James O. Hill, Ph.D. : Obesity, The Big Picture

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    Obesity: The Big Picture

    James O. Hill, Ph.D.Anschutz Professor

    University of Colorado

    Anschutz Health and Wellness Center

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    Obesity Issues 2014

    Where are we today? Who is getting fat?

    The biology of obesity

    Transformational weight loss

    Food vs Physical Activity

    Metabolic Flexibility and Obesity Evaluating Research

    Physical activity and brain function

    The new science of sedentarianism

    Strategic movement through the workday

    Small steps and nudges Impact of food taxes

    Role of the Food and Beverage Industry

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    Trends in overweight, obesity and extreme obesity, ages 20-74 years

    0%

    5%

    10%

    15%

    20%

    25%

    30%

    35%

    40%

    1960-62 1971-74 1976-80 1988-94 1999-00 2001-02 2003-04 2005-06 2007-08 2009-10

    Overweight

    Obese

    Note: Age-adjusted by the direct method to the year 2000 US Bureau of the Census using age groups 20-39, 40-59 and 60-74 years.Pregnant females excluded. Overweight defined as 24,=BMI; obesity defines as BMI>=30; Extreme obesity defines as BMI>=40.

    Extremely Obese

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    0%

    5%

    10%

    15%

    20%

    25%

    1963-65 1971-74 1976-80 1988-94 1999-00 2001-02 2003-04 2005-06 2007-08 2009-10 2011-2012

    Note: Overweight is defined as BMI>=gender and weight-specific 95th percentile from the 2000 CDC Growth Charts. Source:National Health Examination Surveys II (ages 6-11) and III (ages 12-17), National Examination Surveys, I, II, III and 1999-204, NCHS,CDC.

    Age 12-19

    Age 6-11

    Age 2-5

    Trends in child and adolescent overweight

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    Causes of Obesity

    Energy intake

    Energy expenditureEnergy expenditure

    Energy intake

    WEIGHT GAIN

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    Who is becoming obese?

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    Contributors to Obesity

    Biology Behavior

    Environment

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    Biology: The Energy Balance System

    EnergyIntake

    EnergyExpenditure

    EnergyStores

    Active

    Regulation/Integration

    InheritedFactors EnvironmentalFactors

    Efficiency

    Adaptive thermogenesis

    Food preferences

    Food environment

    Physical activity

    environment

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    Socioecological Models

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    Decrease

    Energy

    Intake

    Body weight increases

    Body weight does not change

    Body weight decreases

    Usual physical activity

    Metabolic RateFood Intake

    What happens to body weight when food intake isdecreased?

    Wh t h t b d i ht h h i l ti it i

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    Increase

    Physical

    Activity

    Body weight increases

    Body weight does not change

    Body weight decreases

    Usual physical activity

    Metabolic RateFood Intake

    What happens to body weight when physical activity isincreased?

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    Addressing the Environment

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    Biology: Influenced by Environment andBehavior

    Drive to eateat whenever food is available Like sugar, fat, salt Happy being sedentarylittle need for physical activity

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    Biology Desire to Eat Pref for sweet/fat No Drive to be active

    FoodAvailableGood tasting

    Energy dense

    Inexpensive

    Large portions

    Physical ActivityLittle need for physical activity in daily living

    Attractiveness of sedentary Entertainment

    Car for Transportation

    Economics

    Consume More

    More for lessGreater Productivity

    DecreasedEnergyExpenditure

    IncreasedEnergy

    Intake

    ObesitySocioculturalForces

    Challenges in reducing obesity

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    How do we begin to study the

    problem?

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    Foreyt, John, and Ken Goodrick. "The ultimate triumph of obesity."The Lancet346.8968 (1995): 134-135.

    Last American becomes obese in 2230

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    Promoting Cognitive Skills

    Making conscious efforts to overcomebiological and environment influencestoward obesity

    Biology

    Environment

    Behavior

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    Hill 5-Point Plan to Reduce Obesity

    Prioritize prevention over treatment Increase physical activity of the population

    Promote Smart Eatingusing small changes Use small changes to change environment Teach Cognitive Skills

    Big Challenge: We have to give people a reason to want to change

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    Energy Gap forprevention of weightgain

    Energy Gap formaintenance forweight loss

    BodyWeight

    Time

    What will it take to reduce obesity? The energy gap

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    Energy

    Gap

    -10% (10 kg) = 190-200 kcal/day

    -15% (15kg) = 280-300 kcal/day

    Energy

    Gap

    Obesity

    How much behavior change is needed for

    successful weight loss maintenance?

    Example for 100 kg person

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    Body

    WeightEnergy

    Gap

    Energy

    Gap

    EnergyGap

    Healthy Weight

    Overweight

    Obese

    Energy Gap for Prevention of Weight Gain

    (

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    TRANSFORMATION

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    When it comes to weight, which is more important:Food vs Physical Activity

    Eat a bacon cheeseburger and consume 720 kcal in 5 min Takes 2.6 hours of walking at moderate intensity to burn it off

    I worked 8 hours today to make $500 I spent $500 in 15 min on concert tickets

    When it comes to net worth, which is more important:Income vs Spending

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    Body Weight

    EnergyIntake

    Our biology works best at high

    Physical Activity

    Threshold forOptimal Weight

    Regulation

    UnregulatedZone

    Regulated Zone

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    Energy

    Intake

    Energy Expenditure

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    Smart Eating

    Portion Size Energy Density Liquid Calories

    Healthy Defaults

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    Messages

    Eat Less and Move More Eat Smarter and Move More

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    The birth of small changes

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    Source: D.M. Bravata et.al., JAMA 298: 2296-2304, 2007

    Pedometers To Increase Activity

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    A better approach: Healthy Defaults

    Disney parks Kids meals come with low fat milk and fruit

    Starbucks Drinks made with low fat milk

    Portion sizes/energy density Would anyone notice a 5% reduction?

    School drop offs Buses and cars drop kids off 500 steps from

    school

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    0

    100

    200

    300

    400

    500

    600

    700

    Calories

    7-Eleven Soft Drinks

    Super Big

    Gulp

    Gulp Big Gulp Double

    Gulp

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    333 kcal

    590 kcal

    The Cheeseburger

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    Why Change Anything?

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    Program partners: Primary funder:

    Developing Skills

    PI: James O. Hill, Ph.D.

    http://www.ucdenver.edu/academics/colleges/medicalschool/centers/HealthandWellnessCenter/Pages/Home.aspx
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    The 5thGear Card

    10% Discountat King Sooperson KingSoopers brandfoods.

    Show your cardfor discountsand to earnpoints at other

    partners Redeem yourpoints for prizesat www.5thGearKids.org

    http://www.5thgearkids.org/http://www.5thgearkids.org/
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    Sustaining Behavior Change

    RegulateBehaviorControl/LimitChoices

    Educate toallow people to

    make betterchoices

    FOOD

    TaxesPricingExposure

    Zoning RestrictionsMenu LabelingPortion ControlRestrictions on bad foodsRegulations for school foods

    PHYSICAL ACTIVITY

    Increase active transportReduce sedentary behaviorImprove physical activity programsMandate physical activity inschools

    Where is the middle ground?

    Public-Private Partnerships

    We will need policy but what and when?

    Parents must take thelead in reducingchildrens TV watching

    and provide alternatives

    Are children prey for fastfood companies?

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    Biology Desire to Eat Pref for sweet/fat No Drive to be active

    FoodAvailableGood tasting

    Energy dense

    Inexpensive

    Large portions

    Physical ActivityLittle need for physical activity in daily living

    Attractiveness of sedentary Entertainment

    Car for Transportation

    Economics

    Consume More

    More for lessGreater Productivity

    DecreasedEnergyExpenditure

    IncreasedEnergyIntake

    ObesitySocioculturalForces

    Reason to push back

    Different Value Equation

    Social Environment of Wellness

    Make betterchoices

    Challenges in reducing obesity

    Energy BalanceSkills

    Health & Wellness Center

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    Health & Wellness Center

    Integration andinteraction

    Health &Wellness

    Clinical

    Education

    Research

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    Addressing a Complex Issue

    PrivateSectorPartnershipsCommunity

    Engagement

    Create new thinking spacefor creating solutions

    Develop and TestPotential Solutions Implement

    Science-Based,Scalable Programsand Initiatives

    Model schoolsModel worksites

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    HEALTH VS WELLNESS

    PreventionAccumulating Wellness

    Pulmonary GIDermatologicalOrthopedic GenitourinaryPsychological Asthma

    DiabetesCardiovascular DiseaseCognitive ImpairmentRenal DiseaseCancer

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    CU Wellness Score

    DietQuality

    Quality ofLife Sleep

    Stress

    MetabolicFitness

    PhysicalFitness

    Your WellnessScore:62 (out of 100)

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    Thank You!