Issues in Inorganic Synthesis. Ligand synthesis in NaOH pH ~11 MeOH 20 h or so Solvent : ethylene...
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Transcript of Issues in Inorganic Synthesis. Ligand synthesis in NaOH pH ~11 MeOH 20 h or so Solvent : ethylene...
![Page 1: Issues in Inorganic Synthesis. Ligand synthesis in NaOH pH ~11 MeOH 20 h or so Solvent : ethylene glycol.](https://reader035.fdocuments.us/reader035/viewer/2022062407/56649e165503460f94b008b3/html5/thumbnails/1.jpg)
Issues in Inorganic Synthesis
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Ligand synthesis
in NaOH pH ~11
MeOH
20 h or so
Solvent : ethylene glycol
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Porphyrin substituents on heme in hemoglobin
Metallation of porphyrin
How do you know when the reaction is done?
Anything change at Fe?
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Molybdenum Reactions. List them and conditions
MoOCl2detc2
Mo2O3detc4
MoOS2detc2
MoOdetc2
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Fe and Ru Reactions. List them and conditions
FeCl(porphyrin)
Ru(bpy)2(L-pterin)
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Mechanism:
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an advertisement
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What’s the difference between pictures A and B?
A Bfrom X-ray crystallography from Chem 3D; “guessed” structure
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X-ray Crystallography: the closest we can get to photographing our molecules!
• single crystal (not a powder or many tiny crystals)• periodic array of atoms symmetrically oriented• produces accurate (almost) bond distances and bond angles
• The method:• see U.Penn X-ray Facility• see on-line X-ray Course• see illustration of Space Group Symmetry• one of my old structures (on Cu)
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A single crystal structure of a Mo molecule from my lab:
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Who wants to go see it done?