor’sdirectionsifyou’reexperiencingkidneyorurinarytractissuesandlimityourexposuretochemicalssuchashouseholdcleaningproducts,tobaccoandothertoxicsubstances.
Acute Tubular Necrosis
AngelaWinnipeg,MB
AnAcutetubularnecrosisiskidneydisorderwhenthereisdamageinthetubularcellsofthekidneys.Tubularcellssalts,excessfluid,andalsowasteproductsformtheblood.Whenthesetubularcellsaredamagedtheycouldalsoleadtoyouhavinganacutekidneyfailure.SomethingthatcancauseATNisthelackofoxygenthatisreachingthecellsofthekidney.
• Problemswakingup• Feelingdrowsythroughouttheday• Decreasedurineoutputornourineatall
Firstthingadoctormightdototreattheacutetubularnecrosisisgiveyoumedicationsthatwillallowyourkidneystodecreasethefluidandwastebuildupinthem.Yourdoctormighttellyoutocontrolyourwaterintakebecauseifyouwillhavetoomuchwateritcanleadtoswelling.Theswellingcouldhappeninyourarms,legsandyourfeet.Yourdoctorcouldevendoadialysiswhichwillremoveexcessfluidtemporarilyandwastealso.Thereforyoursymptomswon’tbesobad.Thisisaverygoodoptiontodoifyourpotassiumisveryhigh.
Prevention:• Managediabetes,heartproblemsandliverdisorderstoreducetherisk• Monitorbloodiftakinganymedicationsthatcanbeharmfultoyourkidneys• Treatconditionsthatwilldecreasebloodflowordecreaseoxygentothekidneys
Renal Tubular Acidosis KobiWinnipeg,MB
RenalTubularAcidosis(RTA)isamedicalconditionthatinvolvesanaccumulationofacidinthebodyduetoafailureofkidneystoappropriatelyaciditytheurine.SymptomsofRTAare:
• Kidneystones• Muscleweakness• Fatigue• Increasedbreathingrate• Confusionordecreasedalertness
Thegoalistorestorenormalacidlevelandelectrolytebalanceinthebody.Thiswillhelpcorrectbonedisordersandreducebuildupinthekidneys(nephrocalcinosis)andkidneystones.Theunderlyingcauseofrenaltubularacidosis(RTA)shouldbecorrectedifitcanbeidentified.Medicinesthatmaybeprescribedincludepotassiumcitrateandsodiumbicarbonate.Thesearealkalinemedicinesthathelpcorrecttheacidicconditionofthebody.Sodiumbicarbonatemaycorrectthelossofpotassiumandcalcium.Thereisnopreventionforthedisorder.
Chronickidneydisease,alsocalledchronickidneyfailure,itwilldescribethegraduallossofyourkidneyfunction.Yourkidneysfilterwastesandexcessfluidsfromyourblood,whicharethenexcretedinyoururine.SomesymptomsyoucangetfromchronickidneydiseaseisWeightloss,alsocouldpeeoutbloodandveryitchyskinKidneytransplantisawaytotreatabadkidney.Drinkalcoholinmoderation,ifatall.Ifyouchoosetodrinkalcohol,dosoinmoderation,maintainahealthyweight,anddon’tsmoke.Alsomanageyourmedicalconditionswithyourdoctor'shelporsomeonewhoknowswhatthey’redoing.
Kidney Disease NoahWinnipeg,MB
Renal Tubular Acidosis (RTA)
AnthonyWinnipeg,MB
Renaltubularacidosis(RTA)isadiseasethatoccurswhenthekidneysfailtoexcreteacidsintotheurine,whichcausesaperson’sbloodtoremaintooacidic.Threesymptomsthatcouldbeusedtodiagnoserenaltubularacidosis(RTA),Acid-basebalanceinthebloodandurinesamples.Additionalinformationaboutthesodium,potassium,andchloridelevelsinurinealsoPotassiumlevelinthebloodwillhelp.Type1RTAcanbetreatedwithalkalisupplement,around1-2kg/day.WhileType2RTAcanbetreatedthesame,around10-15kg/dayofalkaliistypicallyrequiredtostayaheadofurinaryexcretion.Manyaskifthisdisease/conditioncanbeprevented,unfortunatelyitcannot.
Kidney Stones
MarissaWinnipeg,MB
Kidneystonesaresmallcrystal-likeobjectsthatformwhensubstancesintheurineclumptogether.Thesecanformeitherfromtoomanyofthecrystalformingsubstance,orlackofsubstancesthatpreventcrystalsfromstickingtogether.Themajorityofstonesarecalciumstones,theymayalsobestruvitestones,uricacidstones,cysteineorothermoreraretypes.Somesymptomsofkidneystonesarepaininthelowerabdomenandgroin,sideandbackorwhenurinating.Urinemaybepink,redorbrown,cloudyorfoul-smellingandthesubjectmayfeeltheneedtourinatemoreoftenthanusual.Ifthepersonsuspectsakidneystonetheywillhavetogoinforbloodtesting,urinalysisandimaging.Oncediagnosed,thereisnotmuchtreatmenttobedone.Drinkinglotsofwaterwillhelppassthestoneandpainrelieverscanhelpsubsidepain.Ifthestoneislargeenough,surgerymaybeneededtoremoveit,butthisisonlyinrarecases.Thenationalkidneyfoundationnamesafeweasywaystopreventkidneystones.
1. Stayhydrated.Ifyouaresweatingalotespecially.2. Don’tavoidcalcium.Somebelieveavoidingcalciumwillreduce
calciumstones,butitinfactincreasestherisk.3. It’snotjustoneanddone.Ifyou’vehadonebefore,besuretofollow
thedietsadmedicationsgivenafteroritwillreoccur.4. Donoteatlargeamountsofredmeats,organmeatsorshellfishas
theycausehighlevelsofuricacid.
Nephrocalcinosis
AshleyWinnipeg,MB
Nephrocalcinosisisadisorderwherethereistoomuchcalcium(mainlyintheformsofcalcium-phosphateandcalcium-oxalate)depositedinthekidneysspecificallyintheparenchymaandtubules.Itiscommoninprematurebabies.Therearethreetypesofnephrocalcinosis;Chemical,Medullary,andCortical.Therearen’tmanyearlysignsofnephrocalcinosisbutafewsymptomsareincreasedurinationandthirst,bloodintheurine,andhypertensionwhichishighbloodpressure.Themainfocusofthetreatmentistoreducethesymptomsandpreventmorecalciumfromcollectinginthekidneys.Treatmentwillworktolessentheabnormallevelsofcalcium,phosphate,andoxalateintheurineandblood.Youmaybeputonmedicationlikemicrozidethatcausescalciumlossorbeaskedtomakechangesinyourdiet.Topreventnephrocalcinosisitisbesttopromptlytreatdisordersthatleadtoit,includingrenaltubularacidosis.
Glomerulonephritis(GN)iswhenyourglomeruli,structuresmadeupoftinybloodvesselslocatedinyourkidneys,areinflamed.Glomerulihelpfilteryourbloodandremoveexcessfluidsinyourbody.Theyareveryimportantandiftheybecomedamagedyourkidneyswillstopworkingproperly.Therearetwotypesofthisdisease,acute(sudden)glomerulonephritisandchronic(longterm)glomerulonephritis.SymptomsofAcuteGNincludepuffinessintheface,noturinatingasoftenasnormal,findingbloodinyoururine,fluidbuild-upinyourlungswhichcancausecoughing,andhighbloodpressure.ChronicGNcanappearwithoutanysymptomsoraslowdevelopmentofsymptoms.Somesymptomsthatmightoccurincludesfindingbloodorexcessproteininyoururine,highbloodpressure,swellinginanklesandface,frequentlyhavingtopeeatnight,bubblyorfoamyurine,abdominalpainorfrequentnosebleeds.Todiagnoseglomerulonephritisyouwillneedtogetaurinalysisdoneandbloodtestsormoreadvancedtestingmaybeneededaswell.Glomerulonephritisrequiresimmediatetreatment.DependingonthetypeofGNyouaresufferingfromandthecauseofit,thetreatmentmayvary.Onetreatmentoptionistocontrolhighbloodpressurebyusingprescribedbloodpressuremedicationssuchascaptopril,lisinopril,andperindopril.Yourdoctormayalsoprescribeyouangiotensinreceptorblockerslikelosartan,irbesartan,orvalsartan.Ifyourimmunesystemisattackingyourkidneysyoumayhavetousecorticosteroidstoreducetheimmuneresponse.SpecificallyforchronicGNyouwillneedtoreducetheamountofprotein,salt,andpotassiuminyourdietaswellaswatchhowmuchliquidyoudrinkinaday.Thereisn’treallyawaytoreducetheriskofgettingglomerulonephritisbuttherearesomeprecautionsyoucantake.Theseprecautionsincludegettingtreatmentforstrepthroatimmediately,preventinginfections,followingsafesexguidelines,avoidingdruguse,controllingyourbloodpressureandcontrollingyourbloodstructure.
Glomerulonephritis
KennedyWinnipeg,MB
Horseshoe Kidney
CassidyWinnipeg,MB Ahorseshoekidneyisaconditionwherethetwokidneysconnectduringfetaldevelopment.Thebaseofthekidneysbecomefusedtogetherastheyrisefromthepelvicareaintotheirnormalposition.Abandoftissuecalledtheisthmusattachesthetwofunctioningkidneystogether.Ahorseshoekidneyisveryhardtodetect.Onlytwo-thirdsofchildrenwillshowsymptoms,andlotsgoundetected.Forpatientswhodohavesymptoms,theyarediagnosedastheresultofaninfectionorkidneystone.Anothersymptomishydronephrosis,whichiswhenthereisanobstructioninthekidneys.Treatmentforahorseshoekidneyisnotnecessaryunlessyourchildisexperiencingsymptoms.Andiftheyareexperiencingsymptoms,yourchildwillneedtotakeantibioticsorevengetasurgery.Thereissadlynowaytopreventahorseshoekidneyfromforming,asitisformedasthefetusdevelops.
Glomerulonephritis
DanielleWinnipeg,MB
Glomerulonephritisisinflammationoftinyfiltersinyourkidneys.AlsocalledGlomerularDisease,Glomerulonephritiscanbeacuteorchronic.Thisdiseasecanbelifethreateningandwillneedimmediateattention.Symptoms
• Pinkorcola-coloredurinefromredbloodcellsinyoururine• Foamyurinecausedbyexcessprotein• Highbloodpressure
Treatmentoptionswilldependonifyouhaveanacuteorchronicformofthisdisease,theunderlyingcause,andtheseverityofyoursymptoms.Onetreatmentwouldbetocontrolyourbloodpressure,inwhichyouwouldbeprescribedtobloodpressuremedication.Theremaybenowaytopreventmostformsofthisdisease,buttherearestepsyoucantaketoreducethechanceofit.
• Getgoodtreatmentsforstrepinfection,sorethroats,andimpetigo• Followsafesexguidelinesandavoiddruguse• Controlyourbloodpressure• Controlyourbloodsugar
Horseshoe Kidney
NicolinaWinnipeg,MB
HorseshoeKidneyisaconditionwhereyourtwokidneysjointogetherattheirendstoformasingleorgan.Thishappensduringfetaldevelopmentaffecting1/500kidsandismorecommoninmalesthanfemales.Ifyouhavethiscondition,youaremorelikelytodevelopkidneystones,UTI’s(urinarytractinfections)followedbyhighfever,increasedprobabilityofcanceroustumorsinthekidneyandhydronephrosis(waterinthekidney).Thereisnotreatmentorcureforhorseshoekidneyandinmostcases,ifyoudonotexperiencesymptomsorsideeffectsthenitisunnecessarytoseekacure.Incaseswithseveresymptomssuchasblockageofurineorurineflowingbackwardsfromthebladder(“vesicoureteralreflux”),thenthesecanreceiveseparatetreatment.
Kidney Failure AndrewWinnipeg,MB
Abuild-upofwasteproductsandexcessfluidinthebodythatmaycauseweakness,shortnessofbreath,lethargy,swelling,andconfusion.Inabilitytoremovepotassiumfromthebloodstreammayleadtoabnormalheartrhythmsandsuddendeath.Initiallykidneydiseasemaycausenosymptoms.IfyouhaveHBPToavoidkidneydiseasekeeptrackoflipidintakeandbloodpressure.Smokingcanalsobeabigfactor.Thegoaloftreatmentforchronickidneydiseaseistopreventorslowfurtherdamagetoyourkidneys.Anotherconditionsuchasdiabetesorhighbloodpressureusuallycauseskidneydisease.
Chronickidneydiseaseisaslowdeteriorationofyourkidneyfunctions.Whenthedeteriorationisasatextremelevelthefiltrationsysteminyourkidneysstopsworkinglettingfluidsthatneedtobeexcretedbuildupinsidekidneys.Therearevarioussymptomsthatarenoticeablebut3symptomsthatcanleadtoadiagnosisofkidneydiseasearechangesinurination,swellingoffeetandanklesanddecreasedmentalsharpness(startingtoforgetthingsornotknowingasmuchasyouusedto).Inearlystagesonkidneydisease,ahealthydietandmedicationwillkeepitatbay,butwhenitreachesbelow10-15%ofnormaleffectivenessyouwillneedakidneytransplantordialysistostayalive.Highbloodpressureanddiabetesaccountfor66%ofthecauseforkidneydisease.Knowingthis,eathealthyandexercisevigorouslytokeepthetwoundercontrolandyoushouldbefine.
JohnWinnipeg,MB
Kidney Disease
Berger’s Disease
MarshallWinnipeg,MB
Berger’sdiseaseeffectsthearteriesandveinsinboththearmsandlegs.Thediseasecausesyourvesselstobecomeinflamedandclogged.Swellingcanoccurwhenbloodclots.Berger’scandestroyskintissuesleadingtoinfection.Smokersareonlysusceptibletothiscripplingdisease,oncediagnosedifsmokerstodonquititcouldleadtoamputationoflimbs.VarioussymptomscanbenoticedwhenyouhaveBerger’sdisease.Theymaystartwithpaininarmsandlegswhenyourbloodclots(whenresting).Inflammationcouldalsobenoticedalongveinsandarteries.Painfulopensorescouldoccuronhandsfeet.Medicationsthatdilatebloodvesselscanhelpimprovebloodflowinbloodclots.Medicationstostimulateandincrease
growthofnewbloodvesselscanalsobeused.Somepeoplebelieveleechtherapysessionscanbeusedforamputation.Quittingsmokingisalwaysthefirsttreatmentthatshouldbedonesinceitwillonlyfurthermoreworsenit.Notsmokingnicotineproductsistheonlythingthatcanpreventthisdisease.
Kidney Stones HopeWinnipeg,MB
Kidneystonesoccurwhenyoururinecontainsmorecrystal-formingsubstanceslikecalcium,oxalate,anduricacid.Thefluidinyoururinecandilute.Atthesametime,yoururinemaylacksubstancesthatpreventcrystalsfromstickingtogether,creatinganidealenvironmentforkidneystonestoform.
Youmayexperiencesignsorsymptomssuchas,paininsideandback,lowerabdomen,groin,andwhileurinating.Youmayalsoexperiencepinkredorbrownpee,cloudyorfoulsmellingurine,nausea,andvomiting.
Forcertainkidneystonesdependingonsizeandlocationyourdoctormayrecommendaprocedurecalledextracorporealshockwavelithotripsy.ESWLusessoundwavestocreatestrongvibrationsorshockwavesthatbreakthestonesintotinypiecesthatcanbepassedinyoururine.
ToavoidgettingkidneystonesyoucaneatstoneformingfoodsuchasBeets,chocolate,spinach,rhubarb,tea,andmostnutsarerichinoxalate,andcolasarerichinphosphate,bothofwhichcancontributetokidneystones.
Urinary Tract Infection RollynWinnipeg,MB
Aurinarytractinfectionistheresultofbacteriafromyourlargeintestineescapingintotheanusandenteringtheurethra.Thechanceofgettingaurinarytractinfectionisfairlyhighbut,ifyouarefemale,thechanceofgettinganinfectionis1in2.Herearesomesymptomsthatcanhelpyouidentifytheinfection.IfyoufeelaburningsensationwhenurinatingthatcouldbeseenasasignofaUrinaryTractInfection,aswellifyouhavepainorpressureinyourlowerbackorabdomen.Youcanalsofeeltiredorshakyorhavesymptomsofhavingafeverorchill,thishoweverisonlycommononcetheinfectionhasreachedyourkidneys.Ifyouhaveaurinarytractinfectionthereareafewtreatmentoptionsyoucouldtaketoridoftheinfection.Gotothedoctorassoonaspossible,therethey’llaskforaurinesamplewhichwillbetestedforthebacteriafromtheintestines.Theywillthengiveyouantibioticsthatyou’llhavetofinishtoensurethebacteriaaregonecompletely.Ifyouareexperiencepain,thedoctormightprescribepainmedicationtosootheitaswellagoodthingtohaveisaheatingpad.Drinkwatercanhelpflushoutthebacteriafromyoururinarytract.Therearemanywaystopreventthisfromhappeningagain.Youshouldemptyyourbladderfrequently,wipefromthefronttoback,drinklotsofwaterandswitchfrombathstoshowers.
Berger’s Disease KatrielWinnipeg,MB
ThisisakidneydisordercausedbydepositsoftheproteinimmunoglobinA(IgA)insidetheglomeruliwithinthekidney.Theglomerulifilterwastesandexcesswaterfromthebloodandsendthemtotheurinarybladderasurine.Theblockagepreventsthemfromperformingthis.Asaresulttheurinecontainsbloodandproteinsandthereisswellingofthehandsandfeet.SomeofthesymptomsofIgANephropathyare:
• Swellingofthehandsandfeet(edema)• Recurrentupperrespiratoryinfections• BloodandProteinintheurine(HematuriaandProteinuria)
Thiskindofdiseaseiscomplicatedandneedsprecisiontotreat.Therefore,beforetreatinganypatient,ahealthcareprovidermustviewthefollowingfactors:age,overallhealthandpasthealth,thestageofthedisease,theexpecteddurationofthecondition,thepatient’sabilitytohandlespecificmedicines,therapiesormeasuresandlastlythepatient’sopinionorpreference.Someoftheothertreatmentsare:
• Dietchangesthatreducetheintakeoffatsandcholesterol• Quittinghabitssuchassmoking• Havingahighfluidintake
Themosteffectivepreventivemeasureagainstthisdiseaseispreventingupperrespiratoryinfectionsorevencoldsthatcausethisdisease.Otherpreventivemeasuresare:dailyexercisetostrengthenthebody’scondition,ahealthydietandlotsofrestandavoidingintakeofhealthcareproductsandmedicineswhichtakesawaytheburdenonthekidney.
Kidney Stone SimeonWinnipeg,MB
Akidneystoneisahardmassformedinthekidneys,typicallyconsistingofinsolublecalciumcompounds;arenalcalculus.Symptomsthatcanbeusedtodiagnoseforthekidneystoneisthatyoumayfeelseverepaininthesideandback,belowtheribs.Painthatspreadstothelowerabdomenandgroin.Painonurination.Smallerkidneystonescanbepassedthroughyoururine.Butlargerstoneshave4treatmentstogetthemremoved;extracorporealshockwavelithotripsy(ESWL),ureteroscopy,percutaneousnephrolithotomy(PCNL),andopensurgery.ESWListhemostcommonwayoftreatingkidneystonesthatcan’tbepassedthroughurine.Itstartswithusingultrasoundtolocatewherethestoneis.Ultrasoundshockwavesaresenttothestonefromamachinetobreakitdownintosmallerpieces.Thenitcanbepassedthroughtheurine.Ureteroscopyisusedwhenthestoneisstuckintheureter.Startswithalong,thintelescopethroughtheurethraandintothebladder.Thengoestotheureterwherethestoneislocated.Thesurgeoncaneithertrytoremovethestonegentlyusinganothertool,oruselaserenergytobreakitintosmallpieces,soitcanberemovedthroughurination.PCNLisanalternativeprocedureforlargerstones.ItusesathintelescopicinstrumentcalledNephroscope.Asmallcutismadeinthebackandthenephroscopeispassedthroughitandintothekidney.Thestoneiseitherpulledoutorgetsbrokenintosmallerpiecesusingalaserorpneumaticenergy.Opensurgeryforkidneystonesaretherarest.Onlyusedforaverylargestoneorabnormalanatomy.Anincisionismadeintheback,foraccesstotheureterandkidney,thenthestoneisremoved.Peoplecanpreventkidneystonesbymakingchangesintheirfluidintake.Drinkingenoughfluideachdaycouldbethebestwaytpreventmosttypesofkidneystones.
Horseshoe Kidney TaylorWinnipeg,MB
Horseshoekidney,orrenalfusion,isaconditioninwhichyourkidney’sformtogethertocreateonehorseshoeshapedkidney.Thisconditionhappensduringthedevelopment in thewomb. The condition occurs in about 1 in 500 children,mostcommon in males. Some symptoms of a horseshoe kidney are: pain in the belly,nausea,kidneystones,andurinary tract infections.Kidneycancer,althoughrare inchildren,ismorelikelytooccurinhorseshoekidneys.Manydoctorsfindhorseshoekidneys while treating a different condition. Some tests they use to help find ahorseshoe kidney are: ultrasound, intravenous pyelogram (IVP), or magneticresonance imaging (MRI), as well as some blood tests sometimes. There are notmany options for treating horseshoe kidney, some treatments can treat thesymptomsthough.Somecommonproblemswithhorseshowkidneyare:blockageofurineflow,andurineflowingbackwardsfromthebladder,whichbothcanwefixedwithsurgery.Alsopeoplewithhorseshoekidneyare likely to feelmorepainwhenthere’s trauma to the stomach. Childrenwith horseshoe kidney are encouraged towear amedical alert bracelet, to let emergency doctor’s know to be aware of thechance of kidney damage, and not to play contact sports. There is no prevention,peoplewithhorseshoekidneyarebornwithit.Nephrocalcinosis
TommyWinnipeg,MB
NephrocalcinosisalsoknownasAlbright'scalcinosis(calledbyfullerAlbright).Itisatermusedtodescriberenalparenchymalcalcificationonradiology.Itisfindingmedullaryspongekidneyintheupperbodypartofyourchest.Somesymptomsmayinclude,highlevelsofcalciuminyourblood,feverandcold,nauseaandpain,bloodinyoururine,paininthesideofyourbelly/stomach.ProximalRenalTubularAcidosiscanpreventcalciumcloggingupinyourkidneythatleadstonephrocalcinosis.TreatmentforNephrocalcinosisincludestryingtoloweryourcalciumlevels.Youcangetmedicalhelpfromyourdoctorifyouneedhelpwithloweringyourcalciumlevels.