IVF and Embryology Techniques To Maximize Your Chances

UK/IRE Seminar June 2019

Jerald Goldstein, M.D.Medical Director

Fertility Specialists of Texas

IVF and Embryology Techniques To Maximize Your Chances

▪ Medical Testing

▪ Semen Analysis

▪ PGT-A Testing

▪ Single vs Double Embryo Testing


Frisco Dallas Grapevine

▪ Founded in 2005 by Dr. Jerald Goldstein

▪ 4 Office Locations▪ 5 Physicians


Intended ParentsSemen Analysis

Semen Freeze

FDA Panel

Genetic Testing

Egg Donor

Detailed Medical history

Physical Exam

Blood test and FDA panel

Pelvic Ultrasound

Surrogacy AgencyMedical and Obstetrical History

Physical exam

Prepregnancy blood panel

Pelvic Ultrasound


▪ Anti-Mullerian hormone (AMH)

level

▪ Transvaginal ultrasound for

ovarian volume and antral follicle

count

▪ Day 3 FSH and Estradiol level


▪ Chromosome Test (embryo)

▪ Gene mutation screening

(Cystic Fibrosis, Fragile X)


▪ Meet and Discuss the

process of making

embryos

▪ Semen analysis and

Cryopreserve sperm

(three days of abstinence)

▪ FDA Questionnaire

▪ Physical Exam


▪ Volume: > 2 mL

▪ Concentration: > 15,000,000 per mL

▪ Motility: > 40%

▪ Normal morphology: > 4% normal


Pros:

▪ Identify chromosomally

normal embryos

▪ Saves time and money in the

long run

▪ Reduces miscarriages

▪ Piece of mind

Cons:

▪ No improvement in pregnancy rates for

young women

▪ Possible damage to embryo

▪ Requires embryo freeze and thaw

▪ Cost


Oocyte recovery Fertilization Day Five embryos


Pros:

▪ Identify chromosomally

normal embryos

▪ Saves time and money in the

long run

▪ Reduces miscarriages

▪ Piece of mind

Cons:

▪ No improvement in pregnancy rates for

young women

▪ Possible damage to embryo

▪ Requires embryo freeze and thaw

▪ Cost


Oocyte recovery Fertilization Day Five embryos


1 vs. 2


50%

55%

60%

65%

70%

75%

80%

85%

Single ET DonorEmbryo

Double ETDonor Embryo%

Cli

nic

al

Pre

gn

an

cy R

ate

Success RatesSingle Vs. Double ET

FST 2010-2019


Where the waiting ends and families begin.

IVF and Embryology Techniques To Maximize Your Chances

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