Jeffrey R. Dugas, MD Birmingham, Al...Exclusively single -bundle Autograft PTG greater than 75%...

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Jeffrey R. Dugas, MD Birmingham, Al Mark Clatworthy Tim Roberts Middlemore Hospital Auckland New Zealand

Transcript of Jeffrey R. Dugas, MD Birmingham, Al...Exclusively single -bundle Autograft PTG greater than 75%...

Jeffrey R. Dugas, MD Birmingham, Al

Mark Clatworthy Tim Roberts

Middlemore Hospital Auckland

New Zealand

No disclosures related to the subject matter of this presentation.

Significant changes in the way ACL surgery is performed Double Bundle Various Femoral Tunnel Drilling techniques Addition of various biologic “enhancements”

Basic science supports the fact that the ACL is comprised of two “bundles” of fibers which function in conert.

Idea of recreating two bundles certainly seems reasonable given the native anatomy

Clinically challenging technique to get two grafts at the native origin of the ACL

Clinical results have (to date) failed to show superiority or reliable equivalence to large scale clinical studies of single bundle ACL reconstruction.

Many early adopters of this technique have returned to single bundle ACL reconstruction.

Transtibial drilling was the most common technique until 5-10 years ago. Evidence that transtibial drilling led to

unacceptable position of the femoral tunnel Possible cause of early failure of ACL graft due

to vertical orientation. Medial Portal Drilling espoused as the solution

to more accurately recreate the normal anatomic origin of the ACL.

Miller et al and others 2010-2014 “It is borderline malpractice to drill through the

tibial tunnel.”

Exclusively single-bundle Autograft PTG greater than 75% Autogranft HS greater than 20% Allograft PTG less than 5%

Nearly all femoral tunnels drilled TT (>95%) ? Are we doing this wrong? If so, are we not seeing our own failures, or are we doing

something different which allows us to get lower on the wall Are we settling for a lesser graft position without knowing it?

Asked outgoing fellows how our technique is different from what they experienced in residency/experience

Bigger Notchplasty Use of a fixed angle tibial guide (45 degrees) Free-hand reaming of femoral tunnel

No drill guides for femoral tunnel placement

“you get pretty low” Compliment?

1. To determine if there was any benefit to notchplasty in placing the femoral tunnel transtibially

2. To determine the amount of fill of the native ACL origin using the two techniques before and after notchplasty.

3. To measure the tunnel length using the two techniques to better understand the risk of posterior cortical compromise

70% coverage of the native ACL origin

88% coverage of the native ACL origin

Post-notchplasty transtibial drilled femoral tunnels yielded 68.3% coverage of the native origin of the ACL.

Post-notchplasty MP drilled femoral tunnel yielded 67.6% coverage of the native origin of the ACL.

No Notchplasty yielded less than 30% coverage in the MP group and less than 10% coverage in the TT group

Single surgeon clinical experience with clinical follow-up

Prospective study - Private practice

August 2000 - May 2009 – Hamstring transtibial ACLR

Transtibial technique – . Medial tibial incision - oblique shallow tibial tunnel. High AM femoral position still within the footprint.

May 2009 – May 2013 – Hamstring Transportal ACLR

Transportal ACLR technique - 30% distal (forward) off the back wall and lower (posterior), More anterior tibial tunnel – centromedial

All patients had Endobutton/Retrobutton for femoral fixation and Intrafix/GraftBolt for tibial fixation

Failure - return to surgeon for revision, clinical failure with MRI and known revision by other surgeon - Will underestimate failure rate

TransTibial TransPortal

52 failures in 1016 TT ACLR followed for 6-15 years mean 8.9 years - 5.1% failure rate

31 failures in 464 TP ACLR followed for 2-6 years mean 4 years - 6.7% failure rate

13 failures in 419 TT ACLR followed for 2-6 years 3.1% failure rate TP technique 2.2 X higher failure rate

Hazard Ratio – more sophisticated evaluation that allows for variation in follow up The TP technique has a 2.4 X higher hazard ratio than the TT technique p=<0.001

Trans Tibial Trans Portal Significance

Age 32.1 32.3 N.S

Sex F/M 35/65 36/64 N.S

Graft Size 7.8 7.7 0.02

Time to Surgery 15.5 24.5 0.001

Medial Meniscal % 87.4% 91.3% 0.002

Lateral Meniscal % 93.6% 95.3% 0.028

Medial Meniscal Repair 24.1% 16.4% <0.001

Lateral Meniscal Repair 7.2% 5% N.S

The TP technique has a 2 .3X higher hazard ratio than the TT technique when all factors are taken into account p=0.001

TP 0.14 failures / 100 graft years 3.5 x higher failure TT 0.04 failures / 100 graft years p=<0.001

97%

91%

61% of TP ACLR’s failed < 1 year post surgery

27% of TT ACLR’s failed < 1 year post surgery p=<0.0001

Mean time to failure within 6 years TP 12.2 months, TT 29.2 months p =0.02

Changed in May 2013 to AM femoral tunnel, continued with

transportal, maintained centromedial tibia. Increased BPB ACLR’s

Last two years TP AM femur - 178 hamstring patients 1 failure 0.5% ruptured within two years

BPB AM femoral footprint – 30 patients No failures

First 2 years TP central femoral footprint 238 patients. 9 graft failures – 3.8% ruptured within 2 years

First 2 years TT AM femoral footprint, posterior tibial tunnel 171 patients – 3 graft failures - 1.8% ruptured within 2 years

The TP technique has a 2.3 x higher hazard ratio for failure than the TT technique with a multi-variate analysis p=0.002

With a 6 year follow up TP ACLR has 2.2x higher failure rate than TT ACLR

The TP technique has a 3.5 X higher failure rate when utilising failures / 100 graft years

TP ACLR’s failure have a higher earlier failure rate - 61% vs 27% < 1 year post surgery p=0.001

Moving the femoral tunnel back to a high AM position has resulted in a 7.2X lower failure rate

Placement of the ACL graft in an more central footprint position results in a higher failure rate and an earlier failure than placement in a high AM position

Anatomy Re-evaluation – Direct vs Indirect Fibres

Histological Evaluation of Footprints Sectional Fibre ACL Biomechanical Analysis

Isometricity Evaluation

Robert Smigielski Dissection of 111 fresh cadaveric knees Flat insertion; Not 2 bundles The ACL arises from the lateral intercondylar

ridge

Presenter
Presentation Notes
So we went ahead and revisited the anatomy. What became apparent from attending ACL-focused meeting, including the ACL study group, was that a number of groups had done so in the past year. One investigator deserves mention. Robert Smigielski, Orthopedic Surgeon in Warsaw, Poland.

Arthroscopy 2010 Direct insertion of ACL origin into ridge

Indirect fibres fan out to fill the footprint

KSSTA 2014 Direct dense fibres insert into lateral

intercondylar ridge Fan like extension posterior to the ridge

Presenter
Presentation Notes
Central area resistd 80-90% of anterior force during anterior stress testing Proximal region (GH) resisted 70-80% of the anterior force during anterior stress testing

Lachman Anterior Draw

HA

HC

HP LA LC

LP

HA = High AM

HC = High Center

HP = High PL

LA = Low AM

LC = Low Center

LP = Low PL

0.00

2.00

4.00

6.00

8.00

10.00

12.00

14.00

High AM High Center High PL Low AM Low Center Low PL

Mea

n C

hang

e in

AC

L Le

ngth

(mm

)

Femoral Graft Location

3.6 mm

10.8 mm

HA

HC

HP LA LC

LP

HA = High AM

HC = High Center

HP = High PL

LA = Low AM

LC = Low Center

LP = Low PL

More forward (distal) and lower (posterior) femoral graft placement does not replicate the direct insertion of the ACL which is the lateral intercondylar ridge This results in an anisometric graft with higher strain through the graft

This is the likely explanation for the increased failure rate of “Central Footprint ACLR”

80% of the functional ACL fibers arise from the AM bundle. The AM bundle is more isometric

Worse biomechanically to be lower on the wall (more posterior) than to be higher on the wall (more anterior).

“The biggest mistake I made in my entire career in sports medicine was to try to get lower on the wall drilling my femoral tunnels.” Dr. Russell Warren

Basic science studies that give us valuable information about native anatomy may not always lead us in the direction of clinical success. Time zero surgical appearance is not always

indicative of final clinical outcome

Must always strive first for clinical success

Regardless of how the femoral tunnel is drilled in ACL surgery, the key is to get the graft into the most normal position possible to allow for normal biomechanics when the graft is healed and mature.

Lower doesn’t mean better.