INVO Inventive Activity FY2019 - confidential...FILED PATENT APPLICATIONS BY TYPE FIG. 11 ISSUED...

INVO Inventive Activity FY 2019

2 NORTHWESTERN INVO

NORTHWESTERNINVENTIVE ACTIVITY

Figure 1 illustrates invention disclosure activity since 2002. In FY 2019, INVO processed230 invention disclosures.

Inventorship spans both campuses. Figure 2 represents the distribution of inventive activity by school. The McCormick School of Engineering (McC) and the Feinberg School of Medicine (FSM) have the largest shares, followed by the Weinberg College of Arts and Sciences (WCAS).

Figure 3 shows the distribution of inventions by category. Therapeutics had the largest share of the inventive output. It is important to note that many inventions in the areas of chemistry, computer science, and materials are considered platform technologies with undefined markets. For example, a new software invention might find applications in the future in a variety of markets such as energy, consumer, and biomedical.

FIG. 1 INVENTION DISCLOSURES, 2002-2019

2002 2004 2006 2008 2010 2012 2014 2016 2018 2020

Fiscal Year

0

50

100

150

200

Inve

ntio

n D

iscl

osur

es T

otal

91

184 185

189

170

116

166

195200

124

203207

230

210

211211212

137

INVO INVENTIVE ACTIVITY FY 2019 3

FIG. 2 INVENTIONS BY SCHOOL

0 10 20 30 40 50 60 70 80

Total Inventions Disclosed in FY2019

Biomarkers and Biomedical Research Tools

Energy & Sustainability

Engineering & Technology

Healthcare Devices, Tools and IT

Materials and Industrial Processes

Software & Services

Therapeutics

16.5%

32.2%

17.4%

16.5%

7.4%

4.3%

5.7%

FIG. 3INVENTIONS BY CATEGORY / INDUSTRY PIPELINE

4 NORTHWESTERN INVO

230 InventionsMultiple schools collaborated

on 53, or 23%, of these inventions.

Feinberg Schoolof Medicine

96 | 42%

Other

29 | 13%

McCormickSchool of

Engineering

91 | 40%

Weinberg Collegeof Arts and

Sciences

67 | 29%

FIG. 4COLLABORATION BETWEEN SCHOOLS


Boundary crossing ideas produced the most disruptive inventions, which are also most valued in the marketplace. Northwestern’s interdisciplinary approach is displayed by the co-inventorship activity among different schools and departments.

FIG. 5McCORMICK SCHOOL OF ENGINEERING INVENTIONS BY DEPARTMENT

0 5 10 15 20 25 30 35 40


Administration

Biomedical Engg

Chem & Biol Engg

Civil & Environmental Engg

Elect Engg & Computer Sci

Elect Engg & Computer Sci

Ind/EnggMgmt Sci

Materials Science & Engg

Mechanical Engineering

16%

19%

19%

41%

13%

1%

1%

3%

2%

FIG. 6WEINBERG COLLEGE OF ARTS AND SCIENCES INVENTIONS BY DEPARTMENT

0 5 10 15 20 25 30 35 40 45 50 55 60


Anthropology

Chemistry

Interdept Bio Sci Pgm

Molecular Biosciences

Neurobiology

Physics & Astronomy

Psychology

87%

1%

1%

3%

4%

3%

1%

Figures 5, 6, and 7 illustrate inventive activity within each school.

6 NORTHWESTERN INVO

FIG. 7FEINBERG SCHOOL OF MEDICINE INVENTIONS BY DEPARTMENT

0 1 2 3 4 5 6 7 8 9 10 11 12 13


Anesthesiology

Biochemical & Molecular Genetics

Cancer Center

Cardiac Surgery

Cardiology

Dermatology

Emergency Medicine

Endocrinology

Feinberg Cardio Res Inst

Gastroenterology

Hematology Oncology

Hepatology

Medicine

Microbiology-Immunology

Nephrology

Neurological Surgery

Neurology

Obstetrics & Gynecology

Orthopedic Surgery

Otolaryngology

Pathology

Pediatrics

Pharmacology

Physical Med & Rehab

Physiology

Preventive Medicine

Psych & Behavioral Science

Radiology

Surgery

Thoracic Surgery

Transplant Surgery

Urology 10%

10%

11%

1%

4%

1%

1%

3%

1%

3%

6%

2%

3%

3%

2%

1%

1%

2%

1%

1%

4%

7%

8%

3%

3%

3%

1%

3%

2%

2%

3%

7%


FIG. 8INVENTORS AMONG TENURED AND TENURE-ELIGIBLE FACULTY

Figure 8 represents the gender distribution of tenured and tenure-eligiblefaculty and the percentage who disclosed inventions during FY2019.

Weinberg College of Arts and Sciences percentages represent faculty from the departments of Anthropology, Chemistry, Molecular Biosciences, Neurobiology and Physics & Astronomy.

As an example, the first bar in Figure 8 shows that 7% of the total female tenured and tenure-eligible faculty at FSM have disclosed inventions during FY2019.

In FY 2019, McC female inventors increased by 50% over the previous year. This increase contributed to McC female inventorship growing to 30% of the McC female tenured and tenure-eligible faculty.

BY PROMOTING DIVERSITY IN OUR ECOSYSTEM, MORE NORTHWESTERN INNOVATIONS CAN ENTER THE MARKET.


PATENTSPatent filing grew in FY19 and surpassed 500. Figure 9 shows patents filed in FY19 per school. Patent filing is consistent with the invention disclosure activity reported in Figure 2. Figure 10 illustrates the breakout of patents filed in FY19. Figure 11 illustrates that issued patents span multiple disciplines and markets.

Patent Types

Provisional patents: Approximately 60% to 70%of all invention disclosures are filed as provisional patents; approximately 50%–60% are converted into non-provisional patents within a year.

Filing a provisional patent application before filing a Utility application presents several advantages:

• Relatively inexpensive and allows the inventorto spend one year gathering more data, resulting in

a stronger patent application• Allows INVO to conduct a more in-depth

commercial assessment of the invention and identification of potential licensees

• Delays the formal filing date, which results in alater patent expiration date

Non-Provisional (Utility) patent applications: The filing of a Utility patent starts the official examination process with the USPTO to determine if the invention is patentable. The USPTO review of a patent application can take several years.

PCT applications: A PCT is an international treaty with more than 145 Contracting States. The PCT makes it possible to seek patent protection for an invention simultaneously in a large number of countries by filing a single “international” patent. A PCT application must be followed up within 18

FIG. 9 FILED PATENT APPLICATIONS BY SCHOOL

10 NORTHWESTERN INVO

501 Patents FiledMultiple schools collaborated

on 136, or 24%, of these applications.

Feinberg Schoolof Medicine170 | 34%

Other52 | 10%

Weinberg Collegeof Arts andSciences

160 | 32%

McCormickSchool of

Engineering275 | 55%

months by entering into national or regional phases to more patents. Foreign prosecutions are very expensive. INVO files in specific countries (National Phase) only when there is a licensee for the patent.

Continuing patent applications (CIP): These are patent applications that follow and claim priority to an earlier filed patent application.

EPO Validation: Granted European patentsthat are in the process of validation in individual states.

Divisional patent applications: Patent applications with claims that were divided out of the original filed application and which must be re-submitted as a separate application.

0 20 40 60 80 100 120 140 160 180 200 220

Patent Applications Filed in FY2019

CIP

Continuation

Divisional

EPO

EPO Validation

Nationalization

PCT

Provisional

Utility

39.1%

20.1%

17.6%

0.8%

0.2%

3.9%

8.7%

0.8%

8.9%

FIG. 10FILED PATENT APPLICATIONS BY TYPE

FIG. 11ISSUED PATENT APPLICATIONS BY CATEGORY / INDUSTRY PIPELINE

0 10 20 30 40 50 60 70

Patents Issued in FY2019

Biomarkers and BiomedicalResearch Tools

Energy & Sustainability

Engineering & Technology

Healthcare Devices, Toolsand IT

Materials and IndustrialProcesses

Software & Services

Therapeutics

14%

24%

10%

38%

8%

2%

3%


COMMERCIALIZATION RESOURCES AT NORTHWESTERN


Translating innovative technologies from the lab to the market takes time and resources. It’s an arduous and complex but necessary journey. The majority of advanced technologies out of the university, including computer software, electronics, medical devices and nanotechnology, requires research, market validation, testing, and much more to reach the public’s hands.

INVO and Northwestern University at large support the commercialization of technologies throughout the earlier ideation and proof of concept stages as well as the initial phases of new company formation. Resources spanning translation, diligence, and access to funding and physical space are outlined here.

IDEATION NU SPINOUTPROOF OF CONCEPT| |

The GarageNUvention

Entrepreneurs-in-ResidenceWildfireINVOHub Startup Toolbox & Core Subsidies Lakeside DiscoveryNewCuresNCAI-CC / CBC

Catalyst Award

INVO Practicum Internship

INVOForward

The GarageINVOHub Stage Zero

1871 | MATTER | mHUB

VentureCatNUseedsN.XT

Kellogg Classes

NewCures

NCAI-CC / CBC

TRAN

SLAT

ION

DILIG

ENCE

FUND

ING

SPAC

E

Commercialization ClinicCommercialization Seminar

INVOReach

NUventionSBIR/STTR Consultation

Lakeside Discovery

Anonymous Gifts

FIG. 12FY 2019 STARTUPS BY SCHOOL


WE THRIVE AT THECROSSROADS OF

ACADEMIC RIGOR ANDENTREPRENEURSHIP

Sep 1, 18 Nov 1, 18 Jan 1, 19 Mar 1, 19 May 1, 19 Jul 1, 19 Sep 1, 19 Nov 1, 19 Jan 1, 20 Mar 1, 20

2018

September

November

December

2019

January

April

May

June

August

Polaro MaterialsProf. Elad Harel\WCAS

Angiotensin Therapeutics, Inc.Prof. Daniel Batlle\FSM

Sibel Inc.Profs. John Rogers, Steve Zu\McC\FSM

Inari Health, IncProf. Apkar Apkarian\FSM

Cytostrata BiosciencesProfs. Guillermo Ameer, Jason Wertheim\McC\FSM

Yobee Care, Inc.Prof. Ruchi Gupta\FSM

Sonica, LLCProf. John Rogers\McC

Amphix Bio, Inc.Prof. Samuel Stupp\McC

Volexion, Inc.Prof. Mark Hersam\McC

CycloPure, Inc.Prof. William Dichtel\WCAS

ASP Health, Inc.Prof. Vadim Backman\McC

Temprian Therapeutics, Inc.Prof. Isabelle Le Poole\FSM

FIG. 13FY 2019 STARTUPS TIMELINE

APPENDIX


BIOMARKERS AND BIOMEDICAL RESEARCH TOOLS PIPELINE

Phase Title1-BIOMARKERS A Genetic Marker for ALS

A pre-school biomarker for literacyAssociation of Serotonin2c Receptor Polymorphisms with Antipsychotic Drug Response..Biological Marker For Auditory Processing (Bio-MAP)Biological Markers for Diagnosis of Diseases Associated with Major DepressionBiomarker for ColitisBiomarker for Early Stage CancersBiomarker for Female Egg QualityBiomarkers for Prostate DiseaseBiomarkers for PTSD and DepressionBlood and Biopsy mRNA Expression Signatures to Distinguish Major Causes of Rejectio..Blood biomarker analysis for early detection, treatment response and disease progressi..Cardiac Stress Test with MRIDepression and Treatment Response PredictorDetection of antibody reactivity towards deamidated proinsulin for risk prediction and di..Genetic markers in GRB10-DDC region (or 7p12.2) predict Treatment Resistant Schizop..Lipid Denaturation as a Marker and Therapeutic Target of Ovarian Cancer Stem CellMarker for Chronic Pelvic Pain IMarker for Chronic Pelvic Pain SyndromeMarker for Neuromuscular DisordersMethod for Screening P. Aeruginosa StrainsMolecular Signature in the Peripheral Blood for Sub-Clinical Acute Kidney Transplant Re..Neural Biomarkers in Nasal Exhaled BreathNeurodegenerative Disease BiomarkersPerinucleolar Compartment as a Cancer MarkerPlatform-And Sample-Specific Molecular Signatures of Kidney Transplant RejectionPNC Cancer Diagnostic (non-breast cancer)PTSD Blood TestRBFOX1/A2BP1 and related proteins as drug targets for treatment of psychiatric disord..Small Molecule Antiviral TherapyTracking Reporter GeneUse of Maspin as an Anti-ROS Scavenger Against Cell Proliferation, Inflammation, and ..UTI Management

2-NUCLEIC ACID A Universal Phosphoramidite For The Preparaton Of TosylatedClock gene cDNAhsp70.1pr-luc PlasmidNuclear Lamins Expression VectorpAN1: ElectroTfm of ClostridiumpHT plasmidsTimeless gene cDNA

3-ANTIBODY alpha 3 laminin, mousealpha 4 laminin, mouseAnti-ALP1 AntibodyAnti-macrophage monoclonal antibodies (CD31, CD87, CD15)Antibody for Tubulointerstitial NephritisBRAP AntibodyCD 13 antibody mousegamma 3 laminin, mouseHard-Tip Active Spring LithographyHemidesmosome (BP180) mouseHemidesmosomes (BP230) mouseHSF1 and HSF2 antibodies, ratHSP-70 antibodies mousehu Tau C-term, mouseImportin beta1, mouseInfluenza M2 protein, mouseLamin A and C antibodies, rbMetabolic Antibody Discovery and DevelopmentMolecular Control over Exosomes for Isolation, QuantificatiomtHSP-70, BiP/grp 78 mousePGSL-1, mouserat laminin -332 alpha3 subunit, mouseScarpulla Lab Antibodies - 6 AntibodiesTau Isoforms, mouseTau N Terminus, mouseTau Tyr18 nitrosylated, mouseTNT1: Tau PAD region, mouseTOC-1 mouse antibodyVascular endothelial cell Ag, m

4-CELL LINE E. coli from human prostateHSV-2 333/Gal and HSV-1 KOS/tk12MM.1 Myeloma cell linesRetinal Muller Cell lineS.cerevisiae H4S47C INVO INVENTIVE ACTIVITY FY 2019 17

Phase Title5-ANIMAL MODEL An 5 - ANIMAL MODEL For Uterine Fibroid Embolization

Biobarcodes Based on Oligonucleotide-Modified ParticlesBMP4 Tg mice: FOPClock Tg mice: diabetesDyrk1a conditional knockout mouseEl-Kras Transgenic, PDEF Knockout MicehSOD1G93A-UeGFP Tg mice: ALShTAAR Tg miceKnockout Mouse Model Of Cognitive DeficitsMLCK 210 KO miceMt Clock Tg miceMutant Mouse Line C57BL/6J-FahswingshiftMutant Mouse Line C57BL/6J-Slc2a4twiggyNanoparticle Based Biobarcodes for the Ultrasensitive DetectPEDF-null MousePer2 Luciferase Tg miceSOD Tg miceTransgenic Mouse for Amyloid PathogenesisTriple transgenic mice for triggering inducible hepatocyte apoptosis and uses thereof as ..U19 Knockout MiceUchl1-eGFP Tg mice:ALS

6-MISCELLANEOUS 3D Transfected Cell Arrays3D Transfected Cell Arrays IIA Highly Productive One-Pot System for the Incorporation of Non-Standard Amino Acid..A method to create a library of electrophilic compounds for screening using virtual docki..Acinetobacter Baumannii Transposon LibraryAn Elevated-Pressure, Freeze-Thaw Method For Lipsome Gas EncapsulationAntibody to Microtubule Associated Protein Tau; Clone Tau-7At Home Menopause TestCell-free glycoprotein synthesis (CFGpS) in prokaryotic cellCell-free protein synthesis driven metabolic engineering (CFPS-ME)Cell-Free Yeast Protein SynthesisDetergent-free membrane solubilizationDevelopment of an Ex Vivo Female Reproductive Tract in a 3D Microphysiologic SettingEffective Mucosal Blood Vessel Size and Oxygenated Hemoglobin Concentration in the ..Elastic Backscattering Spectroscopic MicroscopyEnucleation of Feeder Cells and Egg CellsEx Vivo Female Reproductive SystemFaster and more efficient two step sequence specific nucleic acid captureFemale Fertility TestFluorescent Sensors for ZincGlycosylated ligands for exosome targetingHigh Throughput Transcription ProfilingHydraulically Actuated Patch Clamp Electrode SystemIntegrated microfluidic tissue culture system for use with female reproductive tissuesIrreversible inhibitors of Nedd4-1 polyubiquitinationLamin B1: Marker for Replicative SenescenceMaking Tethered RibosomesMechanism-Based Small Molecule Cross-Linkers of HECT E3 Ubiquitin Ligase - Substr..Method for Making RibosomesMethod of in vitro ribosome synthesis and evolutionMethods for Activating Natural Energy Metabolism for Improving Yeast Cell-Free Protein..Methods for Improved in vitro Protein Synthesis with Proteins Containing Non Standard ..Nanocytological and Molecular Analysis of Fecal Colonocytes for Colon Cancer Screeni..Nanopatterned Extracellular Matrices Enable Cell-Based Assays with a Mass Spectrom..Neuronal cell line with suppressed endogenous sodium currentNon-toxic cell staining probeNovel Photocrosslinking Reagents to Map Protein Protein Interfaces in VitroPlanar Two Dimensional Biofilm Reactor for Flow-Field-BasedPreclinical Model of Multiple SclerosisProof of Concept of Engineering a Yeast Receptor to Detect New Peptide LigandsProteasome adaptors - degradonsRaman Spectroscopy for Anthrax DetectionReverse Transfection TechniqueScaffolds for Artificial OvaryScalable Cell Sorting via MotilityTranscription Factor Analysis: Transfected Cell ArrayTwo gRNA method for homologous recombination-based gene targetingUbiFlu-Novel Class of Fluorescent Probes to Screen for Inhibitors/Activators of HECT E..Yeast-Free Protein Synthesis & By-product Removal

HEALTHCARE DEVICES, TOOLS & IT PIPELINE

Phase Title1-CONCEPT 3D printed Intraocular lens

3D Printing of Endovascular StentsA Novel Medical Device that Differentiates Stroke from AcuteAdjustable Banding Device for AVFAgility TrainerAmbulatory blood pressure DeviceAnalysis of Multiplexed Bead-Based AssaysCartilage Coupled PeptidePolymersCatheter for Gene TherapyCentral Dialysis Catheter with Balloon Technique to PreventHeart Valve Repair Rings, with Sizers and Holders, which AllHemodialysis Needle with a Safety TipImaging & Therapeutic NanoconjugatesImpedance planimetry for Assessment of Cervical Ripening duriPSC-EC Performance Enhancement Via SIRT1 OverexpressionLeft Atrial Appendage Occluder DeviceMethod to measure Perfusion and Leakage Parameters in a SingNanostructures for Alzheimer's DiagnosisReal Time and High Resolution Spatial Mapping of Kidney FiltRetrievable scaffolds for beta cell replacement therapiesScar-Free Tissue RegenerationSealants for Fetal Membrane RepairSelf Assembled BioadhesivesSimultaneous covalent and non-covalent polymerizations for hSynthetic antigen compositions for detecting antiphosphatidy

2-LABORATORYPROTOTYPE

A Biological Marker for ConcussionA Heavy Metal Blood Collection Card for Screening Newborns and ChildrenA Universal Method for Fabricating Complex Metallic StructurAbnormal Scar Identification with Spherical Nucleic Acids TeAdaptable Ankle Foot ProsthesisAdvanced retinal blood flow measurementAligned Nanofibers for Nerve RegenerationApp for Movement DisordersBedside Pulse Lavage Project ModificationsBiodegradable Drug Delivery [Drug Releasing Tubes for Tissue Engineering]Biomimetic High Density Lipoprotein Nanoparticles as CatalytCardiac Tissue AblationChalco-Halides for Medical Imaging [Materials for X-Ray & Gamma Ray Detection]Collagen Binding Heparin for Anti-thrombosis and Re-endothelColorectal Cancer Screening DeviceCsPbX3: Perovskites for gamma-ray detection applicationsDevice for Isolating an Analyte from a SampleDigitally Adjustable Phrenic Nerve (DAPhNe) StimulatorDNA Intercalators with Duplex-Selective Luminescence EnhacemDOPA Nanoparticles for Diagnosis and TherapyElectronic Biochip SystemElectrostatically triggered partially denatured albumin hydrExtracellular Matrix Protein-Coated Scaffolds Promote The ReExtracellular Matrix With Anticoagulant Properties for Tissue EngineeringFirst In Vivo Surface-Enhanced Raman Glucose SensorGel Scaffolds of BMP-2-Binding Peptide Amphiphile NanofibersHeavy Metals in Dried Blood SpotsHigh Precision Diagnosis of ADHD Based on Functional NeuroimHigh Throughput Partial Wave Spectroscopic MicroscopyHybrid Prosthetic LegHydrogels for improved tissue graft survivalImplanted Surgical Film for the Reduction of Post Surgical ComplicationsIntrinsic-contrast super-resolution optical microscopeiSOCTIVC Filter RemovalLeft Ventricular Apex Surgical TechnologyLipid Nanoparticles for Measuring Chronic and Acute ResponseLow Power Cochlear ImplantLung-inspired microfluidic platelet bioreactorMacromolecular MRI Contrast AgentsMaterials that Promote Bone RegenerationMethod For Preparing High Aspect Ratio Peptide Amphiphile FibersMethod for the Mapping and Quantification of In-vivo Blood FMethod, system, and apparatus of metabolic optical coherenceMicrofluidic platelet bioreactor

Phase Title2-LABORATORYPROTOTYPE

Mobile Opioid Dosing simulatorMRE Passive DriverMultimodal T1-T2 MRI Contrast AgentsNanofarbicated Glucose Sensor [SWCNT Glucose Monitor]Naso-Seal DeviceNICU2HOME smartphone applicationNon-Contact Liquid Droplet Manipulation MethodNormalization of MRI for Imaging of Gene Expression SignaturNovel Chalco-Halides for ImagingOptical and Acoustic ImagingOptical Coherence Photoacoustic MicroscopyParylene membranes for drug deliveryPeptide Conjugated MRI Contrast AgentPerovskites for gamma-ray detectionpH Responsive Self-Healing HydrogelsPhotoluminescent Panthenol Citrate Biomaterials with AntioxiPoint of Care Diagnostic ToolPrinting 4D Composite Scaffolds for Bone GenerationProsthetic Foot with an Adjustable Flat RegionProtein-Based Contrast Agents for MRIResorbable Wireless Bone StimulatorSoft Materials for BioprintingSoluble Membrane Protein Libraries in NanodiscsSpatiotemporal Background Phase Correction for Phase ContrasSpectroscopic Super-resolution MicroscopyStroke Rehabilitation SystemStructured Illumination MicroscopySupramolecular GlycosaminoglycansTargeted therapy for the prevention of restenosis in the carTechnique for disaggregating & estimating Electronic HealthThe Hidden Markov Spike Generator for Cochlear ImplantsThe LaserNanoPump (LNP)Thermoresponsive Cell Adhesive Bioresorbable DressingTriple Balloon CatheterVirtual Electrophysiologic Testing For Cardiac Arrhythmia RiWearable for Ambulatory Blood Pressure Monitoring

3-COMMERCIALPROTOTYPE

3D SutureA "Skin-like" Wearable Sensors for Sweat Loss AnalysisA Fluorometric Assay to Measure Cholesterol Binding KineticsAnnuloplasty Ring SizerAnthrax DetectionAuditory TestAutomated fMRI for ClinicBioscaffolds for Replacement OvariesBrain Wave Processing to Enhance SleepCell Therapy for DiabetesCircumferentially Constructive Annuloplasty RingDiaphragm-based Hybrid Prosthetic Vacuum Pump for Transfemoral Amputees..Evaluating Impact of Oxidative Stress on AF ElectrogramsFlexible Electronic Medical DeviceGas Sensor for Smart Chest Tube DrainageHybrid Prosthetic Vacuum Pump for Transfemoral AmputeesImplantable Biomedical SensorsLiquid Cast Biodegradable Drug Delivering Arterial StentMethod for Detecting and Quantifying a Target Molecule in aMRI-Perfusion and Diffusion MismatchNanodiamond ConjugatesNeonatal Abdominal Surgery TrainerParticles For Detecting Intracellular TargetsPartition Layer for Raman NanobiosensorPhotodetector for Infared ImagingPoint of Care DiagnosticsQuantification of Cerebral PerfusionRadio Frequency Soft Tissue Ablation SystemRaman Biosensor for Multianalyte DetectionRF Ablation ProbeRobust Semi-Automated Pulse Wave Velocity Estimation From 4DRoom Temperature Synthesis and 3D-Printing of Bioactive "ElaSNR Improvements for Multi-Slice MRIThin, Soft, Skin-Mounted Microfluidic Networks with CapillarVirtual Electrophysiologic TestVocal Cord Medialization

4-HUMAN TESTING AF Electrogram Analytics SoftwareAtrial Fibrillation Diagnostic SoftwareBedside Wound Pulse Lavage

HEALTHCARE DEVICES, TOOLS & IT PIPELINE (CONT)


Phase Title4-HUMAN TESTING Bi-Modal Ankle-Foot Systems for Standing and Walking

CA Diagnostic with MicroscopyEndoscopic CA DiagnosticEquilibrium-Point Prosthetic And Orthotic Ankle-Foot DevicesHearing Aid InterfaceHIV DiagnosticsImproved methods of neurological assessment with thermoregulImprovements to Passive Ankle-foot Prosthesis Capable of AutMedical AdhesivesMethod and User Interface for Hearing Aid ControlPolymers for Vascular DiseasePre-Free Colon CA ScreeningRehabilitation Robotics

5-APPROVAL &MARKETING

Childress AnkleEsophageal PanometrylntelliCare: Mobile apps for depression and anxietyPanometryPoint of Care Protein DiagnosticsRobotic Arm for Orthopedic SurgerySticky FlareSurgical Cement Mixer Apparatus

THERAPEUTICS PIPELINE

Phase Title1-NEW TARGETS Adoptive Cell Therapy using SNAs

Antibiotic-Coated NanoparticlesCompositions and Methods for the diagnosis of major depressive disorderConjugation of Peptides to SNAs Using Traceless LinkersCXCR4 ModulatorsEngineering Nucleotide Sequence or Composition to Promote EnFacile synthesis of micellar spherical nucleic acids using tFemale Fertility TreatmentFGF23 Normalizing MethodsGene Therapy: Anti-DepressionHDL-like Nanoparticles: InfectionHDL-NP-NO (CV)Hydrogel Wound Dressing With Cu IonsImmunotherapy: Macular DegenerationKinase Inhibitors: CancerLipophilic nanoparticles for drug deliveryMAPK Compounds: CNS DisordersMLCK InhibitorsNanopatterning for Controlling Cell CytoskeletonNanostructures for Medulloblastoma and other CNS cancersNitric Oxide Releasing High Density Lipoprotein-like NanoparticlesPoly (Lactic-co-Glycolic Acid) (PLGA) Spherical Nucleic AcidPro-Drugs: StreptococcusPTPRD as drug target for treatment of schizophrenia and othePulmonary intravascular non-classical monocytes mediate lungScar-Free Tissue RegenerationScreen for Covalent DrugsSelf-manageable Abnormal Scar Treatment with Spherical NucleSirt1 Gene Therapy For Improved Wound HealingSirtuin InhibitorsSpherical Nucleic Acids with Sheddable PEG LayersStructure-Function Relationships in the Development of ImmunThermoresponsive Adhesive DressingTricyclic carbogenic molecules as anticancer agents

2-HIT TO LEAD A bacterial toxin that is a Ras specific proteaseA Concise Route to the Chiral Pyrrolidine Core for InhibitorA new CNS-available formulation HDACi for management of chroA Novel 5-HT5A Receptor Antagonist for Treatment of PsychiatA novel treatment of sleep-wake disorders by consuming modifAMP Analogs-Cell Proliferative DisordersAMPA Receptor Antagonists: Neurologic DiseasesAntibacterialsApplication of Honokiol in Anti-Ototoxicity and Hearing ProtAptamer-Loaded, Biocompatible Nanoconstructs for Nuclear-TarAromatic heterocycles Inhibitors of Mnk1 and 2Bladder RegenerationBone Marrow Mesenchymal Stem Cells with CD34+ HematopoieticCD154 Trimer Stabilization: ImmunityChromatin Therapy to Sensitize CA CellsComposition and Method for Preventing or Treating a TauopathComposition and Use of PLGA-PEG/PEI nanoparticlesCompositions and Methods for Treating Alzheimer's DiseaseCompositions and Methods to Reduce Inflammatory ResponsesCompositions Comprising Epigenetic Modifying Agents and MethCompounds: Neurologic DisordersDentin Matrix Protein 1 Ameliorates Chronic Kidney Disease bEnantioselective conjugate additions of aminesEpstein-Barr Virus InhibitorsFFAR2 Agonists: Type 2 DiabetesG Protein Inhibitors: CardiovascularHIV TherapeuticsImmunotherapy for Treating Age-Related Macular DegenerationInhibition of Mast Cell Function as a Therapeutic for ChroniInhibitors Of The Mevalonate Pathway Of Streptococcus PneumoIntramolecular Hydrogen Bonding: A Strategy to BioavailableIon Channel Manipulation: Parkinson'sIron Chelator as a Treatment for Cardiomyopathy, Heart FailuMaspin: Bone DisordersMegakaryocytic Leukemia TreatmentMegamolecule Synthetic AntibodiesMethod for the Preparation and Characterization of DNA-IronMethods of Treating Brain Disorders or Identifying BiomarkerMethods of Using (1S,3S)-3-amino-4-difluoromethylenyl-1 cyclMethods to Reduce Polyposis and Colorectal CancerMolecules to Treat InflammationNanodiamond-Mediated Delivery of Water-Insoluble TherapeuticNanomolecules for the Treatment of Inflammatory Bowel Diseas

Phase Title2-HIT TO LEAD Noise based coding in cochlear implants

Novel RNA Therapeutic Candidate for Fibrotic DiseasesNylon-3-copolymers as Functional Mimics of Lung Surfactant Pp38MAPK Modulators of CNS Pathology and Cognitionp50 Compoundp53 Reactivators: CancerPeptide-Oligonucleotide Chimeras (POCs) as Programmable BiomPeptides for PEDFPeptides: CancerPlaque Digestion: CardiovascularProtein FoldingS.epidermidis Lipotechoic Acid (SELTA) for immune modulationSelf-Management of Abnormal Scars via Transdermal Delivery oSmall molecule disruption of the Super Elongation Complex anSmall Molecules against ALSSoft Materials for BioprintingSonic hedgehog regulation of human rhabdosphincter muscle: PStatin for Hearing Loss Prevention & TherapyStem Cell Signaling Molecules for Cancer TherapiesSubstituted pyrazoles as MYC targeting agentsSubstituted Pyrrolo[2,3-d]pyrimidines for the Treatment of CTargeted therapy to stop hemorrhageTGFb Inhibitor TransgeneThe application of myosin 9 family members and Slit-Robo-MyoTherapeutic targeting of MLL1 proteolytic cleavage by taspasTreating Prader-Willi Syndrome and Seizure DisordersTriggered Release Arsenic: CancerUrinary Tract Infection VaccineUse of 2-(4-acetoxyphenyl)-2-Chloro-N-Methyl-Ethylammonium CUse of REDD1 inhibitors (regulated in development and DNA daUse of Self-Assembling Peptide Amphiphiles to Prevent Tumor

3-LEADOPTIMIZATION

2-Aminopyridine Based Selective Neuronal Nitric Oxide Syntha2-Aminoquinolines as Novel, Potent, and Selective Inhibitors9-ING-41-CancerA vehicle to introduce selected bacteria to the skin, scalp,Alzheimer ImmunotherapyAmino-alkoxyester-linked peptides having anti-angiogenic andAminopyridine Dimer Compounds, Compositions and Related MethAn Improved Synthesis of Novel Pyrrolidine Inhibitors of NeuAnti-angiogenic peptides and their esters for treating canceAnti-Inflammatory Nanomolecules for Tissue RegenerationAntibody and variants thereof for inhibiting Nodal-dependentArsenoplatins for Cancer TreatmentArylazanylpyrazolone Inhibition of Mutant SOD1 Mediated Cytob lactamase Inhibitors: AntibioticsBacterial NOS Inhibitors as AntibioticsCancer Treatment with phospholipid particles containing a cyCarbohydrate Enhanced Nanoparticles for Immune ModulationCombination Therapy for Cardiac ArrhythmiasCombination Therapy for Treatment of CancerCombinations of NMDAR Modulating CompoundsDevelopment of GLUT4 Selective Inhibitors for Cancer TherapyExosomes: Cholesterol ModulationGABA Aminotransferase Inactivator for the Treatment of Addiction and Hepatocellular C..Gaucher's Disease (Glucoceribrosidase)Gene Silencing EnhancersGene Therapy: Atrial FibrillationGlucocerebrosidase ModulatorsGLUT Antagonists Cancer 2GLUT Antagonists: Cancer 1Hepatic Cell-Mediated Cardioprotection in Ischemic InjuryHerpes Virus Vaccine and Oncolytic VectorsHigh density lipoprotein functionalized magnetic nanostructuInactivators of Toxoplasma gondii Ornithine AminotransferaseInhibiting Cancer Cell MotilityInhibitors for Triple Negative Breast CancerInhibitors: LeukemiaKinase InhibitorsLiposomal Statin FormulationLiposome Coated NanostructuresLiposomes for Bioactive Gas Delivery and MethodologyMagnetic-Lipid Nanocapsule (MLNC)- A novel nanoconstruct forMalaria ProphylaxisMaspin Protein Mimics for Cancer TreatmentMetarrestin-Akzheimers, Drug ToleranceMethod for the synthesis of heteroyohimbine natural productsMethod Of Using Mitotically Inactivated Embryonic Stem Cells

THERAPEUTICS PIPELINE (CONT)

Phase Title3-LEADOPTIMIZATION

MW-150-Alzheimers (p38 kinase)Nanoparticulate Arsenic Platinum DrugsNeurodegenerative Disease TherapyNeuroprotective TherapeuticsNovel autophagy-inducing small molecule ML246 as a treatmentPeptide Amphiphiles for Neurite OutgrowthPotential treatment of corneal vascularizationPreparation of Pyrimidine-2,4,6,-trione Derivatives and TheiProgrammable Polypeptide for siRNA and Nucleic Acid DeliveryPyrimidine and fused pyrimidine compounds as ß-glucocerebrosPyrrolopyrimidine compounds and their applicationsRNA-directed DNA Cleavage & Gene EditingRNAi Inihibitor: Haem Peroxidase (bundled, take this box off pipeline)Scaffold Delivery of Antigen-Specific Suppressor Cells for CSelective Neuronal Nitric Oxide Synthase Inhibitors with AzoSelf-Assembling Gel System For Treatment Of Myocardial InfarSmall Molecules: Parkinson's DiseaseSubstituted fused pyrrolo-diazepinones and uses thereofTargeting of Nanoparticles with the Antibody ATN-291Targeting Stem Cell Signaling Molecules for New Cancer InterThiophene-2-carboximidamide Based Selective Neuronal NitricTLR4 Inhibitors for Scleroderma TherapyUse of ECDI-fixed Cell Tolerance as a Method for PreventingUse Of Stem Cell Factor Alone Or In Combination With GCSF ToUsing toxic RNAi active sequences embedded in genes in the hUsing Triplet Repeat siRNAs to Selectively Kill Cancer Cells

4-PRE-CLINICALDEVELOPMENT

3crx98-MetastasisA General Method for Acheiving Nucleic Acid-Nanoparticle ConBiocompatible Infinite Coordination Polymer Nanoparticle-Nucleic Acid ConjugatesBiomimetic High Density Lipoprotein Nanoparticles to ControlBladder RegenerationChronic pelvic pain vaccineCompositions and Methods for Antigen-Specific ToleranceCrosslinked Nucleic Acid Live Cell Diagnostics and TherapeutDefining the Alloreactive T Cell Repertoire Using High-ThrouDisplay of affinity domain-based targeting proteinsDNA-directed assembly of protein crystals from protein/DNA core-shell nanoparticlesE. Coli Isolated from Human ProstateEnhancing the stability and immunomodulatory activity of lipFlavanones & Chromanones: CancerGABA Analogues: Hepatocellular CancerGlycosides for CancerHeparin-Binding Peptide Amphiphile for Cardiac ConditionsHeteroaromatic Selective Inhibitors Of Neuronal Nitric OxideHuman MelanomaInflammation ModulatorInhaled formulation of small molecule inhibitor of Wnt/beta--cateninInhibition of Bacterial Transcription by Polyvalent OligionuLiposomal Particles, Methods of Making Same and Uses ThereofMedical FoodMetarrestin-Metastasis (autophagy)Mixed Monolayer Gold Nanoparticles for Cancer TherapeuticsNanoparticle Supported Lipid Bi-Layer Bio-Mimetic StructuresNitric Oxide Synthase InhibitorsNOS Portfolio InhibitorsNOS Targeting: NeurodegenerationNovel autophagy-inducing natural compound Rg2 as a treatmentNucleic Acid-lipoprotein Nanoparticles for Therapeutic UseNumonafide: Cancer TherapyOligonucleotide Loading on Silver NanoparticlesPeptide Conjugated Particlespeptide vaccine for lupusPeptide-coupled Carboxylate-Surface-Functionalized BiodegradPeptide-coupled Nanoparticles to Treat Autoimmune Disease, Transplant Rejection & All..Peptides: Immune tolerancePotent and Selective Neuronal Nitric Oxide Synthase InhibitoPreventing Scar FormationPreventing UTI SymptomsProtein/oligonucleotide core-shell nanoparticle therapeuticsScaffolds for nNOS InhibitionSelf-Assembling NanovirusSensitization to SteroidsSmall Molecules against Hepatocellular CarcinomaSmall Molecules CNSSubacute Administration of NMDA Modulators Alone or in CombinationSynthesis of Spherical Nucleic Acids via Self-Assembly of Nu

Phase Title4-PRE-CLINICALDEVELOPMENT

Tau Monoclonal AntibodiesTemplated Spherical High Density Lipoprotein NanoparticlesTopical Wound Treatment

5-CLINICAL TRIALS Antisense Molecules for Wound HealingAST-005 -Psoriasis TNFAST-008- Tumors (Chkpoint inhibitor)Controlling Immune Response using the Polyvalent NanoarchiteDetection, Discovery and Therapeutic Methods in Insulin ProductionGene Regulation with NP-Nucleic AcidGene Regulations with Polyvalent siRNA-Nanoparticle ConjugatesGLYX-13: Depression and PainGold Nanoparticles for Templated NanomaterialsGold Nanoparticles For TherapeuticsInhalable and Intranasal Formulations of Neuroactive PeptideLead Compounds For Neurodegeneration and NeuroinflammationLocked Nucleic Acid-Nanoparticle ConjugatesMethod to Control Dopaminergic Neuron PacemakingMethods of DepressionMethods of Identifying Compounds for Treating Depression and Other Related DiseasesMethods of Treating Conditions using Azetidinone CompoundsMethods of Treating or Ameliorating MigraineModulating Uptake of Olignucleotide-modified NanoparticlesMultifunctional Peptide And oligonucleotide Nanoparticles For Gene RegulationMultiple Sclerosis TherapyNanoparticle Conjugates as Anti-Glioma TherapeuticsNanoparticles For Control Of DrugsNMDA Receptor Agonists and Uses ThereofNYX2925- Pain Traumatic Brain InjuryNYX-783-CNSNYX-xxx-CNSOligonucleotide Gold Nanoparticles for mRNA Regulation and DOligonucleotide Specific Uptake of NanoconjugatesOrgan TransplantationSecondary Structure Stabilized NMDA Receptor ModulatorsSmall Molecules for Tourettes SyndromeTemplated Hollow PhospholipidTemplated Oligonucleotide NanoparticlesTreatment of Depressive DisordersTreatment of Neuropathic PainXCUR17-Psoriasis IL-17RA

6-APPROVAL Lyrica: Fibromyalgia7-PLATFORM A Modular Extracellular Sensor Architecture for Cell-Based B

Enhanced Gene Expression for Gene Therapy ApplicationsExosome TargetingInducible Cysteine Protease Autoprocessing of Recombinant PrMembrane Coatings pH Sensitive Anticancer Drug DeliveryNano-devices for local drug delivery, which are immobilizedStem Cell Therapy to Generate Cholinergic Neurons


ENERGY & SUSTAINABILITY PIPELINE


Phase Title1-RESEARCH Catalytic Methane to Ethylene Conversion over Mixed Oxide-Su

Deriving hydrogen from bioalcohols in water without producinDoped SnSe single crystals: ultralow thermal conductivity anDoped Tin Selenium Single CrystalsPAH Scavenger System (ExBox)PhotocatalystPhotocatalytic CompositeProtective cathode coatings for lithium-ion batteriesTin-Based 'Perovskites' for Solar Cell Production

2-RESEARCHVALIDATION

Algorithm for Electric Charging Station PlacementAll-Carbon Counter ElectrodeCarbon Nanoparticle for Energy StorageConjugated Polymers and their use in Optoelectronic DevicesCrumpled Graphene Coated Si NanoparticlesEpoxidation of Unsaturated HydrocarbonsFunctional monolithic polymeric organic framework for ag captureGraphitized Li-Ion BatteriesIntegrated Solid Oxide Fuel CellsLead-Free Solar CellsMethane/Nat Gas-Powered SOFCNanocomposites for Energy StorageNew Column Technology for the Efficient Capture of Heavy MetNew Ion Exchange Column Technology for Removal of Cr(VI) andNovel Batteries for Medical DevicesOrganic Photovoltaics w/Nickel OxidePolymeric Organic FrameworksSMOFC Battery CathodeSolar Cell CoatingSolid Oxide Fuel CellsSolid State Solar CellSolution-Processed High Mobility Inorganic Thin-Film TransisStretchable Batteries with Self-Similar Serpentine InterconnSynthesis of Layered Metal Sulfide Ion-ExchangersSynthesis of Porous Amorphous Metal Sulfide Ion ExchangersWater Detoxification Method

3-COMMERCIALVALIDATION

Carbon Nanotubes for PhotocatalysisElectrode Material Composed of Graphene-Composite MaterialsGLi ion exchange materials from brines and seawaterGold Isolation MethodHeavy Metal Removal and Gas Separation (title on Fbox: cost-effective chalcogenide po..Material Compossed of Graphite Network Formed from ReconstitPolymeric Blends Formed by Solid-State Shear PulverizationReactively Sputtered TiO2 Nanocomposite Thin Films for PhotoRemoval of Heavy Metal and Radioactive Pollutants from WaterSi Nanoparticles for Rechargable Lithium Batteries

ENGINEERING & TECHNOLOGY PIPELINE

23

Phase Title1-RESEARCH All-Carbon Spin Logic

Bipolar Magnetic JunctionComputing Logic FamilyDesign and Simulation of a Snapshot Multi Focal InterferometDielectrostrictive sensors for shear stress measurement, proEmitter-Coupled Spin Transistor LogicGate Tunable Nanoscale MemristorsHigh-Speed Magnetic Memory DeviceIntegrated On-Chip Thermocouple ArrayISOLATION OF PHOSPHORENE AND RELATED AMBIENT-REACTIVE NANOMAMagnetic Diode Based Programmable LogicMolecular Quantum Interference and Electronic DevicesMonolithically Widely Tunable Quantum Cascade Lasers Based oNeighbor Discovery in Wireless Networks via Compressed SensiNew Class of Molecular Iodosalts for Use in Next Generation Solar CellsNoncentrosymmetric Metal Electrodes for Ferroic DevicesNovel Logic Family w/Nanowire TransistorsNovel Protective Polymers for CircuitryOrganic FerroelectronicsSpin-Diode Logic FamilyTransverse ThermoelectricsTwo Qubit GateUltralow Power Carbon Nanotube Logic Circuits


Antiambipolar Heterojunctions from SemiconductorsAtomic Force Electroluminescence MicroscopyAutoLum: Precise Automatic Camera and Display Calibration AlBridge Enhanced Nanoscale Impedance MicroscopyBroad Frequency Electric Field SensorContactless Probe for Detecting Buried Conducting LayersDeducing Charge Density Gradients in Doped SemiconductorsDesign Techniques for Area and Energy Efficient Time DomainDirect Conversion of Infrared Images with High Conversion GaGate tunable p-n heterojunction diodeHigh Speed/Low Dose Multi-Objective Autonomous Scanning Materials ImagingImproved Nonlinear Optic Glassy Fiber and Thin FilmMagnetic Field SensorsNovel Separator for Electicity Storage DevicesPortable cell-free molecular sensing platformSilver Cathode for Lithium BatteriesSynthesis of borophenesTEM Nanostructure Characterization DeviceTracking Circuit for Hardware Security and ReconfigurationTwo Dimensional Assembly of Graphite Oxide Single Layers, anWiFMWireless Devices for Virtual Reality ApplicationsZirconium-Oxide Tunnel Barriers


3D Printing of NanocompositesBarium Titanate WaveguidesHot Pressing Method for TransistorsHybrid Thin-Film TransistorsLow Voltage Organic Electro-opticsMetal Oxide Thin FilmsOrganic SemiconductorsOrganic Transparent ElectrodesPlanar Photonic Jet Lens for Small Spot-Size and Large Field ViewPrintable Dielectrics for Electronic DevicesSingle-Molecule Protein Arrays Enabled by Scanning Probe BloStretchable Si Integrated CircuitsThiophene-based materials for optoelectronicsTransparent Conducting Graphene-Silica Thin FilmsWireless Skin Hydration Sensor with Methods and Uses

4-MARKET Electrostatis Multitouch Haptic Display

MATERIALS & INDUSTRIAL PROCESSES PIPELINE

Phase Title2-RESEARCHVALIDATION

Single Photon Detectors & ImagersStress Manipulated Coating for Figure Reshape of Optics MirrorsSubstrate-Independent Anticoagulant and Antibacterial CoatingsSynthesis of Uniform Gold Nanoparticles through Reductive GrThickness Sorting of 2D NanomaterialsTri-Pyramid RobotWater Processable Graphene OxideWhisker SensorZinc Sensor for MRI


A Novel Poly (Diol-Co-Citrate) Hydroxyapatite Composite For Clinical Fixation De..Additive Manufacturing At Phase BoundariesAdhesive Polymer CoatingAluminum Superalloys for Use in High Temperature ApplicationCD-MOFs for Storage of Active IngredientsCeramic CompositeCNT Reinforced CementConductive Tin and Zinc-Doped Thin FilmsControlling Charge Injection in OLEDsCrosslinkable Polymer DielectricsElectron-Blocking Layer For Improved Organic PhotovoltaicsEnumerative Generator of Hypothetical Metal-Organic FrameworFabrication of Metal Composite Thin FilmsGas-absorbing Metal Organic FrameworksGlobal Thermal Control of Additive ManufacturingGraphene Oxide PaperGraphite Nanoplatelet DispersionImproved Power Conversion For Organic PhotovoltaicsIntense Pulsed Light Annealing of Graphene InksInterfacial Shear-Flow Additive ManufacturingKinetic Separation of Olefin/Paraffin with MOFMajority Graphene 3D-Printed CompositesMETHOD AND APPARATUS FOR DOUBLE-SIDED INCREMENTAL FLANGINGMethod of Epitaxial Growth of MgOMethod to Improve Paint Production with Titanium OxideMicro-surface Texturing SystemMicro-Textured SurfacesMonolithic, Multi-Component Solid Oxide Fuel Cells from MultMultifunctional Bio-Inspired Coating Method For ModificationNanocomposite Film and Paper ProductionNanoporous MaterialsNanotube Reinforced CementNovel Materials for Polymer Light Emitting DiodesNovel Ni-Based AlloysNovel Organic Self-Assembled NanodielectricsNovel Solid Organic Host Silicon Matrix PolymerNucleic Acid-Metal Organic Framework (MOF) Nanoparticle ConjOrganic Photovoltaic CellsOrganic Semiconductor MaterialsProximity Sensor Based on CantileverPurification Of Carbon Nanotubes By Electronic Structure ViaSemi-conducting NanotubesSequestration and Detection of Carbon Dioxide with a Metal OSequestration and Detection of Harmful Chemicals in a NanopoSilole-Containing PolymersSuperlattice DielectricsTransparent Nanowire TransistorsUnconventional Electro-optic Chromophores

4-MARKET Advanced MaterialsGraphene Ink for Gravure PrintingGraphene Ink for Screen PrintingHigh Conductivity Graphene InksSolid-State Shear Pulverization of Neat Polyesters Yielding

Phase Title1-RESEARCH An Organo-Lewis Acid as Cocatalyst for Cationic Homogeneous

CxPbX3: perovskites for gamma-ray detection applicationsDuctile Magnesium AlloysGradient Spray Coating Polymer Pen ArraysHigh Temperature Steel for Steam Turbine ApplicationsIn Situ Photocatalytic and Thermocatalytic ActivitiesNovel X-Ray and γ-Ray Detector MaterialOil Soluble Organo-Silver Additives as High-Temperature AddiPhotonic Crystal Built with Nanoparticles and Spacer GroupsPolysulfide compounds for environmental remediationProduction of Substituted Imidazole MoleculesSilica Poymer Pen LithographySynthesis of 2-Aryl IndolesSynthesis of Priviledged 7-Membered Ring Molecules


2D Nanomaterial SortingA Universal Method for Production and 3D-Printing of High-PaAdhesive Hydrogels for SurgeryAn Automated Toolpath Generation Method for Double Sided IncAnti-microbial hydrogel coatingsArrays for X-Ray Optics LaminationAtomic Force Photovoltaic MicroscopyBiocompatible HydrogelsCompression and Aggregation-resistant Particles of CrumpledDOPA-Melanin FilmsEfficient Thin-Film SynthesisElectro-Optic ModulatorEncapsulation of Single Walled Carbon Nanotubes Via Self-AssEnhanced Strength Cement CompositesExtra Strength Magnesium AlloysExtra-Strength Hydrogel AdhesivesFlash Reduction of Graphic Oxide to GrapheneFluorescent Imaging of Graphene-based MaterialsGas-Phase Deposition in MOFGraphene Concentration MethodGraphene-Titania Nanocomposite PhotocatalystsHigh Accuracy Double-Sided Incremental FormingHigh Energy Density NanocompositesHole Array FilmsHydrogel Wound Dressing With Controlled Ion Release PropertiesImaging for SteroidIsolation of single-walled nanotubesLaser-Assisted Oxide NanopatterningLaser-Induced Plasma Micromachining (LIPMM)Low-Cost Semiconducting Single-Walled NanotubesMagnetic Shape-Memory FoamMaskless Nano-PatterningMesoscale Metallic Pyramids With Nanoscale TipsMethod for Fabricating Soft and Hard Lunar, Martian, and AddMicro Drug Delivery DeviceMulti-layer 2D perovskites for solar cell applicationsMultifunctional NanocompositesNano Fountain PenNanodiamond Particle ComplexesNanoparticle Sorting Method; Improved Nanoparticle Processing for Energy UseNanoscale Doping for Transparent Conducting OxidesNanoscale Self-Assembling Organic DielectricsNanoscale Subsurface ImagingNitrogen-Free Plant Polyphenol Derived CoatingsNovel MOF based on Azolium SaltsNovel Synthetic Route to Diazaperopyrenium Dication and thep-type Transparent ConductorsPbTe Composite Material for Thermoelectric DevicesPlant Polyphenoal Coatings & MethodsPolycrystal Memory Foam for Energy ApplicationsProgrammable Soft Lithography: Solvent-Assisted Nanoscale EPtAuCu nanocatalyst for electrochemical hydrogen evolutionRoute to Diazeperopyrenium DicationSelf-Assembled Monolayer Mediated Silica Coating Of Silver NSelf-assembly of Oligo Amphiphiles

SOFTWARE & SERVICES PIPELINE


Phase Title1-RESEARCH Method and Apparatus for Physical and Medium Access Control

Olfactory based virtual reality with sub-second timescale co2-RESEARCHVALIDATION

A Method for Acquiring Intentionally Limited Data and the MaEfficient Incremental Algorithm for Minimum Area RetimingFourier-domain Mobility Spectrum Analysis (FMSA)IchefLow cost sensing and communication system for rotorcraftMint (Materials Interface)Net Theater: Dynamically Constructing Theatrical ExperienceNovel Logic Encryption Designs for IC ProtectionPrivate Data Networks: Federated Databases for Mutually DistRadio Resource Management in Large Wireless NetworksStreet-Level IP Geolocation TechnologySystem and method for multi user two-way rangingTop Down Proteomics Software LibrariesUser-Driven Indoor Visibility Localization with WayfindingVirtualCar: Computational simulation of self-propelling auto


6DoS (Six-degrees-of-separation)A method for speeding the learning of equalization parameterAutoCog: Measuring Description-to-permission Fidelity in AndCentral Line Insertion Training CurriculumEqualization Preference Learning AlgorithmFinding Trending Topics on Social MediaMAT2C: A MATLAB-to-C TranslatorMotorized Software: Controlled CalibratorNorthwestern Anagram Test (NAT)Northwestern Assessment of Verb Inflection (NAVI)Northwestern Assessment of Verbs & Sentences (NAVS)Northwestern Naming Battery (NNB)Real-Time Patient Volume Predictor InstrumentREPET (REpeating Pattern Extraction Technique)SAFE (Situational Awareness for Events): A Data VisualizatioSequential Action ControlSimulation-based Mastery Learning for Peripherally InsertedSimulation-based Mastery Learning for Ultrasound Guided PeriSocial Media-Based Preference Determination and RecommendatiThe Digital LoftTreatment of Underlying Forms (TUF)Twitter Profiling/MindshareUranine: Real-time Privacy Leakage Detection and Prevention

4-MARKET A Method to Search Audio Synthesizers Using Vocal ImitationAdministrative Network ManagerAdvanced Encryption SystemAlgorithm to Produce High Performance Steel & AlloysAppShield: A Proxy-based Data Access Mechanism in EnterpriseArtificial Intelligence & WritingbloXroute: a Scalable Trustless Blockchain Distribution NetworkChematicaDigital Language LabIntegrated Scheduling SoftwareMarketing Algorithm Based on Social MediaOptimization Software

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INVO Inventive Activity FY2019 - confidential...FILED PATENT APPLICATIONS BY TYPE FIG. 11 ISSUED...

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Transcript of INVO Inventive Activity FY2019 - confidential...FILED PATENT APPLICATIONS BY TYPE FIG. 11 ISSUED...