Introduction to the Course of Endocrine and Metabolism 2012, International University of Africa

8/3/2019 Introduction to the Course of Endocrine and Metabolism 2012, International University of Africa

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EndocrineandMetabolism

AtifHassanKhirelsied,B.Sc.,M.Sc.,Ph.D.f

Facult

ofMedicine

InternationalUniversityofAfrica,Khartoum,Sudan


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Theimportance

of

endocrine

system

Functionalcoordinationofbodysystems.

.

Conservationofhomeostasis.

Adaptationtoenvironmentalchanges.


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Courseintroduction

Number: FMHS511

Title: EndocrinologyandMetabolism

Coordinator: Dr.AtifH.Khirelsied(phone:0122169743)

Duration: 6Weeks

Credithours: 6hrs

committee

Dr.Atif

H.

Khirelsied,

Dr.

Fatma Elsmani,

Dr.

Ibtisam Ali,

Prerequisites

u r ona oc em s ry, n ro uc on o es u yo seases,

ManandEnvironment,GrowthandDevelopment,Gastro

intestinaltract.

Facilitiesand Lectureroom(150students),computerandmultimedia

Requirements projectors,dissectionroom, museum,libraryandlaboratory.


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characteristicsof

the

endocrine

system

and

elaboratesonthemorphology,biochemistry,

physiologyand

pathology

of

various

glands

endocrinesystem.


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Course GeneralObjectives


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,

studentsshouldbeableto;

1. Describetheoverallorganizationoftheendocrine

systemin

the

human

body,

and

identify

the

major

glandsandtheirlocations.


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U onsuccessfulcom letionofthiscourse the


2. Outlinetheroleofhormonesinthecontrolof

bodyfunctioning

and

describe

the

importance

ofhormonesinhealthanddiseases.


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Uponsuccessfulcompletionofthiscourse,the


3. Identifydifferentclassesofhormonesand

hormonereceptors,

and

describe

the

principles

o mo ecu ars gna nga ce u ar eve .


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Uponsuccessfulcompletionofthiscourse,the


4. Describethemajormetabolicpathwaysof

carbohydrates,lipids,

proteins

and

nucleotides

metabolism,andexplainhowthesepathways

system.


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,


5. Identifytheimportantclinicalconditions

associatedwith

hormonal

and

metabolic

disorders,andlearnhowtoevaluateendocrine

sor erscommon yseen npr mary ea t

.


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,


.

commonlyusedinhormonalassays.


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Course specificLearningObjectives


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1.Identify theorgansandtissuesoftheendocrine

systemanddescribetheirgeneralmorphologicaland

.

2.Define thevariousformsofcellularcommunication

andsignalingsystems(i.e.,endocrine,paracrine,


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3. Describethevariousclassesofhormonesbothin

termsoftheirstructuresandphysicochemical

propertiesaswellasmechanismsofaction.

4. Recognize thetypesofcellularresponsestohormones

anddefinepositiveandnegativefeedbackand

describetheirroleinregulatingbloodlevelsofvarious


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5. Identify thetarget,representativeactions,andsecretory

controlofthehormonesofthe;

. ,

6. pituitarygland,

7. pancreas,

9. parathyroidglands,

10. adrenalcortexandmedulla,

11. ineal land,th mus,ovaries,andtestes.


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5. Define generalprincipleofgenesexpressionandpeptide

hormonesynthesis,andrelatethesetocontrolof

hormonesynthesisandsecretion.

6. Discuss howhormonescoordinateandintegratethe

.


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major

metabolic

pathways

of

carbohydrates,

lipid,

amino

acidandnucleotidemetabolism.

8. Defineprostaglandins,whataretheymadeof,andwhat

aretheireffects?


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9. Recognize thecausesofdwarfism,giantism,acromegaly,

diabetesinsipidus,diabetesmellitus(Type1andType

2 cretinism m xedema Grave'sdisease sim le oiter

andCushing'ssyndrome.

.

andendocrinefunctiontests.


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11. Recognize the

endocrine

function

of

the; kidneys

Heart

Adiposetissues


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Course PBLSessions


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. .

2.Cushingssyndrome.

3.Diabetesmellitus.

4.Primaryinfertility.

th Elwathig)


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1. Studentsareexpectedtoattendlectures,tutorialsand

practical/studygroupsessions.

2. Failuretomeettheminimalattendancerequirements(75%ofecourseac v es mayresu nyou e ng eeme ne g e

forassessment.

.

withoutexcusewillnotbeallowedtositforthefinalexamand

will

be

deemed

fail.


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1.Readandfamiliarizehim/herwiththecontentsofthe

coursesyllabus.

2.Participateincourseactivitiesviaclassattendance,

discussion,and

note

taking,

seminar

preparation

and

presentation.

3.Readandstudyassignedreadingspriortobeingtested

over

the

material.


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Course Assessment


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Finalexamination:

accountsfor(70%)ofthetotalpoints

cons stso s ,s ortnotes ,

Thecontinuous

assessments:

accountsfor30%ofthetotalpoints

Include midcourse test re orts and PBL activities.


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Studentsscoreswillbegradedaccordingtothefollowing

scale.

core

Grade F C B B+ A


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Studentsfeedback(questionnaire).

Facultycommentsandobservations.

Analysisofexaminationresults.


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Course Timetable


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Davidson'sPrinciplesandPracticeofMedicine20thedition(2006).NicholasA.

, . . . .

HarpersIllustratedBiochemistry,28th edition(2009). RobertK.Murray,Victor

W.

Rodwell,

David

Bender,

Kathleen

M.

Botham,

P.

Anthony

Weil,

Peter

J.

enne y. as c c ence, c raw .

Biochemistry: ACaseOrientedApproach,6thEdition(1990).RexMontgomery,

Spector andThomasW.Conway.MosbyYearBook.

BaileyandLove'sShortPracticeofSurgery24edition(2007).R.C.G.Russell,

NormanWilliams

and

Christopher

J.K.

Bulstrode .

Oxford

University

Press.

ReviewofMedicalPhysiology,22ndEdition(2005).WilliamF.Ganong.LANGE

BasicScience,McGrawHill.

AnAidtoClinicalSurgery,6th edition(1998).PeterR.Scott(Author),B.P.

Waxman

Editor

RobinC.N.

Williamson

Editor .

Churchill

Livin stone.

McMinn's ColorAtlasofHumanAnatomy,4thedition(1998).P.H.Abrahams,

R.T.Hutchings,S.C.Marks.MosbyYearBook.


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Introduction to the Course of Endocrine and Metabolism 2012, International University of Africa

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