DIABETIC & HEART HEALTH 

OLEA25® 25% HYDROXYTYROSOL

ORGANIC OLIVE LEAF EXTRACT

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ANIMONUTRA.COM

Mission:To help address the problem of diabetes through clinically

proven, 100% natural, and MD community supported

Nutraceuticals focused on Improving Diabetic Health.

Founded on:If existing solutions  worked, Diabetes would not be reaching

epidemic proportions of 422 million globally.

Motto: Isn't it time to disrupt Diabetes?...

We Think So!

ANIMONUTRA.COM

ANTIOXIDANT

ANTI-INFLAMMATORY

CELLULAR LIFESPAN

MITOCHONDRIAL BIOGENESIS

Olea25® 25% Hydroxytyrosol

Bioactive Polyphenol of Olive Leaf & Mediterranean Diet

PurificationTechnology

Biotransformation Process

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Hydroxytyrosol (3,4-dihydroxyphenylethanol;

DOPET)

Olea25®  25% Hydroxytyrosol

ANIMONUTRA.COM

Heart Disease   Diabetes Cellular Function & Protection Neuroprotective

OLEA25® 25% HYDROXYTYROSOL

Anti-Inflammatory

 Reduces Acute and Chronic Inflammatory Biomarkers

Heart Disease

Hyperglycemia

Diabetes

Metabolic Syndrome

ANIMONUTRA.COM

Olea25® 25% Hydroxytyrosol 100% All Natural

Derived from Olive Leaf

Clinically Proven

MD Community

Supported  

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ANIMONUTRA.COM

Scientific-based Nutraceutical.

Olive Leaf Extract utilizing botanical

extraction technology.

Olea25® is manufactured under GMP and

ISO Certifications and the quality control

system guarantees each item on the

certificate of analysis and the traceability

from raw material to final extract.

Olea25®25% Hydroxytyrosol  

Diabetes: Impact & Complications

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Cardiomyopathy

Retinopathy

Nephropathy

Neuropathy

Peripheral Vascular

Disease

Complications

Total Costs Diagnosed Diabetes: > 245 billion (2012) > 174 billion (2007)

Major Costs: > Hospital Care   > Prescription Meds to Treat Complications ofDiabetes

People with diagnosed diabetes, on average, have medical

expenditures approximately 2.3 times higher than what

expenditures would be in the absence of diabetes. 

Diabetes

Occurs when there is an imbalance between indigenous anti-oxidants and free radicals. 

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Oxidative Stress

Reactive Oxygen Species(ROS)

ROS produced from: > Glucose oxidation > Glucose toxicity > Oxidative Phosphorylation

Free RadicalsLipid metabolism in diabetes increases Reaction Oxygen Species(ROS).

Antioxidant

Diabetes

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Superoxide causes insulin resistance - Type 2 Diabetes

Insulin resistance blocks insulin-based transport of glucose.

Excess high energy electrons in mitochondria.

In presence of oxygen produces Superoxide(free radical)

Superoxide is the trigger to block import of more glucose

Insulin resistance is cellular defense against sudden death from Superoxide and other free radicals.

Antioxidant

Improves glucose homeostasis (HbA1c)Improves plasma insulin levelsImproves insulin sensitivity Improves pancreatic β-cell secretion

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Benefits of Olive Leaf Polyphenols: Diabetes

Diabetes and Metabolic Syndrome  

“Supplementation with olive leaf polyphenols for 12 weeks significantly improved insulin sensitivity(15%) and pancreatic β- cell secretory capacity(28%) in overweight middle-aged men at

risk of developing the metabolic syndrome.”

See de Bock, et al(References) ANIMONUTRA.COM

Diabetes and Metabolic Syndrome  

Effects of Olive Leaf Extract supplementation is comparable to common diabetic therapeutics , and our results could have

clinical significance for patients with type 2 diabetes.

See de Bock, et al(References) ANIMONUTRA.COM

Diabetes and Metabolic Syndrome  

Olive leaf extract may represent an effective adjunct therapy that normalizes glucose homeostasis in individuals with diabetes.

ANIMONUTRA.COM

Olea25® 25% Hydroxytyrosol

Highest Antioxidant Capacity of Olive Polyphenols

Effective Scavenger of 5 common Free Radicals -

Superoxide, Peroxyl, Hydroxyl, Peroxynitrate and

Singlet Oxygen

15 X more powerful than green tea

3 X more more power than CoQ10

FDA Classified as Food

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References: Hydroxytyrosol Olive (Olea Europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged

overweight men: a randomized, placebo-controlled, crossover trial. de Bock M, Derraik JG,

Brennan CM, Biggs JB, Morgan PE, Hodgkinson SC, Hofman PL, Cutfield WS. PLoS One.

2013;8(3):e57622.

Olive Leaf  Extract as a Hypoglycemic Agent in Both Human Diabetic Subjects and in Rats,

Julio Wainstein, Tali Ganz, Mona Boaz, Yosefa Bar Dayan, Eran Dolev, Zohar Kerem, and

Zecharia Madar. Journal of Medicinal Food. June 2012, 15(7): 605-610. doi:10.1089/jmf.2011.0243.

Insulin Resistance is a Cellular Antioxidant Defense Mechanism, Kyle L. Hoehn, Adam B.

Salmon, Cordula Hohnen-Behrens, Nigel Turner, Andrew J. Hoy, Ghassan J. Maghzal, Roland

Stocker, Holly Van Remmen, Edward W. Kraegen, Greg J. Cooney, Arlan R. Richardson, and

David E. James. PNAS 2009 106 (42) 17787-17792. doi:10.1073/pnas.0902380106.

The Cost of Diabetes. American Diabetes Association,http://www.diabetes.org/advocacy/news-

events/cost-of-diabetes.html?referrer=https://www.google.com/#sthash.eNFCOMU3.dpuf