JOURNAL OF VIROLOGYjvi.asm.org/content/36/3/local/admin.pdfJOURNAL OF VIROLOGY VOLUME36 0 NUMBER3 0...
Transcript of JOURNAL OF VIROLOGYjvi.asm.org/content/36/3/local/admin.pdfJOURNAL OF VIROLOGY VOLUME36 0 NUMBER3 0...
JOURNAL OF VIROLOGYVOLUME 36 0 NUMBER 3 0 DECEMBER 1980
EDITORIAL BOARDRobert R. Wagner, Editor-in-Chief (1982)University of Virginia School of Medicine,
Charlottesville
Dwight L. Anderson, Editor (1983)School of Dentistry,
University ofMinnesota,Minneapolis
David T. Denhardt, Editor (1982)University of Western OntarioLondon, Ontario, Canada
Harold S. Ginsberg, Editor (1984)Columbia UniversityNew York, N. Y.
Edward M. Scolnick, Editor (1982)National Cancer Institute
Bethesda, Md.
David Baltimore (1981)Amiya K. Baaerjee (1982)
jeaneth 1. Berns (1982)IH. L Bishop (1982)DavlW9otstein (1982)Michael A. Bratt (1980)Dennis T. Brown (1981)Ahmad 1. Bukhari (1981)Purnell Choppin (1980)John M. Coffin (1980)Richard W. Compans (1982)Geoffrey M. Cooper (1981)Nicbolas R. Cozzarelli (1980)Clive Dickson (1981)Walter Doerfier (1980)Harrison Echols (1981)Elvera Ebrenfeld (1980)Robert N. Eisenaa (1982)Suzanoe U. Emerson (1980)Lynn Enquist (1981)Erw* . Fleissner (1980)S. Jaze Flint (1981)Robert M. Friedman (1982)Larry M. Gold (1982)Hidesaburo Hanafusa (1980)William S. Hayward (1981)John J. Holland (1981)
Nancy Hopkins (1980)Calderon Howe (1982)Alice S. Huang (1981)D. C. Kelly (1982)Tlomas J. Kelly, Jr. (1982)George Khoury (1981)Jonathan A. King (1981)David W. Kingsbury (1982)Lloyd M. Kozloff (1982)Robert M. Knig (1980)Robert A. L i 1981)Richard A. Lerner (1981)Myron Levine (1982)Tomas Lindahl (1981)David M. Livingston (1980)Ronald B. Luftig (1981)Robert MartiDn (1981)Lois K. Miller (1982)Robert C. Miller (1980)Gisela Mosig (1982)Bernard Moss (1980)Joseph S. Pagano (1982)J. Thomas Parsons (1980)Ulf G. Petterson (1980)Lennart Philipson (1981)Peter G. W. Plagemann (1980)Craig R. Pringle (1980)
Fred Rapp (1981)Dan S. Ray (1980)M. E. Reicn (1982)Bernard E. Reilly (1980)Willham S. Robinson (1980)BenardRo (1982)Roland R. Rueckert (1982)Norman P. Salman (1981)Joseph Sambook (1982)Priscila A. Schaffer (1981)Sondra S ger (1980)Phlp A. Sharp (1982)Aaron J. Shatkln (1982)Saul J. Silverstein (1982)Lee D. Simon (1981)Kai Simn (1981)Alan E. Smith (1980)Patricia G. Spear (1981)F. William Studier (1981)Lawrence S. Sturnan (1982)Donald F. Summers (1982)William C. Summers (1980)John M. Taylor (1981)Howard M. Temin (1982)David C. Ward (1980)Ernest Winocour (1982)Julius Youngner (1982)
Giseila Pollock, Acting Managing EditorSusan Birch, Production Editor
1913 I St., NW, Washington, DC 20006
Albert Balows, President (1980-1981)J. Mebsen Joseph, Secretary
The Journal of Virology (ISSN 0022-538X), a publication ofthe American Society for Microbiology, 1913 1 St., NW, Wash-ington, DC 20006, is devoted to the dissemination offundamentalknowledge concerning viruses of bacteria, plants, and animals.Inves ators are invited to submit reports of original research inall areas of basic virology, including biochemistry, biophysics,genetics, immunology, morphology, and physiology. Instructionsto Authors are published in the January issue each year. TheJournal is issued monthly, four volumes per year. The nonmem-ber subscription price is $90 per year, single copies are $8. Themember subscription price is $21 per year. Correspondencerelating to subscriptions, reprints, defective copies, availability ofback issues, lost or late proofs, disposition of submitted manu-
and general editorial matters should be directed to theASS Publications Office, 1913 I St., NW, Washington, DC20006 (area 202 833-9680).
ai* : idbm 119*lkA ,-1 E 11IrA ff,fl ( I fo
EX OFFICIOFrederick C. Neidhardt, President-Elect (1980-1981)
Brinton M. Miller, Treasurer
Second-class postage paid at Washington, DC 20006, and atadditional mailing offices.Made in the U.S.A.Copyright i 1980, American Society for Microbiology.All Rights Reserved.
The code at the top of the first page ofan article in this journalindicates the copyright owner's consent that copies of the articlemay be made for personal use, or for personal use of specificclients. This consent is given on the condition, however, that thecopier pay the stated per-copy fee through the Copyright Clear-ance Center, Inc., P.O. Box 765, Schenectady, New York 12301,for copying beyond that permitted by Sections 107 and 108 ofthe U.S. Copyright Law. This consent does not extend to otherkinds of copying, such as copying for general distribution, foradvertising or promotional purposes, for creating new collectiveworks, or for resale.
Author IndexAAwine, James C., 701
:jBErson, Steven M., 676
Bastow, K. F., 746Battula, Narayana, 709Bearzotti-Le Berre, Monique,
652Bellamy, A. R., 894Bernard, Jacqueline, 652Boettiger, David, 883Brown, Dennis T., 775Buetti, Elena, 734
4ai, Enzo, 816Chowdhury, Kamal, 878Clark, Daniel R., 766,~i~,Fulmer, 872
Cowra, Jon H., 796Cooper, Geoffrey M., 684Courtney, Richard J., 665
lxy, G., 746De, arun K., 847de Kinkelin, P., 652Demsey, Anthony, 872Diggelmann, Heidi, 734Dorsch-Hasler, Karoline, 837
Eberle, R., 665Erwin, Christine, 775
Faras, A. J., 805Feitelson, Mark A., 787
Fujinaga, Kei, 639
Gerlich, Wolfram H., 787Grandgenett, Duane P., 889Groner, Bernd, 734
Halbert, Donald N., 860Hanafusa, Hidesaburo, 676Harris, Tixnothy J. R., 659Harvey, J. D., 894Hayward, William S., 676Heilman, Carole A., 878Howley, Peter M., 878Hu, James, 692Huang, Alice S., 756Hulen, Christian, 633Hynes, Nancy E., 734
Israel, Mark A., 878
Jenkins, Nancy A., 684
Kawka, Douglas, 872Khoury, George, 701Krzyzek, R. A., 805
Labedan, Bernard, 633Lambert, Dennis M., 837Lau, A. F., 805Law, Ming-Fan, 878Lazzarini, Robert A., 796Legault-Demare, Jean, 633
Lodish, Harvey F., 719
Marion, Patricia L., 787Mason, William S., 829Mbuy, Gustave N., 837Minson, A. C., 746Mitchell, R. L., 805
Nayak, Debi P., 847Neel, Benjamin G., 676
Peters, Gordon G., 692Pignatti, Pier F., 816Pons, Marcel W., 837Porter, Mary, 719
Ralph, S. J., 894Rao, Donald D., 756Raskas, Heschel J., 860Rentier-Delrue, Francoise, 878Robinson, William S., 787Rosenberg, Naomi E., 766
Sawada, Yukiharu, 639Schiff, Ron D., 889Seal, Geeta, 829Spector, David J., 860Steimer, Kathelyn S., 883Summers, Jesse, 829
Takemoto, Kenneth K., 878Todaro, George J., 709
Wildy, P., 746Witte, Owen N., 766
ACKNOWLEDGMENT
The following have served as invited special reviewers for the Journal during 1980, and their
help is greatly appreciated.
Stuart AaronsonJosef AloniJames AlwineChristian AnfinsenRalph B. ArlinghausJ. Thomas AugustRichard AxelJohn P. BaderCarrado BaglioniL. Andrew BallClaudio BascilicoRobert BassinKaren BeemonThomas BenjaminPeter B. BergetAlan BernsteinEdward BirkenmeierJ. Michael BishopKlaus BisterDavid BoettingerMichael BotchanSidney BreeseSean BrennanDoris BucherClarence A. BullerJanet ButelR. CallahanAllan M. CampbellRobert CardiffEsther ChangRobert ChanockCraig CohenMarc CollettDonald L. CourtJohn DahlbergJames E. DarnellVittorio DefendiE. DeHarvinAlbert DeLeuMelvin DePamphilisMichael DexterRavi DharHeidi DiggelmannGiampiero di MayorcaDino DinaJoseph DipaoloGideon DreyfusEdward J. DuboviPeter H. DuesbergWalter EckhartJohn ElderRay EricksonMary K. EstesLeonard EvansHung FanAnthony J. FarasBernard FieldsPeter FischingerWilliam FolkC. Fred FoxHeinz Fraenkel-ConratRichard M. Franklin
Mike FriedRobert J. GaloE. Peter GeiduschekJohn GemnRaymond GildenRobert GoldbergNeil GoldmanMichael GottesmanT. GrafAngus F. GrahamDuane GrandgenettAllan GranoffMaurice GreenBeverly GriffinNeal B. GromanPeter GrussAshley HaaseGordon HagerStephen C. HarrisonJanet HartleyWilliam HaseltineIan H. HolmesJerard HorowitzPeter HowleyS. HughesAnthony HunterJames IhleMark IsraelGilbert JayGeorge JohnsonRichard JohnsonWolfgang K. JoklikDavid KabatPaul J. KaesbergRobert KamenWilliam KamenC. Yong KangAlbert KapikianAlbert KaplanKathleen KennedyS. I. T. KennedySaul KitEdward KuffChing-Juh LaiMichael LaiLloyd LawPaul LebowitzPeter LengyelArnold J. LevineA. LindbergMaxine LinialPaul S. LovettRex E. LovrienDouglas LowyRoderick MacLeodManley MandelJack ManiloffJames ManleyStuart MarcusG. Steven MartinMalcolm A. MartinHeather D. Mayor
Philip McAllisterD. James McCorquodaleJoseph MelnickTrudy G. MorrisonK. MulliniFrederick A. MurphyJohn R. MurphyDaniel NathansPaul E. NeimanRobert NewarthAbner L. NotkinsRobert NowinskiStephen O'BrienPaul O'DonnellMichael B. A. OldstonePeter M. PaleseAmon PanetTakis PapasArthur PardeeWade ParksIra PastanJanice PeroJacques PerraultSidney PestkaWilliam A. Petri, Jr.Ralf F. PettersonPaula PithaRobert PollackAlan R. PriceCarol PrivesAl RabsonUlf RappJames A. RawlesJohn ReeveDaniel RifldinRichard RobertsBetty Jo RobertsonHarriett RobinsonJohn K. RoseJeff RosenNaomi RosenbergEllen RothenbergWallace P. RoweSandra RuscettiM. SarngadharanAndreas S. ScheidCharles ScherrMilton SchlesingerJeffrey SchlomManfred SchweigerBartholomew M. SeftonRoland SeifPeter ShankJoel B. SheffieldThomas ShenkCharles SherrThomas ShihRobert W. SimpsonMaxine SingejAnna Skalka<D. Peter SnustadMitchell Sogin
S0
William A. StarkJesse SummerRaquel SussmanWaclaw SzybalskiPeter TegtmeyerSatvir TevethiaRobert E. ThachGeorge TodaroThomas A. TrautnerStephen TronickPhilip TsichlisGeorge Vande WoudeJames L. Van EttenHarold Varmus
Leland VelicerAnne K. VidaverPeter K. VogtVolker VogtDon WalkerDuard L. WalkerL. H. WangHuber R. WarnerRobert E. WebsterRobert A. WeinbergI. B. WeinsteinPeter WeisbeekSherman WeissmanHeiner Westphal
Sue WicknerEvelyn WilkinS. G. WilkinsonMark WillinghamGary A. WilsonEckard WimmerOwen WitteRobert YangWen YangHamish YoungHoward A. YoungJack J. ZakowskiPaul ZamecnikHarold Zur Hausen
AUTHOR INDEX
VOLUME 36
AI-Shaiiwari Abdul J. N., 120Alwine, James, 143Alwine, James C., 701Anderson, Dwight L., 236Anderson, Steven M., 676
Bacchetti, Silvia, 361Bacheler, L. T., 254Baltimore, David, 547Baluda, M. A., 317, 325Barwise, A. H., 224Bastow, K. F., 746Battula, Narayana, 709Bearzotti-Le Berre, Monique,652
Bellamy, A. R., 894Bernard, Jacqueline, 652Berns, Anton J. M., 254Bia, Frank J., 245Bishop, J. Michael, 50, 575Bister, Klaus, 617Boettiger, David, 883Bosselman, R. A., 254Briskin, M. J., 325Brown, Dennis T., 775Bucher, D. J., 586Buetti, Elena, 734Burnette, W. Neal, 280
Cardiff, Robert D., 109Carlson, Karin, 1Cassai, Enzo, 816Cassingena, Rolando, 295Chang, Esther H., 408Chattopadhyay, Sisir K., 499Chen, J. H., 162Chowdhury, Kamal, 566,878Clark, Daniel R., 766Coca-Prados, M., 353Coffnan, Robert, 547Cohen, Gary H., 429Collins, Fulmer, 872Condra, Jon H., 796Cooper, Geoffrey M., 684Copeland, Terry D., 115Courtney, Richard J., 665Curtis, Peter J., 133
Darby, G., 746Davis, J. F., 586De, Barun K., 847DeFeo, Deborah, 408de Kinkelin, P., 652DeLorbe, William J., 50Demsey, Anthony, 872Diebold, Mary A., 541
Diggelmann, Heidi, 734di Mayorca, Giampiero, 480Dimock, Kenneth, 361Dixon, Richard A. F., 189Doerfiler, W., 22Doerfler, Walter, 41Dorsch-Hasler, Karoline, 837Duesberg, P. H., 591Duesberg, Peter H., 617
Eberle, R., 665Eckhart, Walter, 125Ehrenfeld, Ellie, 387Eick, Dirk, 41Eisenberg, Roselyn J., 429Eisenman, Robert N., 62Ellis, Ronald W., 408Emerson, Suzanne U., 309Enjuanes, Luis, 299Erwin, Christine, 775
Fan, H., 254Fanning, Thomas G., 109Fanshier, Lois, 575Faras, Anthony J., 236, 805Feitelson, Mark A., 787Fenno, James, 280Fong, Caroline K. Y., 245Friis, R. R., 22Fujinaga, Kei, 337, 639
Garon, Claude F., 566Gerlich, Wolfram H., 787Gerling, David, 264Gershowitz, Alan, 601Gilmer, Tona M., 271Goldbach, Rob, 366Goldman, Neil, 143Gomatos, Peter J., 556Goodman, Howard M., 50Grandgenett, Duane P., 115, 889Green, Michael R., 79Gregoriades, Anastasia, 470Griffin, James D., 488Grigoriev, V. B., 586Groman, N. B., 526Groner, Bernd, 734Gruss, Peter, 143
Haas, Martin, 606Haberer, Klaus, 264Halbert, Donald N., 860Hall, Dwight H., 103Hanafusa, Hidesaburo, 676Harris, Timothy J. R., 659Harvey, J. D., 894
i
Hawke, Mary, 506Hayward, William S., 676Heilman, Carole A., 395, 878Highfield, Peter E., 271Hillyard, R. L., 325Holland, John J., 627Horak, Ivan, 299Horodyski, Frank M., 627Horwich, Arthur, 125Howley, Peter M., 395, 878Hsiung, G. D., 245Hsu, M.-T., 353Hu, James, 692Huang, Alice S., 756Hulen, Christian, 633Hunsmann, G., 291Hynes, Nancy E., 734
Ihle, James N., 299Ishimoto, Akinori, 18Israel, Mark A., 395, 566, 878Ito, Yoshiaki, 566
Jay, Gilbert, 143Jenkins, Nancy A., 684Johnson, K. M., 465Jongstra, Jan, 606Jovanovich, Susan, 595
Kawka, Douglas, 872Keith, Jerry M., 601Kelley, J. Michael, 309Kelly, D. C., 224Kennedy, S. Ian T., 440Kharitonenkov, I. G., 586Khoury, George, 143, 701Kieff, Elliott, 506Kiggans, James O., Jr., 181Kiley, M. P., 465King, Walter, 506Kingpford, Laura, 309Klimenko, S. M., 586Koop, Allen H., 125Krueger, Robert G., 533, 541Krzyzek, Richard A., 236, 805
Labedan, Bernard, 633Lai, M. H. T., 254Lambert, Dennis M., 837Lander, Marilyn R., 499Lau, A. F., 805Lavialle, Christian, 295Law, Ming-Fan, 395,878Iarini, Robert A., 796Lee, John C., 299Lee, W.-H., 591
ii AUTHOR INDEX
Lee, Wen-Hwa, 617Legault-Demare, Jean, 633Leung, Wai-Choi, 361Light, Susan E., 566Linial, Maxine, 62, 280, 450Livingston, David M., 488Lodish, Harvey F., 719Long, Deborah, 429Lowy, Douglas R., 408Luciw, Paul A., 50
Maandag, E. C. Robanus, 254Maniloff, Jack, 264Marion, Patricia L., 787Martin, G. S., 591Maryak, Jean M., 408Mason, William S., 62, 829Mbuy, Gustave N., 837McKennett, M. A., 254Minson, A. C., 746Mitchell, R. L., 805Moore, N. F., 224Morrison, T. G., 171Moscovici, Carlo, 575Moss, Bernard, 601Muzyczka, Nicholas, 611
Nayak, Debi P., 847Neel, Benjamin G., 676
O'Callaghan, Dennis J., 204Oroszlan, Stephen, 115
Parsons, J. Thomas, 271Pass, Franklin, 236Pater, Alan, 480Pater, Mary M., 480Pedrali-Noy, Guido, 457Peters, Gordon G., 692Pignatti, Pier F., 816Pons, Marcel W., 837Porter, Mary, 719Pritchett, Randall F., 152Puma, John P., 109
Raab-Traub, Nancy, 506Rabin, M., 526Rafield, Lori F., 271Ralph, S.-J., 894Rao, Donald D., 756Raskas, Heschel J., 860Rawlins, Dan R., 611Regnery, R. L., 465Rentier-Delrue, Francoise, 878Reynolds, Fred H., Jr., 374Rezelman, Geertje, 366Rhoades, Marc, 622Richards, Oliver C., 387Robinson, P. J., 291Robinson, Robin A., 204Robinson, William S., 787Roeder, Robert G., 79Rohrschneider, Larry, 280Rosenberg, Naomi E., 766Rotter, Varda, 547Rowe, Wallace P., 499Rubin, Harvey, 488Russell, Diane L., 103
Sargent, R. Geoffrey, 103Sarkar, Nurul H., 556Sawada, Yukiharu, 639Schaffer, Priscilla A., 189Schiff, Ron D., 889Schirrmacher, V., 291Schneider, J., 291Schwartz, Joanna, 622Scolnick, Edward M., 408Seal, Geeta, 829Seif, Roland, 421Shank, Peter R., 450Shih, Thomas Y., 408Showe, Michael K., 220Simmons, Daniel T., 519Simpson, D., 171Smiley, James R., 361Smith, Paul F., 120Souza, L. M., 317, 325Spadari, Silvio, 457Spangler, Gregory J., 488Spector, David J., 860
Spilling, C. R., 224Spriggs, Dale R., 533, 541Stabel, S., 22Stabel, Silvia, 41Stamatos, Nicholas M., 556Steimer, Kathelyn S., 883Stephenson, John R., 374Stern, David F., 440Suarez, Horacio G., 295Summers, Jesse, 829Summers, William C., 245
Takemoto, Kenneth K., 878Thomas-Powell, Ann L., 506Todaro, George J., 709Traub, Franz, 220Trofatter, Kenneth F., 103
Vance, Ralph B., 204Van de Ven, Wim J. M., 374van Driel, Roel, 220Van Kammen, Albert, 366Varmus, Harold E., 50v.d. Putten, H., 254Vennstrom, Bjorn, 575Verma, Inder M., 254Vidali, G., 353Villarreal, Luis P., 595
Wagner, Robert R., 93Wahl, Jeffrey M., 622Walker, I. O., 224Watts, Susan L., 236Wiktor, Tadeusz J., 133Wildy, P., 746Witte, Owen N., 547, 766Wunner, William H., 133
Yang, Den-Mei, 181Yang, Wen K., 181Yoshida, Kouichi, 337Young, Howard A., 408
Zakomirdin, J. A., 586Zakowski, Jack J., 93
J. VIROL.
SUBJECT INDEX
VOLUME 36
Abelson murine leukemia virusantibodies against P50, 547mutants deficient in kinase activity and lymphoid
cell transformation, 766P120-associated protein kinase activity, 374transformation-defective mutants, 374
Acholeplasma laidlawiimycoplasma virus MVL3, 264
Acholeplasma laidlawii strain JAlcellular components, 120mycoplasma virus type 2, 120
Adeno-associated virusgenome transcripts, 79mapping of major RNAs, 79
Adenovirushuman cell line 293, 860regulation of integrated sequences, 860
Adenovirus type 7DNA fragment-transformed cells, 337unique mRNA species from early region 1, 337
Adenovirus type 12DNA integration sites, 22hamster cell line T637 revertants as tools in analysis
of integration patterns, 41mRNA mapping, 639transformed hamster cells and hamster tumor cells,
22Adenovirus type 2-simian virus 40
chimeric splice junction, new, 143hybrid viral mRNA, 143
AKR virusendogenous ecotropic virus ofMus musculus molos-sinu, 499
Amber codonconstruction in simian virus 40 T-antigen gene, 611site-directed mutagenesis, 611
Amino acid sequence analysisavian myeloblastosis virus reverse transcriptase sub-
units, 115Anogenital wartshuman papillomavirus, 236
Aphidicolinherpes simplex virus DNA polymerase inhibition,
457vaccinia virus DNA polymerase inhibition, 457
Aphthovirusesfoot-and-mouth disease viruses, 659RNA nucleotide sequences, 659
Asymmetric recombinationnondefective Rous sarcoma virus, 591
Avian acute leukemia virusesphosphorylation of nonstructural proteins, 617
Avian erythroblastosis virusmolecular cloning of genome, 575mRNA's, 676oncogenic virus recovery, 575transfection of chicken cells, 575
Avian Fujinami sarcoma virusphosphorylation of nonstructural proteins, 617
Avian infectious bronchitis virusmapping intracellular RNA species to genome, 440multiplication strategy, 440
Avian myeloblastosis virusacute myeloblastic leukemia-associated restriction
endonuclease fragments, 317amino acid sequence analysis of reverse transcrip-
tase subunits, 115chicken cells, 162endogenous, 162genome identification, 317, 325restriction endonuclease analysis of DNA from A
proviral recombinants and leukemic myeloblastclones, 325
Avian oncovirusmutant (SE21Q16) deficient in genomic RNA, 450provirus deletion, 450
Avian retroviruspp32 DNA endonuclease, partial phosphorylation in
vivo, 889Avian retrovirusespolymerase proteins, synthesis and processing, 62wild-type and mutant, 62
Avian sarcoma viruscircular DNA molecules, 50molecular cloning and characterization, 50molecular cloning of closed circular DNA, 271nonpermissive and permissive cells, 805protein kinase activity, pp6OsC and src, 805recombinant clones, structural and biological char-
acterization, 271reverse transcriptase, 692selective packaging of tRNA's, 692
Baboon type C viral DNAinfectious, 709integration sites, 709physical map, 709
Bacteriophage lambdaMoloney murine leukemia viral DNA, molecular
cloning, 254Bacteriophage T4
cytosine-containing DNA, 1endonuclease SalI, KpnI, BglI, and BamHI, 1gene 63, suppressors of mutations, 103genetic map and map of cleavage sites, 1preheat proteinase zymogen, 220RNA ligase, 103tail fiber attachment, 103
Bacteriophage T5deletion mutant, 622heterogeneity, 633second-step-transfer DNA injection, 633
BALB/c miceMoloney leukemia virus, 299
.m
iv SUBJECT INDEX
splenic T-cell lymphoma cell line, 299unique defective type C virus, 299
BALB/c myeloma retrovirusesimmunological analysis, 533mink cell focus-inducing activity, 541peptide mapping, 533ppl2 structural protein, 533
BHK-21 cellsSindbis virus membrane protein distribution, 775
Bottom component RNAcowpea mosaic virus, 366cowpea protoplasts, 366
Chicken cellsendogenous avian myeloblastosis virus information,
162Circular DNA molecules
avian sarcoma virus, 50molecular cloning and characterization, 50
Coronavirusavian infectious bronchitis virus, mapping intracel-
lular RNA species to genome, 440multiplication strategy, 440
Corynebacteriophagesheteroimmune, 526superinfection exclusion, 526
Cowpea mosaic virusbottom component RNA expression, 366cowpea protoplasts, 366
Cowpea protoplastsbottom component RNA expression, 366cowpea mosaic virus, 366
CV1 cellsnuclear transcript leakage, 595simian virus 40-infected, 595
Cyanogen bromide-cleaved peptidescarbohydrate content, 309vesicular stomatitis virus glycoprotein, 309
Cycloheximideherpes simplex virus thymidase kinase transcripts,
361CytomegalovirusDNA nucleotide sequence heterogeneity, 152strains Towne and AD169, 152
Cytosine-containing DNAbacteriophage T4, 1
Defective interfering particlesvesicular stomatitis virus, 627vesicular stomatitis virus RNA synthesis, 756
Deletion mutantbacteriophage T5, 622
Densonucleosis virusstructural proteins, 224
Dinucleotide sequencesvaccinia virus mRNA's, 601
DNA cloninggenomic, 395human papilloma virus, 395
DNA fragmentcloned, 566oncogenic potential, 566pBR322, 566polyoma virus, 566
J. VIROL.
DNA injectionbacteriophage T5, 633second-step-transfer, 633
DNA integration sitesadenovirus type 12, 22transformed hamster cells and hamster tumor cells,
22DNA nucleotide sequence heterogeneity
cytomegalovirus strains Towne and AD169, 152DNA polymerases
aphidicolin inhibition, 457herpes simplex virus, 457vaccinia virus, 457
DNA-protein complexesherpes simplex virus, 816
Ebola virusvirion nucleic acid, 465
Endonucleases Sall, KpnI, Bgil, and BamHIbacteriophage T4 cytosine-containing DNA, 1genetic map and map of cleavage sites, 1
Envelope assembly mutantRous sarcoma virus, 883
Epstein-Barr virusrestringently infected, growth-transformed cell line,
506viral RNA, 506
Equine herpesviruseshamster embryo cells, 204oncogenic transformation, 204
Equine herpesvirus type 1persistent infection and oncogenic transformation ofhamster embryo cells, 204
Escherichia colipolyoma small T antigen, 125
Focus formationecotropic murine leukemia viral genome, 18S+L- mink cells, 18
Foot-and-mouth disease virusesRNA nucleotide sequences, 659
Friend murine leukemia viruspossible cell surface receptor, 291viral envelope glycoprotein complexes, 291
Gene 63bacteriophage T4, 103RNA ligase, 103suppressors of mutations, 103tail fiber attachment, 103
Glycoproteins gA and gBherpes simplex virus type 1, 665
Glycoproteins gD and gCherpes simplex virus type 1, 429synthesis and processing, 429
GPXVnew endogenous herpesvirus of guinea pigs, 245
GR micemouse mammary tumor virus, selective amplifica-
tion, 109Ground squirrel hepatitis virus
surface antigens, 787Guinea pigs
VOL. 36, 1980
herpesvirus, new endogenous, 245
Hamster cell line T637adenovirus type 12-transformed, 41revertants as tools in analysis of integration pat-
terns, 41Hamster cells
adenovirus type 12 DNA integration sites, 22transformed, 22
Hamster embryo cellsoncogenic transformation by equine herpesvuses,
204Hamster tumor cells
adenovirus type 12 DNA integration sites, 22Harvey murine sarcoma virus
rat genetic sequences, dual evolutionary origin, 408HeLa cells
defective interfering influenza viruses, 847persistent infection, 847
Hepatitis B virusPekin ducks, 829
Herpes simplex viruscycloheximide, 361DNA polymerases, mechanism of inhibition by aphi-
dicolin, 457DNA-protein complexes, 816thymidine kinase transcripts, 361
Herpes simplex virus type 1glycoproteins gA and gB, 665glycoproteins gD and gC, synthesis and processing,
429immediate early protein VP175, 189temperature-sensitive mutants, fine-structure map-
ping and functional analysis, 189Herpes simplex virus type 2
reversion to thymidine kinase-negative phenotype,746
thymidine kinase gene-carrying cells, 746Herpesvirus
biological and molecular characterization of newendogenous, 245
guinea pigs, 245Histone modifications
simian virus 40 nucleoprotein complexes, intracel-lular forms, 353
Human amnion cellscloned human polyoma virus JC DNA, 878
Human cell line 293adenovirus-transformed, 860
Human hepatitis B virusPekin ducks, 829surface antigens, 787
Human papilloma viruscloning of genomic DNAs, 395homologous polynucleotide sequence analysis, 395
Human papovavirusRF virus, arrangement of the genome, 480
Human polyoma viruscloned JC DNA, 878human amnion cells, 878
Hybrid viral mRNAadenovirus type 2-simian virus 40, 143chimeric splice junction, new, 143
Influenza
SUBJECT INDEX v
M protein interaction with viral lipid and phospha-tidylcholine vesicles, 470
Influenza virusM-protein incorporation into liposomes, 586
Influenza virusesdefective interfering, 847MDBK and HeLa cells, 847persistent infection, 847
5-Iodo-2'-deoxyuridine and mitomycin Ccooperative effect, 295simian virus 40-Chinese hamster kidney cell inter-
action, 295
JC virushuman amnion cell transformation, 878
Leukemiaacute myeloblastic, 317, 325avian myeloblastosis virus genome, 317, 325restriction endonuclease analysis of DNA, 325restriction endonuclease fragments, 317
Lymphomagenesisabrogation, 606radiation leukemia virus-induced, 606
MDBK cellsdefective interfering influenza viruses, 847persistent infection, 847
Membrane-associated proteinslocalization by hydrophobic membrane probes and
cross-linking reagents, 93vesicular stomatitis virus, 93
Mink cell focus-inducing activityBALB/c myeloma retroviruses, 541
Mink S+L- cellsecotropic murine leukemia viral genome, 18focus formation, 18
Minus-strand RNA3' end, 387heterogeneity, 387poliovirus replicative form, 387
Molecular cloningavian erythroblastosis virus genome, 575avian sarcoma virus closed circular DNA, 271bacteriophage lambda, 254Moloney murine leukemia viral DNA, 254oncogenic virus recovery, 575recombinant clones, structural and biological char-
acterization, 271transfection of chicken cells, 575
Moloney leukemia virusBALB/c mice, 299splenic T-cell lymphoma cell line, 299unique defective type C virus, 299
Moloney murine leukemia virusmolecular cloning ofDNA in bacteriophage lambda,
254Mouse mammary tumor virusGR mice, 109proviral DNA characterization, 734selective amplification, 109site-specific molecular clones, 734
M proteininfluenza, 470
vi SUBJECT INDEX
viral lipid and phosphatidylcholine vesicles, 470M-protein
influenza virus, 586mRNA mapping
adenovirus type 12, 639mRNA's
avian erythroblastosis virus, 676mRNA species
adenovirus type 7 early region 1, 337unique, 337
mRNA translationrabies virus, 133Xenopus laevis oocytes, 133
Multiplication strategycoronaviruses, 440RNA-containing viruses, 440
Murine leukemia virusecotropic, 18focus formation by S+L- mink cells, 18
Murine sarcoma viruscore polyprotein cleavage, 872defective particles, structure of and alterations to,
872envelope proteins, 872
Murine type C retroviruscovalently closed circular DNAs, 181cycloheximide-treated cells, 181
Mus musculus molossinusAKR virus, 499endogenous ecotropic virus, 499
Mycoplasma virus MVL3Acholeplasma laidlawii, 264adsorption, capping, and release, 264
Mycoplasma virus type 2Acholeplasma laidlawii strain JAl cellular com-
ponents, 120
Newcastle disease virusglycoprotein synthesis, stability, and cleavage in
absence of glycosylation, 171Nonstructural proteins
avian acute leukemia viruses, 617avian Fujinami sarcoma virus, 617phosphorylation, 617
Nuclear transcriptsleakage in simian virus 40-infected CV1 cells, 595
Nucleic acidsrespiratory syncytial virus, 837
Nucleocapsid assemblyvesicular stomatitis virus-infected permeable cells,
796Nucleoprotein complexes
histone modifications, 353simian virus 40 intracellular forms, 353
Nucleotide sequencesaphthovirus RNAs, 659foot-and-mouth disease virus RNAs, 659
Oncogenic transformationequine herpesviruses, 204hamster embryo cells, 204
P50Abelson murine leukemia virus-induced tumors, 547
antibodies, 547Papillomavirus
anogenital warts, 236human, 236
Papovavirushuman, 480RF virus, arrangement of the genome, 480Tau antigen characterization, 519
pBR322polyoma DNA fragment, 566
Pekin ducksvirus related to human hepatitis B virus, 829
Phosphorylationavian retrovirus pp32, 889
Poliovirusminus-strand RNA, 3'-end heterogeneity, 387replicative form, 387
Polycytidylate-dependent RNA polymerase activitysmall reovirus-specific particle, 556
Polymerase proteinsavian retroviruses, wild-type and mutant, 62synthesis and processing, 62
Polynucleotide sequence analysishomologous, 395human papilloma virus, 395
Polyoma viruscell transformation, 421cleavage with BamHI and EcoRI, 566cloned DNA fragment oncogenic potential, 566cloned human JC DNA, 878early gene region, 566Escherichia coli, 125human amnion cells, 878pBR322, 566small T antigen, 125
ppl2BALB/c myeloma retroviruses, 533immunological analysis, 533peptide mapping, 533
pp32 DNA endonucleaseavian retrovirus, 889partial phosphorylation in vivo, 889
Protein kinase activityAbelson murine leukemia virus transformation-de-
fective mutants, 374avian sarcoma virus-infected cells, 805impaired P120-associated, 374pp60 and src, 805
Protein synthesistranslational control, 719vesicular stomatitis virus infection, 719
Proviral DNAcharacterization with site-specific molecular clones,
734mouse mammary tumor virus, 734
Provirusesexogenously acquired, 684Rous-associated virus-0, 684
Rabies virusmRNA translation, 133Xenopus laevis oocytes, 133
Radiation leukemia virus
J. VIROL.
VOL. 36, 1980
lymphomagenesis abrogation, 606Rainbow trout
viral hemorrhagic septicemia, 652Rat genetic sequences
dual evolutionary origin, 408Harvey murine sarcoma virus, 408
ReceptorsFriend murine leukemia virus, 291
Reovirusparticle with polycytidylate-dependent RNA po-
lymerase activity, 556subunit structure of spike, 894
Replicationvesicular stomatitis virus-infected permeable celLs,
796Replicative form
minus-strand RNA, 3'-end heterogeneity, 387poliovirus, 387
Respiratory syncytial virusnucleic acids, 837
Retroviruscovalently closed circular DNAs, 181cycloheximide-treated cells, 181murine type C, 181
RetrovirusesBALB/c myeloma, 533mink cell focus-inducing activity, 541peptide mapping and immunological analysis of
ppl2, 533Reverse transcriptase
avian sarcoma virus, 692packaging of tRNA's, 692
Reverse transcriptase subunitsamino acid sequence analysis, 115avian myeloblastosis virus, 115
RF virusgenome arrangement, 480
RNA expressionbottom component, 366cowpea mosaic virus, 366cowpea protoplasts, 366
RNA ligasebacteriophage T4 gene 63, 103
RNA synthesisdefective interfering particle transcription and rep-
lication, 756vesicular stomatitis virus, 756
Rous-associated virus-0exogenously acquired proviruses, 684
Rous sarcoma virusasymmetric recombination between deletion mu-
tants, 591envelope assembly mutant, 883nonconditional mutants, 280nondefective, 591viral glycoproteins, synthesis and processing, 280
Simian virus 40amber codon construction by site-directed mutagen-
esis, 611CV1 celLs, 595histone modification, 353low-molecular-weight virus-encoded T antigen, 488nuclear transcript leakage, 595
SUBJECT INDEX vui
nucleoprotein complexes, intracellular forms, 353small RNA mapping and characterization of synthe-
sis, 701spliced and unspliced late 19S RNAs, 595T-antigen gene, 611Tau antigen characterization, 519
Simian virus 40-Chinese hamster kidney cell interac-tion
5-iodo-2'-deoxyuridine and mitomycin C coopera-tive effect, 295
virus replication, 295Sindbis proteinsmembrane association, 775
Sindbis virusmembrane protein distribution, 775wild-type virus- and maturation-defective mutant-
infected BHK-21 cells, 775Small T antigenEscherichia coli, 125polyoma virus, 125
Spike proteinreovirus, 894
Superinfection exclusionheteroimmune corynebacteriophages, 526
Surface antigensground squirrel hepatitis virus, 787human hepatitis B virus, 787
Tail fiber attachmentbacteriophage T4 gene 63, 103
T antigenlow-molecular-weight, 488simian virus 40-transformed cells, 488
Tau antigenscharacterization, 519papovavirus-transformed cells, 519simian virus 40-infected monkey cells, 519uninfected monkey cells, 519
T-cell lymphoma cell lineMoloney leukemia virus-induced splenic, 299unique defective type C virus, 299
Temperature-sensitive mutantsfine-structure mapping, 189functional analysis, 189herpes simplex virus type 1 immediate early proteinVP175, 189
Thymidine kinase geneherpes simplex virus type 2, 746reversion to thymidine kinase-negative phenotype,
746Thymidine kinase transcripts
cycloheximide, 361herpes simplex virus, 361
Transformation-defective mutantsAbelson murine leukemia virus, 374impaired P120-associated protein kinase activity,
374Translational control
protein synthesis, 719vesicular stomatitis virus infection, 719
tRNA packagingavian sarcoma virus, 692reverse transcriptase, 692
Type C virus
viii SUBJECT INDEX
Moloney leukemia virus-induced splenic T-cell lym-phoma cell line, 299
unique defective, 299
Vaccinia virusdinucleotide sequences, 601DNA polymerases, mechanism of inhibition by aphi-
dicolin, 457mRNA's synthesized in vitro, 601
Vesicular stomatitis viruscyanogen bromide-cleaved peptides, 309defective interfering particles, 627, 756glycoprotein, 309membrane-associated proteins, localization by hy-
drophobic membrane probes and cross-linking re-agents, 93
nucleocapsid assembly, 796permeable cells, 796persistently infected cells, 627replication, 796RNA synthesis, 756
transcription and replication, 756translational control of protein synthesis, 719
Viral DNAinfectious baboon type C, 709integration, 709physical map, 709
Viral glycoproteinssynthesis and processing in Rous sarcoma virus
nonconditional mutants, 280Viral hemorrhagic septicemia
polypeptide synthesis, 652rainbow trout, 652thermoresistant virus variant, 652wild-type virus strain, 652
Virion nucleic acidEbola virus, 465
VP175herpes simplex virus type 1, 189
Xenopus laevisrabies mRNA translation in oocytes, 133
J. VIROL.
JOURNAL OF VIROLOGYVOLUME 36 0 1980
EDITORIAL BOARDRobert R. Wagner, Editor-in-Chief(1982)University of Virginia School ofMedicine,
Charlottesville
Dwight L. Anderson, Editor (1983)School of Dentistry,
University of Minnesota,Minneapolis
DavW T. Denhardt, Editor (1982)University of Western OntarioLondon, Ontario, Canada
Harold S. Ginsberg, Editor (1984)Columbia UniversityNew York, N. Y.
Edward M. Scolnick, Editor (1982)National Cancer Institute
Bethesda, Md.
David Baltimore (1981)Amiya K. Banerjee (1982)Kenneth 1. Berms (1982)David H. L. Bishop (1982)David Botstein (1982)Michael A. Bratt (1980)Dennis T. Brown (1981)Abmad 1. Bukhari (1981)Purnell Cboppin (1980)John M. Coffin (1980)Richard W. Compans (1982)Geoffrey M. Cooper (1981)Nicholas R. Cozzarelli (1980)Clive Dickson (1981)Walter Doerfler (1980)Harrison Echols (1981)Elvera Ehrenfeld (1980)Robert N. Eisenman (1982)Suzanne U. Emerson (1980)Lynn Enquist (1981)Erwin J. Fleissner (1980)S. Jane Flint (1981)Robert M. Friedman (1982)Larry M. Gold (1982)Hidesaburo Hanafusa (1980)William S. Hayward (1981)John J. Holland (1981)
Nancy Hopkins (1980)Calderon Howe (1982)Alice S. Huang (1981)D. C. Kelly (1982)Thomas J. Kelly, Jr. (1982)George Khoury (1981)Jonathan A. King (1981)David W. Kingsbury (1982)Lloyd M. Kozioff (1982)Robert M. Krug (1980)Robert A. Lazzarini 1981)Richard A. Lerner (1981)Myron Levine (1982)Tomas Lindahl (1981)David M. lvingston (1980)Ronald B. Luftig (1981)Robert Martin (1981)Lois K. Miller (1982)Robert C. Miller (1980)Gisela Mosig (1982)Bernard Moss (1980)Joseph S. Pagano (1982)J. Thomas Parsons (1980)Ulf G. Petterson (1980)Lennart Philipson (1981)Peter G. W. Plageman (1980)Craig R. Pringle (1980)
Fred Rapp (1981)Dan S. Ray (1980)M. E. Reichmann (1982)Bernard E. Reilly (1980)William S. Robinson (1980)Bernard Rolzman (1982)Roland R. Rueckert (1982)Norman P. Salzman (1981)Joseph Sambrook (1982)Priscilla A. Schaffer (1981)Sondra Schlesinger (1980)Phillip A. Sharp (1982)Aaron J. Shatkin (1982)Saul J. Silverstein (1982)Lee D. Simon (1981)Kd Simons (1981)Alan E. Smith (1980)Patricia G. Spear (1981)F. William Studier (1981)Lawrence S. Sturman (1982)Donald F. Summers (1982)WEUam C. Summers (1980)John M. Taylor (1981)Howard M. Temin (1982)David C. Ward (1980)Ernest Winocour (1982)Julius Youngner (1982)
Gisella Polock, Acting Managing EditorSusan Birch, Production Editor
1913 I St., NW, Washington, DC 20006
Albert Balows, President (1980-1981)J. Mehsen Joseph, Secretary
The Journal of Virology (ISSN 0022-538X), a publication ofthe American Society for Microbiology, 1913 I St., NW, Wash-ington, DC 20006, is devoted to the dissemination offundamentalknowledge concerning viruses of bacteria, plants, and animals.Investigators are invited to submit reports of original research inall areas of basic virology, including biochemistry, biophysics,genetics, immunology, morphology, and physiology. Instructionsto Authors are published in the January issue each year. TheJournal is issued monthly, four volumes per year. The nonmem-ber subscription price is $90 per year; single copies are $8. Themember subscription price is $21 per year. Correspondencerelating to subscriptions, reprints, defective copies, availability ofback issues, lost or late proofs, disposition of submitted manu-scripts, and general editorial matters should be directed to theASM Publications Office, 1913 I St., NW, Washington, DC20006 (area 202 833-9680).
EX OFFICIOFrederick C. Neidhardt, President-Elect (1980-1981)
Brinton M. Miller, Treasurer
Second-class postage paid at Washington, DC 20006, and atadditional mailing offices.Made in the U.S.A.Copyright i) 1980, American Society for Microbiology.All Rights Reserved.
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Volume 36 Contents for October 1980 Number 1
Animal VirusesLack of Focus Formation of S+L- Mink Cells by the Ecotropic
Murine Leukemia Viral Genome. AKINORI ISHIMOTO ....... 18-21Integration Sites of Adenovirus Type 12 DNA in Transformed Ham-
ster Cells and Hamster Tumor Cells. S. STABEL, W. DOER-FLER, * AND R. R. FRIIS .......... ......................... 22-40
Revertants of Adenovirus Type 12-Transformed Hamster Cell LineT637 as Tools in the Analysis of Integration Patterns. DIRKEICK, SILVIA STABEL, AND WALTER DOERFLER* ............. 41-49
Molecular Cloning and Characterization of Avian Sarcoma VirusCircular DNA Molecules. WILLIAM J. DELORBE,* PAUL A.Luciw, HOWARD M. GOODMAN, HAROLD E. VARMUS, AND J.MICHAEL BISHOP ...................................... 50-61
Synthesis and Processing of Polymerase Proteins of Wild-Type andMutant Avian Retroviruses. ROBERT N. EISENMAN,* WILLIAMS. MASON, AND MAXINE LINIAL ....... ..................... 62-78
Transcripts of the Adeno-Associated Virus Genome: Mapping of theMajor RNAs. MICHAEL R. GREEN AND ROBERT G. ROEDER* 79-92
Localization of Membrane-Associated Proteins in Vesicular Stoma-titis Virus by Use of Hydrophobic Membrane Probes and Cross-Linking Reagents. JACK J. ZAKOWSKI AND ROBERT R.WAGNER .......................... 93-102
Selective Amplification of Mouse Mammary Tumor Virus in Mam-mary Tumors of GR Mice. THOMAS G. FANNING, JOHN P.PUMA, AND ROBERT D. CARDIFF* .......................... 109-114
Amino Acid Sequence Analysis of Reverse Transcriptase Subunitsfrom Avian Myeloblastosis Virus. Terry D. Copeland, DuaneP. Grandgenett, and Stephen Oroszlan* ...... ............... 115-119
Interaction of Mycoplasma Virus Type 2 with Cellular ComponentsofAcholeplasma laidlawii Strain JAl. ABDUL J. N. AL-SHAM-MARI* AND PAUL F. SMITH ......... ........................ 120-124
Expression of the Gene for the Polyoma Small T Antigen in Esche-richia coli. ARTHUR HORWICH, ALLEN H. KooP,* AND WAL-TER ECKHART ............................................. 125-132
Rabies mRNA Translation in Xenopus laevis Oocytes. WILLIAM H.WUNNER,* PETER J. CURTIS, AND TADEUSZ J. WIKTOR ...... 133-142
New Chimeric Splice Junction in Adenovirus Type 2-Simian Virus40 Hybrid Viral mnRNA. GEORGE KHOURY,* JAMES ALWINE,NEIL GOLDMAN, PETER GRUSS, AND GILBERT JAY ..... ...... 143-151
DNA Nucleotide Sequence Heterogeneity Between the Towne andAD169 Strains of Cytomegalovirus. RANDALL F. PRITCHErr . 152-161
Expression of Endogenous Avian Myeloblastosis Virus Informationin Different Chicken Cels. J. H. CHEN ....... ............. 162-170
Synthesis, Stability, and Cleavage of Newcastle Disease Virus Gly-coproteins in the Absence of Glycosylation. T. G. MORRISON*AND D. SIMPSON ............... .......................... 171-180
Covalently Closed Circular DNAs of Murine Type C Retrovirus:Depressed Formation in Cells Treated with Cycloheximide EarlyAfter Infection. WEN K. YANG,* DEN-MEI YANG, AND JAMES0. KIGGANS, JR................... 181-188
* Asterisk refers to person to whom inquiries regarding the paper should be addressed.
CONTENTS
Fine-Structure Mapping and Functional Analysis of Temperature-Sensitive Mutants in the Gene Encoding the Herpes SimplexVirus Type 1 Immediate Early Protein VP175. RICHARD A. F.DIXON AND PRISCILLA A. SCHAFFER* ...... ................. 189-203
Oncogenic Transformation by Equine Herpesviruses. II. Coestablish-ment of Persistent Infection and Oncogenic Transformation ofHamster Embryo Cells by Equine Herpesvirus Type 1 Prepa-rations Enriched for Defective Interfering Particles. ROBIN A.ROBINSON, RALPH B. VANCE, AND DENNIS J. O'CALLAGHAN*. 204-219
Densonucleosis Virus Structural Proteins. D. C. KELLY,* N. F.MOORE, C. R. SPILLING, A. H. BARWISE, AND I. 0. WALKER .. 224-235
Anogenital Warts Contan Several Distinct Species of Human Pap-ilHlomavirus. RICHARD A. KRZYZEK,* SUSAN L. WATTS, DWIGHTL. ANDERSON, ANTHONY J. FARAS, AND FRANKLIN PASS ...... 236-244
New Endogenous Herpesvirus of Guinea Pigs: Biological and Molec-ular Characterization. FRANK J. BIA,* WILLIAM C. SUMMERS,CAROLINE K. Y. FONG, AND G. D. HSIUNG ..... ............. 245-253
Molecular Cloning of Unintegrated and a Portion of IntegratedMoloney Murine Leukemia Viral DNA in BacteriophageLambda. ANTON J. M. BERNS,* M. H. T. LAI, R. A. BOSSEL-MAN, M. A. MCKENNETT, L. T. BACHELER, H. FAN, E. C.ROBANUS MAANDAG, H. V.D. PUTTEN, AND INDER M. VERMA 254-263
Molecular Cloning of Avian Sarcoma Virus Closed Circular DNA:Structural and Biological Characterization of Three Recombi-nant Clones. PETER E. HIGHFIELD, LORI F. RAFIELD, TONAM. GILMER, AND J. THOMAS PARSONS* ...... ................ 271-279
Synthesis and Processing of Viral Glycoproteins in Two Noncondi-tional Mutants of Rous Sarcoma Virus. MAXINE LINIAL,*JAMES FENNO, W. NEAL BURNETTE, AND LARRY ROHR-SCHNEIDER ............................................... 280-290
Possible Cell Surface Receptor for Friend Murine Leukemia VirusIsolated with Viral Envelope Glycoprotein Complexes. P. J.ROBINSON,* G. HUNSMANN, J. SCHNEIDER, AND V. SCHIRR-MACHER ................................................. 291-294
Simian Virus 40-Chinese Hamster Kidney Cell Interaction. V. Co-operative Effect of 5-Iodo-2'-Deoxyuridine and Mitomycin C inthe Enhancement of Virus Replication in Infected Cells.HoRACIo G. SUALREZ,* CHRISTIAN LAVIALLE, AND ROLANDOCASSINGENA .............................................. 295-297
Bacterial VirusesCorrelation Between Genetic Map and Map of Cleavage Sites for
Sequence-Specific Endonucleases SAIl, KpnI, BgiI, and BamHIin Bacteriophage T4 Cytosine-Containing DNA. KARINCARLSON ................................................ 1-17
Suppressors of Mutations in the Bacteriophage T4 Gene Coding forBoth RNA Ligase and Tail Fiber Attachment Activities.DWIGHT H. HALL,* R. GEOFFREY SARGENT, KENNETH F. TRo-FATTER, AND DIANE L. RUSSELL .......... ................. 103-108
Probable Localization of the Bacteriophage T4 Prehead ProteinaseZymogen in the Center of the Prehead Core. ROEL VANDRIEL,* FRANZ TRAUB, AND MICHAEL K.SHOWE............. 220-223
Adsorption, Capping, and Release of a Complex Bacteriophage byMycoplasma Cells. KLAUS HABERER, JACK MANILOFF, * ANDDAVID GERLING ........................................... 264-270
CONTENTS
Volume 36 Contents for November 1980 Number2Animal Viruses
Characterization of a Unique Defective Type C Virus Associatedwith a Moloney Leukemia Virus-Induced Splenic T-Cell Lym-phoma Cell Line. IVAN HoRAK, JOHN C. LEE, Luis ENJUANES,AND JAMES N. IHLE* ............. ........................ 299-308
Separation of Cyanogen Bromide-Cleaved Peptides of the VesicularStomatitis Virus Glycoprotein and Analysis of Their Carbohy-drate Content. LAURA KINGSFORD, SUZANNE U. EMERSON, *AND J. MICHAEL KELLEY .......... ....................... 309-316
Identification of the Avian Myeloblastosis Virus Genome. I. Identi-fication of Restriction Endonuclease Fragments Associated withAcute Myeloblastic Leukemia. L. M. SOUZA AND M. A.BALUDA* ................................................ 317-324
Identification of the Avian Myeloblastosis Virus Genome. II. Restric-tion Endonuclease Analysis of DNA from A Proviral Recombi-nants and Leukemic Myeloblast Clones. L. M. SOUZA, M. J.BRISKIN, R. L. HELIYARD, AND M. A. BALUDA* ..... ......... 325-336
Unique Species of mRNA from Adenovirus Type 7 Early Region 1in Cells Transformed by Adenovirus Type 7 DNA Fragment.KoUICHI YOSHIDA AND KEI FUJINAGA* ..................... 337-352
Intracellular Forms of Simian Virus 40 Nucleoprotein Complexes.III. Study of Histone Modifications. M. COCA-PRADOS, G. Vi-DALI, AND M.-T. Hsu* .................................... 353.-360
Herpes Simplex Virus Thymidine Kinase Transcripts Are Absentfrom Both Nucleus and Cytoplasm During Infection in thePresence of Cycloheximide. WAI-CHoI LEUNG,* KENNETH Di-MOCK, JAMES R. SMILEY, AND SILVIA BACCHETrI.. 361-365
Abelson Murine Leukemia Virus Transformation-Defective Mutantswith Impaired P120-Associated Protein Kinase Activity. FREDH. REYNOLDS, JR., WIM J. M. VAN DE VEN, AND JOHN R.STEPHENSON* .. ................................. ... . 374-386
Heterogeneity of the 3' End of Minus-Strand RNA in the PoliovirusReplicative Form. OLIVER C. RICHARDS* AND ELLIE EH-RENFELD....... 387-394
Cloning of Human Papilloma Virus Genomic DNAs and Analysis ofHomologous Polynucleotide Sequences. CAROLE A. HErL-MAN,* MING-FAN LAw, MARK A. ISRAEL, AND PETER M.HOWLEY...... 395-407
Dual Evolutionary Origin for the Rat Genetic Sequences of HarveyMurine Sarcoma Virus. RONALD W. ELUS,* DEBORAH DEFEo,JEAN M. MARYAK, HowARD A. YOUNG, THOMAS Y. SHIH,ESTHER H. CHANG, DOUGLAS R. LOWY, AND EDWARD M.SCOLNICK ............................................ 408-420
Factors Which Disorganize Microtubules of Microfilaments Increasethe Frequency of Cell Transformation by Polyoma Virus.ROLAND SEIF..................................... 421-428
Synthesis and Processing of Glycoproteins gD and gC of HerpesSimplex Virus Type 1. GARY H. COHEN,* DEBORAH LONG, ANDROSELYN J. EISENBERG ................. ............. 429-439
Coronavirus Multiplication Strategy. II. Mapping the Avian Infec-tious Bronchitis Virus Intracellular RNA Species to the Ge-nome. DAVID F. STERN* AND S. IAN T. KENNEDY .......... 440-449
CONTENTS
Avian Oncovirus Mutant (SE21Q1b) Deficient in Genomic RNA:Characterization of a Deletion in the Provirus. PETER R.SHANK* AND MAXINE LINIAL .............................. 450-456
Mechanism of Inhibition ofHerpes Simplex Virus and Vaccinia VirusDNA Polymerases by Aphidicolin, a Highly Specific Inhibitor ofDNA Replication in Eucaryotes. GUIDO PEDRALI-NOY ANDSILVIO SPADARI*.457-464
Virion Nucleic Acid of Ebola Virus. RUSSELL L. REGNERY,* KARLM. JOHNSON, AND MICHAEL P. KILEY.465-469
Interaction of Influenza M Protein with Viral Lipid and Phosphati-dylcholine Vesicles. ANASTASIA GREGORIADES.470-479
Arrangement of the Genome of the Human Papovavirus RFVirus. ALAN PATER,* MARY M. PATER, AND GIAMPIERO DIMAYORCA.480-487
Identification and Initial Characterization of a New Low-Molecular-Weight Virus-Encoded T Antigen in a Line of Simian Virus 40-Transformed Cells. GREGORY J. SPANGLER, JAMES D. GRIF-FIN, HARVEY RUBIN, AND DAVID M. LIVINGSTON*.488-498
Close Similarity Between Endogenous Ecotropic Virus of Mus mus-culus molossinus and AKR Virus. SISIR K. CHATTOPADHYAY, *MARILYN R. LANDER, AND WALLACE P. ROWE.499-505
Epstein-Barr Virus RNA. V. Viral RNA in a Restringently Infected,Growth-Transformed Cell Line. WALTER KING, ANN L.THOMAS-POWELL, NANCY RAAB-TRAUB, MARY HAWKE, ANDELLIOTT KIEFF*.506-518
Characterization of Tau Antigens Isolated from Uninfected andSimian Virus 40-Infected Monkey Cells and Papovavirus-Trans-formed Cels. DANIEL T. SIMMONS.519-525
BALB/c Myeloma Retroviruses: Peptide Mapping and Immunolog-ical Analysis of the ppl2 Structural Protein. DALE R. SPRIGGSAND ROBERT G. KRUEGER ................................ 533-540
BALB/c Myeloma Retroviruses Have Mink Cell Focus-InducingActivity. DALE R. SPRIGGS, MARY A. DIEBOLD, AND ROBERTG. KRUEGER*.541-546
Abelson Murine Leukemia Virus-Induced Tumors Elicit AntibodiesAgainst a Host Cell Protein, P50. VARDA ROTTER, OWEN N.WITTE, ROBERT COFFMAN, AND DAVID BALTIMORE*.547-555
Small Reovirus-Specific Particle with Polycytidylate-DependentRNA Polymerase Activity. PETER J. GOMATOS,* NICHOLAS M.STAMATOS, AND NURUL H. SARKAR.556-565
A Cloned Polyoma DNA Fragment Representing the 5' Half of theEarly Gene Region Is Oncogenic. KAMAL CHOWDHURY,* SU-SAN E. LIGHT, CLAUDE F. GARON, YOSHIAKI ITO, AND MARK A.ISRAEL.566-574
Molecular Cloning of the Avian Erythroblastosis Virus Genome andRecovery of Oncogenic Virus by Transfection of ChickenCells. BJORN VENNSTROM,* LOIS FANSHIER, CARLO MOSCO-VICI, AND J. MICHAEL BISHOP.575-585
Incorporation of Influenza Virus M-Protein into Liposomes. D. J.BUCHER,* I. G. KHARITONENKOV, J. A. ZAKOMIRDIN, V. V.GRIGORIEV, S. M. KLIMENKO, AND J. F. DAVIS.586-590
Generation of Nondefective Rous Sarcoma Virus by AsymmetricRecombination Between Deletion Mutants. G. S. MARTIN,*W.-H. LEE, AND P. H. DUESBERG .......................... 591-594
CONTENTS
Leakage of Nuclear Transcripts Late in Simian Virus 40-InfectedCV1 Cells: Quantitation of Spliced and Unspliced Late 19SRNAs. Luis P. VILLARREAL* AND SUSAN JOVANOVICH 595-600
Dinucleotide Sequences at the 5' Ends of Vaccinia Virus mRNA'sSynthesized In Vitro. JERRY M. KEITH, ALAN GERSHOWITZ,AND BERNARD Moss* ..................................... 601-605
Abrogation of Radiation Leukemia Virus-Induced Lymphomagenesisby Antisera to Thymotropic but Not to Ecotropic or Dual-Tropic Viruses. MARTIN HAAs* AND JAN JONGSTRA . 606-610
Construction of a Specific Amber Codon in the Simian Virus 40 T-Antigen Gene by Site-Directed Mutagenesis. DAN R. RAWLINSAND NICHOLAS MUZYCZA* ............................ 611-616
Phosphorylation of the Nonstructural Proteins Encoded by ThreeAvian Acute Leukemia Viruses and by Avian Fujinami SarcomaVirus. KLAUS BISTER, WEN-HwA LEE, AND PETER H.DUESBERG* ............................................... 617-621
Viruses Isolated from Cells Persistently Infected with VesicularStomatitis Virus Show Altered Interactions with Defective In-terfering Particles. FRANK M. HORODYSKI AND JOHN J.HOLLAND* ............................................... 627-631
Bacterial VirusesSuperinfection Exclusion by Heteroimmune Corynebacteriophages.
N. B. GROMAN* AND M. RABIN ....................... 526-532New Deletion Mutant of Bacteriophage T5. MARC RHOADES,*
JOANNA SCHWARTZ, AND JEFFREY M. WAHL ..... ........... 622-626
Plant VirusesExpression of Bottom Component RNA of Cowpea Mosaic Virus in
Cowpea Protoplasts. GEERTJE REZELMAN, ROB GOLDBACH,*AND ALBERT VAN KAMMEN ......... ...................... 366-373
Volume 36 Contents for December 1980 Number 3
Animal VirusesMappings of Adenovirus 12 mRNA's Transcribed from the Trans-
forming Region. YUKIHARU SAWADA AND KEI FUJINAGA* ... 639-651Viral Hemorrhagic Septicemia of Rainbow Trout: Selection of a
Thermoresistant Virus Variant and Comparison of PolypeptideSynthesis with the Wild-Type Virus Strain. P. DE KINKELIN,*MONIQUE BEARZOrrI-LE BERRE, AND JACQUELINE BERNARD 652-658
Comparison of the Nucleotide Sequence at the 5' End of RNAs fromNine Aphthoviruses, Including Representatives of the SevenSerotypes. TIMOTHY J. R. HARRIS.659-664
gA and gB Glycoproteins of Herpes Simplex Virus Type 1: TwoForms of a Single Polypeptide. R. EBERLE AND RICHARD J.COURTNEY* .............................................. 665-675
Avian Erythroblastosis Virus Produces Two mRNA's. STEVEN M.ANDERSON,* WILLIAM S. HAYWARD, BENJAMIN G. NEEL, ANDHIDESABURO HANAFUSA .......... ........................ 676-683
Integration, Expression, and Infectivity of Exogenously AcquiredProviruses of Rous-Associated Virus-0. NANCY A. JENKINSAND GEOFFREY M. COOPER* .............................. 684-691
CONTENTS
Reverse Transcriptase as the Major Determinant for Selective Pack-aging of tRNA's into Avian Sarcoma Virus Particles. GORDONG. PETERS* AND JAMES Hu ......... ...................... 692-700
Simian Virus 40-Associated Small RNA: Mapping on the SimianVirus 40 Genome and Characterization of Its Synthesis. JAMESC. ALWINE* AND GEORGE KHOURY ....... .................. 701-708
Physical Map of Infectious Baboon Type C Viral DNA and Sites ofIntegration in Infected Cells. NARAYANA BATTULA* ANDGEORGE J. TODARO ............. .......................... 709-718
Translational Control of Protein Synthesis After Infection by Vesic-ular Stomatitis Virus. HARVEY F. LODISH* AND MARYPORTER ................................................. 719-733
Characterization of Endogenous and Exogenous Mouse MammaryTumor Virus Proviral DNA with Site-Specific MolecularClones. BERND GRONER,* ELENA BUETrI, HEIDI DIGGEL-MANN, AND NANCY E. HYNES ........ ...................... 734-745
Properties of Cells Carrying the Herpes Simplex Virus Type 2 Thy-midine Kinase Gene: Mechanisms of Reversion to a ThymidineKinase-Negative Phenotype. K. F. BASTOW, G. DARBY, P.WILDY, AND A. C. MINSON* ......... ...................... 746-755
RNA Synthesis of Vesicular Stomatitis Virus. X. Transcription andReplication by Defective Interfering Particles. DONALD D.RAO AND ALICE S. HUANG* ......... ...................... 756-765
Abelson Murine Leukemia Virus Mutants Deficient in Kinase Activ-ity and Lymphoid Cell Transformation. NAOMI E. ROSEN-BERG,* DANIEL R. CLARK, AND OWEN N. WITrE ..... ....... 766-774
Intracellular Distribution of Sindbis Virus Membrane Proteins inBHK-21 Cells Infected with Wild-Type Virus and Maturation-Defective Mutants. CHRISTINE ERWIN AND DENNIS T.BROWN*.... 775-786
Structural Relationships Between the Surface Antigens of GroundSquirrel Hepatitis Virus and Human Hepatitis B Virus.WOLFRAM H. GERLICH, MARK A. FEITELSON, PATRICIA L. MAR-ION, AND WILLIAM S. ROBINSON* ....... ................... 787-795
Replicative RNA Synthesis and Nucleocapsid Assembly in VesicularStomatitis Virus-Infected Permeable CelLs. JON H. CONDRA*AND ROBERT A. LAZZARINI ......... ....................... 796-804
Association of pp6Osrc and src Protein Kinase Activity with thePlasma Membrane of Nonpermissive and Pernissive Avian Sar-coma Virus-Infected Cells. R. A. KJRZYZEK, R. L. MITCHELL,A. F. LAU, AND A. J. FARAS* ........ ...................... 805-815
Analysis of Herpes Simplex Virus Nucleoprotein Complexes Ex-tracted from Infected Cells. PIER F. PIGNATTI* AND ENZOCASSAI .................................................. 816-828
Virus of Pekin Ducks with Structural and Biological Relatedness toHuman Hepatitis B Virus. WILLIAM S. MASON,* GEETA SEAL,AND JESSE SUMMERS ........... .......................... 829-836
Nucleic Acids of Respiratory Syncytial Virus. DENNIS M. LAM-BERT,* MARCEL W. PONS, GUSTAVE N. MBUY, AND KAROLINEDORSCH-HASLER ................ ......................... 837-846
Defective Interfering Influenza Viruses and Host CelLs: Establish-ment and Maintenance of Persistent Influenza Virus Infectionin MDBK and HeLa Cells. BARUN K. DE AND DEBI P.NAYAK...*.............................................. 847-859
CONTENTS
Regulation of Integrated Adenovirus Sequences During AdenovirusInfection of Transformed Cells. DAVID J. SPECTOR, DONALDN. HALBERT, AND HESCHEL J. RASKAS* ........... ......... 860-871
Structure of and Alterations to Defective Murine Sarcoma VirusParticles Lacking Envelope Proteins and Core PolyproteinCleavage. ANTHONY DEMSEY,* FULMER COLLINS, AND DOUG-LAS KAWRKA.......... 872-877
Cloned Human Polyomavirus JC DNA Can Transform Human Am-nion Cells. PETER M. HOWLEY,* FRANCOISE RENTIER-DEL-RUE, CAROLE A. HEILMAN, MING-FAN LAW, KAMAL CHOW-DHURY, MARK A. ISRAEL, AND KENNETH K. TAKEMOTO ...... 878-882
Envelope Assembly Mutant of Rous Sarcoma Virus. KATHELYN S.-STEIMER* AND DAVID BOETTIGER ......................... 883-888
Partial Phosphorylation In Vivo of the Avian Retrovirus pp32DNA Endonuclease. RON D. SCHIFF AND DUANE P.GRANDGENETT* ................... .... 889-893
Subunit Structure of the Reovirus Spike. S. J. RALPH, J. D.HARVEY, AND A. R. BELLAMY ............................. 894-896
Bacternil VirusesEvidence for Heterogeneity in Populations of T5 Bacteriophage. II.
Some Particles Are Unable to Inject Their Second-Step-Trans-fer DNA. CHRISTIAN HULEN,* BERNARD LABEDAN, AND JEANLEGAULT-DEMARE.633-638