Genetics. Vocabulary DNA Extra $100 $200 $300 $400 $500 Punnet Squares.
Introduction to Genetics Punnet...
Transcript of Introduction to Genetics Punnet...
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Introduction to Genetics
Punnet Squares - determining the outcomes
of a cross
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Traits Which trait will the offspring have?
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M O T H E R S
F A T H E R S
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vocabulary • Gene – location on a chromosome for a certain
trait.
• Allele - one form of a gene. • Cross – fertilization (mate). • Principle of Dominance – an organism with at
least one dominant allele will express that trait. The recessive trait will be expressed only when both alleles are recessive.
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Law of Segregation
• During gamete formation, the alleles for each gene segregate from each other, so that each gamete carries only one allele for each gene
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Genotype - allele combination determines Phenotype - observable characteristics (the way an organism looks)
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Punnett Square
• A probability tool – used to predict the possible outcomes of a genetic cross
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Types of genotypes
• If both alleles for the trait are the same, the genotype is homozygous – homozygous dominant (AA) – Homozygous recessive (aa)
• If the two alleles for the trait are different, the genotype is heterozygous – Heterozygous (Aa)
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Some basic rules 1. Same letter for the same trait 2. Capital letter for dominant allele 3. Small letter for recessive allele 4. Dominant allele is shown first in each pair. Trait – eye color E = dominant allele e = recessive allele Homozygous dominant = EE Heterozygous = Ee Homozygous recessive = ee
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Monohybrid cross • Definition: A monohybrid cross is a cross between
organisms that differ in one trait. Step 1, make a key
Flower color In flowers, Red (R) is dominant to white (r)
Possible phenotypes/genotypes Red
RR Rr
White rr
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Monohybrid cross
• Step 2- write out parental genotypes
• Cross – Cross a white parent with a red parent
• Step 3 – Punnett Square
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Homozygous parents RR x rr
R E D p a r e n t
W H I T E
p a r e n t
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Genotypes and Phenotypes
Step 4 – record results Genotype
100% - Heterozygous (Rr) genotype Phenotype
100% - Red phenotype
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Heterozygous parents Rr x Rr
R E D p a r e n t
R E D
p a r e n t
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Genotypes and Phenotypes
25% - RR (homozygous dominant) genotype 50% - Rr (Heterozygous)genotype
25% - rr (homozygous recessive) genotype
75% - Red phenotype (RR + Rr) 25% - white phenotype (rr)
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Dihybrid Cross
• Definition: A dihybrid cross is a cross between organisms that differ in two traits.
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Dihybrid Cross
Possible gametes in the following genotypes: Genotypes Possible gamete combinations AABb AB,Ab Aabb Ab, ab aaBB aB aaBb aB,ab aabb ab AaBb AB,Ab,aB,ab
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Dihybrid Cross
R – red
r – white
T – tall t – short
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Dihybrid Cross RrTt x RrTt
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Genotypes RRTT (1/16) – 6.25 % RRTt (2/16) – 12.5% RrTT (2/16) – 12.5% RrTt (4/16) – 25% RRtt (1/16) – 6.25% Rrtt (2/16) – 12.5% rrTT (1/16) – 6.25% rrTt (2/16) – 12.5% rrtt (1/16) – 6.25%
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Phenotypes
RT red, tall (9/16) – 56.25%
Rt red, short (3/16) – 18.75%
rT white, tall (3/16) – 18.75%
rt white, short (1/16) – 6.25%
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Understanding the coin toss - Two possible outcomes. - Only one result.
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M O T H E R S
F A T H E R S
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Traits Which trait will the offspring have?
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Two possible alleles – one from each parent. Only one goes to each gamete.
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Dihybrid – two traits
Each parent has two coins
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Simply working with two traits
Heterozygous Smooth and Yellow
Heterozygous
Smooth and
Yellow
Surface R = smooth r = rough Color Y = Yellow y = green
RrYy
RrYy
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Dihybrid Cross RRTT x rrtt
RrTt R T R T R T R T
rt
rt
rt
rt
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Dihybrid Cross
SSbb x ssBB
tail length (S or s) - short is dominant - long is recessive color of fur (B or b) - brown is dominant - white is recessive
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Generations
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Or . . . Work with each trait separately.
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DOMINANT TRAITS RECESSIVE TRAITS
Eye coloring brown eyes grey, green, hazel, blue eyes
Vision
farsightedness normal vision normal vision normal vision
normal vision nearsightedness night blindness color blindness*
Hair
dark hair non-red hair curly hair full head of hair widow's peak
blonde, light, red hair red hair straight hair baldness* normal hairline
Facial features
dimples unattached earlobes freckles broad lips
no dimples attached earlobes no freckles thin lips
Appendages
extra digits fused digits short digits fingers lack 1 joint limb dwarfing clubbed thumb double-jointedness
normal number normal digits normal digits normal joints normal proportion normal thumb normal joints
Other
immunity to poison ivy normal pigmented skin normal blood clotting normal hearing normal hearing and speaking normal- no PKU
susceptibility to poison ivy albinism hemophilia* congenital deafness deaf mutism phenylketonuria (PKU)
• sex-linked characteristic