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Journal of Porphyrins and PhthalocyaninesJ. Porphyrins Phthalocyanines 2020; 24: 1243–1401

In order to further highlight their prestigious awards and maintain their legacy, the 2018 and 2020 Lifetime Achievement and SPP/JPP Young Investigator Award (attributed by the Society of Porphyrins and Phthalocyanines) winners’ contributions are gathered together in this first award issue, which will aim to become a regular installment throughout future award presentations at the occasion of the International Conference on Porphyrins and Phthalocyanines. Congratulations once again to all of the winners, past and present.

About the Cover

2018 Lifetime Achievement Award Paper

2018 SPP/JPP Young Investigator Award Papers

pp. 1243–1257Supramolecular phthalocyanine assemblies — a Linstead Career Award paperRoeland J.M. Nolte*Phthalocyanines can be self-assembled in solution and on surfaces to give supramolecular materials that can be applied as sensors, as photo-electronic materials, and as alignment layers for the fabrication of liquid-crystalline displays.

pp. 1258–1271Development of synthetic protocols for porphyrins and their analogs based on distorted structures — a SPP/JPP Young Investigator Award paperSatoru Hiroto*This manuscript summarizes the work concerned in a 2018 SPP/JPP Young Investigator Award. The synthetic protocol leading to distorted porphyrins and the analysis of the effect of the distorted conformations on their properties is described.The work contains three sections: Creation of novel porphyrin derivatives using planarization of distorted precursors; Oxidative fusion of porphyrins and related analogs; and Chemistry of π-extended and distorted pyrroles.

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J. Porphyrins Phthalocyanines 2020; 24: 1243–1401

pp. 1320–1360Photodynamic therapy, priming and optical imaging: Potential co-conspirators in treatment design and optimization — a Thomas Dougherty Award for Excellence in PDT PaperPushpamali De Silva, Mohammad A. Saad, Hanna C. Thomsen, Shazia Bano, Shoaib Ashraf and Tayyaba Hasan*The process of photochemical activation of certain molecules (photosensitizers), referred to as photodynamic therapy, is a multifaceted approach that can be exploited for therapy and imaging in various organisms. More recently it has emerged as a priming tool to enhance the therapeutic efficacy of other treatment modalities including chemotherapy and immunotherapy. This review provides a perspective of the current status of PDT, with a glimpse into what it might offer in the future, specifically in the context of parallel advances in imaging technologies and nanomedicine.

pp. 1278–1299The relationship between photophysical properties and aromaticity/antiaromaticity of various expanded porphyrins — a Hans Fischer Career Award paperJinseok Kim, Gakhyun Kim and Dongho Kim*Aromaticity is one of the crucial concepts for predicting the molecular properties and rea-ctivity of cyclic π-conjugated systems. This review focuses on the evaluation of aromaticity via spectroscopic methods in various expanded porphyrin systems. The relationship between the photophysical properties and distinct aromatic characteristics in Hückel aromatic compounds was revealed through notable spectroscopic features exhibited by aromatic expanded porphyrins. Furthermore, modulating the molecular conformation and chemical environment enabled us to distinguish unique Möbius aromatic molecules successfully.

pp. 1272–1277Thinking outside the macrocycle: Potential biomedical roles for nanostructured porphyrins and phthalocyanines — a SPP/JPP Young Investigator Award paperJonathan F. Lovell*In this 2018 SPP/JPP Young Investigator Award perspective, select emerging applications for supramolecular porphyrin and phthalocyanines in the biomedical sciences are discussed. The topics covered are restricted to applications of porphyrin polymer hydrogels, porphysomes and surfactant-stripped micelles.

2020 Lifetime Achievement Award Papers

pp. 1300–1319A career in photophysicochemical and electrochemical properties of phthalocyanine — a Linstead Career Award paperTebello Nyokong*The author describes decades of her research on the chemistry of phthalo-cyanines and their applications in healthcare (photodynamic inactivation of bacteria, and treatment of cancer), pollution control (photodegradation of pollutants), renewable energy (dye-sensitized solar cells), safety (nonlinear optics) and on sensors when alone and in combination with nanomaterials.

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J. Porphyrins Phthalocyanines 2020; 24: 1243–1401

pp. 1387–1401Combined pH-responsive chemotherapy and glutathione triggered photosensitization to overcome drug-resistant hepatocellular carcinoma — a SPP/JPP Young Investi-gator Award paperDi Gao and Pui-Chi Lo*We have successfully prepared polymeric micelles conjugating with doxorubicin (DOX) and zinc(II) phthalocyanine (ZnPc) through a pH-responsive hydrazone linker and a glutathione-responsive disulfide linker. The DOX and ZnPc could be released under an acidic condition and reducing environment, inducing chemotherapeutic and photodynamic effect, respectively. The utilization of polymeric micelles can significantly enhance the cellular uptake and cytotoxicity of DOX against DOX-resistant R-HepG2 cells when compared with free DOX. Moreover, PDT can act as adjuvant therapeutic modality and combine with chemotherapy to further improve the therapeutic efficacy.

pp. 1361–1371First-row transition metal porphyrins for electrocatalytic hydrogen evolution — a SPP/JPP Young Investigator Award paperHaitao Lei, Yabo Wang, Qingxin Zhang and Rui Cao*A series of first-row transition metal complexes of tetrakis(pentafluorophenyl)porphyrin (1), denoted as 1-M (M = Mn, Fe, Co, Ni, Cu, and Zn), were synthesized and examined as electrocatalysts for the hydrogen evolution reaction.

2020 SPP/JPP Young Investigator Award Papers

pp. 1372–1386Microviscosity and temperature sensors: The twists and turns of the photophysics of conjugated porphyrin dimers — a SPP/JPP Young Investigator Award paperAurimas Vyšniauskas and Marina K. Kuimova*Conjugated porphyrin dimers are a class of exciting compounds known for their far-red absorption and emission, high yields of singlet oxygen sensitization and biocompatibility. Recently it has emerged that porphyrin dimers can also be used for sensing microviscosity and temperature. In this review, we describe the sensing mechanism and demonstrate multiple applications of conjugated porphyrin dimer for sensing microviscosity and temperature in samples ranging from solvents to polymers to live cells.