InvestorPresentation– October2017MarkDuff,CEO&BenNaccarato,CFO

NASDAQ:PESI

SafeHarborCertainstatementscontainedwithinthispresentationmaybedeemed“forward-lookingstatements”withinthemeaningofSection27AoftheSecuritiesActof1933,asamended,andSection21EoftheSecuritiesExchangeActof1934,asamended(collectively, the“PrivateSecuritiesLitigationReformActof1995").Allstatementsinthispresentationotherthanastatementofhistoricalfactareforward-lookingstatementsthataresubjecttoknownandunknownrisks,uncertaintiesandotherfactorswhichcouldcauseactualresultsandperformanceoftheCompanytodiffermateriallyfromsuchstatements.Thewords“believe,”“expect,”“anticipate,”“intend,”“will,”andsimilarexpressionsidentifyforward-lookingstatements.Forward-lookingstatementscontainedhereinrelateto,amongotherthings:theCompany’sabilitytodeveloporadoptnewandexistingtechnologies;anticipatedfinancialperformance;growththroughacquisition;leaderinthemixedwasteindustry;positionedtobenefitfrommixedwastemarketopportunities;geographicstrongholds;andallotherstatementswhicharenotstatementsofhistoricalfact.

WhiletheCompanybelievestheexpectationsreflectedinsuchforward-lookingstatementsarereasonable,itcangivenoassurancesuchexpectationswillprovetohavebeencorrect.Thereareavarietyoffactorswhichcouldcausefutureoutcomestodiffermateriallyfromthosedescribedinthisreport,including,butnotlimitedto:generaleconomicconditions;increasedcompetitivepressures;theabilitytomaintainandobtainrequiredpermitsandapprovalstoconductoperations;theabilitytodevelopnewandexistingtechnologiesintheconductofoperations;changesinfederal,stateandlocallawsandregulations,especiallyenvironmentalregulations,orininterpretationofsuch;andthecommercialviabilityofouron-sitetreatmentprocess.

TheCompanybelievesthepresentationofEBITDAandAdjustedEBITDAisrelevantandusefulbyenhancingthereaders’abilitytounderstandtheCompany’soperatingperformance.TheCompany’smanagementutilizesEBITDAandAdjustedEBITDAasmeanstomeasureperformance.TheCompany’smeasurementsofEBITDAandAdjustedEBITDAmaynotbecomparabletosimilartitledmeasuresreportedbyothercompanies.

TheCompanymakesnocommitmenttodiscloseanyrevisionstoforwardlookingstatements,oranyfacts,eventsorcircumstancesafterthedatehereofthatbearuponforwardlookingstatements.

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NASDAQ:PESI

CompanyOverview

Treatment ServicesTeamsofprofessionalswithinnovativetechnologiesandtrainedworkforcetoprovideradiologicalprotectionandenvironmentalremediationservices.

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Perma-Fixisfocusedonthreeprimarymarketswithuniquecapabilitiesineachofthesesegments:

Permitted,licensed,andoperatingfacilitiestreatingamagnitudeofcontaminatedwastesforeconomicandcompliantdisposal.

ProvidingsolutionstofutureradioisotopeneedsinworldwidemedicalmarketsbyleveragingdeepexpertiseinradiologicalchemistryandnuclearR&D.

Medical

NASDAQ:PESI

MarketOverview

“DOEwasresponsibleforover80percent($372billion)oftheU.S.government'sfiscalyear2016reportedenvironmentalliability,mostlyrelatedtonuclearwastecleanup. DOE'stotalreportedenvironmentalliabilityhasgenerallyincreasedsincefiscalyear2000.AccordingtoauditdocumentationrelatedtoDOE'sfiscalyear2016financialstatements,50percentoftheDOE'senvironmentalliabilityresidesattwocleanupsites:theHanfordSiteinWashingtonStateandtheSavannahRiverSiteinSouthCarolina.”- GAO

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Today,underthedirectionoftheU.S.DOE,Hanfordisengagedintheworld'slargestenvironmentalcleanupproject;Expectedtocontinueuntil2030andcostover$100billion.

NASDAQ:PESI

MarketOverview

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Commercial• Power – Over100reactorscurrently

operatingintheUS;over400world-wide.• Mining – Continuedissuesatminingsites

withtailingsthatincludehighlevelsofnaturallyoccurringradioactivematerials(NORM).

• OilandGas – DrillingpracticesalsorealizinghighlevelsofNORM.

International• Canada/Europe/Mexico– Beginningto

budgetandremovelegacywastesandcontaminationfornuclearoperations.

DepartmentofEnergy• EnvironmentalManagement(EM)- Over100activesitesintheUSwitharea

equaltoRhodeIslandandDelawarecombined;approximately88milliongallonsofliquidwastestoredinundergroundtanks;about400millionhazardouswasteshipmentsannually,about3Mareradiological.

• NationalNuclearSecurityAdministration(NNSA)-Maintainsthefacilitiestoensurethesafe,secure,andeffectivenucleardeterrentrequiringcleanupoflegacywastesandcontinuousgenerationofnewlygeneratedwastesfordisposition.

DepartmentofDefense• Navy - NuclearpropulsionandNAVFAC(nearly$2B2017-2019)missionsresult

inradiologicalandhazardouswasteswhichrequiretreatmentanddisposal.• UnitedStatesArmyCorpsofEngineers(USACE)– Over$1Binremediation

contractstobeprocured2017-2018.

NASDAQ:PESI

Background

• Perma-Fixisaleadingproviderofnuclearwastetreatmentservices• Specializinginthetreatmentofwastethatisbothradioactiveand/orchemically

hazardous

• Wastegeneratedbycommercialcustomers,utilities,hospitals,researchfacilities,andthegovernment

• EstablishedlaboratoriesandR&Dcapabilitiestosolveproblemsquicklyandefficiently

• Long-standingrelationshipswithgovernmentagenciesincludingDOE,NRC,andNNSA

• Nuclearservicesgroupprovidesonsitepersonnelandtechnologiesforenvironmentalprotectionandcleanupprograms• Industryleaderinradiologicalprotectionservicestogovernmentandcommercialclients

• Environmentalrestorationandwastemanagementservicesforcomplexcleanupprojectsincludingradiologicalandhazardouscomponents

• Maintainsinstrumentcalibrationlaboratorywithover6,000instrumentstosupportnuclearindustry

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NASDAQ:PESI

WasteTreatmentFacilities

• Threefixed-basedfacilitieswithactivepermitsandlicensestotreatmostwastestreamsintheindustry• Trainedandexperiencedworkforcewithaveragetenureover12yearsatPerma-Fix• Perma-Fixownsallthefacilitieswithsubstantialcapitalinvestedthroughthelifeoftheplants

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Perma-FixFlorida- Gainesville,FL

Radiological,transuranic,andlargecomponents

DSSI- Kingston,TN

Radiological,liquids,andPCBs

Perma-FixNorthWest- Richland,WA

Industrial,Radiological,andR&D

NASDAQ:PESI

MassiveBarrierstoEntry

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• HighlyregulatedatStateandFederallevels• NuclearRegulatoryCommissionthroughstateregulators• EnvironmentalProtectionAgencythroughstateregulators• Stateregulatorsforotherairandwaterpermits

• Technology• Patented(40+)andproprietarychemicaltreatmentprocess• Treatmentofnuclearwasteiscomplexandrequiresmultipletechnologiesandmultiplesteps

• Experience• Unparalleledexperienceandtrackrecordoffacilitiessuccessfullytreatingnuclearwaste30+years

NASDAQ:PESI

NuclearServices

• Servicesgroupprovideswastepersonnelandcapabilitiesonclient’ssitesforavarietyofindustrialandgovernmentclients• MajorcontractswithDepartmentofEnergyfacilities• Expansionintocommercialandinternationalhelpingdiversifyrevenue

• CapabilitiesincludehealthphysicsandremediationofnuclearmaterialsfortheDOE,DOD,federalagenciesandcommercialcustomers

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NASDAQ:PESI

GrowthStrategyNewgrowthstrategytoexpandmarketbaseinbothTreatment&ServicesSegments:

ü Expansionofwastetreatmentcapabilitiesandincreasingefficiencyofexistingfacilities• Broadenmarketbasein2018throughexpansionoftreatmentcapabilitiestoincludewaterandmetalstreatment(Na,Hg)

withinexistingfacilities• Partneringwithlargerfirmstoprovidetotalwastemanagementservicesandtechnologylaunchesinourfacilities• ClosureofM&ECfacilityscheduledforcompletioninearly2018toconsolidatetechnologies,staff&capabilitiesreducing

costsover$5M/yr.• LeveragingouruniqueR&Dcapabilitiestoprovidecomplexwastedispositionsolutions

ü RevisedbusinessdevelopmentprogramtobroadenmarketpotentialofNuclearServices• Reorganizedmarketingandbrandingapproachtointegratebothsectors• Implementedcompleteproposalcentergenerating45proposalsyeartodate• In2017,Perma-Fixhasrealizedawinrateof63%,with38bidsannouncedwinning24withannualvaluesover$19M

ü Broadeningmarketpotentialthroughclientexpansion• Marketingfocusonpower,municipalandscrapmetalindustriesadding8newclientsyeartodate• SeveralnewwinsinCanadasupportinglargescalecleanupefforts

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NASDAQ:PESI

Tc-99mMarketOpportunity

• Tc-99misthemostwidelyusedmedicalisotopeintheworld• Allowsmedicalpractitionerstoimageinternalbodyorgans• Usedin80%-85%ofthe25Mdiagnosticnuclearmedicalprocedureseachyear• Commonproceduresincludecardiacimaging,cancerdetection,gastrointestinalissues,aswellasimagingofthebrain,kidney,spleenandinfections

• TheradioisotopemarketinEuropealoneisexpectedtoreach$1.6Bin2017,upfrom$1.1Bin2012• Nearlyalloftheworld'ssupplycomesfromthethermalfissionofhighlyenricheduranium(HEU)targetsinasmallnumberofhighlyspecializedreactors

• Currentprocessiscostlyandunreliable;raisesseriousproliferationconcerns

• CurrentandplannedreactorshutdownswillputbillionsofUSDinmedicalproceduresatrisk

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NASDAQ:PESI

Perma-FixMedical*• CompletedinitialdevelopmentofnewprocesstoproduceTc-99mformedicaldiagnostictests

• ExpectedtosolveworldwideshortagesofTc-99m• Farlessexpensiveprocess• Doesnotrequiretheuseofgovernment-subsidized,weapons-gradematerials• Designedtoimprovesafetyandsecurityofradioactivematerials

• Processencompassesfullproductioncycle:reactortofinalmedicalsupply• Easilydeployedworldwideusingstandardresearchandcommercialreactors• Eliminatestheneedforspecialpurposereactors• StabilizestheworldwidesupplyofTc-99mbydecentralizingproduction

• Patentedprocessvalidatedattheleadingglobalresearchinstitutes

• Plantosubmit‘fast-track’505(b)2forregulatorymarketingclearance• Noclinicaltrialsrequired

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*Perma-FixEnvironmentalServicesowns60.5%ofPerma-FixMedicalS.A.

NASDAQ:PESI

IsotopeProduction

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CurrentUraniumProcess*

Perma-FixMolybdenumProcess*

=

=

N

*Source:NATIONALRESEARCHCOUNCILOFTHENATIONALACADEMIES

NASDAQ:PESI

Sr.ManagementTeam

Mark Duff, President/Chief Executive Officer, 30 years of experience in the DOE & DOD environmentaland construction markets. For the past five years, Mr. Duff has been responsible for the successfulcompletion of over 70 performance-based projects at the Paducah Gaseous Diffusion Plant (PGDP), KYoverseeing a five-year project with a total value of $458 million. Prior to the PGDP project, Mark was a seniormanager supporting Babcock and Wilcox (B&W).

Dr. Louis Centofanti, Executive Vice President of Strategic Initiatives, founded Perma-Fix in 1991.Founded PPM, Inc., a hazardous waste management company. PPM’s revenues grew to $15 million at whichtime it was sold to USPCI. Under Dr. Centofanti’s leadership (Senior Vice President), USPCI was sold for $600million (2 years after purchase of PPM). Served as senior official to the U.S. Department of Energy under theCarter Administration.

Ben Naccarato, Chief Financial Officer, joined Perma-Fix in 2004. He brings 29 years experience insenior financial positions in the waste management and used oil industries. Previous positions include ChiefFinancial Officer for a privately held fuel distribution and used waste oil company, and Director of FinancialPlanning and Analysis with Safety-Kleen Corp.

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NASDAQ:PESI

H12017FinancialHighlights

• Revenueincreasedto$25.4millionversus$24.8millionforthesameperiodlastyear• RevenuefortheTreatmentSegmentincreased29%to$19.7millionfrom$15.2millionforthesameperiodin2016

• Grossprofitwas$5.1millionversus$1.9millionforH12016• Grossmarginincreasedto20.0%from7.4%forthesameperiodlastyear

• Achieved$1.4millionofadjustedEBITDA*• $2.9millionimprovementfromH12016

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Freedup$5.9millioncash,replacingclosurepolicyatPFNWfacilitywithnewbondingmechanism;proceedsusedtorepaytheentirelineofcreditwithremainingfundsusedforgeneralworkingcapitalpurposes.

(In thousands) 2017 2016Loss from continuing operations (1,901)$ (11,980)$

Adjustments:Depreciation & amortization 2,288 1,796 Interest income (71) (47) Interest expense 189 276 Interest expense - financing fees 18 85 Income tax expense (benefit) 147 (3,130)

EBITDA 670 (13,000)

Research and development costs related to Medical Isotope project 750 854

Impairment loss on tangible assets — 1,816 Impairment loss on intangible assets — 8,288 Write-off of prepaid fees resulting from impairment

loss on tangible asset — 587

Adjusted EBITDA 1,420$ (1,455)$

Six Months EndedJune 30,

NASDAQ:PESI

InvestmentSummary

ü Positionedtobetheleaderinthemulti-billiondollarnuclearservices&treatmentmarket• AggressivebiddingonnewServicecontracts;providesstableandpredictablecashflow• Expansionintonewwastestreamsthateclipsecurrentmarkets;incrementalrevenuegeneratesveryhigh

grossandoperatingmargins

ü Nearlyinsurmountablebarrierstoentryü Turnaroundandreturntoprofitability

• Forecastingstrongyear-over-yeargrowthinrevenueandEBITDAfor2017• Furtherreductioninfixedcostsof$4-5millionannually;tobefullyrealizedbyJanuary2018

ü Disruptivemedicalisotopeproductiontechnology;positionedtobethemajorsupplierinamulti-billiondollarindustry

ü Significantandundervaluedassetbase• 3uniqueandirreplaceablefacilities• $15.6Mofcashsecuringregulatoryclosurerequirement• Own60.5%ofapublicmedicalisotopesubsidiary

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NASDAQ:PESI

KeyStatistics

NASDAQ: PESI

CurrentPrice:(9/28/2017): $3.95

SharesOutstanding: 11.7M

MarketCap: $46.2M

FiscalYearEnd: December31

InsideOwnership: 6.2%

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